cv Manara 032014 ing - Città della Speranza

FORMATO
EUROPEO
PER IL CURRICULUM
VITAE
PERSONAL INFORMATION
Name
Address
Telephone
MANARA ELENA
CORSO STATI UNITI, 4 35127 PADOVA (PD)
+390498215488
Fax
E-mail
Nationality
[email protected]
Italiana
I
Date of birth
30/04/1981
WORK EXPERIENCE
8/2013-now
8/2011-8/2013
8/2010-7/2011
10/2008-7/2010
01/2007-10/2008
02/2006-12/2006
09/2004-10/2005
09/2004-10/2005
05/2003-09/2003
Employed as a Post Doc at the Istituto di Ricerca Pediatrico in Padova.
Post Doc Research fellowship at Onco-hematology laboratory, Department of Pediatrics,
University of Padova, in the project “Ruolo di ICER nella leucemia acuta mieloide”.
European Research fellowship at Onco-hematology laboratory, Department of Pediatrics,
University of Padova, in the MONAD project “Engineering of molecular motors and cytoskeletal
filaments in a nano device for ultrasensitive diagnostic disease markers”.
visiting PhD student at UCLA, Los Angeles, CA in the laboratory of Professor Sakamoto KM
department of Pediatrics Hemato-oncology, works on a project regarding the regulation of CREB
by miRNA in a mouse model.
PhD student at the University of Padova, Italy, works on a project regarding CREB and acute
pediatric leukemia.
Fellowship “Città della Speranza” at the Onco-hematology laboratory of Professor Basso G,
Department of Pediatrics, University of Padova, for the project: “Diagnostica per leucemie,
linfomi non Hodgkin e non, sarcomi delle parti molli”.
training in the CRIBI laboratory of Professor Lanfranchi G, Department of Biology, University of
Padova, for the thesis “Analisi comparativa dei dati di espressione genica prodotti con la
tecnologia dei microarray di DNA”.
training in the CRIBI laboratory of Professor Lanfranchi G, Department of Biology, University of
Padova, for the thesis “Analisi comparativa dei dati di espressione genica prodotti con la
tecnologia dei microarray di DNA”.
training at the Department of Organic Chemistry in the laboratory of Professor Licini G,
University of Padova, for the thesis “N-o-NBS-aminoacidi α,α-disostituiti: studio della reazione di
formazione del legame amidico”.
EDUCATION
2007-2010
2000-2005
1998-1999
Pagina 1 - Curriculum vitae di
MANARA, Elena
PhD in “Developmental medicine and programming of science”, University of Padua, Italy
Magna cum laude. Bachelor in Sciences, Industrial Biotechnology, University of Padua, Italy
AFS program: senior year at the Mckinleyville high school, Mckinleyville, CA.
NATIVE LANGUAGE
ITALIAN
OTHER
• Reading
• Writing
• Speech
EXPERTISE
ENGLISH
Excellent
Excellent
Very Good
- Molecular biology techniques: PCR and RealTimePCR, DNA and RNA electrophoresis, Sanger
sequencing, DNA RNA and protein extraction, western blot, immunoprecipitation, plasmid
construction and recombination, immunofluorescence, immunohistochemistry.
- Cellular biology techniques: cell line culture, primary culture, transfection techniques, drug
treatment, bacteria culture and transformation, flowcitometry (cell cycle and annexinV/PI assay).
- In vivo models: mice: intraperitoneal, subcutaneous and tail vein injections, bone marrow
transplant, sacrifice.
Pagina 2 - Curriculum vitae di
MANARA, Elena
PUBLICATIONS
Pagina 3 - Curriculum vitae di
MANARA, Elena
•
Manara E, Bisio V, Masetti R, Beqiri V, Rondelli R, Menna G, Micalizzi
C,Santoro N, Locatelli F, Basso G, Pigazzi M. Core-binding factor
acute myeloidleukemia in pediatric patients enrolled in the AIEOP AML
2002/01 trial: screeningand prognostic impact of c-KIT mutations.
Leukemia. 2013 Nov 14. doi:10.1038/leu.2013.339.
•
Masetti R, Togni M, Astolfi A, Pigazzi M, Manara E, Indio V, Rizzari
C,Rutella S, Basso G, Pession A, Locatelli F. DHH-RHEBL1 fusion
transcript: a novelrecurrent feature in the new landscape of pediatric
CBFA2T3-GLIS2-positive acute myeloid leukemia. Oncotarget. 2013
Oct;4(10):1712-20.
•
Masetti R, Pigazzi M, Togni M, Astolfi A, Indio V, Manara E, Casadio
R,Pession A, Basso G, Locatelli F. CBFA2T3-GLIS2 fusion transcript is
a novelcommon feature in pediatric, cytogenetically normal AML, not
restricted to FAB M7subtype. Blood. 2013 Apr 25;121(17):3469-72.
doi: 10.1182/blood-2012-11-469825.
•
Pigazzi M, Manara E, Bisio V, Aveic S, Masetti R, Menna G, Zecca M,
Pession A,Locatelli F, Basso G. Screening of novel genetic aberrations
in pediatric acutemyeloid leukemia: a report from the AIEOP AML-2002
study group. Blood. 2012 Nov1;120(18):3860-2. doi: 10.1182/blood2012-09-454454.
•
Pigazzi M*, Manara E*, Bresolin S, Tregnago C, Beghin A, Baron E,
Giarin E, Cho EC, Masetti R, Rao DS, Sakamoto KM, Basso G.
MicroRNA-34b promoterhypermethylation induces CREB
overexpression and contributes to myeloidtransformation.
Haematologica. 2013 Apr;98(4):602-10. * Co-first
•
Sandoval S, Kraus C, Cho EC, Cho M, Bies J, Manara E, Accordi B,
Landaw EM,Wolff L, Pigazzi M, Sakamoto KM. Sox4 cooperates with
CREB in myeloidtransformation. Blood. 2012 Jul 5;120(1):155-65.
doi:10.1182/blood-2011-05-357418.
•
Pigazzi M, Masetti R, Martinolli F, Manara E, Beghin A, Rondelli R,
Locatelli F, Fagioli F, Pession A, Basso G. Presence of high-ERG
expression is anindependent unfavorable prognostic marker in MLLrearranged childhood myeloidleukemia. Blood. 2012 Jan
26;119(4):1086-7; author reply 1087-8. doi:10.1182/blood-2011-10385815. PubMed PMID: 22282493.
•
Pigazzi M, Manara E, Beghin A, Baron E, Tregnago C, Basso G. ICER
evokesDusp1-p38 pathway enhancing chemotherapy sensitivity in
myeloid leukemia. ClinCancer Res. 2011 Feb 15;17(4):742-52. doi:
10.1158/1078-0432.CCR-10-0886.
•
Pigazzi M, Manara E, Baron E, Basso G. miR-34b targets cyclic AMPresponsiveelement binding protein in acute myeloid leukemia. Cancer
Res. 2009 Mar15;69(6):2471-8. doi: 10.1158/0008-5472.CAN-083404.
•
Pigazzi M, Manara E, Baron E, Basso G. ICER expression inhibits
leukemiaphenotype and controls tumor progression. Leukemia. 2008
Dec;22(12):2217-25. doi:10.1038/leu.2008.244.

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