THE 4th INTERNATIONAL SYMPOSIUM ON MOLECULAR TECHNOLOGY (Biotechnology in Progress) Drug Development and Therapeutics October 14-16, 2014 Tehran, Iran 4th INTERNATIONAL SYMPOSIUM ON MOLECULAR TECHNOLOGY (Biotechnology In Progress) Drug Development and Therapeutics October 14-16, 2014 Tehran, Iran Program Book http://icda.ir/ 4th INTERNATIONAL SYMPOSIUM ON MOLECULAR TECHNOLOGY (Biotechnology in Progress) Drug Development and Therapeutics October 14-16, 2014; Tehran, Iran Tuesday 14th October 2014 Time Session, Topic 8:00am-6:00pm Delegate Registration Chair: Nader Maghsoudi (Iran) 8:30-9:30 Introduction talk: Nader Maghsoudi (Symposium scientific director and chair of ICDA) Welcome note: Ali Asghar Peivandi (President of Shahid Beheshti Univ. of Medical Sciences) Key note: Masoumeh Jorjani (Chair of Symposium and the dean of the Faculty of Medicine, SBMU) Opening talk: Mostafa Ghanei (Head of Iran's Pasteur Institute and Biotechnology Development Council) Exhibition Opening: Mostafa Ghanei 9:30-10:15 Richard Lockshin (USA): From basic science to drug development 10:15-11:30 Zahra Zakeri (USA): Considering gender in therapeutics and drug development 11:30-12:00 Jamshid Davoodi (Iran): BIR-3 domain of X-Linked Inhibitor of Apoptosis Protein (XAIP) as a preferred target for SMAC based anticancer agents 12:00-1:30 Pray and lunch break - Poster presentation Chairs: Zahra Zakeri (USA), Jalal Pourahmad (Iran) 1:30-2:15 Mehmet Ozturk (Turkey): Novel monoclonal antibodies against Her-2 as therapeutic alternatives to Trastuzumab in breast cancer 2:15-3:00 Saghi Ghaffari (USA): Stem cells, oxygen metabolism and disorders of aging: Targeting an interactive network for therapeutics 3:00-3:30 Hamid Reza Rezvani (France): XPC deficiency-induced tumoral transformation and premature onset of aging can be mitigated by inhibition of NADPH oxidase activity 1 http://icda.ir/ 4th INTERNATIONAL SYMPOSIUM ON MOLECULAR TECHNOLOGY (Biotechnology in Progress) Drug Development and Therapeutics October 14-16, 2014; Tehran, Iran 3:30-4:00 Saadi Khochbin (France): Cell identity loss in cancer: a source of new biomarkers and therapeutic targets 4:00-4:30 Mossa Gardaneh (Iran): GDNF-RET signaling inhibits trastuzumabinduced apoptosis and induces cell growth in breast cancer 4:30-5:00 Razieh Yazdanparast (Iran): The potentials of imaging mass spectrometry (ims), a molecular structure – based new disease diagnostic and prognostic tool, in cell signaling studies 5:00-6:00 Poster presentation Wednesday 15th October 2014 Time Session, Topic Chairs: Fereshteh Motamedi (Iran), Mohammad Javan (Iran) 9:00-9:45 Marie Hardwick (USA): Cell death screen in yeast uncovers human disease genes and potential therapies 9:45-10:30 Peter Vandenabeele (Belgium): Regulation and execution of necroptosis: molecular mechanisms in vitro and in vivo 10:30-11:15 Nazanine Modjtahedi (France): A strategy for the correction of the mitochondrial respiratory chain complex i deficiency 11:15-12:00 Jerry Edward Chipuk (USA): Life and death decisions involving mitochondria and their manipulation for therapy 12:00-1:30 pm Pray and lunch break - Poster presentation Chairs: Jamshid Davoodi (Iran), Ahmad Zavaran (Iran) 1:30-2:15 Raymond Birge (USA): Phosphatidylserine signaling and the clearance of apoptotic cells 2:15-3:00 Mojgan Djavaheri-Mergny (France): Autophagy, cell death and differentiation in leukemia cells 3:00-3:30 Maryam Mehrpour (France): Targeting autophagy, an Achille’s heel of cancer stem cells 2 http://icda.ir/ 4th INTERNATIONAL SYMPOSIUM ON MOLECULAR TECHNOLOGY (Biotechnology in Progress) Drug Development and Therapeutics October 14-16, 2014; Tehran, Iran 3:30-4:00 Jalal Pourahmad (Iran): Dracocephalum: novel anticancer plant acting on liver cancer cell mitochondria 4:00-5:00 The election of the Board of Directors of “Iranian Cell Death Association; ICDA” 5:00-6:00 Poster presentation Turesday 16th October 2014 Time Session, Topic Chairs: Masoumeh Jorjani (Iran), Ali Mohammad Sharifi (Iran) 9:00-9:45 Ali Jazirehi (USA): Manipulation of apoptotic machinery for sensitization of human melanomas to immune effector cells through TRAIL/Apo2L pathway 9:45-10:15 Mahvash Tavassoli (UK): Improving management of head and neck cancer with predictive biomarkers and targeted therapy 10:15-11:00 Shida Yousefi (Switzerland): Molecular mechanisms of extracellular DNA trap formation 11:00-11:30 Reginald Halaby (USA): Triptolide exerts its anticancer effects via a lysosomal-mediated mechanism: implications for treating apoptosisresistant breast cancers. 11:30-12:00 Closing remarks and end of the meeting 3 http://icda.ir/ 4th INTERNATIONAL SYMPOSIUM ON MOLECULAR TECHNOLOGY (Biotechnology in Progress) Drug Development and Therapeutics October 14-16, 2014; Tehran, Iran Posters; Tuseday 14th October 2014 Row Code Presenting Author Abstract Title Cell Death in Health and Disease 1 P1-I1-1001 2 P1-I1-1002 3 P1-I1-1003 4 P1-I1-1004 5 P1-I1-1005 6 P1-I1-1006 7 P1-I1-1007 8 P1-I1-1008 9 P1-I1-1009 10 P1-I1-1010 11 P1-I1-1011 12 P1-I1-1012 13 P1-I1-1013 14 P1-I1-1014 4 Motahare Koohsari Protective effects of propofol against methamphetamine-induced cardiotoxicity Repositioning FDA-approved drugs for modulation Farnaz Barneh of cell-death; perspectives from systems pharmacology Inhibitory effect of telmisartan on high glucoseHabib Eslami induced apoptosis in PC12 cells: role of NADPH oxidase Histopathological study of hepatic fibrosis in Zahra experimental obstructive cholestatic rats treated with Mohammadian folic acid supplementation The effects of different doses of folic acid on the Zahra expression of TGF-β1 and α-SMA in liver fibrosis Mohammadian induced by bile duct ligation in rats Study of oxidative stress and induction of apoptosis Laya in K562 cell treated with the active compound from Khoshtabiat dithio-carbamate family Cytotoxic and apoptotic activity of different extracts Zahra Tayaraniof Artemisia biennis Willd. on K562 and HL-60 cell Najaran lines Zahra Tayarani- Cytotoxic and apoptotic activity of Vincetoxicum Najaran pumilum on HL-60 and K562 leukemic cell lines Investigation of cell death pathways in T47D cell Fereshte Taghiee line in concurrent treatment by quercetin and tamoxifen The N-termianl domain of RUNX3 protein can Narges induce cell death in an impaired TGF-β pathway Rahmanian context Apoptotic Effects of ICD-85 on A549 Cancer Cell Sholeh Javadi Line&HEK293Normal cell line Sadegh Data integration framework on COPD provides a Azimzadeh comprehensive view on apoptosis blockage Jamalkandi The interplay between oxidative stress and Akram trastuzumab-induced cell death in breast SKBR3 cell Sadeghirizi line Mohsen Engineered hA-MSC, capable of simultaneous Khorashadi secretion of cell penetrable Smac7-GFP-Tatm and http://icda.ir/ 4th INTERNATIONAL SYMPOSIUM ON MOLECULAR TECHNOLOGY (Biotechnology in Progress) Drug Development and Therapeutics October 14-16, 2014; Tehran, Iran Zadeh 15 P1-I1-1015 Sanaz Naderi 16 P1-I1-1016 Mahbobeh Kheirkhah Moghadam Miyankoli 17 P1-I1-1017 Hamid Momeni 18 P1-I1-1018 Najmeh Ajili 19 P1-I1-1019 Habib Ghaznavi 20 P1-I1-1020 Rezvan Najafi 21 P1-I1-1021 Iman Barekati 22 P1-I1-1022 Lila Oudbor terimeric ILZ-TRAIL, significantly promotes apoptosis of breast cancer cells Thermal inactivation study of miniapoptosome complex and its components Study of caspase-9 & procaspase-9 stability in miniapoptosome complex with fluorescence spectroscopy Reza Protective effect of curcumin and curcuma longa extract on apoptosis of motor neurons in cultured spinal cord slices of adult mouse Activation of caspase-9 and procaspase-9 by miniapoptosome Neuroprotective effects of yttrium oxide nanoparticles on High Glucose induced oxidative stress and apoptosis in PC12 cells Neuroprotective effects of Cerium oxide nanoparticles on High Glucose induced oxidative stress and apoptosis in PC12 cells Comparison of Cellular and Molecular Cytotoxic Mechanisms of Cochlodinium polykrikoides in Isolated Trout and Rat Hepatocytes Stevia induced alteration of cell death related gene expression in pancreatic tissue of diabetic rats Targeted Molecular Therapy in Neoplasia 23 P1-I5-1001 Fatemeh Mosaffa 24 P1-I5-1002 Seyed Mohammad Taghdisi 25 P1-I5-1003 26 P1-I5-1004 27 P1-I5-1005 28 P1-I5-1006 29 P1-I5-1007 5 Investigation of the role of Protein Kinase B (AKT) in determining the response to cytotoxic effects of TNF-α in MCF-7 breast cancer cells and their drugresistant derivatives (MCF-7/MX) Targeted delivery of Epirubicin to cancer cells by PEGylated A10 aptamer Synergistic effects of anti-stress drug of propranolol and anti-inflammatory drug of celecoxib in K562 cell line: an in vitro study Growth inhibition and apoptosis induction by a Majid Spiroquinazolinones derivative in chronic myeloid Ghasemian leukemia cell line k562 Induction of differentiation and apoptosis in K562 Roghayeh leukemia cells by a new compound from Rahimi dyhidropyrano[c]chromene Roya Kishani Insulin-like growth factor 1 gene polymorphism and Farahani risk of gastric cancer Roya Kishani Clinical advantages of BRAF mutation test in Sepide Bastani http://icda.ir/ 4th INTERNATIONAL SYMPOSIUM ON MOLECULAR TECHNOLOGY (Biotechnology in Progress) Drug Development and Therapeutics October 14-16, 2014; Tehran, Iran Farahani 30 P1-I5-1008 31 P1-I5-1009 32 P1-I5-1010 33 P1-I5-1011 34 P1-I5-1012 35 P1-I5-1013 36 P1-I5-1014 37 P1-I5-1015 38 P1-I5-1016 39 P1-I5-1017 40 P1-I5-1018 41 P1-I5-1019 42 P1-I5-1020 43 P1-I5-1021 44 P1-I5-1022 45 P1-I5-1023 6 colorectal cancer Synergistic effects of anti-inflammatory drugs, ibuprofen and indomethacin in human chronic Afsaneh Bapari myelocytic leukemia K562 cell line: an in vitro study Modulation of AMPK α and Foxo3a signaling Elahe Mirzarazi elements in MPA-triggered erythroid differentiation Dahaghi of chronic myelogenous leukemia cells Superoxide dismutase and glutathione are pivotal Elahe Mirzarazi antioxidant targets in MPA-triggered erythroid Dahaghi differentiation of K562 cells Antioxidant and cytotoxic effects of metanolic and Shadi Shahsar ethanolic extracts of Trifolium caucasicum on HepG2 cell line Pectic acid (PI) leads the induction of apoptosis in Sima Paya pituitary tumor cells (GH3/B6) by changing level of Bcl-2 and caspase 3 Combination effect of Doxorubicin and modified Shabnam citrus pectin (MCP) induces apoptosis in breast Esfandiarpour cancer cell line (4T1) via NO release Cellular oxidative damages and apoptosis induced Sakineh Asghari by an active compound from pyrano-pyridine Marjanlou derivatives in K562 leukemia cell Growth inhibition and apoptosis-inducing effects of Motahareh Scutellaria pinnatifida A.Ham on human cancer cell Boozari lines Safiyeh GTP depletion enhances the anti-cancer activity of Aghazadeh Trastuzumab in SkBr3 breast cancer cell line Acacetin acting directly and selectively on Ahmad Salimi mitochondria isolated from B lymphocytes in chronic lymphocytic leukemia patients Zahra Evaluation of the apoptosis inducing activity of Amirghofran Foeniculum vulgare on human leukemia cell lines Fatemeh Ibuprofen reduces Sox2 gene expression in gastric Mahmoodi cancer cells (AGS) Fatemeh Decreased angiogenesis in gastric cancer stem cells Mahmoodi by treatment with ibuprofen Effects of the derivative from Pyrano [3, 2-c] Mohammad pyridine family on proliferation and Apoptosis Rahnamay Induction MCF-7 human cancer cells Mohammad Investigating the possible role of Berberine on the Amir Mishan metastatic behavior of esophageal cancer cells Vida Investigating the feasibility of c-MYC inhibition by Pourteimoor miRNA as a new pharmacological approach against http://icda.ir/ 4th INTERNATIONAL SYMPOSIUM ON MOLECULAR TECHNOLOGY (Biotechnology in Progress) Drug Development and Therapeutics October 14-16, 2014; Tehran, Iran 46 P1-I5-1024 47 P1-I5-1025 cancer Sadat Expression analysis of SYK gene in retinoblastoma tumor tissues compared to normal retina Beta lactam structured Cox-2 inhibitors: Novel anti Nahal Pirahmadi cancer compounds on B lymphocytes Mitochondria in Acute Lymphocytic Leukemia (ALL) Patients Fatemeh Rashidi Targeted Molecular Therapy in Viral disorders 48 P1-I6-1001 49 P1-I6-1002 Naghmeh Poorinmohammad Naghmeh Poorinmohammad Computer-aided modification of a potent anti-HIV1 peptide derived from HIV-1 P24 protein Mechanism of action of anti-HIV-1 peptides is closely related to the sequence-order information Targeted Molecular Therapy in Neurodegenerative diseases 50 P1-I7-1001 51 P1-I7-1002 52 P1-I7-1003 53 P1-I7-1004 54 P1-I7-1005 55 P1-I7-1006 56 P1-I7-1007 57 P1-I7-1008 58 P1-I7-1009 59 P1-I7-1010 60 P1-I7-1011 7 Alleviation of neurodegenerative diseases and Leyla Shahidi improvement of human life span through a Bonjour prospective new treatment Protective effect of resveratrol against paraquatinduced oxidative damage in isolated brain Faeze Alidoust mitochondria; a new therapeutic agent in Parkinson’s disease Nanochelating technology introduces a new efficient Mohammad structure with neuroprotective activity in animal Hasan Nazaran model of multiple sclerosis NDc, the first nanocomplex of the new generation of Mohammad anti-neurodegeneration agents, protects PC12 cells Hasan Nazaran against MPP+-induced cytotoxicity Farshad β-Amyloid inhibits integrated mitochondrial key Arsalandeh enzyme activities in rat hippocampus Farshad Evaluation of the neuroprotective effect of Arsalandeh salvigenin on memory of Aβ-injected rats Collaboration of Geldanamycin-activated P70S6K and Hsp70 reverses memory deficit induced by βNayereh Zare amyloid associated with decrease of apoptotic factors A Pentapeptide (GLMVG) drug inhibit Aβ Vahid Khandan aggregation; An in silico study for treatment of Alzheimer’s disease 3-methyladenine exacerbates recognition memory Fatemeh deficits in amyloid beta injected rats by attenuation Shaerzadeh of mitochondrial biogenesis regulators Molecular assessment in relapsing-remitting Mansour multiple sclerosis (RRMS) patients: future Shajarian therapeutic approach for neurodegenerative diseases Mehdi Mitochondrial dysfunction plays a key role in Kouhnavard Multiple Sclerosis induced by cuprizone in mice http://icda.ir/ 4th INTERNATIONAL SYMPOSIUM ON MOLECULAR TECHNOLOGY (Biotechnology in Progress) Drug Development and Therapeutics October 14-16, 2014; Tehran, Iran 61 P1-I7-1012 Elnaz Bakhtiari Protective effect of Maviz (a specific kind of dried grape) against beta amyloid peptide induced– memory impairment: role of non-polyphenolic compounds Posters; Wedenesday 15th October 2014 Row Code Presenting Author Abstract Title Mitochondria in Cell Death 1 P2-I2-1001 Zeinab VafaeiPour 2 P2-I2-1002 Monire Jahani 3 P2-I2-1003 Narges Vaezi 4 P2-I2-1004 Fatemeh Shaki 5 P2-I2-1005 Enayatollah Seydi 6 P2-I2-1006 Solmaz Khalife Inhibition of mitochondrial oxidative damage by Nanoceria leads to protection against Streptozotocin induced-neroutoxicity Nanoceria prevented Streptozotocin inducedhepatotoxicity via mitochondrial toxicity inhibition Nanoceria diminished Streptozotocin inducedcardiotoxicity by protection against mitochondrial toxicity Propofol attenuated methamphetamine-induced neurotoxicity via mitochondrial protection Apigenin induces mitochondria mediated apoptosis in hepatocellular carcinoma cells Nrf2 silencing induced apoptosis and changed ETC’s enzymes activity in the male Wistar rat’s brain Signalin Pathways in Drug Discovery 7 P2-I3-1001 8 P2-I3-1002 9 P2-I3-1003 10 P2-I3-1004 11 P2-I3-1005 12 P2-I3-1006 13 P2-I3-1007 8 Synthesis and biological evaluation of novel 1, 2Farzin Hadizadeh dihydropyridine-3-carbonitrile derivatives as PIM-1 kinase inhibitor agents Reduction of acrylamide – induced neurotoxicity in Soghra Mehri cerebellum tissue following administration of crocin in wistar rat Effects of intraperitoneal thymoquinone on chronic Bahareh Amin neuropathic pain in rats Samira In vitro survey of aqueous extract of Trigonella Dodangeh foenum-graecum on Acanthamoeba trophozoites Protective effects of crocin on malathion induced Bibi Marjan depressant-like behavior in subacute exposure: Razavi Involvement of BDNF neurotrophic factor Proteomics screening of molecular targets of Maryam Granulocyte Colony Stimulating Factor in the mouse Ghorbani brain and PC12 cell line Soraya Menadione potentiates antigrowth effect of http://icda.ir/ 4th INTERNATIONAL SYMPOSIUM ON MOLECULAR TECHNOLOGY (Biotechnology in Progress) Drug Development and Therapeutics October 14-16, 2014; Tehran, Iran Sajadimajd 14 P2-I3-1008 Parinaz Nasri 15 P2-I3-1009 Ramin Karimi Sales 16 P2-I3-1010 Razieh Ghodsi 17 P2-I3-1011 Azadeh Sarfallah 18 P2-I3-1012 Farnosh Shemirani 19 P2-I3-1013 Farnosh Shemirani 20 P2-I3-1014 Sareh Sangy 21 P2-I3-1015 Babak Abdi 22 P2-I3-1016 Mahvash Farajzadeh 23 P2-I3-1017 Mandana Ahmadi 24 P2-I3-1018 Masoumeh Babaei Khalili 25 P2-I3-1019 Azam Roohi 26 P2-I3-1020 27 P2-I3-1021 28 P2-I3-1022 Nasrin Shojaei 29 P2-I3-1023 Mona Maleki 30 P2-I3-1024 Samaneh Rouhi 31 P2-I3-1025 Shima Sardab 9 Shokoofeh Siroosi Forouzan Sadeghimahalli Trastuzumab via ROS modulation in SKBr3 cells Study of anti-oxidative and anti-cancer effects of Rutin and Tamoxifen in the treatments of T-47D cell line The new nanochelating based nano complex, Alz-C, decreases the cleaved form of caspase-3: comparison with memanitine Design, Synthesis and Biological Evaluation of Novel Imidazolylmethylquinoline Derivatives as Selective COX-2 Inhibitors Silibinin inhibits mTOR activation following high glucose treatment in human mesenchymal stem cells The ameliorative impact of resveratrol on AGEinduced oxidative stress and the level of soluble RAGE in a hyperglycemia model system AGE-induced oxidative stress can modulate the level of soluble receptor for AGE (sRAGE) in K562 cells The effect of Curcumin longa on the viability and growth of human mesenchymal stem cells Structural and functional study of E.coli, Erwinia chrysanthemi and human L-asparaginase using bioinformatic tools Cytotoxic activities and proposed mode of binding of a derivative of dihydropyranochromenes Anti-bacterial activity of Scrophularia striata against resistant Pseudomonas aeruginosa with gyrA gene obtained from Isfahan hospitals A transitional cell cycle arrest induced by H2O2 in NIH3T3 fibroblasts Glucose affects viability and cell cycle of human mesenchymal stem cells treated with hydrogen peroxide, rapamycin and metformin GABA-transporter GAT-1 inhibition attenuates the expression of morphine antinociceptive tolerance Chronic psychological stress increases pancreatic glucose transporter 2 levels in male young adult rats Downregulation of Wnt signaling pathway as a hallmark in the resistant conventional chemotherapy Metfomin modulates TCA enzymes activity in the hippocampus of restraint stress-induced rats Molecular detection of extended-spectrum betalactamases OXA type in human blood samples using OXA-1 and OXA-2 Study of the cellular effects of concurrent treatment http://icda.ir/ 4th INTERNATIONAL SYMPOSIUM ON MOLECULAR TECHNOLOGY (Biotechnology in Progress) Drug Development and Therapeutics October 14-16, 2014; Tehran, Iran 32 P2-I3-1026 33 P2-I3-1027 34 P2-I3-1028 35 P2-I3-1029 36 P2-I3-1030 of T-47D cells by Quercetin and Rutin A study of antioxidant properties of honey sample in Sedighe Dehghan five different geographical region of Iran Protective effect of Yttrium Oxide Nanoparticle on Saeed Mehrzadi Degeneration of Dorsal Root Ganglion Neurons in Experimental Diabetic Neuropathy Protective effect of Cerium Oxide Nanoparticle on Saeed Mehrzadi Degeneration of Dorsal Root Ganglion Neurons in Experimental Diabetic Neuropathy Protective effect of lithium against High glucoseAzade induced neurotoxicity in PC12 cells through the Aminzadeh ROS mediated JNK, P38 MAPKs and mitochondrial apoptotic pathway Study of impaired pathway in adipose-derived Azade mesenchymal stem cell isolated from diabetic rats: Aminzadeh Role of apoptosis Concept Approaches to Gene Therapy 37 P2-I4-1001 Ali Salimi 38 P2-I4-1002 Zahra Akbari 39 P2-I4-1003 40 P2-I4-1004 41 P2-I4-1005 Maryam Hashemi 42 P2-I4-1006 Ali Sharafi 43 P2-I4-1007 Ali Sharafi 44 P2-I4-1008 Ali Sharafi 45 P2-I4-1009 Shima Ghaedizadeh 46 P2-I4-1010 47 P2-I4-1011 10 Malihe Mohseni Lavi Roya Kishani Farahani Shima Ghaedizadeh Samaneh Naderi Cloning and over-expression of recombinant vascular endothelial growth factor (VEGF- 165) Investigatin of association between Exonuclease 1 C723R polymorphism and genetic susceptibility to CRC in the Iranian population; a case – control study Study of Survivin expression in MCF- cells treated with the active derivative from quinazolin family Identification of large deletion in APC gene in Familial Adenomatous Polyposis patients Effect of PEGylation using an alkyl chain as linker on gene delivery efficiency of polypropyleneimine denderimer Plant tissue culture platform for producing apigenin in Cosmos bipinnatus Artemisinin production by transient over expression of sesquiterpene cyclase (SQC) gene in Artemisia annua L. Study of the antioxidant and antibacterial activities of methanol, dichloromethane, and hexane extracts of aerial parts of Cyperus longos Protein engineering of Renilla Luciferase using computer-aided techniques: enhancement of the enzyme applicability for in vivo gene therapy monitoring In silico modification of Renilla luciferase in terms of activity and stability Cytoplasmic expression, optimization and catalytic http://icda.ir/ 4th INTERNATIONAL SYMPOSIUM ON MOLECULAR TECHNOLOGY (Biotechnology in Progress) Drug Development and Therapeutics October 14-16, 2014; Tehran, Iran 48 P2-I4-1012 49 P2-I4-1013 50 P2-I4-1014 51 P2-I4-1015 52 P2-I4-1016 53 P2-I4-1017 54 P2-I4-1018 55 P2-I4-1019 56 P2-I4-1020 11 activity evaluation of recombinant mature lysostaphin as an anti-staphylococcal therapeutic in Escherichia coli Protection of dopaminergic neurons against 6-OHDA Ehsan Gharib toxicity by overexpression of neurotrophic factor GDNF and anti-oxidant enzyme GPX-1 Development and evaluation of a PCR-RFLP method Hamideh Tayefi for IL-17 single nucleotide polymorphisms (rs763780, rs2397084) genotyping Correlation between Irs-1 gene expression level and Elham Tafsiri down-regulation of miR-126 and miR-128 in nonsmall cell lung cancer patients Make use of personalized medicine: silencing p53 Farzaneh Iravani rather than augmentation it Site Directed Saturation Studies reveled a Faraj Allah thermostable luciferase for Biomedical Applications: Salehi A Bioinformatics Study Faraj Allah Deciphering antigenic and secretion sequences Salehi on Super renilla luciferase (SU-Rluc) Shikonin induces cell death more efficiently in Zahra estrogen receptor (ER) positive breast cancer cells Shahsavari compared to ER negative cells Study of heat shock genes 90 and 70 inhibition using Behrang Alani RNAi technology on Nrf2 activation pathways in neural like dopaminergic differentiated cells Cloning of Urate oxidase from Bacillus subtilis Shirin Ebrahimi subsp. Subtilis http://icda.ir/
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