Systemic Lupus Erythematosus (SLE) Epidemiology In-depth Analysis to 2025

Systemic Lupus Erythematosus (SLE) Epidemiology In-depth
Analysis to 2025
“The Systemic Lupus Erythematosus (SLE) EpiCast Report provides an
overview of the risk factors, comorbidities, and global and historical trends of
SLE in the seven major markets (7MM) (US, France, Germany, Italy, Spain, UK,
and Japan).”
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of multifactorial origin that can affect any
organ or organ system, resulting in a broad spectrum of clinical manifestations ranging from dermatological
involvement to multi-organ failure with episodes of relapses and remissions.
Because of its dynamic nature, this disease has an unpredictable natural course leading to high rates of
morbidity and even death. The incidence and prevalence of SLE varies globally and the variation is attributed to
a combination of elements such as the characteristics of the population studied, sex, ethnicity, geographical
locations, occupational factors, familial traits, time of study, and the diagnostic criteria used.
In 2015, the 7MM had 475,698 diagnosed prevalent cases of SLE, for all ages, men and women combined. The
US accounted for approximately 53% of the diagnosed prevalent cases (253,215) in the 7MM. Epidemiologists
forecast that there will be 498,420 diagnosed prevalent cases of SLE in the 7MM by 2025, with an Annual Growth
Rate (AGR) of 0.48% during the forecast period. The diagnosed prevalent cases of SLE are projected to increase
in all markets, except for Germany and Japan, where there were slight decreases during the forecast period.
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The increase in the prevalent cases of SLE in the US and the UK are attributed to a forecast increase in SLE
prevalence over time and changes in the underlying population. Epidemiologists held the prevalence constant
for the remaining markets; thus any changes observed in the remaining markets are attributed to changes in
the population.
Epidemiologists utilized data from country-specific studies published in peer-reviewed journals and
governmental documents to provide the age- and sex-specific prevalence of diagnosed SLE in the respective
markets. The forecast methodology was consistent across all of the 7MM to allow for a meaningful comparison
among them.
Scope of this Report:
 The Systemic Lupus Erythematosus (SLE) EpiCast Report provides an overview of the risk factors,
comorbidities, and global and historical trends of SLE in the seven major markets (7MM) (US, France,
Germany, Italy, Spain, UK, and Japan). It includes a 10-year epidemiology forecast of diagnosed prevalent
cases of SLE (as per the 1997 revised American College of Rheumatology classification) segmented by sex,
age, and severity. This report also provides an epidemiological forecast of the diagnosed prevalent cases of
lupus nephritis (LN) among SLE patients for the 7MM, segmented into both 1995 WHO classifications (1985
for Japan) and 2003 ISN/RPS classifications.
 The SLE epidemiology report is written and developed by Masters- and PhD-level epidemiologists.
 The EpiCast Report is in-depth, high quality, transparent and market-driven, providing expert analysis of
disease trends in the 7MM.
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Reasons To Buy
1. Develop business strategies by understanding the trends shaping and driving the global SLE market.
2. Quantify patient populations in the global SLE market to improve product design, pricing, and launch
plans.
3. Organize sales and marketing efforts by identifying the age groups and sex that present the best
opportunities for SLE therapeutics in each of the markets covered.
4. Identify the percentage of diagnosed prevalent cases of SLE by severity.
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Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of multifactorial origin that can affect any organ or organ system, resulting in a broad spectrum of clinical manifestations ranging from dermatological involvement to multi-organ failure with episodes of relapses and remissions

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