CEINGE-Biotecnologie avanzate Ten Years of Research in the Biomedical Sciences 28-30 April 2014, Naples, Italy TENTATIVE PROGRAM Scientific Committee Filiberto Cimino Francesco Salvatore Scientific Secretariat Scientific Communication Via Quagliariello 29 - 80131 Napoli Tel. +39 081 2296460 - +39 081 2296037 Fax +39 081 0072045 [email protected] Press Officer for the Event Roberto Conte Tel. +39 380 712 3104 Venues 28, 29 & 30 April 2014 Hotel Excelsior Via Partenope 48 Naples, Italy 30 April 2014 Aula Magna Storica Università di Napoli “Federico II” Corso Umberto I CEINGE’S TENTH ANNIVERSARY 2004-2014 Monday 28 April 2014 Venue: Hotel Excelsior, Via Partenope 48 14.00-18.00 OPENING SESSION (TENTATIVE PROGRAM) Welcome Addresses and Introductory Talks Chairman: Antonello Perillo, Caporedattore Centrale Rai Napoli Stefania Giannini, Italian Minister of Education, University and Research Beatrice Lorenzin, Italian Minister of Health Stefano Caldoro, President of the Campania Region Luigi de Magistris, Mayor of Naples Massimo Marrelli, Rector of the University of Naples “Federico II” Antonio Pentangelo, President of the Province of Naples Maurizio Maddaloni, President of the Naples Chamber of Commerce Luigi Nicolais, President of the Italian National Research Council (CNR) Guido Trombetti, Vice-President of the Regional Government and Councillor for University and Scientific Research Introduction to the Meeting Francesco Ramirez, Chair of the CEINGE International Scientific Advisory/Evaluation Committee Francesco Salvatore, CEINGE, and University of Naples “Federico II” Round Table “Relationship and Integration Between Advanced Training and Research in the Biomedical Sciences” Joint session: University of Naples “Federico II” and CEINGE-Biotecnologie avanzate Chairs: Massimo Marrelli, Gaetano Manfredi, Stefano Paleari (CRUI President) and Francesco Salvatore Participants: Rectors of Italian Universities Massimo Mario Augello, Pisa Giovanni Puglisi, Milano IULM and & Enna Loris Borghi, Parma* KORE Lucio D'Alessandro, Napoli Suor Orsola Aldo Quattrone, Catanzaro “Magna Graecia”* Benincasa Claudio Quintano, Napoli Parthenope Filippo de Rossi, Sannio Maurizio Ricci, Foggia Carmine Di Ilio, Chieti-Pescara* Francesco Rossi, Napoli SUN* Luigi Frati, Roma La Sapienza* Nicola Sartor, Verona Roberto Lagalla, Palermo* Aurelio Tommasetti, Salerno Cristina Messa, Milano-Bicocca* Gianluca Vago, Milano Giuseppe Novelli, Roma Tor Vergata* Lida Viganoni, Napoli L'Orientale Gianmaria Palmieri, Molise Sergio Pecorelli, Brescia* *Scheduled presentations The Opening Session will be in Italian with simultaneous translation in English CEINGE’S TENTH ANNIVERSARY 2004-2014 Tuesday 29 April 2014 Venue: Hotel Excelsior, Via Partenope 48 ADVANCES AND PERSPECTIVES IN THE LIFE SCIENCES AS APPLIED TO THE BIOMEDICAL SCIENCES Presentations by CEINGE’s ISAEC members, Directors of Scientific Institutes in Italy and abroad, CEINGE PIs 8.30-12.30 Scientific Session RNA metabolism in neurodegenerative diseases. Pathogenic mechanisms and innovative therapies Francisco Baralle, General Director, International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste Therapeutic cancer vaccines: progress and challenges Gennaro Ciliberto, Scientific Director, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", Naples Basic and translational research hand in hand at TIGEM Andrea Ballabio, Scientific Director, Telethon Institute of Genetics and Medicine (TIGEM), Naples The ubiquitin proteolytic system. From basic mechanisms thru human diseases and on to drug development Aaron Ciechanover, Nobel Laureate in Chemistry, Technion-Israel Institute of Technology, Haifa, Israel Nanomedicine and transport oncophysics Mauro Ferrari, President and CEO, Houston Methodist Research Institute, TX, USA Learning from large scale genome projects Roderic Guigò, Centre for Genomic Regulation (CRG), Barcelona, Spain An emerging view of the chromatin landscape through protein-lncRNA interactions Martin Walsh, Icahn School of Medicine at Mount Sinai, New York, NY, USA Contribution of DNA analysis to some historic cases and to the Cosmopolitan Chicken project Jean-Jacques Cassiman, Catholic University of Leuven, Belgium 13.00-14.00 Lunch break 14.00-18.00 Scientific Session Mitochondrial Ca2+ handling, a life and death signal Tullio Pozzan, Director, Dept of Biomedical Sciences, CNR, Rome Non-coding DNA: diagnostic role in human inherited diseases? Giuseppe Castaldo, CEINGE-Biotecnologie Avanzate, Naples Transcription factor regulation of pluripotency Antonio Simeone, Director, Institute of Genetics and Biophysics (IGB), CNR, Naples Causes and consequences of microRNA dysregulation in cancer Carlo M. Croce, Chair, College of Medicine, Ohio State University, Columbus, OH, USA Is tissue biology ready for prime time? Francesco Ramirez, Mount Sinai School of Medicine, New York, NY, USA New players in embryonic stem cell differentiation Tommaso Russo, CEINGE-Biotecnologie Avanzate, Naples The transcription factor REST and neurosecretion: from basic research to human diseases Jacopo Meldolesi, San Raffaele Hospital, Milan From bacteria to schizophrenia Alessandro Usiello, CEINGE-Biotecnologie Avanzate, Naples A coffee point will be available throughout the day CEINGE’S TENTH ANNIVERSARY 2004-2014 Wednesday 30 April 2014 Venue: Hotel Excelsior, Via Partenope 48 08.30-11.00 Scientific Session (continuation of the presentations of the previous day) Molecular machines regulating intracellular membrane traffic: from fundamental to applied science Daniela Corda, Director, Institute of Protein Biochemistry (IBP), CNR, Naples Somatic mutations, somatic mutation rate and cancer Lucio Luzzatto, Scientific Director, Istituto Toscano Tumori, Florence The stem cell compartment in the mammary gland: connecting cell fate to tumor suppression Pier Paolo Di Fiore, FIRC Institute of Molecular Oncology Foundation (IFOM), Milan Next generation sequencing from bench to bedside Maurizio Ferrari, San Raffaele Hospital, Milan Development of innovative therapies: gene therapy and beyond Lucio Pastore, CEINGE-Biotecnologie Avanzate, Naples Conferment of an “Honorary PhD Degree” in Biotechnological Sciences upon Dr. Mauro Ferrari (Houston, USA) Venue: “Aula Magna Storica”, University of Naples “Federico II” Corso Umberto I, Naples