Download the final program - 8° MS-Pharmaday

Complex substances for Botanical Drugs, Herbal Medicinal Products,
Medical Devices, Medical Foods
@ Aboca
Aboca ‐‐ Sansepolcro
Sansepolcro
@
June 11‐13,
11‐13, 2014
2014
June
‐1‐
Organised by
Under the patronage of
Centro Studi e Ricerche
“Giovanni Galli” ‐ UniMI
‐2‐
COMMITTEES
SCIENTIFIC COMMITTEE
Valentino Mercati (Chairman, Aboca)
Vincenza Andrisano (Università di Bologna)
Giuseppe Avellone (Università di Palermo)
Gianluca Bartolucci (Università di Firenze)
Marina Carini (Università di Milano)
Donatella Caruso (Università di Milano)
Luigi Colombo (Merck Serono)
Maristella Colombo (Nerviano Medical Sciences)
Nunziatina De Tommasi (Università di Salerno)
Gianluca Giorgi (Università di Siena)
Luca Grigi (Aboca)
Jacopo Lucci (Aboca)
Anna Maidecchi (Aboca)
Marcello Marchetti (Angelini, Pomezia)
Gabriella Massolini (Università di Pavia)
Luisa Mattoli (Aboca)
Pietro Traldi (CNR, Padova)
Sauro Vittori (Università di Camerino)
ORGANISING COMMITTEE
Luisa Mattoli (Chairman, Aboca)
Giuliana Bianco (Università della Basilicata)
Michele Boriosi (Aboca)
Michela Burico (Aboca)
Vincenzo Cunsolo (Università di Catania)
Anna Zita Di Carlo (Aboca)
Roberta Galarini (IZSUM, Perugia)
Fulvio Magni (Università di Milano Bicocca)
Giorgio G. Mellerio (Università di Pavia)
Michele Suman (Barilla, Parma)
CONFERENCE SECRETARIAT
Ufficio Relazioni Esterne (Aboca)
‐3‐
The 8th MS‐Pharmaday conference is kindly
supported and sponsored by:
‐4‐
SCIENTIFIC PROGRAM
Wednesday, June 11th, 2014
11:00
Shuttle bus from the Arezzo railway station
11:30 – 14:30
REGISTRATION
12:00
SATELLITE WORKSHOP
Waters: La mobilità ionica e sue applicazioni nel settore
alimentare
Sergio Gallo, Waters
13:00
LUNCH @ ABOCA
14:30
WELCOME & OPENING REMARKS
Valentino Mercati
Aboca
Luisa Mattoli
Aboca
Gabriella Massolini Univ. Pavia
Gianluca Giorgi
Univ. Siena
DSM Awards & Fellowships Ceremony
15:00
15:00
15:40
Session 1
Chair: Luisa Mattoli, Maristella Colombo
THE HOLISTIC VIEW OF NATURAL EXTRACTS
Pietro Traldi , Valentino Mercati, CNR, Padova, Aboca (Italy)
DSM Award for Young Researchers 2014
QUANTIFICATION OF “CHOLESTEROL LOWERING” SOYASAPONINS
IN LEGUMES AND ASSESSMENT OF THEIR BIOACCESSIBILITY
G. Caprioli, G. Sagratini, M. Ricciutelli, S. Vittori, University of
Camerino, Camerino (Italy)
16:10
Poster Session ‐ coffee break
‐5‐
17:00
17:00
17:30
17:30
Session 2
Chair: Marcello Marchetti
THE CLASH OF THE “OMICS” AND ITS APPLICATIONS
Lello Zolla et al. University della Tuscia, Viterbo (Italy)
End of session
Shuttle bus to Aboca Museum in Sansepolcro: guided tour
‐6‐
Thursday, June 12th, 2014
9:00
9:00
9:40
Session 3
Chair: Gianluca Bartolucci, Giuliana Bianco
ACCELERATING EXPERIMENTAL METABOLITE IDENTIFICATION BY
BIO COMPUTATIONAL MODELING
G. Cruciani, University of Perugia (Italy)
CHARACTERIZATION OF HEALTH‐PROMOTING GRAPE
COMPOUNDS BY SUSPECT SCREENING METABOLOMICS
R. Flamini, M. De Rosso, A. Dalla Vedova, A. Panighel, L. Bavaresco,
CRA‐VIT, Conegliano (TV) (Italy)
10:00
LIQUID CHROMATOGRAPHIC/ELECTROSPRAY IONIZATION
TANDEM MASS SPECTROMETRIC STUDY OF POLYPHENOLIC
COMPOUND IN BERRIES
Samuele Scurati, ABSciex
10:20
STABILITY IN BIOLOGICAL FLUIDS BY LC‐MS/MS ANALYSIS OF
MULTI‐DRUGS RESISTENCE INHIBITORS
M. Menicatti, L. Guandalini, S. Dei, E. Floriddia, E. Teodori, G.
Bartolucci, University of Florence, Sesto F.no (Italy)
10:40
Poster Session ‐ coffee break
11:30
Session 4
Chair: Donatella Caruso, Roberta Galarini
GC‐MS/MS ANALYSIS OF TRACE LEVEL DECHLORANE FLAME
RETARDANTS IN FOOD AND FEED AND POSSIBLE EXPOSURE
ROUTE TO HUMANS
C. Calaprice, B. L’Homme, C. Brasseur, C. D. Calvano, J.‐F. Focant,
Politecnico di Bari (Italy)
11:30
11:50
BIOTHERAPEUTICS: THE BRUKER MS TOOLBOX FOR IN DEPTH
CHARACTERIZATION
Catherine Evans, Bruker Daltonics, UK
12:10
LIPIDOME OF FARMED Sparus aurata: LYSOPHOSPHATIDYL‐
CHOLINES AS SEAFOOD QUALITY BIOMARKERS
S. Granafei, I. Losito, S. Salivo, P. Q. Tranchida, L. Mondello, F.
Palmisano, T.R.I. Cataldi, University of Bari (Italy)
‐7‐
12:30
DEVELOPMENT OF A MULTICLASS METHOD FOR THE
DETERMINATION OF VETERINARY DRUG RESIDUES IN MEAT
S. Moretti, G. Dusi, S. Pellicciotti, G. Saluti, D. Giusepponi, R. Rossi,
R. Galarini, IZSUM, Perugia (Italy)
12:50
13:00
14:30
End of session
14:30
LUNCH @ ABOCA
Session 5
Chair: Vincenza Andrisano, Giorgio Mellerio
COMPREHENSIVE LIQUID CHROMATOGRAPHY COUPLED TO
TANDEM MASS SPECTROMETRY FOR THE CHARACTERIZATION OF
POLYPHENOLS IN MATE EXTRACTS
F. Cacciola, P. Donato, P. Dugo, L. Mondello, University of Messina
(Italy)
15:00
UPC2™ : UNA SOLUZIONE ANALITICA PER INCREMENTARE LA
SELETTIVITÀ NEI LABORATORI CROMATOGRAFICI
A. Perissi, Waters Italia, Milano (Italy)
15:20
FURTHER INSIGHTS INTO THE MECHANISM OF ACTION OF THE
ANTI‐CANCER DITERPENE ORIDONIN PROVIDED BY DIFFERENT
COMPOUND‐CENTRIC PROTEOMIC APPROACHES
F. Dal Piaz, M. Vasaturo, R. Cotugno, M. A. Belisario, N. De
Tommasi, University of Salerno, Fisciano (SA, Italy)
15:40
MASS SPECTROMETRIC CHARACTERIZATION OF HUMAN SERUM
ALBUMIN DIMER: A NEW POTENTIAL BIOMARKER IN CHRONIC
LIVER DISEASES
M. Naldi, M. Baldassarre, M. Nati, M. Laggetta, F. A. Giannone, M.
Domenicali, P. Caraceni, M. Bernardi, C. Bertucci, S. Orsola‐
Malpighi University Hospital, Bologna (Italy)
16:00
DESI‐HRMS FOR THE FAST AND SENSITIVE INVESTIGATION OF
MODEL DRUG INTERACTIONS WITH NATURAL POLYSACCHARIDE
IN TABLETS
L. Elviri, S. De Robertis, S. Baldassarre, R. Bettini, University of
Parma (Italy)
16:20
ACID CATALYZED GLUCOSE DEHYDRATION IN THE GAS PHASE:
A MASS SPECTROMETRIC APPROACH
A. Ricci, B. Di Rienzo, F. Pepi, A. Troiani, S. Garzoli, P.Giacomello,
Second University of Naples, Caserta (Italy)
‐8‐
16:40
16:45
End of Session
20:30
Social dinner
Shuttle bus to the museum in Monterchi to admire the Madonna
del Parto fresco by Piero della Francesca, a very famous early
Italian renaissance painter (1412‐1492)
‐9‐
Friday, June 13th, 2014
9:15
9:15
9:55
Session 6
Chair: Gabriella Massolini, Sauro Vittori
HIGH RESOLUTION LC‐MS APPROACHES FOR DECIPHERING THE
COMPLEXITY OF NATURAL EXTRACTS – NOVEL METABOLITE
PROFILING, DEREPLICATION AND METABOLOMICS ASPECTS
Jean‐Luc Wolfender, University of Geneva (Switzerland)
COMPARATIVE STUDY ON DIFFERENT POPULATIONS OF
CULTIVATED, WILD AND COMMERCIAL GENTIANA LUTEA L. BY
LC/ESI‐MS AND HPLC/DAD
A. M. Mustafa, G. Caprioli, M. Ricciutelli, F. Maggi, G. Sagratini, S.
Vittori, University of Camerino (Italy)
10:15
ESSENTIAL OIL CHEMOTYPIFICATION AND SECRETORY
STRUCTURES OF THE NEGLECTED HORTICULTURAL CROP
SMYRNIUM OLUSATRUM L. (APIACEAE)
F. Maggi, A. Bianco, L. Maleci Bini et al. ‐ University of Camerino
(Italy)
10:35
SPETTROMETRIA DI MASSA AD ALTISSIMA RISOLUZIONE NELLE
APPLICAZIONI IN AMBITO FARMACEUTICO E BIOFARMACEUTICO
P. Nebuloni, Thermo Fisher Scientific S.p.A., Rodano (MI, Italy)
10:55
11:45
Poster Session ‐ coffee break
11:45
Session 7
Chair: Fulvio Magni, Marina Carini
MALDI IMAGING MASS SPECTROMETRY (IMS) OF CORONAL
SECTIONS OF MICE BRAIN: PROTEINS EXPRESSION OF SERT
KNOCKOUT VERSUS WILD‐TYPE
R. Zianni, R. Ye, J. Norris, R. D. Blakely, T.R.I Cataldi, R. M. Caprioli
University of Bari (Italy)
12:05
MALDI‐IMS ON EX‐VIVO FINE NEEDLE ASPIRATION (FNA) OF
FOLLICULAR AND MEDULLARY THYROID TUMORS
G. De Sio, F. Pagni, V. Mainini, M. Garancini, A. Vanzati, V. Giardini,
M. Scardilli, A. J. Smith, P. Goffredo, F. Magni, University of Milano‐
Bicocca, Milan (Italy)
12:25
Valentino Mercati, presidente e fondatore di Aboca, racconta: un
progetto di vita, imprenditorialità, giovani
‐ 10 ‐
12:50
End of session …. Arrivederci!!
13:00
LUNCH @ ABOCA
14:30
Shuttle bus and guided tour of the production facility and
laboratories at the headquarters of Aboca in Pistrino
16:30
Shuttle bus to the Arezzo railway station
‐ 11 ‐
POSTER COMMUNICATIONS
P1
OFFICINAL HERBS: FINGERPRINT OF HYDROALCOHOLIC EXTRACTS
BY HPLC‐UV‐MS
Valentina Santoro, Ilenia Siciliano, Federica Dal Bello, Claudio
Medana and Claudio Baiocchi, University of Turin (Italy)
P2
COMPOSITION AND BIOLOGICAL ACTIVITY OF ESSENTIAL OILS
FROM THE CAMEROONIAN BUSH ONION (AFROSTYRAX
LEPIDOPHYLLUS) AND GARLIC TREE (SCORODOPHLOEUS ZENKERI)
Hervet P. D. Foganga, Filippo Maggi, Luciano Barboni, Massimo
Bramucci, Giulio Lupidi, Fabrizio Papa, Dezemona Petrelli, Luana
Quassinti, Léon A. Tapondjou, Luca A. Vitali, Hilaire M. Womeni,
Sauro Vittori, University of Camerino, Camerino (Italy)
P3
CHARACTERIZATION OF ESSENTIAL OIL COMPONENTS IN
COSMETIC PRODUCTS BY GC‐MS
A. De Simone, V. Andrisano, University of Bologna, Rimini (Italy)
P4
TARGETED LC‐MS/MS FOR THE SIMULTANEOUS AND SENSITIVE
QUANTITATIVE PROFILING OF NATURALLY OCCURRING ACTIVE
COMPOUNDS IN GINKGO BILOBA
Lisa Elviri, Flavia Bianchi, Lorenza Vicentini, Paolo Andreatta,
Ruggero Bettini, Università di Parma, Parma (Italy)
P5
GLUCOSINOLATES AND ACYL CONJUGATES DIVERSITY IN
BARBAREA VULGARIS SEEDS EXPLORED BY LC/MS USING
FOURIER‐TRANSFORM ION CYCLOTRON RESONANCE MASS
SPECTROMETRY AND INFRARED MULTIPHOTON DISSOCIATION
(FTICR‐MS IRMPD)
G. Bianco, Agerbik N., F. Lelario, R. Pascale, S. A. Bufo, T. R. I.
Cataldi, University of Basilicata, Potenza (Italy)
P6
MYRTUS COMMUNIS LEAF EXTRACTS TESTED ON PROKARYOTIC
AND MAMMALIAN CELLS
S. Bernardini, F. Mastrogiovanni, L. Gallipoli, G.M. Balestra, D.
Pollini, V. Gallorini, D. Triggiani, E. Ovidi, A. Tiezzi, Università degli
Studi della Tuscia, Viterbo (Italy)
P7
URINARY METABOLIC PROFILING OF RATS TREATED WITH
CURCUMIN USING HPLC‐MS
Matteo Stocchero, Stefano Dall’Acqua, Elisabetta Schievano, S‐IN
Soluzioni Informatiche, Vicenza (Italy)
‐ 12 ‐
P8
CORRELATION BETWEEN TRICHOME DENSITY, ARTEMISININ
ACCUMULATION AND ADS GENE ACTIVITY IN ARTEMISIA ANNUA
Palmira Ianni, , Andrea Tartarini, Loretta Pace, Laura Spanò,
Università degli Studi dell’Aquila, L’Aquila (Italy)
P9
ALTERNATIVE BIOLOGICAL FLUID FOR METABOLOMIC
APPROACHES TO SCREEN STEROID ABUSE IN BEEF CATTLE
Giorgio Saluti, Simone Moretti, Jennifer Pascali, Giancarlo
Biancotto, Roberto Angeletti, Nicola Cimino, Anna Calì, Roberta
Galarini, IZSUM, Perugia (Italy)
P10
VALIDATION OF AN HPLC‐MS/MS METHOD FOR QUANTITATIVE
DETERMINATION OF TRABECTEDIN IN TUMOR TISSUES FROM
XENOGRAFT MICE
Laura Ceriani, Monique Zangarini, Simonetta Andrea Licandro,
Maurizio D’Incalci, Massimo Zucchetti, IRCCS “Mario Negri”,
Milan (Italy)
P11
THE INFLUENCE OF TYPE‐2 DIABETES MELLITUS ON
MITOCHONDRIAL PROTEIN PROFILE
Simona Porcu, Annunziata Lapolla, Mario Zoratti, Francesco
Piarulli, Daniela Basso, Marco Roverso, Roberta Seraglia, Pietro
Traldi, Università di Padova, Padova (Italy)
P12
DETECTION OF ANTINEOPLASTIC DRUGS BY LDI, MALDI AND
SALDI METHODOLOGIES
E. Calandra, S. Crotti,E. Marangon,M. Agostini,G. Toffoli, P.Traldi,
CNR‐‐‐IENI, Padova (Italy)
P13
DETERMINATION OF THE DEPTH OF PACLITAXEL PENETRATION IN
PERITONEAL WALL AFTER HYPERTHERMIC INTRAPERITONEAL
CHEMOTHERAPY BY NANO‐PARTICLE ASSISTED LASER
DESORPTION IONIZATION MASS SPECTROMETRY IMAGING
Lavinia Morosi, Massimo Zucchetti, Silvia Giordano, Enrico Davoli,
Federico Coccolini, Luca Ansaloni, Maurizio D’Incalci, IRCCS ”Mario
Negri”, Milano (Italy)
P14
RATIONAL DESIGN AND ANALYTICAL CHARACTERIZATION BY
MASS SPECTROMETRY OF POTENTIAL NEO‐GLYCOVACCINES
AGAINST TUBERCULOSIS
Alice Pedrali, Sara Tengattini, Caterina Temporini, Teodora Bavaro,
Immacolata Serra, Luciano Piubelli, Marco Terreni, Gabriella
Massolini, University of Pavia, Pavia (Italy)
‐ 13 ‐
P15
FAST GC‐TOF MS ANALYSIS OF MEDIUM CHAIN FATTY ACIDS
(MCFA) IN COLORECTAL PATHOLOGIES MONITORING
E. Agnoletto, S. Crotti, V. Di Marco, U. Saini, M. Bergna, M.
Agostini, P. Traldi, University of Padua, Padova (Italy)
P16
A NEW COMPLETE PROTEOMIC APPROACH: THE STUDY CASE OF
ERYTHROPOIETIN
Alessandra Gianoncelli, Michela Bertuzzi, Sara Bonini, Rajesh
Kumar, Sara Vezzoli, Maurizio Memo, University of Brescia, Brescia
(Italy)
P17
ANALYTICAL CHARACTERIZATION OF THE MAIN COMPONENTS IN
PATCHES RESPONSIBLE FOR ALLERGIC CONTACT DERMATITIS
Cosima D. Calvano, Antonella Aresta, Nicoletta Ditaranto, Caterina
Foti, Carlo G. Zambonin, Università degli Studi di Bari Aldo Moro,
Bari (Italy)
P18
ESI‐MS FINGERPRINT AND FRACTAL DIMENSION OF COLILEN IBS®
Michela Burico, Luisa Mattoli, Giada Fodaroni, Valentino Mercati,
Pietro Traldi, Eugenio Ragazzi, Aboca SpA, Sansepolcro (AR, Italy)
P19
CHARACTERIZATION OF MYRIOCIN AND SOME DERIVATIVES BY
ELECTROSPRAY AND QTRAP MASS SPECTROMETRY
Federico Maria Rubino, Paola Signorelli, Jelena S. Lazarevic´, Rita
Paroni, University of Milan (Italy)
‐ 14 ‐
DSM Awards for Young Researchers 2014
PREMIO DSM‐SCI PER GIOVANI OPERANTI NEL CAMPO DELLA
SPETTROMETRIA DI MASSA
La Divisione di Spettrometria di Massa della Società Chimica Italiana ha
istituito a partire dall’anno 2000 il “Premio DSM‐SCI per giovani operanti nel
campo della spettrometria di massa” che conferisce a un giovane di età non
superiore a 35 anni per il miglior lavoro a carattere sperimentale, tesi di
laurea, dottorato di ricerca o articolo a stampa, avente come settore di
riferimento la spettrometria di massa.
Vincitore per l’anno 2014 è il
Dr Giovanni Caprioli
Università di Camerino
per lo studio e la caratterizzazione di alimenti mediante un uso prominente
della spettrometria di massa.
Vincitori delle precedenti edizioni:
2000: dr David Bongiorno
2001: dr.ssa Antonina Gucciardi
2002: dr.ssa Maria Pia Vitale
2003: dr.ssa Sara Rinalducci
2004: dr.ssa Ester Marotta
2005: dr.ssa Ingrid Zagnoni
2006: dr.ssa Vera Muccilli
2007: ex‐equo dr.sse Francesca Attanasio, Maria Chiara Monti
2008: dr.ssa Valeria Cavatorta
2009: dr.ssa Caterina Fraschetti
2010: dr.ssa Alessandra Tata
‐ 15 ‐

Download Report