"A STUDY TO ASSESS THE EFFECTIVENESS OF STRUCTURED TEACHING PROGRAMME ON KNOWLED REGARDING PROTECTIVE EFFECT OF BILINGUALISM ON ALZHEIMERS DISEASE AMONG MONOLINGUAL ADULTS BETWEEN THE AGES OF 35-50 YEARS AT SELECTED RURAL COMMUNITIE AT TUMKUR" PROFORMA FOR REGISTRATION OF SUBJECT FOR THE DISSERTATION SUBMITTED BY MISS MINU VARGHESE MENTAL HEALTH PSYCHIATRIC NURSING 2011-2013 SRI SIDDARTHA COLLEGE OF NURSING AGALAKOTE, B.H. ROAD TUMKUR RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES, BANGALORE, KARNATAKA PROFORMA FOR REGISTRATION OF SUBJECT FOR DISSERTATION 1 NAME OF THE CANDIDATE & ADDRESS MISS MINU VARGHESE I YEAR M.Sc. NURSING SRI SIDDARTHA COLLEGE OF NURSING AGALAKOTE,TUMKUR 2 NAME OF THE INSTITUTION SRI SIDDARTHA COLLEGE OF NURSING, B.H ROAD,TUMKUR 3 COURSE OF THE STUDY& SUBJECT MASTER OF SCIENCE IN NURSING MENTAL HEALTH PSYCHIATRIC NURSING 4 DATE OF ADMISSION 6th JULY 2011 5 TITLE OF THE TOPIC "A 2 STUDY TO ASSESS THE EFFECTIVENESS OF STRUCTURED TEACHING PROGRAMME ON KNOWLEDGE REGARDING PROTECTIVE EFFECT OF BILINGUALISM ON ALZHEIMERS DISEASE AMONG MONOLINGUAL ADULTS BETWEEN THE AGE GROUP OF 35-50 YEARS AT SELECTED RURAL COMMUNITIES IN TUMKUR” BRIEF RESUME OF THE INTENDED WORK 6. INTRODUCTION “Language exerts hidden power, like a moon on the tides” RitaMae Brown Despite the past century’s fascination with measuring every facet of life ‘little is known about the middle years (age between35-50 years).After all, living in to middle age is a relatively recent phenomenon in human history. Although the pressing nature of agerelated ill health precipitated a welcome and much needed boom in information about aging, there reunited a paucity of knowledge about the middle years1. Alzheimer’s disease was first described by a German Psychiatrist and Neurologist, Dr Aloes -Alzheimer, in 1906, on a middle- aged patient suffering from Dementia. It was after the death of the patient, by autopsy, that Alzheimer was able to demonstrate abnormal changes in the brain. Alzheimer’s disease (AD) is also called the death of mind. The AD is cruel disease which not only destroys person’s mind but also robs him or her of memories. It is a progressive degenerative disease which attacks the tissues of the brain and results in impaired memory, thinking, behaviour and emotions. The process is gradual and is often associated with loss of the individual’s ability to care for him or herself2. 3 Bilingualism is an intriguing field Researchers across the world are racing towards a cure for Alzheimer’s disease. As prevalence rates climb, their focus has broadened from treatment to prevention strategies. Although there are no magic solutions, tantalizing new evidence suggests it may be possible to prevent or delay the onset of Alzheimer’s disease through a combination of healthful habits. Scientists with the Rot man Research Institute at the Bay crest Research Centre for Aging and the Brain have found the first evidence that another lifestyle factor, bilingualism, may help delay AD symptoms3. Due to globalization and multiculturalism, the world has seen a rapid increase of bilingual or multilingual speakers. Throughout the world people have grasped the importance of acquiring a second or third foreign language, indicates that there are more bilingual people in the world than there are monolingual people4. Since the mid-twentieth century, bilingualism has been offering a broad spectrum of research possibilities. For instance, the positive influence of bilingualism on children and the correlation between bilingualism and cognitive decline have already been examined5. Over the last decades, Ellen Bialystok, a research professor of psychology at York University in Toronto, has proven to be a pioneer in this field of study. They examined the effect of lifelong bilingualism on the onset of symptoms of AD. Results showed that bilingualism has a protective effect in delaying the onset of AD by four years6. The term of ‘bilingualism’, - and that of ‘multilingualism’, too - is used frequently. “bilingualism is the ability to use two or more languages sufficiently to carry 4 on a limited casual conversation”. They believe that the interpretation of bilingualism may differ from one individual to another .It indicates that there are at least twenty dimensions of language to determine whether a person is bilingual7. When the people have acquired a minimum level of competences, such as reading, writing and speaking, in a foreign language, they will be bilingual8. Bilingualism is an intriguing field of study for many researchers. There are “two intrinsic values in studying bilingualism”. First, “studying bilingualism tells us something about the genetic potential of humans”. Second, “simply living in a community where two or more languages are spoken is a part of the human experience”9. Thus, the status of languages spoken within the community is an important factor in studying bilingualism. The possible benefits of bilingualism have raised many questions during the latter half of the twentieth century. Until the 1950s, researchers mainly focused on behavioural consequences of bilingualism. Later, the cognitive implications of bilingualism were considered. Peal and Lambert were the first to establish the positive effects of bilingualism10. Later on various studies have clearly indicated that bilingualism has positive effect on cognitive function. The objective of this dissertation is to give an insight regarding these new areas of studies as well as encourage monolingual adult for learning a new language to fight with AD. 5 6.1 NEED FOR STUDY Over the past 50 years careful research was able to show that Alzheimer’s disease occurs more commonly in the elderly than in those in middle age. It affects 5-10 % of those over 65 years of age and more than 20 % of those over 80 years. As the proportion of people over 65 years is gradually increasing more cases of AD will accumulate and it may turn in to a greater public health problem. In the USA and other western countries AD has become the 4th leading cause of death (after heart diseases, cancer and stroke) among adults around the age of 75. AD is becoming a problem in developing countries as well. Even a 2-year delay in onset of Alzheimer’s disease (AD) would reduce the prevalence in the USA by 1.94 million after 50 years, and delays as short as 6 months could have substantial public health implications11. Many of the factors predisposing a person to AD are biological. So the search for methods to delay onset has focused largely on pharmacological and other biologically-based therapies12.There is growing evidence, however, that some environmental factors can maintain cognitive functioning in older adults and mitigate the effects of illnesses that produce AD.Notably,research on“cognitive reserve” has demonstrated that lifestyle factors, such as physical activity, stimulating leisure involvement, and social engagement play a role in post ponding the onset of AD and other dementias. The report, released in September 2009 by Alzheimer's disease International, says more than 35 million people worldwide have Alzheimer's disease or other types of 6 dementia, according to the most in-depth attempt yet to assess the brain-destroying illness. The updated count is about 10 per cent higher than predicted just a few years ago, because earlier research underestimated Alzheimer's growing impact in developing countries. Barring a medical breakthrough, dementia will nearly double every 20 years. By 2050, it will affect 115.4 million people, the report suggests. Alzheimer's is the most common form of dementia and affects one in 20 Canadians over 65 — about 290,000 people. The number rises to one in four in those over 85. Close to 75 per cent of Canadians with Alzheimer's are women. According to researchers at the Johns Hopkins Bloomberg School of Public Health in Baltimore, by 2050 the number of cases around the world will quadruple to around 106 million people. '71,000 Canadians under the age of 65 are living with Alzheimer's disease or a related dementia. Approximately 50,000 are 59 or younger13. The overall notion is that some factors allow a person to function within a normal cognitive range, despite the presence of brain pathology that would usually be associated with dementia. For example, Mortimer (1997) found that between 10 and 40% of autopsy cases -showing brain pathology exceeding the criteria for AD had shown no signs of cognitive impairment before death. Similarly a population-based study carried out by the UK Medical Research Council found that more than 30% of individuals with mild and severe AD pathology at autopsy had shown no previous signs of cognitive impairment14. Importantly, most of the studies included in the review found significant effects of the protective variable in question after co-varying out age and other brain-reserve 7 measures. One surprising conclusion of the review was that “it is evident that mentally stimulating leisure activity is the most robust brain-reserve measure, since all these studies showed a significant protective effect even after controlling for age, education, occupation and other potential confounds” 13 .They found an overall decrease in incident dementia of 46% after a median follow-up interval of 7.1 years; these figures are based on a total of over 29,000 individuals from 22 studies. It is important to note the authors’ caution that higher levels of behavioural brain reserve may simply delay the onset of dementia, rather than reduce incidence in an absolute manner. In a comparison piece, the same authors conducted a review of studies of longitudinal cognitive change and factors ameliorating cognitive decline in the elderly14. This second review was based on a new sample of 18 studies involving more than 47,000 individuals; the main finding was that higher levels of behavioural brain reserve were related to decreased rates of cognitive decline. A longitudinal study was conducted on 2004, also found strong evidence for the role of social, mental, and physical activities in protecting against all types of dementia. Similarly, they concluded that “more education and a more cognitively complex occupation predict higher cognitive ability in old age than would be expected for a person’s childhood ability and accumulated brain burden”15. According to the 1981 Census, out of a total population of 685.2 million, in the world, 44 million people were aged 60 years and over. In the 1991 census the number of elderly was about 55.3 million, that is, 6% of the total population of 844.3 million. The 8 number of people over 60 years is expected to touch the 60 million mark by the end of this century. Although there is no exact figure of AD patients in India, recent surveys in south India report that the rate of Dementia of the people over 60 years varied from 2.7% to3.4%, a figure almost identical to the western countries16. From these reviews, it seems clear that the prevalence rate of AD is rising gradually as well as the complex mental activity across the lifespan can acts to at least delay the incidence of Alzheimer’s. So it is essential to find out the types of mental activity yield this protective function as well as the mechanism linking mental activity to its neuroprotective function. The recent report contributes some solution for this by demonstrating a further type of mental activity that may be associated with a delay in the appearance of the symptoms of dementia and Alzheimer’s. The activity in question is the constant use of two languages over many years; Bilingualism has been shown to enhance attention and cognitive control in both children17 and older adults18. In these studies, lifelong bilinguals who use both languages in their daily lives showed an advantage in a variety of tasks involving attention control. The suggested interpretation is that the use of two languages requires a mechanism to control attention to the relevant language and ignore or inhibit interference from the competing language. This experience provides continual practice in attention control and results in its earlier development in children, improved functioning in adults, and slower decline in older age. 9 Therefore, bilingualism might contribute to cognitive reserve and protect older adults from decline in the context of dementia and AD. This hypothesis was examined. A Canadian study regarding Bilingualism and Dementia reports that speaking two languages can help delay the onset of Alzheimer’s symptoms by as much as 5 years18. This could be good news in India, where many people know multiple languages and can therefore choose to actively speak more than 1 language and acquire the claimed protection. Research on the correlation between bilingualism and Alzheimer’s has only started recently. Most studies mainly focus on the effects of neurological, social and environmental factors on the onset of AD. Their investigation indicated that some environmental factors may postpone the onset of symptoms and illnesses that produce dementia. For instance, sustained mental activity, and hence higher brain reserve, can protect against dementia and cognitive decline in elderly individuals19. A Canadian study regarding effects of bilingualism on the memory of elderly people - found that bilingualism enhanced attention and cognitive reserve in older adults. The eye movement study showed few differences between monolingual and bilingual subjects. Nonetheless, older bilingual subjects scored significantly higher during a key press response test. The behavioural study, therefore, indicated advantages in older bilingual subjects20. In a consecutive study, they investigated how dementia was influenced by bilingualism. They examined the effect of lifelong bilingualism on the onset of dementia in 10 old age. The study was conducted among 184 Canadian patients diagnosed with dementia and their caregivers. 51% of all patients were bilingual. To be considered as bilingual, patients had to have spent a majority of their lives using two languages. Results of this study showed that on average bilingualism delays the onset of dementia by an average of 4.1 years concluded that there is no difference between the results for men and those for women21. Even though a comparison of the level of education showed that bilinguals had often had less education, educated monolinguals showed few advantages over uneducated bilinguals. Apart from the level of education, the primary occupation of the patients was compared. Results indicated that bilinguals with the same occupational status as monolinguals developed the first symptoms of dementia at a later age. Some knowledge of another language is not sufficient to be considered as being bilingual. Furthermore, they mention that this study may be seen as subjective since most data relies on reports of the patient, family members or caretakers. They nevertheless conclude that the research has indicated that bilingualism can be considered as a possible factor to protect against dementia and AD and cognitive decline in elderly individuals. These reviews are, therefore, the motivation to conduct a structured teaching program among monolingual adults between the age group of 35-50 years at rural community in Tumkur, in order to improve their knowledge regarding this new area of study, as well as motivate them to learn a new language towards off Alzheimer’s and helps to keep the brain young. 11 6.2 REVIEW OF LITERATURE “Literature review is a critical summary of research on a topic of interest, often prepared to put a research problem in context or as the basis for an implementation project”. Polit and Hungler A secondary analysis was conducted about the ‘positive Effects of Bilingualism in the Adult Mind and Brain’, on September 23, 2011 a by Dr. Judith F. Kroll, Director of Center for Language Science Pennsylvania State University, and found the past 20 years of research shows that the cognitive development of bilingual children is advantaged relative to their monolingual counterparts, that bilingualism confers positive consequences, in the domain of executive function and attention control, and that life as a bilingual provides protection against the typical cognitive declines observed in old age.22 A secondary analysis was conducted in City University of New York Graduate Center by Loraine K. obler, Ph.D, distinguished professor program in Speech- LanguageHearing Sciences on August 19, 2010.He analysed more than 150 reviews since 1985 regarding bilingualism and Dementia/AD. The suggested interpretation is that the use of two languages requires a mechanism to control attention to the relevant language and ignore or inhibit interference from the competing language. These experiences provide continual practice in attention control and results in its earlier development in children, improved functioning in adults, and slower decline in older age. Therefore, bilingualism might 12 contribute to cognitive reserve and protect older adults from decline in the context of dementia and AD23. A study was conducted in Canada between 2007-2010 regarding lifelong bilingualism and Dementia/AD. Data were collected from 211 consecutive patients diagnosed with probable Alzheimer’s disease (AD). Patients’ age at onset of cognitive impairment was recorded, as was information on occupational history, education, and language history, including fluency in English and any other languages. Following this procedure, 102 patients were classified as bilingual and 109 as monolingual. They found that the bilingual patients had been diagnosed 4.3 years later and had reported the onset of symptoms 5.1 years later than the monolingual patients. The groups were equivalent on measures of cognitive and occupational level, there was no apparent effect of immigration status, and the monolingual patients had received more formal education. There were no gender differences. The data confirm results from an earlier study, and thus they concluded that lifelong bilingualism confers protection against the onset of AD. The effect does not appear to be attributable to such possible confounding factors as education, occupational status, or immigration.24 A study was conducted in Karnataka, India between 2008-2010 to qualify the cognitive-linguistic performance in persons with dementia as compared to healthy elderly. There were 80 participants: 20 persons with diagnosis of mild dementia (10 monolinguals and 10 bilinguals) and 60 healthy elderly (30 monolinguals and 30 bilinguals). A diagnosis 13 of probable dementia was made according to DSM IV criteria. Each patient attended a geriatric clinic at National Institute of Mental Health and Neurosciences (NIMHANS) where they underwent thorough medical screening in order to rule out any other treatable pathology that could explain their impairment. Healthy elderly participants were not suffering from any neurological or psychological illness likely to impair performance and were not complaining of memory or other cognitive difficulties. There were no significant differences in the distribution of males and females (p> 0.05). Also the participants in the dementia group exhibited similar cognitive decline despite having different types of dementia25. A comparison survey was conducted in Jammu district, North India, between 2007 and 2008, to ascertain the prevalence of dementia (AD) in the population aged 60 years and above, and to compare prevalence of dementia (AD) in the different populations of Jammu district. They conducted two stage cross-sectional epidemiological studies of 1,856 subjects aged 60 years and above, using cognitive and functional ability screening and clinical evaluation. The overall prevalence of dementia in the 60 years and over population was 1.83%, with a small gender difference. The prevalence of dementia in ethnic Dogra population of Jammu district, North India was lower (1.83%) in comparison to the migrant Kashmiri Pandit population residing in the same District, as well as the prevalence of dementia increased with advancing age. Individuals with age 85 and above showed the 14 highest prevalence with females recording slight increase. Significant prevalence of dementia was reported only afterage 75 years and above26. A pilot study was conducted in the Flemish Community of Belgium to investigating the effects of bilingualism on subjects diagnosed with dementia. The survey was aimed at both monolingual and multilingual subjects diagnosed with any form of dementia. In order to obtain a representative sample of both subject groups, approximately sixty rest homes or nursing homes in Belgium were contacted by telephone. They measured the significance of the correlation between monolingual and bilingual subjects, and the age of onset of dementia by means of an Independent Samples t-test. The study shows a considerable difference in age of onset between Belgian and Canadian subjects. Bialystok et al. (2007) indicated that their monolingual subjects developed the first symptoms of dementia at 71.4 years whereas in this study, monolinguals showed the first symptoms of dementia at 78.8 years. Canadian bilingual subjects developed the first symptoms of dementia at 75.5 years compared to 79.1 years for Belgian bilingual subjects. Thus, they assume that Canadians are more likely to develop the onset of dementia at an earlier age than Belgians27. A study was conducted St. Michael's Hospital in Canada, in order to find the correlation between Alzheimer’s and bilingualism. The researchers studied the CT scans of 40 patients whose cognitive skills – including attention, memory, planning and 15 organizational abilities - were found on testing to be similar. Half the patients were fluently bilingual while the other half spoke only one language. The scans of the bilingual patients showed twice as much atrophy in areas of the brain known to be affected by Alzheimer's. So they concluded that the bilingual people are constantly using their brain and keeping it active, which may contribute to overall brain health. That's why many physicians encourage older people to do crossword puzzles or Sudoku. Previous observational studies have found that bilingualism delays the onset of Alzheimer's symptoms by up to five years, but this was the first to find physical proof through CT scans28. A study was conducted by San Diego State University, York University, and Wellesley College between 2007 and 2008 regarding cognitive control in bilinguals, to know whether Bilinguals often outperform monolinguals on nonverbal tasks that require resolving conflict from competing alternatives. The regular need to select a target language is argued to enhance executive control. They investigated whether this enhancement stems from general effect of bilingualism or from a modality constraint that forces language selection. They compared the performance of 15 monolinguals, 15 bimodal bilinguals, and 15 unimodal bilinguals on a set of flanker tasks. There were no group differences in accuracy, but unimodal bilinguals were faster than the other groups; bimodal bilinguals did not differ from monolinguals. These results trace the bilingual advantage in cognitive control to the unimodal bilingual’s experience controlling two languages in the same modality.29 16 A door-to-door survey was conducted to investigate the prevalence, psychosocial correlates and risk factors of various dementing disorders in an urban population in Kerala, southern India on 2005. They selected sample from the city of Kochi (Cochin) by using cluster sampling, to identify residents aged ≥65 years . Of 1934 people screened with a vernacular adaptation of the Mini-Mental State Examination, all those scoring at or below the cut-off of 23 were evaluated further and those with confirmed cognitive and functional impairment were assigned diagnoses according to DSM-IV criteria. Identified cases were categorised by ICD-10 criteria. Ten per cent of those screened as negative were evaluated at each stage. The prevalence of dementia was 33.6 per 1000 (95% CI 27.3-40.7). Alzheimer's disease was the most common type (54%) followed by vascular dementia (39%), and 7% of cases were due to causes such as infection, tumour and trauma. According to this survey Dementia (AD) is an important health problem of the elderly population30. A study was conducted in the Memory Clinic at Bay crest in Toronto, Canada, between 2002 and 2005 to examine the effect of lifelong bilingualism on maintaining cognitive functioning and delaying the onset of symptoms of dementia in old age. The sample was selected from the records of 228 patients referred with cognitive complaints. In addition to a medical history, physical examination, and mental status evaluation, patients were usually assessed with CT, SPECT, and screening blood tests. The final sample consisted of 184 patients, of whom 91 were monolingual and 93 were bilingual. There were 66 patients in each language group diagnosed with probable AD, comprising 73% of monolinguals and 71% of the bilinguals diagnosed with dementias. The bilinguals showed 17 symptoms of dementia 4 years later than monolinguals, all other measures being equivalent. Additionally, rate of decline in Mini-Mental State Examination (MMSE) scores over the 4 years subsequent to the diagnosis was the same for a subset of patients in the two groups, suggesting a shift in onset age with no change in rate of progression31. An article reports the findings of a 3-year epidemiological survey for dementia in an urban community-resident population in Mumbai (Bombay), India, wherein the prevalence of all types of dementia was determined. From a potential pool of 30,000 subjects aged 40 years or more, 24,488 (male = 11,875; female = 12,613) persons completed self-report or interviewer-rated protocols based on the Sandoz Clinical Assessment Geriatric Scale, but 5,512 (18.37%) persons refused to participate. The prevalence rate for dementia in those aged 40 years and more was 0.43% and for persons aged 65 and above was 2.44%. Seventy-eight individuals had a CDR of [greater-than-or-equal] 1 yielding an overall prevalence rate of 0.32%, and a prevalence rate of 1.81% for those aged 65 years and older. The overall prevalence rate for Alzheimer's disease (AD) in the population was 0.25%, and 1.5% for those aged 65 years and above. The prevalence of AD and other dementias is less than that reported from developed countries but similar to results of other studies in India. Prevalence of the dementia syndrome increased with age. AD was the most common dementia and the prevalence was higher in women than in men32. 18 STATEMENT OF THE PROBLEM. “A Study To Assess The Effectiveness Of Structured Teaching Programme On Knowledge Regarding Protective Effect Of Bilingualism On Alzheimer’s Disease Among Monolingual Adults Between The Age Group Of 35-50 Years At Selected Rural Communities In Tumkur.” 6.3 OBJECTIVES OF THE STUDY: 1. To assess the pre-test level of knowledge regarding the protective effect of bilingualism on Alzheimer’s disease among monolingual adults between the age group of 35-50 years. 2. To assess the pre-test level of knowledge regarding the protective effect of bilingualism on Alzheimer’s disease among monolingual adults between the age group of 35-50 years. 3. To evaluate the effectiveness of structured teaching programme by comparing pre-test and post–test scores. 4. To determine the association between the post-test level of knowledge with selected socio-demographic variables among monolingual adults between the age group of 35-50 years. 19 6.4 RESEARCH HYPOTHESIS: H1: The mean post-test knowledge level of mono lingual adults age group between 35-50 years, regarding the protective effect of bilingualism on Alzheimer’s disease will be significantly higher than the mean pre-test knowledge level of mono lingual adults. H2: There will be significant association between the knowledge level and socio demographic variables. 6.5 OPERATIONAL DEFINITIONS: ASSESS: It refers to gathering information about knowledge level of mono lingual adults age group between 35-50 years, regarding the protective effect of bilingualism on Alzheimer’s disease. EFFECTIVENESS:It refers to the extent to which the structured teaching programme will be helpful in gaining knowledge regarding protective effect of bilingualism on Alzheimer’s.. STRUCTURED TEACHING PROGRAMME: It is a systematically developed programme with teaching aids designed to impart knowledge regarding protective effect of bilingualism on Alzheimer’s. BILINGUALISM: it refers to adults knowing more than one language to read and write. MONOLINGUALISM: it refers to adults knowing only one language to read and write. ALZHEIMERS: it is a progressive degenerative disease which attacks the tissues of the brain and results in impaired memory, thinking, behaviour and emotions. 20 6.6 ASSUMPTIONS 1. The adults may have low level of knowledge regarding protective effect of bilingualism on Alzheimer’s disease before doing structured teaching programme. 2. Structured teaching programme may improve their knowledge. 6.7 DELIMITATION • Study is limited to only 60 samples in each group. • Study is limited to monolingual adults’ age group between 35-50 years. • Study is limited to 6 weeks. 21 7. MATERIALS AND METHODS OF THE STUDY: 7.1 SOURCE OF DATA: The data will be collected from monolingual adults age group between 35-50 years at selected rural community in Tumkur.. 7.2 METHODS OF DATA COLLECTION: Data will be collected by using structured questionnaire after obtaining prior permission from the authority. 7.2.1 TYPE OF STUDY/RESEARCH APPROACH: Experimental approach will be chosen to conduct the study. 7.2.2 RESEARCH DESIGN: One group pre-test post-test pre-experimental design is chosen for conducting the study. 22 7.2.3 VARIABLES OF THE STUDY: 1. Dependent variable: Knowledge level regarding protective effect of bilingualism on Alzheimer’s disease among monolingual adults age group between 3550 years.. 2. Independent variable: Structured teaching programme. 3. Attributing variable: demographic variables such as age, sex, family, place of living urban/rural etc. 7.2.4. SETTINGS OF THE STUDY The study will be conducted at selected areas in Tumkur. 7.2.5 POPULATION The population will comprise at selected area in Tumkur. 7.2.6 SAMPLE AND SAMPLE SIZE: Sample size of the study is 60 monolingual adults between the age group of 3550 years. 23 7.2.7 SAMPLING TECHNIQUE: Simple Random sampling technique by using lottery method will be used to select the samples. 7.2.8 CRITERIA FOR SELECTION OF SAMPLE: Inclusion criteria: 1. Both males and females. 2. Monolingual adults aged between 35 and 50 years. Exclusion criteria: 1. Monolingual adults who are not willing to participate. 2. The individual who got other severe illness. 3. Monolingual adults who are not available/absent at the time of data collection. 7.2.9 FOLLOW UP The post-test will be conducted after one week of pre-test. 7.2.10 COMPARISON PARAMETER Yes, the pre-test and post-test level of knowledge will be compared within the group. 24 7.2.11 DURATION OF STUDY The study will be planned to conduct within 6-8 weeks of duration. 7.2.12 INSTRUMENT: Instruments consist of two sections: • Section A: Demographic profile of the monolingual adult between the age group of 35-50 years. • Section B: Questionnaire; It consist of questions to assess the knowledge regarding correlation of bilingualism and Alzheimer’s among monolingual adult between 35-50 years at selected rural area in Tumkur. 7.2.13 METHOD OF DATA ANALYSIS AND PRESENTATION The data collected through structured questionnaire will be carefully recorded and analysed through following techniques. Descriptive analysis 1. Frequency and percentage analysis will be used to describe the demographic characteristics of monolingual adult. 2. Descriptive analysis such as mean, range standard deviation and mean score per cent will be used to assess the knowledge regarding correlation of bilingualism and Alzheimer’s among monolingual adult between 35-50 years. 25 3. Inferential statistics • Paired t - Test will be carried out to assess the statistical significance and compare the pre • and post-test knowledge score . The Chi -Square analysis will be used to determine the association between knowledge and selected demographic variables. 7.3 DOES THE STUDY REQUIRE ANY INTERVENTIONS TO BE ON CONDUCT PATIENTS OR OTHER HUMAN OR ANIMALS? Yes, this study involves the intervention of structured teaching programme. 7.4 HAS ETHICAL CLEARANCE BEEN OBTAINED FROM YOUR INSTITUTION? Ethical clearance will be obtained from Institutional Ethical Committee (IEC) and the permission will be obtained from the P.H.C. for data collection. A pilot study will be conducted to assess the feasibility and main study will be conducted after getting the consent from the subject. 26 8. LIST OF REFERENCES REFERENCE 1. Saritha Bhalotra MD,PhD .A National study of wellbeing at Midlife .The new England journal of medicine 2004. 2. Ms Malhothra A K. Caring in Alzheimer’sDisease. The Nursing Journal Of India 1999; LXXXX (2):29-32. 3. Bialystok Ellen, Craik, Fergus I.M. et al. Neuropsychologia. 2007 February;45(2): 459464. 4. Bhatia, Tej K. &Ritchie, William C. Dementia- The Handbook of Bilingualism. Oxford:Blackwellpublishing.http://www.alzheimers.org.uk/site/scripts/ documents.php categoryID=200120.2006 5. Bialystok, E., Craik, F.I.M., & Ryan, J. Executive control in a modified anti-saccade task: Effects of aging and bilingualism. 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