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Humanized Liver Mice Model Market Global Trends, Market Share, Industry Size, Growth, Opportunities, and Market Forecast 2019 to 2029

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Global humanized liver mice model market to value over USD 115 Million by 2029 end and register a CAGR of over 5.5% from 2019 to 2029. Humanized mice models are mice that perform human functioning due to the presence of similar genes. Humanized mice
Humanized Liver Mice Model Market Global Trends, Market Share, Industry Size,
Growth, Opportunities, and Market Forecast 2019 to 2029
Global humanized liver mice model market to value over USD 115 Million by 2029
end and register a CAGR of over 5.5% from 2019 to 2029.
Humanized mice models are mice that perform human functioning due to the
presence of similar genes. Humanized mice models can be attained, through gene
modification and replacement.
Extensive research efforts are focused on developing efficient and new humanized
liver mice models. Initially, using simple immune-deficient methods were employed,
and mice were implanted with human liver cells or hepatic cancer cells. However, the
results were not as desired and consistent. The unreliability of the process led to the
discovery of immune-deficient mice that naturally annihilate the mice liver allowing
the human liver cells to grow and replace to form stable humanized liver mice
models. For instance, a number of studies are exploring the use of PPARalfa and
AFC8-based mice models for the development of a humanized liver mice model.
Another humanized liver mice model known as the hPXR/CAR/CYP3A4/ 2D6/2C9
mouse has 33 mouse genes replaced with human genetic counterparts. Furthermore,
with the improvement in medical science and genetic technology, the scope of
developing new genetically engineered humanized liver mice models has widened.
The invention of CRISPR technology is one such instance.
The approval of numerous liver disease-associated drugs by the FDA has also
promoted the growth of the market and encouraged research and development. The
high expenses of humanized liver mice are projected to restrain the growth of the
market. For instance, the immune-deficient mice used for liver studies through
grafting are available in the range of US$ 140–500, whereas chimeric humanized liver
mice with 75–90% of human hepatocyte replacement, cost about US$ 2500–3500. In
addition, since these are specifically genetically modified species, the shipping costs
are also significantly higher along with the special containers and facility provided
during the transportation, these overheads invariably increase the overheads.
Replace, reduce and refine is the policy followed in animal studies. It provides a
framework for humane research. Replacement of animal models allows the use of
alternatives such as 2D & 3D cell lines and is recommended to reduce the number of
animals. The aim behind this is to minimize animal suffering without compromising
on the statistics of the experiment or research.
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By Application
● Pharmacokinetics Studies
● In-vivo Liver Toxicity Testing
● Drug Metabolism Studies
● Others
By Model
● uPA-SCID
● FRG KO Mice
● TK-NOG Mice
● Other Models
By End User
● Pharmaceutical Companies
● Biotechnology Companies
● Contract Research Organizations (CRO’s)
● Academic & Research Institutes
By Region:
● Europe
● North America
● APAC
● Latin America
● Rest of World
The market of North America garners the maximum revenue and is expected to grow
at the highest CAGR during the forecast period.
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Competitive Landscape:
● Tier 1 players- established companies in the market with a major market share
● Tier 2 players
● Emerging players which are growing rapidly
● New Entrants
Major market influencers include Yecuris Corporation, PhoenixBio Group, Beijing
Vitalstar Biotechnology Co. Ltd., Hera BioLabs, Taconic Biosciences, Inc., University
of Massachusetts Medical School, Oncodesign, University of Nebraska Medical
Center and Jackson Laboratory.
FutureWise Key Takeaways
● Growth prospects
● SWOT analysis
● Key trends
● Key data points affecting market growth
Objectives of the Study:
● To provide an exhaustive analysis on the humanized liver mice model based on
application, model, end user and region
● To cater comprehensive information on factors impacting market growth
(drivers, restraints, opportunities, and industry-specific restraints)
● To evaluate and forecast micro-markets and overall market
● To predict the market size, in key regions (along with countries)—North America,
Europe, Asia Pacific, Latin America, and the Middle East and Africa
● To record evaluate and competitive landscape mapping- product launches,
technological advancements, mergers and expansions
● Profiling of companies to evaluate their market shares, strategies, financials and
core competencies
Inquire further details about this report at: [email protected]
About FutureWise Research:
We specialise in high-growth niche markets, assuring flexibility, agility and
customised solutions for our clients. Through in-depth market insights and
consultancy, we present our clients with the tools they need to be at the forefront of
their industry – a position secured for far more than the near future.
Contact Us:
Company Name: FutureWise Research
Contact Person: Vinay Thaploo
Email: [email protected]
Phone: +44 141 628 9353 / +1 970 279 4295
City: Leeds
Country: United Kingdom
Website: www.futurewiseresearch.com
Author
Merin John
Merin John263   documents Email
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