Contents Part I Omics Approaches in Breast Cancer 1 Omics Technologies Applied in Breast Cancer Research. . . . . Mariana Panal Cusati, Maria Herrera de la Muela, and Ignacio Zapardiel 3 2 Omics of Hereditary Breast Cancer . . . . . . . . . . . . . . . . . . . . . . Catherine A. Moroski-Erkul, Burak Yilmaz, Esra Gunduz, and Mehmet Gunduz 17 3 Oncogenes and Tumor Suppressor Genes as a Biomarker in Breast Cancer. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Eyyup Uctepe, Muradiye Acar, Esra Gunduz, and Mehmet Gunduz 41 4 Breast Cancer Genomics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Birendra Kumar 53 5 Epigenomics of Breast Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . Kursat Oguz Yaykasli, Ertugrul Kaya, and Emine Yaykasli 105 6 Nutrigenomics in Breast Cancer. . . . . . . . . . . . . . . . . . . . . . . . . Shailendra Dwivedi, Shailja Shukla, Apul Goel, Praveen Sharma, Sanjay Khattri, and Kamlesh Kumar Pant 127 7 Long Noncoding RNAs in Breast Cancer: Implications for Pathogenesis, Diagnosis, and Therapy . . . . . . . . . . . . . . . . . Jaroslav Juráček, Robert Iliev, Marek Svoboda, and Ondrej Slaby 8 Breast Cancer MicroRNAs: Clinical Biomarkers for the Diagnosis and Treatment Strategies. . . . . . . . . . . . . . . . . . . Gowhar Shafi, Tarique N. Hasan, Naveed Ahmed Syed, Ananta Paine, Jesper Tegner, and Anjana Munshi 153 171 9 Breast Cancer Proteomics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Ida Pucci-Minafra 183 10 Metabolomics in Breast Cancer . . . . . . . . . . . . . . . . . . . . . . . . . Maria C. Calomarde, Javier De Santiago, and Ignacio Zapardiel 211 xxi Contents xxii 11 Lipidomics in Breast Cancer. . . . . . . . . . . . . . . . . . . . . . . . . . . . Alvin Kamili and Jennifer A. Byrne 225 12 Breast Cancer Stem Cells and Cellomics. . . . . . . . . . . . . . . . . . Esin Demir, Bilge Atar, Dipali Dhawan, Debmalya Barh, Mehmet Gunduz, and Esra Gunduz 245 13 Omics of Male Breast Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . Zahide Nur Unal, Gülhan Kaya, Debmalya Barh, Esra Gunduz, and Mehmet Gunduz 265 14 Omics of Chemoresistant and Metastatic Breast Cancer. . . . . Margarita Aguilera and Juan Antonio Marchal 277 15 Animal Models of Breast Cancer . . . . . . . . . . . . . . . . . . . . . . . . E.A. El-Abd, A.S. Sultan, E.A. Shalaby, and F. Matalkah 297 16 In Silico Disease Models of Breast Cancer. . . . . . . . . . . . . . . . . Anjana Munshi and Vandana Sharma 315 17 Systems Biology and Integrative Omics in Breast Cancer. . . . Enrique Hernández-Lemus 333 Part II 18 19 20 21 22 23 Breast Cancer: Next-Generation Diagnosis, Prognosis, and Therapy Gynecologic Considerations for Women with Breast Cancer. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . William R. Robinson III and Kaneez Fatima Ali Imaging Technologies and Applications in Early Diagnosis and Prognosis for Breast Cancer. . . . . . . . . . . . . . . . M. Mar Gil, Marcos Cuerva, Sara Iacoponi, Jose I. Sanchez-Mendez, and Ignacio Zapardiel 355 371 Breast Cancer Biomarkers for Risk Assessment, Screening, Detection, Diagnosis, and Prognosis. . . . . . . . . . . . . . . . . . . . . . Mukesh Verma and Debmalya Barh 393 Breast Circulating Tumor Cells: Potential Biomarkers for Breast Cancer Diagnosis and Prognosis Evaluation. . . . . . Phuc Van Pham 409 Molecular Diagnosis of Metastasizing Breast Cancer Based Upon Liquid Biopsy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Shailendra Dwivedi, Apul Goel, Sadashiv, Arti Verma, Shailja Shukla, Praveen Sharma, Sanjay Khattri, and Kamlesh Kumar Pant Exhaled Volatile Organic Compounds as Noninvasive Markers in Breast Cancer. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Orna Barash and Hossam Haick 425 461 Contents xxiii 24 25 Breast Cancer Therapy–Classical Therapy, Drug Targets, and Targeted Therapy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Eugenia Ch Yiannakopoulou 483 Pharmacogenomics–Pharmacoepigenomics of Breast Cancer Therapy: Clinical Implications . . . . . . . . . . . . . . . . . . . Eugenia Ch Yiannakopoulou and Debmalya Barh 499 26 Breast Cancer Gene Therapy . . . . . . . . . . . . . . . . . . . . . . . . . . . Gülay Büyükköroğlu, Duygu Abbasoğlu, and Candan Hızel 519 27 Clinical Trial Endpoints in Breast Cancer . . . . . . . . . . . . . . . . Melvin George and Sandhiya Selvarajan 535 http://www.springer.com/978-81-322-0842-6
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