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Contents
Part I
Omics Approaches in Breast Cancer
1
Omics Technologies Applied in Breast Cancer Research. . . . .
Mariana Panal Cusati, Maria Herrera de la Muela,
and Ignacio Zapardiel
3
2
Omics of Hereditary Breast Cancer . . . . . . . . . . . . . . . . . . . . . .
Catherine A. Moroski-Erkul, Burak Yilmaz, Esra Gunduz,
and Mehmet Gunduz
17
3
Oncogenes and Tumor Suppressor Genes as a Biomarker
in Breast Cancer. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Eyyup Uctepe, Muradiye Acar, Esra Gunduz,
and Mehmet Gunduz
41
4
Breast Cancer Genomics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Birendra Kumar
53
5
Epigenomics of Breast Cancer . . . . . . . . . . . . . . . . . . . . . . . . . .
Kursat Oguz Yaykasli, Ertugrul Kaya, and Emine Yaykasli
105
6
Nutrigenomics in Breast Cancer. . . . . . . . . . . . . . . . . . . . . . . . .
Shailendra Dwivedi, Shailja Shukla, Apul Goel,
Praveen Sharma, Sanjay Khattri, and Kamlesh Kumar Pant
127
7
Long Noncoding RNAs in Breast Cancer: Implications
for Pathogenesis, Diagnosis, and Therapy . . . . . . . . . . . . . . . . .
Jaroslav Juráček, Robert Iliev, Marek Svoboda,
and Ondrej Slaby
8
Breast Cancer MicroRNAs: Clinical Biomarkers for
the Diagnosis and Treatment Strategies. . . . . . . . . . . . . . . . . . .
Gowhar Shafi, Tarique N. Hasan, Naveed Ahmed Syed,
Ananta Paine, Jesper Tegner, and Anjana Munshi
153
171
9
Breast Cancer Proteomics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Ida Pucci-Minafra
183
10
Metabolomics in Breast Cancer . . . . . . . . . . . . . . . . . . . . . . . . .
Maria C. Calomarde, Javier De Santiago, and Ignacio Zapardiel
211
xxi
Contents
xxii
11
Lipidomics in Breast Cancer. . . . . . . . . . . . . . . . . . . . . . . . . . . .
Alvin Kamili and Jennifer A. Byrne
225
12
Breast Cancer Stem Cells and Cellomics. . . . . . . . . . . . . . . . . .
Esin Demir, Bilge Atar, Dipali Dhawan, Debmalya Barh,
Mehmet Gunduz, and Esra Gunduz
245
13
Omics of Male Breast Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . .
Zahide Nur Unal, Gülhan Kaya, Debmalya Barh, Esra Gunduz,
and Mehmet Gunduz
265
14
Omics of Chemoresistant and Metastatic Breast Cancer. . . . .
Margarita Aguilera and Juan Antonio Marchal
277
15
Animal Models of Breast Cancer . . . . . . . . . . . . . . . . . . . . . . . .
E.A. El-Abd, A.S. Sultan, E.A. Shalaby, and F. Matalkah
297
16
In Silico Disease Models of Breast Cancer. . . . . . . . . . . . . . . . .
Anjana Munshi and Vandana Sharma
315
17
Systems Biology and Integrative Omics in Breast Cancer. . . .
Enrique Hernández-Lemus
333
Part II
18
19
20
21
22
23
Breast Cancer: Next-Generation Diagnosis, Prognosis,
and Therapy
Gynecologic Considerations for Women
with Breast Cancer. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
William R. Robinson III and Kaneez Fatima Ali
Imaging Technologies and Applications in Early
Diagnosis and Prognosis for Breast Cancer. . . . . . . . . . . . . . . .
M. Mar Gil, Marcos Cuerva, Sara Iacoponi,
Jose I. Sanchez-Mendez, and Ignacio Zapardiel
355
371
Breast Cancer Biomarkers for Risk Assessment, Screening,
Detection, Diagnosis, and Prognosis. . . . . . . . . . . . . . . . . . . . . .
Mukesh Verma and Debmalya Barh
393
Breast Circulating Tumor Cells: Potential Biomarkers
for Breast Cancer Diagnosis and Prognosis Evaluation. . . . . .
Phuc Van Pham
409
Molecular Diagnosis of Metastasizing Breast Cancer
Based Upon Liquid Biopsy . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Shailendra Dwivedi, Apul Goel, Sadashiv, Arti Verma,
Shailja Shukla, Praveen Sharma, Sanjay Khattri,
and Kamlesh Kumar Pant
Exhaled Volatile Organic Compounds as Noninvasive
Markers in Breast Cancer. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Orna Barash and Hossam Haick
425
461
Contents
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24
25
Breast Cancer Therapy–Classical Therapy, Drug Targets,
and Targeted Therapy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Eugenia Ch Yiannakopoulou
483
Pharmacogenomics–Pharmacoepigenomics of Breast
Cancer Therapy: Clinical Implications . . . . . . . . . . . . . . . . . . .
Eugenia Ch Yiannakopoulou and Debmalya Barh
499
26
Breast Cancer Gene Therapy . . . . . . . . . . . . . . . . . . . . . . . . . . .
Gülay Büyükköroğlu, Duygu Abbasoğlu, and Candan Hızel
519
27
Clinical Trial Endpoints in Breast Cancer . . . . . . . . . . . . . . . .
Melvin George and Sandhiya Selvarajan
535
http://www.springer.com/978-81-322-0842-6