Mehmet Odabaşı, 2014 CURRICULUM VITAE Mehmet ODABAŞI, Ph.D. Born:01.01.1970 Aksaray Universtity, Faculty of Arts and Sci. Chemistry Dept. Biochemistry Div. 68100 Aksaray/TURKIYE E-mail: [email protected] Phone: +90(382) 288 2138 Education Hacettepe Univestity, Faculty of Science, Chemistry Dept. Ankara/Turkiye Ph.D. in Biochemisry, 2005 Dissertation: Molecularly Imprinted Polymer for Separation of Proteins (Advisor: Prof. Dr. Adil Denizli) Hacettepe Univestity, Faculty of Science, Chemistry Dept. Ankara/Turkiye M.Sc. in Biochemisry, June 2000 Dissertation: DNA Carrying Magnetic Bioaffinity Sorbents for Sistemic Lupus Erythematosus Disease. (Advisor: Prof. Dr. Adil Denizli) Employment History 1994-1997 Research Assistance at Kafkas University, Kars/Turkiye 1997-2005 Research Assistance at Hacettepe University, Ankara/Turkiye 2005-2007 Dr. Research Assistance at Kafkas University, Kars/Turkiye 2007-2012 Assist. Prof. at Aksaray University, Aksaray/Turkiye 2012- Assoc. Prof. at Aksaray University, Aksaray/Turkiye Research Area 1. Polymer Technology: Production of polymers and polymeric biomaterials with various shapes (beads, membranes, cryogels) having different bulk and surface properties, modification of their surfaces by various methods and their medical and biological applications. 2. Biochemistry: Removal of toxic substances (pathogenic antibodies, metal ions such as iron and cadmium etc.) from human plasma. Enzyme immobilization. 3. Chromatographic Techniques: Preparation of polymeric biospecific sorbents and their use for the purification of enzymes and proteins (Bioaffinity Chromatography, Dye Affinity Chromatography, Immobilised Metal Affinity Chromatography, Molecular Imprinting) Courses and Schools Participated 1. "Biosensors", Biochemistry Undergraduate Summer School, 20-26 June 1999, Kusadasi, Aydın, Turkey. 2. "Basic and Modern Techniques in Biochemistry" Biochemistry Undergraduate Summer School, 27 August-3 September, Kuşadası, Aydın, Turkey. 1 Mehmet Odabaşı, 2014 3. “Chromatographic Techniques and Their Industrial Applications”, November, 2001, Turkish Scientific and Technical Research Council–Bursa Test and Analysis Laboratory, Bursa, Turkey. 4. “Protein Chromatoraphy and New Generation Polymeric systems” Biochemistry Undergraduate Summer School, 5-7 July 2007, As Lecturer, Atatürk University, Chemistry Dept., Erzurum. 5. “The Reguation of Metabolism end Metabolism Disorders” Biochemistry Undergraduate Summer School, 29 June –06 July 2008 , Trabzon 6. “Afinity Chromatoraphy” Biochemistry Undergraduate Summer School, 23-25 May 2010, As Lecturer, Aksaray University, Chemistry Dept., Aksaray, Turkey. 7. “The Last Developments in Design and Applications of Biosensors” Biochemistry Undergraduate Summer School, 01-08 Sept. 2013, Gümüşlük, Bodrum, Turkey. Projects 1. Cholesterol Removal from Human Plasma by Anti-LDL antibody attached PHEMA microspheres. Hacettepe University, Project No: 01 G 008, 2002. 2. Production of Magnetic PHEMA Microspheres, DNA immobilization and removal of AntiDNA antibodies from SLE patient plasma by column system. DPT Project No: 02 K 120 290-13, 2003. 3. Preparation of bioaffinity sorbents for protein purification. Hacettepe University, Project No: 01 02 601 012. 4. The Design and preparation of molecularly imprinted polymer for protein purification. TUBITAK, TBAG-2372, 2004. 5. The Design and preparation of chlosterol imprinted polymeric membrane, TUBITAK, MAG- 105M278, 2005. 6. Preparation and Applications of Molecularly Imprinted Quartz Crystal Microbalance (QCM) Chips for Melamine Detection, TÜBİTAK, TBAG-112T561, 2012. 7. Separation of Coumarins by Subcritical Water Chromatography, TÜBİTAK, TBAG112T336, 2012. 8. Synthesis and Application of Water Soluble o-Carboxyethyl Chitosane-Imine Palladium (II), Molybdenum (0), Copper (II) Complexes, TÜBİTAK, KIBAG-113Z296 List of Scientific Publications A. Books 1. Denizli, A., Denkbaş, E.B., Yavuz, H., Akgöl, S., Odabaşı, M., Garipcan, B., Özkara, S., Biochemistry Laboratory, Hacettepe University, Faculty of Science, Department of Chemistry, Beytepe, Ankara, 2000. 2 Mehmet Odabaşı, 2014 2. Odabaşı, M. et al., Ankara 2010. Ed.:Denizli, A.; Küfrevioğlu, Ö.İ., “New Genaration Polymeric Systems and Protein Chromatogaphy”, ISBN 978-60588783-0-3, B. Research Artichles 1. Kassab, A., Yavuz, H., Odabasi, M., Denizli, A., “Human Serum Albumin Chromatography by Cibacron Blue F3GA-Derived Microporous Polyamide Hollowfiber affinity membranes”, J. Chromatogr. B. 746(2000)123-132. 2. Denkbaş, E., B., Odabaşı, M., “Chitosan Preparation and Characterization”, Journal 76(2000)1637-1643. 3. Odabaşı, M., Garipcan, B., Dede, S., and Denizli, A., “Methacryloamidohistidine in Affinity Ligands for Immobilized Metal-ion Affinity Chromatography of Human Serum Albumin” Biotechnology and Bioprocess Engineering, 2001, 6: 402-409. 4. Odabaşı, M., Denizli, A. “Polyhydroxyethylmethacrylate Based Magnetic DNAAffinity Beads for Anti-DNA Antibody Removal from SLE Patient Plasma” J. Chromatogr. B., 760(2001) 137-148. 5. Denkbaş, E., B., Odabaşı, M., Kılıçay, E., Özdemir, E., “Human Serum Albumin (HSA) Adsorption with Chitosan Microspheres ”Journal of Applied Polymer Science, 86(2002) 3035-3039. 6. Odabaşı, M., Garipcan, B. Denizli, A. “Preparation of a novel metal-chelate affinity beads for Albumin isolation from human plasma” Journal of Applied Polymer Science, 90(2003) 2840-2847. 7. Odabaşı, M., Denizli, A. “Cibacron blue F3GA-attached magnetic poly(2hydroxyethyl methacrylate) beads for human serum albumin adsorption“ Polymer International, 53 (2004) 332-338. 8. Odabaşı, M., Uzun, L. and Denizli, A., “Porous magnetic chelator support for albumin adsorption by immobilised metal affinity separation” Journal of Applied Polymer Science, Journal of Applied Polymer Science, 93 (2004) 2501-2510. 9. Uzun, L., Odabaşı, M., Arıca, Y. and Denizli, A., “Poly(styrene-hydroxyethyl methacrylate) monodisperse microspheres as specific sorbent in dye affinity adsorption of albumin” Separation Science and Technology, 39 (2004) 10, 24012418. 10. Odabaşı, M., Denizli, A. “Cibacron blue F3GA incorporated magnetic poly(2hydroxyethyl methacrylate) beads for Lysozyme Adsorption” Journal of Applied Polymer Science, 93 (2004) 719–725. 11. Yavuz, H., Odabaşı, M., Akgol,S. and Denizli, A., “Immobilized metal affinity beads for ferritin adsorption” Journal of Biomaterials Science, Polymer Edition, 16 (2005) 673-684. Microspheres and Sponces: of Applied Polymer Science, 3 Mehmet Odabaşı, 2014 12. Odabaşı, M., Özkayar, N., Özkara, S., Ünal, S. and Denizli, A. “Pathogenic antibody removal using magnetically stabilized fluidized bed” J.Chromatogr. B., 826 (2005) 50–57. 13. Odabaşı, M., Say, R. and Denizli, A.“Molecular imprinted particles for lysozyme purification “ Materials Science and Engineering: C., 27 (2007) 90-99. 14. Ergün, B., Derazshamshir, A. and Odabaşı, M.“Preparation of Fe(III)-Chelated Poly(HEMA-MAH) Cryogel for Lysozyme Adsorption” Hacettepe Journal of Biology and Chemistry, 32 (2007) 143-148. 15. Derazshamshir, A., Ergün, B., Peşist, G., Odabaşı, M. “Preparation of Zn2+Chelated Poly(HEMA-MAH) Cryogel for Affinity Purification of Chicken Egg Lysozyme”, Journal of Applied Polymer Science, 109 (2008) 2905-2913. 16. Odabaşı M., Baydemir, G., Karataş M., Derazshamshir, A., “Preparation and Characterization of Metal-Chelated poly(HEMA-MAH) monolithic Cryogels and Their Use for DNA Adsorption”, Journal of Applied Polymer Science, 116 (2010) 1306–1312. 17. Erzengin, M., Ünlü, N., Odabaşı, M., “A Novel Adsorbent for Protein Chromatography: Supermacroporous Monolithic Cryogel Embedded with Cu 2+Attached Sporopollenin Particles”, J. Chromatogr. A., 1218 (2011) 484–490. 18. Ceylan, Ş., Kalburcu, T., Gedikli, M., Odabaşı M., Application of Cu2+- attached Magnetite Nanoparticles Embedded Supermacroporous Monolithic Composite Cryogels for DNA Adsorption, Hacettepe Journal of Biology and Chemistry, 39 (2011) 163–172. 19. Odabaşı, M., “Magnetic Dye-Affinity Beads for Human Serum Albumin Purification”, Preparative Biochemistry and Biotechnology, 41 (2011) 287-304. 20. Ünlü, N., Ceylan, Ş., Erzengin, M., Odabaşı, M., “Investigation of Protein Adsorption Performance of Ni2+-Attached Diatomite Particles Embedded to Composite Monolithic Cryogels”, Journal of Separation Science, 34 (2011) 2173– 2180. 21. Baydemir, G., Odabaşı, M., “Microsphere Embedded Cryogels for Selective and Efficient Depletion of Immunoglobulin G from Human Serum" Artificial Cells, Nanomedicine, and Biotechnology, 41(2013) 319-326. 22. Ceylan, Ş., Odabaşı, M., “A Novel Adsorbent for DNA Adsorbent: Fe3+- Attached Sporopollenin Embedded Composite Cryogels” Artificial Cells, Nanomedicine and Biotechnology, 41(2013) 376-383. 23. Ceylan, Ş., Odabaşı, M., “Investigation of Lysozyme Adsorption Performance of Cu2+-Attached PHEMA Beads Embedded Cryogel Membranes” Materials Science and Engineering: C, 34 (2014) 1-8. 24. Baran, N.Y., Odabaşı, M., “Investigation of Hemoglobın Immobilization Parameters onto Cu2+-Attached Bentonite Particles Embedded Hybrid Monolithic Cryogels” Submitted to Experimental and Clinical Sciences International online journal for advances in science (EXCLI Journal). 4 Mehmet Odabaşı, 2014 C. Presentations (International) 1. Denizli, A., Kassab, A., Yavuz, H., Odabaşı, M., Akgöl, S., Pişkin, E., “Microporous Affinity Hollow Fibers for Human Serum Albumin Isolation from Human Plasma.” World Polymer Congress, IUPAC Macro 2000, 38th Macromolecular IUPAC Symposium, 9-14 July 2000, Polish Chemical Society, Center of Molecular and Macromolecular Studies, Lodz and Warsaw University of Technology, Warsaw, Poland. 2. Odabaşı, M., Denizli, A., “DNA Carrying mPHEMA Affinity Sorbent for Removal of Anti-DNA antibody from SLE Patient Plasma”, 7th International Biomedical Science and Technology Symposium (BIOMED), 25-28 September 2000, Hacettepe University, Ankara, Turkey. 3. M. Odabaşı, E.B. Denkbaş, E. Kılıçay, N. Özdemir, “HSA Adsorption with Chitosan Microspheres” 7th International Biomedical Science and Technology Symposium (BIOMED), 25-28 September 2000, Hacettepe University, Ankara, Turkey. 4. Uzun, L., Yavuz, H., Odabaşı, M., Akgöl, S., Özkara, S., Garipcan, B., Andaç, M., Denizli, A., “Poly(styrene-hydroxyethyl Methacrylate) monodisperse microspheres for high performance dye-affinity separation of albumin, “ 27th International Symposium on High Performance Liquid Phase Separations and Related Techniques” 15-19 June 2003, Nice- France. 5. Kara, A., Yavuz, H., Akgöl, S., Odabaşı, M., Uzun, L., Beşirli, N., Denizli, A., “Poly(ethylene glycol dimethacrylate-n-vinyl imidazole) beads for heavy metal removal”, Colloquium Spectroscopicum Internationale XXXIII, 7-12 September 2003, Granada-Spain. 6. Baydemir, G., Sarı, M. Odabaşı, M., and Denizli, A., “Albumin Purification in Column Sistem with Cibacron Blue F3GA-Attached Magnetic Poly(Vinil Alcohol Microbeads” 11th International Biomedical Science and Technology Symposium (BIOMED), 6-10 September 2004, Hacettepe University, Ankara, Turkey. 7. Odabaşı, M., and Denizli, A.,“Preparation of Molecularly Imprinted polymers for protein separation” 11th International Biomedical Science and Technology Symposium (BIOMED), 6-10 September 2004, Hacettepe University, Ankara, Turkey. 8. Özkayar, N., Odabaşı, M., Ünal, S., Denizli, A., “Magnetic Beads for Pathogenic Antibody Removal in Magnetically Stabilized Fludized Bed” 11th International Biomedical Science and Technology Symposium (BIOMED), 6-10 September 2004, Hacettepe University, Ankara, Turkey. 9. Ceylan, Ş., Ünlü, N, Erzengin, M., Yılmaz, N. and Odabaşı, M., “Ni2+-Attached Diatomite Particles Embedded to Composite Monolithic Cryogels for Protein Adsorption” EUROCLAY 2011 Conference, 26 June - 1 July, 2011 Antalya-Turkey. 10. Yılmaz, N. and Odabaşı, M., “Preparatin of Cu2+-Attached Bentonite Particles Embedded to Composite Monolithic Cryogels for Protein Adsorption” EUROCLAY 2011 Conference, 26 June - 1 July, 2011 Antalya-Turkey. 5 Mehmet Odabaşı, 2014 11. Odabaşı, M., Ceylan, Ş., Alkan, M.H., Acet, Ö., Yüksel, G., Öztürk, C., Altay, M.T., “A Novel Adsorbent for DNA Adsorption: Fe3+-Attached Sporopollenin Particles Embedded Composite Cryogels” Third International Conference on Multifunctional, Hybrid and Nanomaterials, 3-7 March 2013, Sorrento, Italy. 12. Alkan, M.H., Gürbüz. F., Doğru, M., Ceylan, Ş., Odabaşı, M., “A novel low-cost natural adsorbent: Pumice, for Protein Purification with Composite Monolithic Cryogels” Third International Conference on Multifunctional, Hybrid and Nanomaterials, 3-7 March 2013, Sorrento, Italy. 13. Ceylan, Ş., Acet, Ö., Yüksel, G., Öztürk, C., Altay, M.T. Odabaşı, M.,”Investigation of Lysozyme Adsorption Performance of Cu2+-Attached PHEMA Beads Embedded Cryogel Membranes” Third International Conference on Multifunctional, Hybrid and Nanomaterials, 3-7 March 2013, Sorrento, Italy. 14. Gürbüz, F., Ceylan, Ş., Odabaşı, M., “Alternative Water Treatment Method for Microcystin Removal” 9th International Conference on Toxic, Cyanobacteria, 11-16 August 2013, South Africa. 15. Kayan, B., Şener, B., Odabaşı, B., Akay, S., “New Stationary Phase for Separation of Coumarin Derivates by Using HTLC” Pittcon 2014, 2-6 March 2014 Chicago, IL, USA. 16. Kayan, B., Odabaşı, B., Akay, S., “Separation of Coumarin, Vanilin and Ethyl Vanilin by Using Subcritical Water Chromatography” Pittcon 2014, 2-6 March 2014 Chicago, IL, USA. 6
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