植物の『運動』と『記憶』を制御する生理活性天然物の ケミカルバイオロジー

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2) P. SD;7_!T<2#[V.FK
FKON8*\+5A?(1996)
3) M.Ueda, S.Yamamura,: Angew. Chem. Int. Ed. 39, 1400-1414 (2000).
4) M. Ueda, Y. Nakamura, Natural Product Reports, 23, 548-557 (2006).
5) E. Kato, T. Sasaki, T. Kumagai and M. Ueda, Tetrahedron Lett., in press (2007).
6) M. Ueda and Y. Nakamura, Plant Cell Physiology, accepted (2007) .
7) Y. Nakamura, A. Matsubara, M. Okada, T. Kumagai, M. Ueda, Chemistry Letters, 35, 744-745 (2006).
8) Y. Asamitsu, Y. Nakamura, M. Ueda, S. Kuwahara, H. Kiyota, Chemistry and Biodiversity (Chem.
Biodivers.), 3, 654-659(2006).
9) Y. Nakamura, R. Miyatake, A. Matsubara, H. Kiyota, M. Ueda, Tetrahedron, 62, 8805-8813 (2006).
10) Y. Manabe, T. Sugimoto, T. Kawasaki, and M. Ueda, Tetrahedron Lett., in press (2007).
11) T. Fujii, Y. Manabe, T. Sugimoto, M. Ueda, Tetrahedron, 61, 7874-7893 (2005).
12) D;7_S.FKC&68,J) (1981).
13) $P 9=H^4:]%GQU>KWYM(/8`bB
3a52-57 (2005).