Controlled-Release Drug Delivery Technology Market Dynamics, Segments and Supply Demand 2017-2027

Controlled-Release Drug Delivery Technology Market
March 2017
Report Id : REP-GB-2833
Status : Ongoing
Category : Healthcare, Pharmaceuticals & Medical Devices
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Controlled-Release Drug Delivery Technology Market Analysis
Specific focus on the quality-by-design (QbD) approaches for the robust design of dosage forms is
expected to change the future landscape of controlled-release drug delivery technologies. While
conventional hydrophilic matrix based technologies such as Accuform are being used in the market for
several years, recent advancements in the development of oral drug delivery systems such as gastroretentive drug delivery for controlled release, buoyant systems, mucoadhesive systems for regulated
release of anti-viral medications etc. would increase the penetration of controlled-release drug delivery
technologies in the global pharmaceuticals market. Acuform polymer-based patented technology is
widely being used in a number of controlled-release formulations such as NUCYNTA ER, Gralise
(Depomed Inc.), Janumet XR (Merck), Glumetza (Salix Pharmaceuticals) etc. Wurster coating technology is
being used in the drug coating for controlled release of drug since 1976. Corplex transdermal technology
has largely been commercialized in P&G’s Crest product line. Plenty of new controlled-release
technologies are in phase to be commercialized in next few years. For instance, MicroCor PTH using
MicroCor transdermal technology is being evaluated in phase IIa. OROS technology which delivers drug
in controlled manneris being used in more than 17 commercially available drugs. In case of oral
controlled drug delivery, elderly persons and pediatrics constitute the large proportion of consumers for
controlled-release drugs due to increase adherence to dosage regime. Some of the commercially
available medications using controlled-release drug delivery technology include Prozac (polymer matrix
based system), Avinza (polymer coating), Capoten (enzyme activated system), GLUCOPHAGE XR (polymer
matrix based system), Alza (osmotically activated system) etc.
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Controlled-Release Drug Delivery Technology Market Analysis
Controlled-Release Drug Delivery Technology Market: Drivers and Restraints
The global market for controlled-release drug delivery technology is driven by increasing the need for
pediatric controlled release dosage forms, high acceptance of CR dosage forms due to once-a-daily
dosing nature, etc. However, some of the major factors restraining the global market for controlledrelease drug delivery technology are fewer excipients are deemed acceptable for pediatric use, the
requirement of a high dose of API, promising development of CR dosage forms that impart abuse
resistance, a higher price of controlled-release systems compared with traditional pharmaceutical
formulations, etc. Moreover, some of the biopharmaceutical challenges for development of controlledrelease drug delivery systems such as establishing desired release profiles for new chemical entities, risk
management of dose dumping, selection of biocompatible and biodegradable materials with desired
controlled-release properties, etc.
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Controlled-Release Drug Delivery Technology Market: Segmentation
The global controlled-release drug delivery technology market has been segmented on the basis of
technology, release mechanism, application, and geography.
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Controlled-Release Drug Delivery Technology Market Analysis
Based on technology, the global controlled-release drug delivery technology market is divided into
following:
 Wurster technique (drug coating)
 Coacervation
 Micro Encapsulation
 Implants
 Transdermal
 Targeted Delivery
 Microelectromechanical Technology
 Others (Liposomes)
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Controlled-Release Drug Delivery Technology Market Analysis
 Based on release mechanism, the global controlled-release drug delivery technology market is divided
into following:
 Polymer Coating Systems
 Polymer Matrix Based Systems

Hydrophilic Polymer Matrix Systems

Lipophilic Polymer Matrix Systems
 Micro Reservoir Partition Controlled Drug Delivery Systems
 Feedback Regulated Drug Delivery Systems
 Activation-modulated Drug Delivery Systems
 Mechanically Activated

Osmotic Pressure Activated

Hydrodynamic Pressure Activate
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Controlled-Release Drug Delivery Technology Market Analysis
 Vapor Pressure Activated
 Mechanically Activated
 Magnetically Activated

Chemically Activated
 pH Activated
 Hydrolysis Activated
 Enzyme Activated
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 Based on application, the global controlled-release drug delivery technology market is segmented as
below:
 Metered Dose Inhalers
 Injectable
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Controlled-Release Drug Delivery Technology Market Analysis
 Transdermal and Ocular Patches
 Infusion Pumps
 Oral Controlled-drug delivery Systems
 Drug Eluting Stents
 Others
Controlled-Release Drug Delivery Technology Market: Overview
The global market for controlled drug delivery technology is expected to gain traction during the forecast
period due to increasing commercialization of new technologies by a number of modified release
products launches. Loss of patents for some of the controlled-release drug delivery technologies would
present an opportunity for generic players to penetrate the market. For instance, blockbuster osmotic
delivery system OROS would be off patented by July 2017 and the technology will lose the pediatric
exclusivity by January 2018. Allergan Plc. received FDA approval for Generic Cardizem extended release
tablets indicated for the treatment of hypertension.
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Controlled-Release Drug Delivery Technology Market Analysis
Controlled-Release Drug Delivery Technology Market: Regional Wise Outlook
Geographically, the global controlled-release drug delivery technology market is classified into regions
viz. North America, Latin America, Western Europe, Eastern Europe, Asia-Pacific, Japan, Middle East and
Africa. North America will continue to hold the largest share in the global controlled-release drug delivery
technology market due to rising number of NDA and ANDA applications being filed by the key players.
Europe is expected to hold second largest share in the global market for controlled-release drug delivery
technology market. However, APAC is expected to witness highest growth rate due to expansion activities
by the key players in the region.
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Controlled-Release Drug Delivery Technology Market: Key Players
Some of the market players in the global controlled-release drug delivery technology market are
Depomed, Inc., Coating Place, Inc., Corium International Inc., Alza Corporation (Johnson & Johnson),
Pfizer Inc., SKY Pharmaceuticals Pvt. Ltd. and others. Global pharmaceutical companies are desperately
looking for new strategies to increase profitability and in line with this number of companies are
bringing in the market, the modified release formulations of existing drugs due to short pathway for
approval while maintaining their market share.
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Future Market Insights has announced the addition of the “Controlled-Release Drug Delivery Technology Market: Global Industry Analysis and Opportunity Assessment 2017-2027" report to their offering.