Cell Signaling
Supplemental Instruction
Iowa State University
Leader:
Course:
Instructor:
Date:
Caleb I.
BIOL 212
Dr. Kukday
3/1/2017
1.) Vocabulary Review- Match the Terms & Definitions:
a. A broad term describing a
i.
Short Distance Signaling ___
sequence of proteins and
ii.
Long Distance Signaling ___
messaging molecules
iii. Ligand ______
b. A pathway where signals are
iv.
Signal Transduction Pathway
transduced via ion channels
____
c. Passing information from one
v.
Enzyme-Linked Receptor
cell to another cell in direct
contact or nearby
____
d. A pathway where signals are
vi.
G-Protein Coupled Receptor
transduced when an epinephrine
______
receptor binds to the protein
vii.
Ligand-Gated Receptor
e. A pathway where signals are
______
transduced through proteins in
the membrane that bind with
enzymes
f. Passing a message through the
blood stream or some other
pathway to cells not close to
each other.
g. The specific binding factor that
will bind to a (normally larger)
surface protein
2.) Can you connect the 4 steps in cell signaling to each of the examples provided? For
example, what part of the apoptosis pathway can be considered signal processing? ----List the 4 steps in cell-cell signaling. Identify each of the steps on the picture below:
i.
ii.
iii.
iv.
1060 Hixson-Lied Student Success Center  515-294-6624  [email protected]  http://www.si.iastate.edu
3.) Can you identify the types of receptors (cell surface and intracellular) that a cell uses to
receive signals from their environment? ----- List the 3 types of receptors we learned
about. What are the differences between these types of receptors?:
i.
ii.
iii.
4.) Can you describe the role of cAMP in signal transduction? Are there examples of other
molecules that perform a similar role?
1060 Hixson-Lied Student Success Center  515-294-6624  [email protected]  http://www.si.iastate.edu
5.)
Dr. Kukday’s “Can You?” Questions:
1.) Can you connect the 4 steps in cell signaling to each of the examples provided? For
example, what part of the apoptosis pathway can be considered signal processing?
2.) Can you identify the types of receptors (cell surface and intracellular) that a cell uses to
receive signals from their environment?
3.) Can you describe the role of cAMP in signal transduction? Are there examples of other
molecules that perform a similar role?
4.) Can you illustrate key steps in the signaling pathway for EGF and epinephrine? How is
the signal transmitted in both cases? What is the final response for each pathway? What
are the differences between the two pathways?
1060 Hixson-Lied Student Success Center  515-294-6624  [email protected]  http://www.si.iastate.edu