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3D Printing: organs &tissues

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Daniel Medeiros
Biomedical Engineering
Problem

2009: 154,324 patients waiting for organs
 27,996 patients received them (18%)

8,864 patients died waiting
 Approx. 25 people per day
Cost of surgery & follow up procedures in
2012: $300 billion
 Tissue Rejection & Immunosuppressants

3D Printing
“Sterolithography”
 Present day:

 $700 million industry
 $11 million invested in medical applications (1.6%)

Next 10 years:
 $8.9 billion industry
 $1.9 billion invested in medical applications (21%)
Typical Process for Bioprinting
Murphy, Sean V., and Anthony Atala. "3D Bioprinting of Tissues and Organs." Nat
Biotechnol Nature Biotechnology 32.8 (2014): 773-85. Web.
Design Approaches
 Mini-Tissues
 Biomimicry
 Self-Assembly
Material/Cell Selection
 Synthetic
Polymers, Natural
Polymers, Extracellular Matrix
 Differentiated
Cells & Stem Cells
 Allogenic v.s Autologous
Discussion
Need
Money
Speed/Time
Biocompatibility
Complexity
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