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8.1-8.3 WORKSHEET Section 8.1 – Identifying DNA as the - Mr

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8.1-8.3
WORKSHEET
Section 8.1 – Identifying DNA as the Genetic Material
KEY CONCEPT - DNA was identified as the genetic material through a series of experiments
MAIN IDEA: Griffith finds a “transforming principle.”
Write the results of Griffith’s experiments in the boxes below
Experiments
1. Injected healthy mice with R type
bacteria
Results (what happened to the mice?)
2. Injected healthy mice with S type
bacteria
3. Heat-killed the S type bacteria
and then injected them into
healthy mice
4. Mixed the S heat-killed with R
type bacteria and then injected
both of them into healthy mice.
The mice died.
Found live S type
bacteria in the
healthy mice
5. Which type of bacteria caused the deadly disease, the S type or the R type?
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________________________________________________________________________________________________
6. What was “transformed” in Griffiths experiment?
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7. What conclusions did Griffith make based on his experimental results?
__________________________________________________________________________________________________
________________________________________________________________________________________________
8. What were the three tests that Dr. Avery did that added to Dr. Griffith’s experiment?
a. ______________________________________________________________________________________
______________________________________________________________________________________
b. ______________________________________________________________________________________
______________________________________________________________________________________
c. ______________________________________________________________________________________
______________________________________________________________________________________
9. What was the conclusion?
__________________________________________________________________________________________________
________________________________________________________________________________________________
10. Describe what Dr. Hershey and Dr. Chase did, what was their experiment about?
__________________________________________________________________________________________________
________________________________________________________________________________________________
11. What was the conclusion?
__________________________________________________________________________________________________
________________________________________________________________________________________________
Section 8.2 – Structure of DNA
KEY CONCEPT - DNA structure is the same in all organisms
MAIN IDEA: DNA is composed of four types of nucleotides.
VOCABULARY
Nucleotide
Double helix
Base Pairing Rules
1. In the space at right, draw a nucleotide and label its three parts using words and arrows.
2. How many types of nucleotides are present in DNA?
_______________________________________________________________________________________________
3. Which parts are the same in all nucleotides?
_______________________________________________________________________________________________
4. Which part is different in all nucleotides?
_______________________________________________________________________________________________
MAIN IDEA: Nucleotides always pair in the same way
5. What nucleotide pairs with T?
_______________________________________________________________________________________________
6. What nucleotide pairs with C?
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7. In the space below, draw a DNA double helix. Label the sugar-phosphate backbone, the nitrogen-containing bases,
and the hydrogen bonds
Section 8.2 – Structure of DNA
Parts of the
DNA molecule
Overall shape
14.
Nitrogencontaining bases
Pyrimidines
17.
Purines
Backbone
15.
18.
16.
19.
20.
21. Base pairing rules:
A pairs with T
G pairs with C
Types of bonding
22
23.
Chargaff’s rules:
24.
Draw the complementary DNA strand
Section 8.3 – DNA Replication
KEY CONCEPT - DNA structure is the same in all organisms
MAIN IDEA:
Proteins carry out the process of replication
VOCABULARY
Replication
DNA Polymerase
DNA replication copies the genetic information of a cell
1. What is DNA replication?
__________________________________________________________________________________________________
________________________________________________________________________________________________
2. Where does DNA replication take place in a eukaryotic cell?
__________________________________________________________________________________________________
________________________________________________________________________________________________
3. When is DNA replicated during the cell cycle?
__________________________________________________________________________________________________
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4. If one strand of DNA had the sequence TAGGTAC, what would be the sequence of the complementary DNA strand? .
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________________________________________________________________________________________________
5. What roles do proteins play in DNA replication?
__________________________________________________________________________________________________
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6. What must be broken for the DNA strand to separate?
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7. Why DNA replication is called semiconservative?
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Use words and diagrams to summarize the steps of replication, in order, in the boxes below.
8.
9.
10.
MAIN IDEA:
Replication is fast and accurate
11. Human chromosomes have hundreds of origins of replications, where the DNA is unzipped so replication can begin.
12. DNA polymerase has a proofreading function that enables it to detect errors and correct them.
13. Why is DNA replication described as semiconservative?
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14. What are two major functions that DNA polymerase performs?
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8.3- DNA Replication
Match the following with the diagram below:
15. ______
Pairing of nitrogen-containing bases
16. ______
Sugar-phosphate backbone
17. ______
Newly synthesized strand of DNA
18. ______
Nitrogen-containing bases
19. ______
DNA polymerase
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