Pertuzumab Market

Pertuzumab Market - Size, Share, Outlook, and
Opportunity Analysis 2018 – 2026
Pertuzumab is a recombinant monoclonal antibody that acts as an antineoplastic agent, which
targets the human epidermal growth factor receptor 2 protein known as HER2. The drug blocks
signaling pathways that leads to cell growth arrest and apoptosis (cell destruction), thereby
inhibiting the proliferation of human tumor cells. Pertuzumab was found to aid in the treatment
of HER2 associated breast cancer and was developed by Genentech, Inc., a subsidiary of F.
Hoffmann-La Roche AG. It was first approved by U.S. Food and Drug Administration in 2012.
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Pertuzumab Market– Drivers
There are increasing number of clinical trials for use of pertuzumab in combination with other
drugs for the treatment of breast cancer . For instance, Helsinki University Central Hospital is
undergoing phase III clinical study for adjuvant trastuzumab, pertuzumab, and docetaxel in the
treatment of early HER2 positive breast cancer. The study was started in December 2015 and is
estimated to complete by June 2023.
Furthermore, increasing number of drug approvals are expected to propel growth of the global
pertuzumab market. For instance, in December 2017, the U.S. Food and Drug Administration
(U.S FDA) granted approval to PERJETA, a pertuzumab produced by Genentech, Inc. for its use
in combination with trastuzumab and chemotherapy as adjuvant treatment of patients with
HER2-positive early breast cancer at high risk of recurrence.
Moreover, development of novel anticancer drug delivery technologies is expected to boost
growth of the market. For instance, in July 2018, Gentech, Inc., in partnership with Halozyme
Therapeutics, Inc., used proprietary ENHANZE drug-delivery technology of Halozyme
Therapeutics, Inc., for subcutaneous administration of fixed-dose combination of pertuzumab
(PERJETA) and trastuzumab (Herceptin). This study is under clinical phase III trial. ENHANZE
technology aids in reducing the need for multiple injections and reduces time required for drug
administration.
Report includes chapters which deeply display the following deliverable about industry :
• Pertuzumab Market Research Objective and Assumption
• Pertuzumab Market Purview - Report Description, Executive Summary, and Coherent
Opportunity Map (COM)
• Pertuzumab Market Dynamics, Regulations, and Trends Analysis - Market Dynamics,
Regulatory Scenario, Industry Trend, Merger and Acquisitions, New system Launch/Approvals,
Value Chain Analysis, Porter’s Analysis, and PEST Analysis
• Global Pertuzumab Market , By Regions
• Pertuzumab Market Competition by Manufacturers including Production, Share, Revenue,
Average Price, Manufacturing Base Distribution, Sales Area and Product Type.
• Pertuzumab Market Manufacturers Profiles/Analysis including Company Basic Information,
Manufacturing Base and Its Competitors.
• Pertuzumab Market Manufacturing Cost Analysis including Key Raw Materials and Key
Suppliers of Raw Materials.
• Industrial Chain, Sourcing Strategy and Downstream Buyers including Upstream Raw Materials
Sourcing and Downstream Buyers
• Marketing Strategy Analysis, Distributors/Traders including Marketing Channel, Market
Positioning and Distributors/Traders List.
• Market Effect Factors Analysis including Technology Progress/Risk, Consumer Needs/Customer
Preference Change and Economic/Political Environmental Change.
• Pertuzumab Market Forecast including Production, Consumption, Import and Export Forecast
by Type, Applications and Region.
• Research Findings and Conclusion
Pertuzumab Market– Restraint
Increasing cost of anticancer drugs is expected to be a major factor hampering growth of the
market. For instance, in June 2017, The Scottish Medicines Consortium (SMC) denied access to
pertuzumab in England, which was available via the Cancer Drugs Fund (CDF) in Europe. The
drug was rejected by SMC as the treatment of HER2 positive breast cancer was not cost
effective when pertuzumab was used in combination with trastuzumab and docetaxel.
Moreover, according to a study published in the journal Oncology, September 2015, although
the use of pertuzumab with docetaxel and trastuzumab as first-line therapy for HER2 positive
breast cancer has been shown to yield a substantial survival benefit, the therapy is not cost
effective in the U.S. Also, according to the same source, the cost of treating HER2 positive
breast cancer with pertuzumab and other drugs is US$ 509,845 and that with only docetaxel
and trastuzumab is US$ 135,092.
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Pertuzumab Market– Regional Analysis
On the basis of region, the global pertuzumab market is segmented into North America, Latin
America, Europe, Asia Pacific, Middle East, and Africa.
North America is expected to hold dominant position in the global pertuzumab market due to
increasing prevalence of breast cancer among women in the U.S. For instance, according to
American Cancer Society 2017, around 52,710 new cases of invasive breast cancer were
diagnosed in 2017 among women in the U.S. and around 40,610 women were expected to die
due to breast cancer in the U.S. in same year.
Furthermore, Asia Pacific is expected to witness significant growth in the global pertuzumab
market, owing to increasing awareness of breast cancer and its management. For instance, in
November 2016, India launched National Cancer Screening Program to increase awareness and
early detection of breast cancer. This framework aims to offer mechanism for effective screening
and management of common cancers.
Pertuzumab market – Competitive Analysis
Key players operating in the global pertuzumab market include, Halozyme Therapeutics, Inc.
and F. Hoffmann-La Roche Ltd.
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Pertuzumab is a recombinant monoclonal antibody that acts as an antineoplastic agent, which targets the human epidermal growth factor receptor 2 protein known as HER2.