Alzheimer's Therapeutics in Asia-Pacific Market Size, Share and Growth To 2021: Hexa Reports

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Alzheimer's Therapeutics in Asia-Pacific Market Size,
Share, Growth, Treatment, Analysis, Symptoms, Emerging
Trends and Opportunities to 2021
Alzheimer’s Therapeutics in Asia-Pacific Markets to 2021 - Growth Driven by Rising Prevalence, Growing
Awareness and Expected Launch of Disease Modifying Therapies
Alzheimer’s Disease (AD) is an irreversible, progressive neurodegenerative disease, characterized by
cognitive impairment, memory loss and functional decline. Symptoms typically begin to first occur in
patients in their mid-sixties, appearing in varying stages. The pathological features of AD comprise
histopathological changes within the brain.
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Mild Cognitive Impairment (MCI) is a heterogeneous condition between normal cognition and dementia,
whereby cognitive changes in mental abilities, such as memory or thinking, are affected. Almost all cases
of AD begin with MCI, but it should be noted that not all patients with MCI go on to develop AD.
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Although there is a high degree of failure and uncertainty within the R&D of AD drugs, the number of
drugs in the pipeline is considerable, at 559. The majority of the pipeline products are novel, and there
are only seven repositioned drugs and five generic drugs. This shows progression in terms of the
different molecules being developed as therapeutic agents within the AD pipeline.
The AD market has a lack of therapeutic options.
 Which classes of drug dominate the market?
 What newly approved therapies have entered the market?
 How do the leading marketed therapies compare clinically?
 How will the new therapies be positioned in the treatment of AD?
 How have selected late-stage pipeline therapies performed in clinical trials?
 The pipeline contains a range of molecule types and molecular targets, including those that are well
established in AD, and novel, first-in-class therapies.
 Which molecular targets appear most frequently in the pipeline?
 AD clinical trials have an overall attrition rate of 94%.
 What are the failure rates for individual Phases of clinical development?
 How do AD clinical trial characteristics, including failure rate, duration, and size compare against
respiratory and industry averages?
 The AD market is forecast to rise from a value of $3 billion in 2014 to $5.1 billion in 2021, at a CAGR
of 7.9% across the four Asia-Pacific markets assessed.
 How much of a role will disease prevalence and new product approvals play in market growth?
 Will generic competition have a significant impact on the market over the forecast period?
There have been 170 licensing deals and 104 co-development deals pertaining to AD products since
 Which territories show the most deal activity?
 What were the trends in deal completion by product stage of development?
 What were the conditions of the key licensing or co-development deals to take place in AD?
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Reasons to buy
This report will allow you to –
1. Understand the current clinical and commercial landscape through a comprehensive study of
disease pathogenesis, diagnosis, prognosis, and the current treatment algorithm used in AD.
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2. Assess the safety and efficacy of current treatment options, with extensive product profiles on
prominent marketed therapies, and a heatmap directly comparing safety and efficacy data.
3. Analyze the AD pipeline and stratify by stage of development, molecule type, and molecular target.
The most promising late-stage therapies are profiled and assessed in terms of clinical performance
and competitiveness, alongside a single-product forecast.
4. Predict growth in market size in four Asia-Pacific markets, with in-depth market forecasting from
2014 to 2021. The forecasts will provide an understanding of how epidemiology trends, new drug
entries, and patent expirations will influence market value.
5. Identify commercial opportunities in the AD deals landscape by analyzing trends in licensing and
co-development deals, and by profiling the most significant deals that have occurred in this
indication in recent years.
Table Of Content
1 Table of Contents
1.1 List of Tables
1.2 List of Figures
2 Introduction
2.1 Disease Introduction
2.2 Epidemiology
2.3 Symptoms
2.4 Etiology and Pathophysiology
2.5 Diagnosis
2.6 Disease Stages
2.7 Prognosis
2.8 Treatment Options
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3 Marketed Products
3.1 Overview
3.2 Acetylcholinesterase Inhibitors
3.3 NMDA Receptor Antagonists
3.4 AChEI and NMDA Receptor Antagonists
3.5 Heat Map - Marketed Products Overview
4 Pipeline Analysis
4.1 Pipeline by Stage of Development, Molecule Type, Route of Administration and Program Type
4.2 Pipeline Analysis by Mechanism of Action
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4.3 Promising Pipeline Candidates
4.4 Heat Map for Pipeline Products
5 Clinical Trial Analysis
5.1 Failure Rate
5.2 Clinical Trial Size
5.3 Clinical Trial Duration
5.4 Summary of Clinical Trial Metrics
6 Multi-Scenario Forecast
6.1 Geographical Markets
6.2 Asia-Pacific Market
6.3 India
6.4 China
6.5 Australia
6.6 Japan
7 Drivers and Barriers
7.1 Drivers
7.2 Barriers
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Alzheimer’s Disease (AD) is an irreversible, progressive neurodegenerative disease, characterized by cognitive impairment, memory loss and functional decline.