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Lysosomal Acid Lipase Deficiency Treatment Market Expected To Hit High CAGR By 2026

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Lysosomal acid lipase (LAL) deficiency is a rare inherited condition in which the body is not able to produce enough lysosomal acid lipase (LAL) enzyme, which is an important enzyme for breakdown of fatty materials namely cholesteryl esters and trig
Lysosomal
Acid
Lipase
(LAL)
Deficiency
Treatment Market Size, Share, Trend, Outlook,
Future Growth Analysis And Synthesis By 2026
Lysosomal acid lipase (LAL) deficiency is a rare inherited condition in which the body is not able to
produce enough lysosomal acid lipase (LAL) enzyme, which is an important enzyme for breakdown of
fatty materials namely cholesteryl esters and triglycerides. This results in building up of a large amount
of fatty material in body organs, which include spleen, liver, and gut. The deficiency of LAL causes two
autosomal recessive disorders, Wolman disease (WD) and Cholesteryl Ester Storage Disease (CESD). LAL
deficiency is caused due to the genetic mutation in LIPA gene, which results in decrease or loss of
Lysosomal Acid Lipase (LAL) enzyme.
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FDA approval of innovative drugs is expected to fuel the growth of Lysosomal Acid Lipase (LAL)
Deficiency Treatment Market
The approval of innovative drugs by Food and Drug Administration (FDA) is expected to augment the
growth of market. In 2015 the U.S. Food and Drug Administration (FDA) approved Alexion
Pharmaceutical’s Kanuma (sebelipase alfa), an innovative enzyme replacement therapy (ERT). Kanuma is
first approved therapy that treats the underlying cause of the disease. It is the only therapy for the
treatment of LAL deficiency. As it is the only available therapy in market, kanuma is expected to have a
significant market growth in the near future. According to the National Institute for Health and Care
Excellence (NICE) 2016, around 50% of patients suffering from lysosomal acid lipase (LAL) deficiency
have chances of liver complications, which includes cirrhosis or fibrosis and liver transplant. The
increasing incidences of liver complications due to LAL deficiency is expected to increase demand for
liver transplant, in turn fueling the growth of LAL deficiency treatment market over the forecast period.
High cost and lack of awareness about diagnosis and treatment among people is the major restraint for
the growth of Lysosomal Acid Lipase (LAL) Deficiency treatment market.
North America is expected to dominate market due to rapid novel innovations
Global market for the Lysosomal Acid Lipase (LAL) deficiency treatment market by Coherent
Market Insights is segmented into North America, Latin America, Europe, Asia Pacific, Middle
East, and Africa. North America is expected to dominate the lysosomal acid lipase (LAL)
deficiency treatment market attributed to rapid novel innovations, drug development, and
research. In 2015, FDA approved genetically modified organisms (GMO) chickens, for the
production of a recombinant human lysosomal acid lipase (LAL) protein in their eggs for the
treatment of lysosomal acid lipase (LAL) deficiency among Americans. Europe is expected to be
the second largest region for LAL deficiency treatment market. The Europe commission in 2015
granted marketing permission of Kanuma, for the treatment of LAL deficiency for patients of all
ages, which is expected to fuel the growth of kanuma in region.
Report includes chapters which deeply display the following deliverable about industry :
• Lysosomal Acid Lipase (LAL) Deficiency Treatment Market Research Objective and Assumption
• Lysosomal Acid Lipase (LAL) Deficiency Treatment Market Purview - Report Description,
Executive Summary, and Coherent Opportunity Map (COM)
• Lysosomal Acid Lipase (LAL) Deficiency Treatment Market Dynamics, Regulations, and Trends
Analysis - Market Dynamics, Regulatory Scenario, Industry Trend, Merger and Acquisitions, New
system Launch/Approvals, Value Chain Analysis, Porter’s Analysis, and PEST Analysis
• Global Lysosomal Acid Lipase (LAL) Deficiency Treatment Market, By Regions
• Lysosomal Acid Lipase (LAL) Deficiency Treatment Market Competition by Manufacturers
including Production, Share, Revenue, Average Price, Manufacturing Base Distribution, Sales
Area and Product Type.
• Lysosomal Acid Lipase (LAL) Deficiency Treatment Market Manufacturers Profiles/Analysis
including Company Basic Information, Manufacturing Base and Its Competitors.
• Lysosomal Acid Lipase (LAL) Deficiency Treatment Market Manufacturing Cost Analysis
including Key Raw Materials and Key Suppliers of Raw Materials.
• Industrial Chain, Sourcing Strategy and Downstream Buyers including Upstream Raw Materials
Sourcing and Downstream Buyers
• Marketing Strategy Analysis, Distributors/Traders including Marketing Channel, Market
Positioning and Distributors/Traders List.
• Market Effect Factors Analysis including Technology Progress/Risk, Consumer Needs/Customer
Preference Change and Economic/Political Environmental Change.
• Lysosomal Acid Lipase (LAL) Deficiency Treatment Market Forecast including Production,
Consumption, Import and Export Forecast by Type, Applications and Region.
• Research Findings and Conclusion
Rapid approval of therapy by FDA in various region, be an opportunities for companies
Ltd. In 2015, FDA approved Kanuma, an innovative enzyme replacement therapy (ERT) in the U.S.,
Europe Union, and Japan, which is providing an opportunity to manufacturers for exploring their
business in the untapped market. Major players operating in global Lysosomal Acid Lipase (LAL)
Deficiency treatment market include Alexion Pharmaceutical Inc., Merck & Co., Inc., Pfizer, Inc., and
AstraZeneca plc. and Teva Pharmaceutical Industries.
Lysosomal Acid Lipase (LAL) Deficiency Treatment Market Taxonomy:
The global Lysosomal Acid Lipase (LAL) deficiency treatment market is segmented on the basis of disease
type, treatment type, and end user.
On The Basis Of Disease Type:
•
Wolman Disease
•
Cholesteryl Ester Storage Disease (CESD)
On The Basis Of Treatment Type:
•
Liver Transplant
•
Hematopoietic Stem Cell Transplant
Browse In-Depth Analysis Research Report @ https://www.coherentmarketinsights.com/ongoinginsight/lysosomal-acid-lipase-deficiency-treatment-market-904
About Coherent Market Insights
Coherent Market Insights is a prominent market research and consulting firm offering actionready syndicated research reports, custom market analysis, consulting services, and competitive
analysis through various recommendations related to emerging market trends, technologies, and
potential absolute dollar opportunity.
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Author
Poul Master
Poul Master247   documents Email
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