UNIVERSITA' DEGLI STUDI DELLA BASILICATA DIPARTIMENTO DI SCIENZE _____________________________________________________________________________ Prof. LUIGI MILELLA _____________________________________________________________________ CURRICULUM SCIENTIFICO Ricercatore confermato dal 2008 in “Biologia Applicata” SSD BIO15, Docente presso il Corso di Studi in Farmacia dell’Università degli Studi della Basilicata dove svolge, attività di ricerca finalizzata allo studio farmacognostico e nutraceutico di diverse specie vegetali e marine (Es. Fragaria spp.; Citrus spp.; Opuntia spp Spugne.). Si è occupato della valutazione dell’attività biologica e potenziale applicazione in ambito farmaceutico di diversi estratti e composti naturali (piante superiori e spugne). Ha partecipando come Host Diver, a bordo della nave-laboratorio Hatteras, alla spedizione oceanografica effettuata in collaborazione con il gruppo del prof. J. R Pawlik dell’UNCW, volto alla realizzazione di un innovativo progetto di ricerca per lo studio degli organismi marini. Si è inoltre occupato dell’analisi del genoma e della sua correlazione con la biosintesi di metaboliti secondari in diverse specie vegetali di origine sudamericana utilizzate in medicina tradizionale come lo yacon [Smallanthus sonchifolius (Poepp. et Endl.)], Pongamia spp, Jatropha spp. Ha lavorato presso il TEAGASC di Dublino e presso il VURV di Praga, due importanti centri di ricerca, con i quali continuano produttive collaborazioni scientifiche. L’attività di ricerca si concretizza nelle pubblicazioni di seguito elencate, molte in collaborazione con importanti istituti di ricerca scientifica a livello europeo. Since 2008 he works as Researcher in "Pharmaceutical Biology" SSD BIO15, Faculty of Pharmacy, University of Basilicata (Italy), where he carries out research focused on the study of biological activity, chemical structure and biosynthesis of secondary metabolites in different plant species. The plant species studied come from South American origin and were used in traditional medicine [e.g. Smallanthus sonchifolius (Poepp. et Endl.), Thymus spp., Salvia spp., Pongamia spp, Jatropha spp] or used as nutraceuticals [e.g. Fragaria spp. Citrus spp. Opuntia spp.] Research fellow at TEAGASC "The National Food Centre" of Dublin at the "Research Centre of Crop Productions" in Prague. Several publication are in collaboration with important European Research Institutes. _______________________________________________________________________ Principali Pubblicazioni / Selected Papers and Publications: Milella, L., Bader, A., De Tommasi, N., Russo, D., Braca, A. Antioxidant and free radical-scavenging activity of constituents from two Scorzonera species. (2014) Food Chemistry, 160, pp. 298-304. Rejthar, J., Viehmannova, I., Cepkova, P.H., Fernández, E., Milella, L. In vitro propagation of Drosera intermedia as influenced by cytokinins, pH, sucrose, and nutrient concentration. (2014) Emirates Journal of Food and Agriculture, 26 (6), pp. 558-564. Moravec, I., Fernandez, E., Vlkova, M., Milella, L. Ethnobotany of medicinal plants of northern Ethiopia (2014). Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas, 13 (2), pp. 126-134. Žiarovská, J., Cusimamani, E.F., Russo, D., Milella, L. Difference on ITS regions among Yacon genotypes and Smallanthus Spp Viale dell’Ateneo lucano, 10 – 85100 Potenza Telefono 0971-205602- 205773 UNIVERSITA' DEGLI STUDI DELLA BASILICATA DIPARTIMENTO DI SCIENZE (2014) Emirates Journal of Food and Agriculture, 26 (1), pp. 60-65. Fernández, E.C., Rajchl, A., Lachman, J., Čížková, H., Kvasnička, F., Kotíková, Z., Milella, L., Voldřich, M. Impact of yacon landraces cultivated in the Czech Republic and their ploidy on the short- and longchain fructooligosaccharides content in tuberous roots (2013) LWT - Food Science and Technology, 54 (1), pp. 80-86. Janská, A., Hodek, J., Svoboda, P., Zámečník, J., Prášil, I.T., Vlasáková, E., Milella, L., Ovesná, J. The choice of reference gene set for assessing gene expression in barley (Hordeum vulgare L.) under low temperature and drought stress (2013) Molecular Genetics and Genomics, 288 (11), pp. 639-649. Cited 3 times. Padula, M.C., Lepore, L., Milella, L., Ovesna, J., Malafronte, N., Martelli, G., De Tommasi, N. Cultivar based selection and genetic analysis of strawberry fruits with high levels of health promoting compounds (2013) Food Chemistry, 140 (4), pp. 639-646. Bonomo, M.G., Milella, L., Martelli, G., Salzano, G. Stress response assessment of Lactobacillus sakei strains selected as potential autochthonous starter cultures by flow cytometry and nucleic acid double-staining analyses (2013) Journal of Applied Microbiology, 115 (3), pp. 786-795. Žiarovská, J., Fernández, E.C., Millela, L. A revised its nucleotide sequence gives a specifity for smallanthus sonchifolius (poepp. and endl.) and its products identification. (2013) Genetika, 45 (1), pp. 217-226. Calabrone, L., Milella, L., Greco, I., Martelli, G. Isolation of putative LAR (leucoanthocyanidin reductase) gene fragment differentially expressed in Jatropha curcas L. Leaves (2013) Emirates Journal of Food and Agriculture, 25 (3), pp. 225-230. Ovesná, J., Kučera, L., Vaculová, K., Milotová, J., Snape, J., Wenzl, P., Huttner, E., Kilian, A., Martelli, G., Milella, L. Analysis of the Genetic Structure of a Barley Collection Using DNA Diversity Array Technology (DArT) (2013) Plant Molecular Biology Reporter, 31 (2), pp. 280-288. Melnikovova, I., Havlik, J., Fernandez Cusimamani, E., Milella, L. Macamides and fatty acids content comparison in maca cultivated plant under field conditions and greenhouse (2012) Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas, 11 (5), pp. 420-427. Russo, D., Bonomo, M.G., Salzano, G., Martelli, G., Milella, L. Nutraceutical properties of citrus clementina juices (2012) Pharmacologyonline, 1 (SPL. 1), pp. 84-93. Ovesná, J., Kučera, L., Vaculová, K., Štrymplová, K., Svobodová, I., Milella, L. Validation of the β-amy1 transcription profiling assay and selection of reference genes suited for a RT-qPCR assay in developing barley caryopsis UNIVERSITA' DEGLI STUDI DELLA BASILICATA DIPARTIMENTO DI SCIENZE (2012) PLoS ONE, 7 (7), art. no. e41886, . Marandino, A., De Martino, L., Mancini, E., Milella, L., De Feo, V. Chemical composition and possible in vitro antigermination activity of three Hypericum essential oils (2011) Natural Product Communications, 6 (11), pp. 1735-1738. Ovesná, J., Kučera, L., Horníčková, J., Svobodová, L., Stavělíková, H., Velíšek, J., Milella, L. Diversity of S-alk(en)yl cysteine sulphoxide content within a collection of garlic (Allium sativum L.) and its association with the morphological and genetic background assessed by AFLP (2011) Scientia Horticulturae, 129 (4), pp. 541-547. Milella, L., Caruso, M., Galgano, F., Favati, F., Padula, M.C., Martelli, G. Role of the cultivar in choosing Clementine fruits with a high level of health-promoting compounds (2011) Journal of Agricultural and Food Chemistry, 59 (10), pp. 5293-5298. Milella, L., Martelli, G., Salava, J., Fernandez, E., Ovesná, J., Greco, I. Total phenolic content, RAPDs, AFLPs and morphological traits for the analysis of variability in Smallanthus sonchifolius. (2011) Genetic Resources and Crop Evolution, 58 (4), pp. 545-551. Sofo, A., Milella, L., Tataranni, G. Effects of Trichoderma harzianum strain T-22 on the growth of two Prunus rootstocks during the rooting phase (2010) Journal of Horticultural Science and Biotechnology, 85 (6), pp. 497-502. Martelli, G., Zaccagnino, N., Milella, L., Greco, I. Characterization of the DNA methylation activity by gene expression analysis in Fragaria vesca (2009) Acta Horticulturae, 842, pp. 569-572. Gliubizzi, D., Martelli, G., Milella, L., Giordano, S., Greco, I. Characterization of Fragaria vesca - Rhizoctonia fragariae interaction by gene expression analysis (2009) Acta Horticulturae, 842, pp. 565-568. Fernández, E.C., Viehmannová, I., Lachman, J., Milella, L. Yacon [Smallanthus sonchifolius (Poeppig & Endlicher) H. Robinson]: A new crop in the Central Europe (2006) Plant, Soil and Environment, 52 (12), pp. 564-570. Milella, L., Saluzzi, D., Lapelosa, M., Bertino, G., Spada, P., Greco, I., Martelli, G. Relationships between an Italian strawberry ecotype and its ancestor using RAPD markers (2006) Genetic Resources and Crop Evolution, 53 (8), pp. 1715-1720. Milella, L., Lapelosa, M., Greco, I., Martelli, G. Differential expressed genome fractions and transcriptional factor domain isolation in Fragaria spp. (2006) Acta Horticulturae, 708, pp. 489-496. Ismaili, H., Milella, L., Fkih-Tetouani, S., Ilidrissi, A., Camporese, A., Sosa, S., Altinier, G., Della Loggia, R., Aquino, R. In vivo topical anti-inflammatory and in vitro antioxidant activities of two extracts of Thymus satureioides leaves (2004) Journal of Ethnopharmacology, 91 (1), pp. 31-36. 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