PUBLICATIONS
PAPERS（原著論文）
1.
Regulatory role of enteric mu and kappa opioid receptors in the release of acetylcholine
and norepinephrine from guinea pig ileum.
Shinji Nakayama, Kohtaro Taniyama, Shogo Matsuyama, Naohiro Ohgushi, Kengo
Tsunekawa, Chikako Tanaka
J. Pharmacol. Exp. Ther. 254: 792-798, 1990
2.
-Aminobutyric acid is a neuromodulator in sinus node of guinea pig heart.
Shogo Matsuyama, Naoaki Saito, Kohtaro Taniyama, Chikako Tanaka
Am. J. Physiol. 261 (Heart Circ. Physiol. 30): H1437-H1442, 1991
3.
Cisapride stimulates motility of the intestine via the 5-hydroxytryptamine receptors.
Kohtaro Taniyama, Shinji Nakayama, Koichiro Takeda, Shogo Matsuyama, Junji
Shirakawa, Isamu Sano, Chikako Tanaka
J. Pharmacol. Exp. Ther. 258: 1098-1104, 1991
4.
Dual effect of trimebutine on contractility of the guinea pig ileum via the opioid receptors.
Kohtaro Taniyama, Isamu Sano, Shinji Nakayama, Shogo Matsuyama, Koichiro Takeda,
Chika Yoshihara and Chikako Tanaka
Gastroenterology 101: 1579-1587, 1991
5.
Molecular structure of the C catalytic subunit of rat cAMP-dependent protein kinase and
differential expression of C and C isoforms in rat tissues and cultured cells.
Hisato Shuntoh, Norikazu Sakamoto, Shogo Matsuyama, Masakatsu Saitoh, Chikako
Tanaka
Biochem. et Biophys. Acta, 1131: 175-180, 1992
6.
GABA modulates neurotransmission in sinus node via stimulation of GABAA receptor.
Shogo Matsuyama, Naoaki Saito, Hisato Shuntoh, Kohtaro Taniyama, Chikako Tanaka
Am. J. Physiol. 264 (Heart Circ. Physiol. 33): H1057-H1061, 1993
7.
Thapsigargin induces an endothelium-dependent, intracellular calcium ion-dependent
vasodilation in vitro.
Shogo Matsuyama, Hisato Shuntoh, Shigenori Katayama, Chikako Tanaka
Life Sci. 53: 681-688, 1993
8.
Effect of heat shock on intracellular calcium mobilization in neuroblastoma x glioma
hybrid cells.
Shigenori Katayama, Hisato Shuntoh, Shogo Matsuyama, Chikako Tanaka
J. Neurochem.62: 2292-2299, 1994
9.
Potassium and calcium channels involvement in induction of long-lasting synaptic
enhancement by calyculin A, a protein phosphatase inhibitor, in rat hippocampal CA1
region.
Naoya Murakami, Norio Sakai, Koji Nei, Shogo Matsuyama, Naoaki Saito,
ChikakoTanaka
Neurosci-Lett. 176: 181-184, 1994
10.
Identification of putative 5-hydoxytryptamine4 receptors in guinea pig stomach: the effect
of TKS159, a novel agonist on gastric motility and acetylcholine release.
Shogo Matsuyama, Hideyo Sakiyama, Koji Nei and Chikako Tanaka
J. Pharmacol. Exp. Ther. 276: 989-995, 1996
11.
NMDA receptor activation induces glutamate release through nitric oxide synthesis in
guinea pig dentate gyrus.
Koji Nei, Shogo Matsuyama, Hisato Shuntoh and Chikako Tanaka
Brain Res. 728: 105-110, 1996
12.
Regulation of glutamate release via NMDA and 5-HT1A receptors in guinea pig dentate
gyrus.
Shogo Matsuyama, Koji Nei and Chikako Tanaka
Brain Res. 728: 175-180, 1996
13.
Regulation of GABA release via NMDA and 5-HT1A receptors in guinea pig dentate
gyrus.
Shogo Matsuyama, Koji Nei and Chikako Tanaka
Brain Res. 761: 105-112, 1997
14.
Long-term potentiation persistence greater in C57BL/6 than DBA/2 mice: predicted on
basis of protein kinase C levels and learning performance.
Shogo Matsuyama, Uk Namgung and Aryeh Routtenberg
Brain Res. 763: 127-130, 1997
15.
Long-term potentiation activates the GAP-43 promoter: selective participation of
hippocampal mossy cells.
Uk Namgung, Shogo Matsuyama and Aryeh Routtenberg
Proc. Natl. Acad. Sci. USA 94: 11675-11680, 1997
16.
A “LTP-like” facilitation of hippocampal synaptic transmission induced by the nootropic
nefiracetam.
Tomoyuki Nishizaki, Toshiyuki Matsuoka, Tamotsu Nomura, Shogo Matsuyama, Shigeo
Watabe, Tadashi Shiotani and Mitsunobu Yoshii
Brain Res. 826: 281-288, 1999
17.
Sustained facilitatory action of FK960 on hippocampal neurotransmission.
Shogo Matsuyama, Tamotsu Nomura, Tomoyuki Nishizaki
Brain Res. 857: 317-320, 2000
18.
Activation of nicotinic acetylcholine receptors induces long-term potentiation in vivo in
the intact mouse dentate gyrus.
Shogo Matsuyama, Akira Matsumoto, Taira Enomoto, Tomoyuki Nishizaki
Eur. J. Neurosci. 12: 3741-3747, 2000
19.
Mice with markedly reduced PACAP(PAC1) receptor expression by targeted deletion of
the signal peptide.
Hitoshi Hashimoto, Norihito Shintani, Akiko Nishino, Masaru Okabe, Masahito Ikawa,
Shogo Matsuyama, Kyoko Itoh, Kyohei Yamamoto, Shuhei Tomimoto, Takashi Fujita,
Nami Hagihara, Wakaba Mori, Yutaka Koyama, Toshio Matsuda, Shigekazu Nagata,
Akemichi Baba
J. Neurochem. 75: 1810-1817, 2000
20.
Human brain carboxypeptidase B, which cleaves -amyloid peptides in vitro, is
expressed in the endoplasmic reticulum of neurons.
Akira Matsumoto, Kyoko Itoh, Tsuneyoshi Seki, Kenjiro Motozaki, Shogo Matsuyama
Eur. J. Neurosci. 13: 1653-1657, 2001
21.
Critical role of presynaptic nicotinic ACh receptor in the formation of long-term
potentiation: implications for development of anti-dementia drugs.
Tomoyuki Nishizaki, Tamotsu Nomura, Shogo Matsuyama, Takeshi Kondoh, Etsuko
Fujimoto, Mitsunobu Yoshii
Psychogeriatrics 1: 209-217, 2001
22.
Brain-specific carboxypeptidase B: selective down-regulation in ependymal cell by
irradiation and altered -amyloid processing.
Tetsuya Kawabe, Ryohei Sasaki, Hideki Nishimura, Toshinori Soejima, Shogo
Matsuyama, Kazuro Sugimura, Akira Matsumoto
Neurosci. Res. Commun. 31: 75-84, 2002
23.
Expression and distribution of carboxypeptidase B in the hippocampal subregions of
normal and Alzheimer's disease brain.
Henrietta Papp, I. Torok, Akira Matsumoto, T. Enomoto, Shogo Matsuyama, Peter Kasa
Acta Biologica Hungarica 54(1): 55-62, 2003
24.
A neuron-specific EGF family protein, NELL2, promotes survival of neurons through
mitogen-activated protein kinases.
Masato Horie, Koutoku Aihara, Shun'ichi Kuroda, Norihiro Kanayama, Shogo Matsuyama,
Katsuyuki Tanizawa
Mol. Brain Res. 116: 86-93, 2003
25.
Impaired long-term potentiation in vivo in the dentate gyrus of pituitary adenylate
cyclase-activating polypeptide (PACAP) - or PACAP type 1 receptor-mutant mice.
Shogo Matsuyama, Akira Matsumoto, Hitoshi Hashimoto, Norihito Shintani, Akemichi
Baba
NeuroReport 14: 2095-2098, 2003
26.
Epibatidine induces LTP via activation of 42 nicotinic acetylcholine receptors
(nAChRs) in vivo in the intact mouse dentate gyrus: both 7 and 42 nAChRs essential
to LTPn.
Shogo Matsuyama, Akira Matsumoto
J. Pharmacol. Sci. 93(2): 180-187, 2003
27.
Enhanced long-term potentiation in vivo in dentate gyrus of NELL2-deficient mice.
Shogo Matsuyama, Koutoku Aihara, Naoki Nishino, Satoshi Takeda, Katsuyuki Tanizawa,
Shun’ichi Kuroda, Masato Horie
NeuroReport 15(3): 417-420, 2004
28.
Spatial learning of mice lacking a neuron-specific EGF family protein, NELL2.
Shogo Matsuyama, Nobuyuki Doe, Naoki Kurihara, Katsuyuki Tanizawa, Shun’ichi
Kuroda, Hiroyuki Iso, Masato Horie
J. Pharmacol. Sci. 98(3): 239-243, 2005
29.
Transgenic mice expressing mutant (N279K) human tau show mutation dependent
cognitive deficits without neurofibrillary tangle formation.
Taizo Taniguti, Nobutaka Doe, Shogo Matsuyama, Yoshihisa Kitamura, hiroshi Mori,
Naoaki Saito, Chikako Tanaka
FEBS Lett. 579: 5704-5712, 2005
30.
Inverse correlation between APP and synaptic plasticity in transgenic mice.
Shogo Matsuyama, Takami Tomiyama, Rie Teraoka, Hiroshi Mori
NeuroReport 18(10): 1083-1087, 2007
31.
Long-term potentiation-like facilitation through GABAA receptor blockade in the mouse
dentate gyrus in vivo.
Shogo Matsuyama, Taizo Taniguchi, Keiichi Kadoyama, Akira Matsumoto
NeuroReport 19(18): 1809-1813, 2008
32.
Quantitative analysis of beta-amyloid peptides expressed in human cerebrospinal fluid by
an improved method of antibody-assisted time-of-flight mass spectrometry.
Akira Matsumoto, Reiko Matsumoto, Kei-ichi Kadoyama, Taka-aki Nishimoto,
Shogo Matsuyama, Osamu Midorikawa
Int J Pept Res Ther 15(3): 205-210, 2009
33.
Disease-dependent reciprocal phosphorylation of serine and tyrosine residues of
c-Met/HGF receptor contributes disease retardation of a transgenic mouse model of
ALS.
Keiichi Kadoyama, Hiroshi Funakoshi, Wakana Ohya-Shimada, Takahiro Nakamura,
Kunio Matsumoto, Shogo Matsuyama, Toshikazu Nakamura
Neurosci Res 65: 194-200, 2009
34.
Use of a phoshophosensor dye in proteomic analysis of human mutant tau transgenic mice.
Masaoki Takano, Mieko Otani, Akiko Sakai, Keiichi Kadoyama, Shogo Matsuyama,
Akira Matsumoto, Mariko Takenokuchi, Miho Sumida, Taizo Taniguchi
NeuroReport 20: 1648-1653, 2009
35.
SJLB mice develop tauopathy-induced parkinsonism.
Mariko Takenokuchi, Keiichi Kadoyama, Shunmei Chiba, Miho Sumida,
Shogo Matsuyama, Katsuyasu Saigo, Taizo Taniguchi
Neurosci Lett 473: 182-185, 2010
36.
A mouse model of amyloid β oligomers: their contribution to synaptic alteration, abnormal
tau phosphorylation, glial activation, and neuronal loss in vivo.
Takami Tomiyama, Shogo Matsuyama, Hiroyuki Iso, Tomohiro Umeda, Hiroshi Takuma,
Kiyouhisa Ohnishi, Kenichi Ishibashi, Rie Teraoka, Naomi Sakama, Takenari Yamashita,
Kazuchika Nishitsuji, Kazuhiro Ito, Hiroyuki Shimada, Mary P. Lambert, William L.
Klein, Hiroshi Mori
J Neurosci 30(14): 4845-4856, 2010
37.
Synaptotagmin1 synthesis induced by synaptic plasticity in mouse hippocampus through
activation of nicotinic acetylcholine receptors.
Takaaki Nishimoto, Keiichi Kadoyama, Masaoki Takano, Mieko Otani, Yabin Lu,
Akira Matsumoto, Taizo Taniguchi, Shogo Matsuyama
Neurosci Lett 489: 25-29, 2011
38.
Phosophoproteome profiling using a fluorescent phosphosensor dye in two-dimensional
polyacrylamide gel electrophoresis.
Mieko Otani, Taizo Taniguchi, Akiko Sakai, Jouji Seta, Keiichi Kadoyama, Tooru
Nakamura-Hirota, Shogo Matsuyama, Keiji Sano, Masaoki Takano
Appl Biochem Biotechno l164(6): 804-818, 2011
39.
Proteomic analysis of the brain tissues from a transgenic mouse model of amyloid 
oligomers.
Masaoki Takano, Kouji Maekura, Mieko Otani, Keiji Sano, Tooru Nakamura-Hirota,
Shogo Tokuyama, Kyong Son Min, Takami Tomiyama, Hiroshi Mor, Shogo Matsuyama
Nerurochemistry International 61: 347-355, 2012
40.
The expression changes of EphA3 receptor during synaptic plasticity in mouse
hippocampus through activation of nicotinic acetylcholine receptor.
Tooru Nakamura-Hirota, Keiichi Kadoyama, Masaoki Takano, Mieko Otani, Shogo Matsuyama
NeuroReport 23:746-751, 2012
41.
Proteomic analysis of the hippocampus in Alzheimer’s disease model mice by using
two-dimensional fluorescence difference in gel electrophoresis.
Masaoki Takano, Takuya Yamashita, Kazuya Nagano, Mieko Otani, Kouji Maekura,
Haruhiko Kamada, Shin-ichi Tsunoda, Yasuo Tsutsumi, Takami Tomiyama, Hiroshi Mori,
Kenji Matsuura, Shogo Matsuyama
Neurosci Lett 534: 85-89, 2013
42.
Proteomic analysis of time-dependent changes in proteins expressed in mouse hippocampus
during synaptic plasticity induced by GABAA receptor blockade.
Kenji Matsuura, Tooru Nakamura-Hirota, Masaoki Takano, Mieko Otani, Keiichi
Kadoyama, Shogo Matsuyama
Neurosci Lett 555: 18-23, 2013
43.
Nuclear localization of bradykinin B2 receptors reflects binding to the nuclear envelope
protein lamin C.
Masaoki Takano, Akira Kanoh, Ayano Koike, Katsumi Amako, Mieko Otani, Keiji Sano,
Michiko Kanazawa-Hamada, Shogo Matsuyama
Eur J Pharmacol 723:507-514, 2014
44.
邦文
1.
GABAA 受容体アンタゴニストによる LTP 様作用の誘発
松山正剛
角山圭一
谷口泰造
生体の科学 60(5): 392-393, 2009
2.
EphA3 受容体とシナプス可塑性
松山正剛
角山圭一
松浦健二
生体の科学 64(5): 474-475, 2013
ニコチンによるマウス海馬シナプス可塑性発現下でのプロテオーム解析と CRMP-2 の発現変化
松山正剛、角山圭一、廣田徹、谷口泰造、鷹野正興
喫煙科学研究財団研究年報 392-393, 平成２３年度 査読無
ニコチンによるマウス海馬シナプス可塑性発現下での EphA3 受容体の発現変化 松山正剛、角山圭
一、松浦健二、谷口泰造、鷹野正興
喫煙科学研究財団研究年報 715-719, 平成２４年度
査読無
BOOK CHAPTERS（著書）
英文：
1.
Involvement of the g subtype of protein kinase C in GABA release from the cerebellum.
Kohtaro Taniyama, Naoaki Saito, Akiko Kose, Shogo Matsuyama, Shinji Nakayama and
Chikako Tanaka
The Biology and Medicine of Signal Transduction, edited by Yasutomi Nishizuka et al.
Raven Press, New York 399-404, 1990
2.
GABAergic Mechanisms and Cardiovascular Function.
Kohtaro Taniyama, Naoaki Saito, Shogo Matsuyama, Koichiro Takeda and Chikako
Tanaka
GABA OUTSIDE THE CNS, edited by Sandor L. Erdo
Springer-Verlag 261-268, 1991
3.
Expected therapeutic use of GABA agonists and antagonists for gut motility disorders.
K. Taniyama, M. Kusunoki, S. Matsuyama, K. Yamashita and M. Kaibara
GABA: Receptors, Transporters and Metabolism, edited by C. Tanaka and N. G. Bowery
Birkhäuser 307-312, 1995
4.
A2a adenosine receptor facilitates hippocampal neurotransmission by blocking glutamate
uptake via the glial glutamate transporter GLT-1.
T. Nishizaki, S. Matsuyama
Control and Diseases of Sodium Dependent Transport Proteins and Ion Channels, edited
by Y. Suketa, E. Carafoli, M. Lazdunski, K. Mikoshiba, Y. Okada, E.M. Wright
Elsevier 415-417, 2000
5.
Learning deficits in N279K tau transgenic mice and an assembly model of tau protein.
Taizo Taniguchi, Shogo Matsuyama, Katsuhiko Minoura, Hiroyuki Iso, Masahiro Sasaki,
Koji Tomoo, Toshimasa Ishida, Hiroshi Mori, Chikako Tanaka
Molecular Neurobiology of Alzheimer Disease and Related Disorders, edited by M.
Takeda, T. Tanaka and R. Cacabelos, Basel, Karger, 183-194, 2004
邦文：
１．自律神経の薬理 田中千賀子、松山正剛 P60-75
自律神経の基礎と臨床 後藤由夫、松尾裕、佐藤昭夫 編
医薬ジャーナル社 １９９３
２．遺伝子クローニング 松山正剛、久野高義
P4
病理学キーワード ‘97 病理と臨床 Vol.15 臨時増刊号 文光堂
REVIEWS（総説）
英文：
1.
Involvement of the -subtype of protein kinase C in GABA release from the cerbellum.
Kohtaro Taniyama, Naoaki Saito, Akiko Kose, Shogo Matsuyama, Shinji Nakayama,
Chikako Tanaka
Adv. Second Messenger and Phosphoprotein Res. 24: 399-404, 1990
2.
Intracellular and nuclear bradykinin B2 receptors
Masaoki Takano, Shogo Matsuyama
Eur J Pharmacol 732:169-172, 2014
邦文：
１．
佐野勇、竹田浩一郎、中山晋二、松山正剛、水野千佳、谷山紘太郎、田中千賀子
消化管運動とレセプタの役割
Ther. Res. 9: 333-341, 1988

症例の比較で学ぶ画像診断