7th Annual Thematic Workshop of CRS Italy Chapter
Nanomedicine: pharmacokinetic challenges, targeting
and clinical outcomes
Istituto Geografico Militare
Via Cesare Battisti, Florence (Italy)
November 6th-8th, 2014
Scientific Committee: Piero Baglioni, Paolo Caliceti, Bice Conti, Maurizio D’Incalci, Giuseppe De Rosa,
Francesca Maestrelli, Pietro Matricardi, Paola Mura.
Local Organizing Committee: Debora Berti, Natascia Mennini, Marzia Cirri, Giada Casella, Costanza
Montis.
PROGRAM
Thursday afternoon
14.00-14.30
Welcome: Paola Mura, Piero Baglioni, Bice Conti, Paolo Caliceti
November 6th, 2014 – Thursday Afternoon
Chairman: Giovanni Tosi
Discussant panel: Dan Peer; Twan Lammers; Stefano Salmaso; Piero Baglioni
1st session 14.30-16.30
Stefaan DeSmedt, Dept of Pharmaceutics, Ghent University, Belgium
Exploring and struggling with biological matter to open new avenues for advanced drug
delivery
Miriam Colombo, Dept. of Biotechnologies and Biosciences-University Bicocca, Milan, Italy
Development of targeted colloidal nanoparticles for breast cancer diagnosis and treatment.
Oral poster presentation
16.30-17.00 Coffee break
2nd session 17.00-19.30 - Chairman: Pasquale Del Gaudio
David Stepensky, Dept. of Clinical Biochemistry and Pharmacology, Ben-Gurion University of the
Negev, Israel
Approaches for intracellular drug targeting using nano-drug delivery systems
Rossella Dorati, Dept. of Pharmaceutical Sciences, University of Pavia, Italy
Drug loaded composite scaffolds in bone tissue regeneration, and targeting local bacterial
infections
Kevin W. Burton, Drug Delivery Services, Pharma Polymers & Services, Evonik Health Care
Business Line
Formulation Development of Complex Parenteral products
Oral poster presentation
20.00 Welcome cocktail
November 7th, 2014 – Friday morning
Chaiman: Tommasina Coviello
Discussant panel: Stefaan De Smedt; Paolo Bigini; Barbara Ruozi, Yvonne Perrier
1st session 8.30-10.30
Dan Peer - Dept. of Cell Research & Immunology, and Dept. of Materials Science & Engineering,
Unversity of Tel Aviv University, Israel
To target or not to target? Hurdles in targeted nanomedicine for preclinical and clinical
applications
Roberta Cavalli, Dept. of Drug Science and Technology, University of Turin, Italy
Doxorubicin-loaded nanobubbles for combining shock waves and targeted chemotherapy.
Frederique Bordes Picard, Capsugel
Patient Centric Focus Design : changing the development paradigm
10.30-11.00 Coffee break
2nd session 11.00-13.00 - Chairman: Carlo Morasso
Twan Lammers, RWTH Aachen University, Germany
Passive vs active targeting
Giuseppe De Rosa, Faculty of Pharmacy - University of Naples, Italy
Self-assembling nanoparticles for drug delivery: advantages, potentialities and issues.
Oral poster presentation
November 7th, 2014 – Friday afternoon
Chairman: Andrea Cappelli
Discussant panel: Randall Mrsny; Enrico Mastrobattista; Gianfranco Pasut; Maurizio D’Incalci
1st session 14.30-16.30
Paolo Decuzzi, Methodist Hospital, Houston, USA and Director of Laboratory of Nanotechnology
for Precision Medicine, Department of Drug Discovery and Development, IIT
Discoidal Polymeric Nanoconstructs with unprecedented longevity in blood and tumor
accumulation
Mariano Licciardi, Dept. of Biological, Chemical and Pharmaceutical Technologies and Sciences,
University of Palermo - Italy
Metallic core nanocarriers for multiple cancer targeting
Oral poster presentation
16.30-17.00 Coffee break
2nd session 17.00-19.30 - Chairman: Davide Prosperi
Yvone Perrie, School of Life and Health Sciences, Aston University, UK
Is there a role for controlled release in vaccine formulation?
Roberto Santoliquido, ALFATEST
Assessment of the efficiency of encapsulation of a fluorescent drug using Nanoparticle
Tracking Analysis.
Shadi Farhangrazi, Dept. of Management, Daniels College of Business, Denver University, USA
Success by Design: What do we want the future of nanomedicine (or medicine) to look like?
20.00 Social dinner
November 8th, 2014 – Saturday Morning
Discussant panel: Moein Moghimi; David Stepensky; Paolo Decuzzi, Sancini Giulio
1st session 9.00-11.00
Chairman: Natascia Mennini
Randall Mrsny, Dept. of Pharmacy and Pharmacology, Bath University, UK
Understanding and developing the science behind oral protein and peptide delivery
Sara Nicoli, Department of Pharmacy, University of Parma, Italy
Iontophoresis as a noninvasive approach for the ocular delivery of macromolecules.
11.00-11.30 Coffee break
2nd session 11.30-13.30 - Chairman: Giuseppe Colombo
Enrico Mastrobattista – University of Utrecht – The Netherlands
Polymer and peptide-based vectors for gene delivery
Aurélie Schoubben, Dept. of Pharmaceutical Sciences, University of Perugia - Italy
Inhalation therapy for pulmonary infections
Poster awards and Concluding remarks
Anna Rita Bilia, University of Florence, Department of Chemistry
Moein Moghimi, University of Copenhagen, Center for pharmaceutical nanotechnology and
toxicology