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Aurora Kinase Inhibitors Market - Global Industry Analysis, Size, Share, Growth, Trends And Forecast 2015 - 2023

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The Aurora kinases are enzymes which are crucial for cell proliferation. These enzymes are responsible for dividing genetic material of the parent cell during the process of mitosis by controlling chromatid segregation. The defect related to this pr
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Aurora Kinase Inhibitors Market Global Industry Analysis, Size,
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2015 - 2023
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REPORT DESCRIPTION
The Aurora kinases are enzymes which are crucial for cell proliferation. These enzymes are responsible for dividing
genetic material of the parent cell during the process of mitosis by controlling chromatid segregation. The defect
related to this process is largely associated with cancer genesis in human body. In this way active involvement of
aurora kinase enzymes in initiating cancer genesis has lead considerable attention of therapists to their inhibition in
the work towards cancer treatment. There are three kind of aurora kinase found in human body namely A, B and C.
Aurora C is mainly restricted to the process of spermatogenesis while remaining two are responsible various
tumerogenesis.
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Cancer is considered to the major causative factor for mortality worldwide with increasing incidence and prevalence
day by day. All regions of the world have seen continuous rise in number of cancer patients in past decade. WHO
predicted that annual cancer cases will reach to 19.3 million by 2025 from the 14.1 million annually in year 2012,
whereas annual cases in 2008 were 12.7 million of which 1.7 million were women newly diagnosed with breast
cancer that accounted for 20% in 2008. WHO mentions that cancer kills 8.2 millions globally out of which 522,000
woman from breast cancer. It is mentionable that incidence rate is still higher in developed region whereas death
rates are higher in less developed countries. In all the cancer types, number of patients suffering with head and
neck, gastrointestinal, breast and uterine cancer are highest.
Aurora family Kinase Assay/Inhibitor screening kits are designed to estimate the inhibitory effect of individual Aurora
activity in the test chemical accurately. Merck Millipore, MBL International, Perkin Elmer, SignalChem are some of the
leading companies which manufacture screening kits.
Geographically North American region accounts for the largest market share in this market which is followed by
developing Asia Pacific market and European market. The market for Aurora Kinase inhibitor is driven by continuous
increasing number of cancer cases and improving healthcare standard outside the developed world and
advancements in early diagnosis of cancer. However there are restrictions such as high cost involved in drug
development, lower spending capacity of poorer countries and need of real time clinical data. There are different
kind of biological therapies in oncology such as Tyrosine kinase inhibitor (includes erlotinib, imatinib, gefitinib,
dasatinib, sunitinib, ruxolitinib, etc.), monoclonal antibodies (includes trastuzumab, bevacizumab and cetuximab,
etc.) whereas some are in development stage such as Aurora Kinase Inhibitor (Hesperadine, VX-680). Currently there
is no molecule is approved in this market however there are almost 30 molecules of Aurora Kinase inhibitor class in
development stage at different levels. With increase in cancer patients the market for Aurora Kinase Inhibitor market
is set to increase.
Some of the major players in Aurora Kinase Inhibitor development market are Merck, Pfizer, Amgen, Millennium
Pharmaceuticals, Cyclacel Pharmaceuticals, Bristol Myers Squibb. Along with these, there are companies such as
Roche, Novartis, Eli Lilly, AstraZeneca, Celgene, Sanofi and GlaxoSmithKline have made their mark in oncology.
This research report analyzes this market on the basis of its market segments, major geographies, and
current market trends. Geographies analyzed under this research report include

North America

Asia Pacific

Europe

Middle East and Africa

Latin America
This report provides comprehensive analysis of

Market growth drivers

Factors limiting market growth

Current market trends

Market structure

Market projections for upcoming years
This report is a complete study of current trends in the market, industry growth drivers, and restraints. It
provides market projections for the coming years. It includes analysis of recent developments in
technology, Porter’s five force model analysis and detailed profiles of top industry players. The report also
includes a review of micro and macro factors essential for the existing market players and new entrants
along with detailed value chain analysis.
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