EpCAM stands for epithelial cell adhesion molecule which is a cell surface protein (antigen) and is highly expressed in major cancer types such as breast, prostate, colon, ovarian, gastric, lung and pancreatic cancer. It is thus considered as a well established marker for cancer of epithelial origin and an ideal therapeutic target. It is not only limited to epithelial carcinomas but can also be expressed in various other epithelial tissues, progenitor and stem cells. EpCAM is not found in non-epithelial cells or in cancer without epithelial origin. EpCAM plays significant role during cell adhesion, proliferation, cell signaling, migration and differentiation. Over expression of EpCAM has been shown to promote the proliferation in primary breast carcinomas (PBCs) and other cancer types. Browse Full Report with TOC @ http://www.transparencymarketresearch.com/epcam-antagonists-market.html
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