NF-kB Inhibitors Therapeutics - Pipeline Analysis, Research Report, 2017

Nuclear factor-kappa B (NF-kB) Inhibitors
Therapeutics Pipeline Projects Vast Growth
Ahead
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Nuclear factor-kappa B (NF-kB)
NF-kB inhibitors therapeutics pipeline in 2017
The study analyzed that the NF-kB inhibitors therapeutics pipeline comprises
approximately 17 drug candidates in different stages of development. Nuclear
factor-kappa B (NF-kB) is the transcription factor which is involved in the
regulation of over 500 genes, that are responsible for cell proliferation, survival,
invasion, metastasis, angiogenesis and inflammation. Therefore, development
of therapeutics that acts as NF-kB inhibitors, can treat various diseases
including cancer and chronic inflammation.
Access Report Summary with Detailed TOC on "Nuclear factor-kappa B (NF-kB)
Inhibitors Therapeutics Pipeline Analysis, 2017 - Clinical Trials & Results, Patent,
Designation,
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Nuclear factor-kappa B (NF-kB)
Insights on procedure segments
According to the research findings, most of the drug candidates in the NFkB inhibitors therapeutics pipeline are being developed as small molecule
using synthetic source.
Increasing prevalence of cancer drives the growth
of NF-kB inhibitors drug development
According to the National Cancer Institute, the prevalence of cancer has
been increasing at a very high rate. Therefore, companies are focusing on
developing target specific and personalized medicine for the better
treatment with reduced adverse events. Thus, NF-kB inhibitors therapeutics
pipeline is likely to grow significantly, in the future, for the treatment of
various diseases including cancer and chronic inflammation.
Nuclear factor-kappa B (NF-kB)
Various collaborations for NF-kB inhibitors drug
development
In May 2014, AnGes MG, Inc. and Shionogi & Co., Ltd. entered in a license
agreement to co-develop NF-kB decoy oligodeoxynucleotide for the
treatment of atopic dermatitis.
Some of the key players developing drugs as NF-kB inhibitors for the
treatment of various indications include Alkermes Plc, Reata
Pharmaceuticals, Inc., Incuron LLC, Catabasis Pharmaceuticals, Inc. and
others.
Nuclear factor-kappa B (NF-kB)
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The study analyzed that the NF-kB inhibitors therapeutics pipeline comprises approximately 17 drug candidates in different stages of development.