Prof. Massimo Castagnola – Publications and book chapters
1) M. Castagnola, B. Floris, G. Illuminati, G. Ortaggi
The electron donor properties of Ferrocene. The oxidation of Ferrocene by carboxylic acids.
J. Organomet. Chem. 60, (1973) 17-18.
2) G.B. Rossi, C. Ramoni, A. Dolei, M.L. Salvi, M. Castagnola.
Studio dell'espressione di antigeni emoglobinici e virali in cellule leucemiche indotte dal Virus
di Friend e trattate con dimetilsolfossido e/o interferone, mediante l'immunofluorescenza.
In "Problemi di oncologia virale: virus oncogeni e differenziamento cellulare" G.B. Rossi
Ed.; Tip. Cerroni -Roma; (1976) pag 57-92.
3) G.B. Marini Bettolo, C. Nigro, R. Garcia, M. Castagnola, A. De Gregori.
Research on the humic acids of Italian soils.
Agrochim. 21, (1977) 429-442.
4) M. Castagnola, R. Garcia de Las Heras, G.B. Marini Bettolo.
Effect of urea on electrophoretic pattern of soil humic acid.
J. Chromatogr. 147, (1978) 438-442.
5) M. Castagnola, C. Nigro, G.B. Marini Bettolo, A. Milana, R. Garcia de Las Heras.
Characterization of soil humic acid by combined polyacrylamide disc electrophoresis and chromatic
reactions.
J. Chromatogr. 177, (1979) 130-134.
6) S. Onofri, M. Castagnola, S. Rossi Espagnet.
L'impiego della microscopia elettronica a scansione in micologia.
Micol. Ital. 1, (1980) 29-32.
7) M. Castagnola, F. Villani
Stereospecific effect of S(+) and R(-) amphetamine on the release of dopamine and serotonine
from "nerve ending synaptosomes.
Rend. Acc. Naz. delle Scienze 98, (1979-1980) 153-160.
8) N. Mora de Gonzalez, M. Castagnola, D.Rossetti.
Humic acid characterization of colombian soil by disc electrophoresis and infrared spectroscopy
following gel filtration.
J. Chromatogr. 209, (1981) 421-431.
9) M. Castagnola, M.L. Salvi, D. Rossetti, P. Caradonna.
The non enzymatic glycosylation of proteins.
LAB, J. Res. Lab. Med. 8, (1981) 169-177.
10) P. Caradonna, M. Piccaro, M. Castagnola, E. Moneta.
L' emoglobina glicosilata nella preeclampsia.
Giornale Ital. Diabetol. 2, (1982) 117-123.
11) S. Onofri, M. Castagnola.
Scanning electron microscopy of some dematiaceous sympodially proliferating Hyphomycetes.
Mycotaxon 14, (1982) 125-139.
12) M. Castagnola, P. Caradonna, M.L. Salvi, D.V. Rossetti.
Investigation of the heterogeneity of hemoglobin by cation exchange chromatography on Bio-Rex
70.
J. Chromatogr. 272, (1983) 51-65.
13) M. Castagnola, P. Caradonna, M.L. Salvi, R. Pellicano, D. Rossetti.
The chromatographic separation of glycosylated haemoglobins: a comparison between macro- and
micromethods.
J. Clin. Chem. Clin. Biochem. 21, (1983) 223-226.
14) S. Onofri, M. Castagnola.
The genera Ardachandra and Rhinocladiella. Their synonymy.
Mycotaxon 18, (1983) 337-343.
15) M. Castagnola, P. Caradonna, L. Cassiano, C. Degen, F. Lorenzin, D. Rossetti, M.L. Salvi.
Analysis of the globins from fast human haemoglobins by isoelectrofucusing on polyacrylamide gel
rods.
J. Chromatogr. 307, (1984) 91-102.
16) R. Proietti, M.A. Pennisi, C. Barilaro, E. Gualtieri, M. Castagnola, S. Lippa, P. De Sole.
Effect of neurotrophil chemiluminescence of middle molecular weight substances present in
peritoneal dialysis fluid of patients with acute renal failure.
Acta Med. Rom. 22, (1984) 204-210.
17) L. Polonelli, D. Orsini, M. Castagnola, G. Morace.
Serological identification of aflatoxins potentially producing Aspergillus species.
Igiene Mod. 81, (1984) 1126-1136.
18) G. Morace, D. Orsini, M. Castagnola, L. Polonelli.
Exoantigen studies of Phanerochaete chrysosporium and Sporotricum pruinosum coltures.
Igiene Mod. 81, (1984) 314-321.
19) R. Colli, G. Cina, A. Ferrante, N. Maggiano, M. Castagnola, V. Di Giovanni.
Sostituzioni protesiche della vena cava inferiore: uso di un nuovo materiale (mitrathane). Risultati a
breve termine.
Chirur. Patol. Sperim. 32, (1984) 111-127.
20) M. Castagnola, P. Caradonna, R. De Cristofaro, P.P. Sanna, D.V. Rossetti, M.L. Salvi.
Evaluation of the thiobarbituric acid test (TBA test) properties for the determination of glycosylated
hemoglobins by comparison with chromatography and isoelectrofocusing.
J. Lab. Med. 12, (1985),183-189.
21) A. Bianconi, A. Congiu-Castellano, M. Dell'Ariccia, A. Giovannelli, E. Burattini, M.
Castagnola, P.J. Durham.
Changes in Fe site structure from fetal to adult hemoglobin probed by XANES.
Biochim. Biophys. Acta 831, (1985) 120-124.
2
22) L. Polonelli, M. Castagnola, D.V. Rossetti, G. Morace.
Use of killer toxins for computer aided differentiation of Candida albicans strains.
Mycopatol. 91, (1985) 175-179.
23) M. Castagnola, P. Caradonna, A. Bertollini, L. Cassiano, D.V. Rossetti, M.L. Salvi.
Determination of the non-enzymatic glycation of hemoglobin by isoelectrofocusing of its globin
chains.
Clin. Biochem. 18, (1985) 327-331.
24) M. Castagnola.
Glycosylated haemoglobin (Letter to Editor).
J. Clin. Pathol. 38, (1985) 1082-1083.
25) M. Grilli Caiola, M. Castagnola, G. Chichiriccò.
Ultrastructural study of Saffron pollen.
Giorn. Bot. Ital. 119, (1985) 61-66.
26) G. Morace, M. Castagnola, D.V. Rossetti, L. Polonelli.
Isolamento di tossine killer e loro utilizzazione per la differenziazione di ceppi di Candida Albicans
mediante un sistema computerizzato.
Igiene Mod. 83, (1985) 415-417.
27) G. Arcovito, A. Piermattei, C. Bacci, G. Pittela, M. Castagnola.
Dosimetria in fantoccio rigido di sorgenti per brachiterapia, con particolare riferimento allo I125.
Radiol. Med. 71, (1985) 426-432.
28) L. Polonelli, M. Castagnola, C. D'Urso, G. Morace.
Serological approaches for identification of Aspergillus and Penicillium species.
In "Advances in Penicillium and Aspergillus Systematics."; R.A. Samson and J.I. Pitt Eds.;
NATO ASI series. Vol 102; Plenum Press, New York-London; (1985) ; pag. 267-280.
29) L. Polonelli, M. Castagnola, G. Morace.
Identification and serotyping of Microsporum canis isolates by monoclonal antibodies.
J. Clin. Microbiol. 23, (1986) 609-615.
30) M. Castagnola, R. Landolfi, D.V. Rossetti, F. De Angelis, S. Ceccarelli.
Determination of abnormal hemoglobin by the combined use of reversed-phase high performance
liquid chromatography and fast atom bombardment mass spectrometry.
Anal. Lett. 19, (1986) 1793-1807.
31) S. Onofri, . Maggi, A.M. Persiani, M. Castagnola.
Scanning electron microscopy of Heterocephalum (Hyphomycetes).
Trans. Br. Mycol. Soc. 87, (1986) 551-556.
32) R. Landolfi, R. De Cristofaro, M. Castagnola, L. Cudillo, D. Scribano, G. Leone.
Spontaneous deep haematomas in two patients with myelofibrosis: evidence of platelet membrane
glycoprotein modification.
Haematologica 72, (1987) 45-48.
3
33) L. Polonelli, G. Morace, R. Rosa, M. Castagnola, J.C.Frisvald.
Antigenic characterization of Penicillium camemberti and related common cheese contaminants.
Appl. and Envir. Microbiol. 53, (1987) 872-878.
34) A. Congiu Castellano, A. Bianconi, M. Dell'Ariccia, S. Della Longa, A. Giovannelli, E.
Burattini, M. Castagnola.
Oxygen bonding in human haemoglobin and its isolated subunits: a XANES study.
Biochem. Biophys. Res. Comm. 147, (1987) 31-38.
35) R. Landolfi, R. De Cristofaro, M. Castagnola, E. De Candia, G. D'Onofrio, G. Leone, B.
Bizzi.
Increased platelet-fibrinogen affinity in patients with myeloproliferative disorders.
Blood 71, (1988) 978-982.
36) L. Polonelli, G. Dettori, G. Morace, R. Rosa, M. Castagnola, M.A.A. Schipper.
Antigenic studies on Rhizopus microsporum, Rhizopus rhizopodiformis progeny and intermediate
(Rh. chinensis).
Antonie van Leeuwehoek J. Microbiol. Serol. 54, (1988) 5-18.
37) M. Coletta, G. Amiconi, A. Bellelli, A. Bertollini, J. Carsky, M. Castagnola, S. Condò, M.
Brunori.
Alteration of T-state binding properties of naturally glycated haemoglobin HbA1c.
J. Mol. Biol. 203, (1988) 233-239.
38) R. De Cristofaro, R. Landolfi, B. Bizzi, M. Castagnola.
Human platelet glycocalicin purification by phenyl-boronate affinity chromatography coupled to
anion exchange high performance liquid chromatography.
J. Chromatogr. 426, (1988) 376-380.
39) M. Castagnola, M. Dobosz, R. Landolfi, V.L. Pascali, F. De Angelis, L. Vettore, G. Perona.
Determination of neutral haemoglobin variants by immobilized pH gradient, reversed phase high
performance liquid chromatography and fast atom bombardment mass spectrometry: the case of a
Hb Torino 43 (CE1) PheVal.
Biol. Chem. Hoppe-Seyler 369, (1988) 241-246.
40) M. Castagnola, L. Cassiano, R. De Cristofaro, R. Landolfi, D.V. Rossetti, G.B. Marini Bettolo.
High performance liquid chromatography in protein sequence determination.
J. Chromatogr. 440, (1988) 231-251.
41) R. De Cristofaro, R. Landolfi, E. De Candia, M. Castagnola, E. Di Cera, J. Wyman.
Allosteric equilibria in the binding reaction of fibrinogen to platelets.
Proc. Nat. Acad. Sci. USA 85, (1988) 8473-76.
42) P. Ascenzi, A. Desideri, G. Amiconi, A. Bertollini, M. Castagnola, M. Coletta, M. Brunori.
Effect of inositol hexakisphosphate on the spectroscopic properties of the nitric oxide derivative of
ferrous naturally glycated human hemoglobin HbA1c.
J. Inorganic. Biochem. 34, (1988) 19-24.
4
43) M. Castagnola, L. Cassiano, R. De Cristofaro, S. Luciani, D.V. Rossetti, R. Landolfi.
Exopeptidase high performance liquid chromatography (HPLC) mapping and its application to
peptide sequence strategies.
Acta Med. Romana 26, (1988) 372-384.
44) M. Grilli-Caiola, C. Forni, M. Castagnola.
Bacteria in the Azolla-Anabaena association.
Symbiosis 5, (1988) 185-198.
45) A. Bianconi, M. Castagnola, A. Congiu Castellano.
XANES spectroscopy of isolated gamma chain of the human foetal hemoglobin.
Invated paper at "Proc. Intern. Congress of Biophysics and Synchrotron Radiation" Chester, U.K.,
(1988), pp 64-71.
46) E. Di Cera, M.L. Doyle, M.S. Morgan, R. De Cristofaro, R. Landolfi, B. Bizzi, M. Castagnola,
S. J. Gill.
Carbon monoxyde and oxygen binding to human hemoglobin F0.
Biochemistry 28, (1989) 2631-2638.
47) A. Congiu-Castellano, M. Castagnola, E. Burattini, M. Dell'Ariccia, S. Della Longa, P.J.
Durham, A. Bianconi.
Heterogeneity of the isolated subunits of the foetal and adult human hemoglobin in solution,
detected by XANES spectroscopy.
Biochim. Biophys. Acta 996, (1989) 240-246.
48) M.L. Doyle, S.J. Gill, R. De Cristofaro, M. Castagnola, E. Di Cera.
Temperature and pH dependence of the oxygen-binding reaction of human fetal hemoglobin.
Biochem. J. 260, (1989) 617-619.
49) R. De Cristofaro, R. Landolfi, E. Di Cera, M. Castagnola, E. De Candia, B. Bizzi.
Inhibition of fibrinogen binding to human platelets by blockage of Na+/H+ exchange.
Biochem. Biophys. Res. Comm. 161, (1989) 1228-1232.
50) M. Castagnola, L. Cassiano, R. De Cristofaro, S. Luciani, D.V. Rossetti, R. Landolfi.
Purification of the isolated -chain of adult human haemoglobin from its post-translational
modification.
J. Chromatogr. 494, (1989) 310-317.
51) L. Polonelli. F. Fanti, S. Conti, L. Campani, M. Gerloni, M. Castagnola, G. Morace and G.
Chezzi.
Detection by immunofluorescent anti-idiotypic antibodies of yeast killer toxin cell wall receptors of
Candida albicans.
J. Immunol. Methods. 132, (1990) 205-209.
52) R. Ippoliti, D. Currell, E. Lendaro, A. Bellelli, M. Castagnola, M. Bolognesi and M.
Brunori.
Effect of aromatic isothiocyanates on the functional properties of human hemoglobin. Role of the
stereochemistry of the charge group.
Biophys. Chem. 37, (1990) 293-302.
5
53) M. Castagnola.
L'uso della cromatografia liquida ad elevata risoluzione per la determinazione di varianti
emoglobiniche.
Clin. Lab. 14(2), (1990) 85-94.
54) M. Castagnola, L. Cassiano, D.V. Rossetti, L. Marucci, A. Ferro, C. Scarano, M. Monaco,
A.M. Celozzi.
Hb K-Ibadan [46(CD5)Gly Glu] in an Italian family.
Hemoglobin 14(6), (1990) 647-651.
55) R. De Cristofaro, M. Castagnola.
Kinetic aspects of release of fibrinopeptides AP and AY by human -thrombin.
Haemostasis 21, (1991) 85-90.
56) E. Cernia, A.D. Magrì, G. Ortaggi, M. Castagnola, R. Rabino, F. Bartoli.
Lypolytic enzymes separation and purification through functionalized synthetic polymers.
in "Lipases: structure, mechanism and genetic engineering", L. Alberghina, R.D. Schmid, R.
Verger Eds.; GBF monograph Vol. 16; VCH; (1991), pp.369-372.
57) M. Castagnola, L. Cassiano, R. Rabino, D.V. Rossetti, F. Andreasi Bassi.
Peptide mapping through the coupling of capillary electrophoresis and high-performance liquid
chromatography: map prediction of the tryptic digest of myoglobin.
J. Chromatogr. 572, (1991) 51-58.
58) L. Polonelli, S. Conti, M. Gerloni, W. Magliani, M. Castagnola, G. Morace, C. Ghezzi.
'Antibiobodies': antibiotic-like anti-idiotypic antibodies.
J. Med. Veter. Mycology 29, (1991) 235-242.
59) M. Castagnola, L. Cassiano, T. Petitti, R. Rabino, D.V.Rossetti , E. Valente.
Attualita' e prospettive della elettroforesi capillare.
Clin. Lab. 16(1), (1992) 1-10.
60) M. Brunori, G. Antonini, M. Castagnola, A. Bellelli.
Cooperative cyanide dissociation from ferrous hemoglobin.
J. Biol. Chem. 267, (1992) 2258-2263.
61) S.G. Condò, M. Corda, M.T. Sanna, M.G. Pellegrini, M.P. Ruiz, M. Castagnola, B. Giardina.
Molecular basis of the low temperature sensitivity in pig hemoglobins.
Eur. J. Biochem. 209, (1992) 773-776.
62) S. Aime, W. Dastrù, M. Fasano, A. Arnelli, M. Castagnola, B.Giardina, P. Ascenzi.
Quantitative determination of methemoglobin by measuring the solvent water proton-nuclear
magnetic resonance relaxation rate.
Clin. Chem. 38, (1992) 2401-2404.
63) M. Grilli Caiola, C. Forni, M. Castagnola.
Anabaena azollae Akinetes in the Sporocarps of Azolla filiculoides Lam.
Symbiosis 14, (1992) 247-264.
6
64) A. Congiu Castellano, M. Barteri, A. Bianconi, E. Borghi, L. Cassiano, M. Castagnola, S.
Dalla Longa, A. La Monaca.
X-ray small angle scattering of human transferrin protein aggregates: a fractal study.
Biophys. J. 64, (1993) 520-524.
65) B. Giardina, R. Scatena, M.E. Clementi, L. Cerroni, M. Nuutinen, O. Brix, S.N. Sletten, M.
Castagnola, S.G. Condò.
The physiological relevance of the overall H of oxygen binding to foetal human hemoglobin.
J. Mol. Biol. 229, (1993) 512-516.
66) M. Castagnola, D.V. Rossetti, L. Cassiano, R. Rabino, G. Nocca, B. Giardina.
Optimization of phenylthiohydantoinamino acids separation by micellar electrokinetic capillary
chromatography.
J. Chromatogr. 638, (1993) 327-334.
67) M. Castagnola, D. Di Pierro, R. Scatena, B. Tavazzi, G. Nocca, D.V. Rossetti, B. Giardina.
Separation of reduced and oxidized glutathione by micellar electrokinetic capillary
chromatography.
Biomed. Chromatogr. 7, (1993) 220-226.
68) M. Castagnola, L. Cassiano, I. Messana, R. Rabino, D.V. Rossetti.
Le potenzialità dell'elettroforesi capillare e delle tecniche derivate.
Scritti in ricordo ed in onore di Antonio Sanna Vol. II.
L'Igiene Mod. 100, (1993) 559-589
69) A. Congiu Castellano, M. Barteri, M. Castagnola, A. Bianconi, E. Borghi.
Structure-function relationship in the serotransferrin: the role of the pH on the conformational
change and the metal ion release.
Biochem. Biophys. Res. Comm. 198, (1994) 646-652.
70) M. Castagnola, L. Cassiano, I. Messana, G. Nocca, R. Rabino, D.V. Rossetti, B. Giardina.
Capillary zone electrophoresis of peptides: prediction of the electrophoretic mobility and resolution.
J. Chromatogr. B 656, (1994) 87-97.
71) M.T. Sanna, B. Giardina, R. Scatena, M. Pellegrini, A. Olianas, L. Manca, B. Masala, M.
Castagnola, M. Corda.
Functional alterations in adult and fetal hemoglobin Sassari asp-126 (H9)His. The role of 12
contact.
J. Biol. Chem. 269, (1994) 18338-18342.
72) M.E. Clementi, S.G. Condò, M. Castagnola, B. Giardina.
Hemoglobin function under extreme life conditions. (Review)
Eur. J. Biochem. 223, (1994) 309-317.
73) M. Piastra, A. Stabile, G. Fioravanti, M. Castagnola, G. Pani, F. Ria.
Cord blood mononuclear cell responsiveness to beta-lactoglobulin: T-cell activity in ‘atopy-prone’
and ‘non-atopy-prone’ newborns.
Int. Arch. Allergy Immunol. 104, (1994) 358-365.
7
74) E. Cernia, G. Ortaggi, S. Soro, M. Castagnola.
Esters of cross-linked polyvinyl alcohol with fatty acids: new stationary phases for the separation of
lipolytic enzymes.
Tetrahedron Lett. 35, (1994) 9051-9054.
75) B. Giardina, I. Messana, M. Castagnola.
Oxygen transport under extreme life conditions.
In “Structural and dynamical models of biomedical interest”, A. Colosimo Ed., (1994) pp. 56-67.
76) R. Scatena, G. Nocca, I. Messana, P. De Sole, S. Baroni, C. Zuppi, M. Castagnola, B.
Giardina.
Effect of gemfibrozil on the oxygen transport properties of erythrocytes.
Br. J. Clin. Pharmacol. 39, (1995) 25-30.
77) M. Castagnola, L. Cassiano, A. Lupi, I. Messana, M. Patamia, R. Rabino, D.V. Rossetti, B.
Giardina.
Ion-exchange electrokinetic capillary chromatography with starburst (pamam) dendrimers: a route
towards high-performance electrokinetic capillary chromatography.
J. Chromatogr. A 694, (1995) 463-469.
78) M. Coletta, P. Ascenzi, M. Castagnola, B. Giardina.
Functional and spectroscopic evidences for a conformational transition in ferrous liganded human
hemoglobin.
J. Mol. Biol. 249, (1995) 800-803.
79) B. Giardina, I. Messana, R. Scatena, M. Castagnola.
The multiple function of hemoglobin.
Critical Reviews Biochem. and Mol. Biol. 30, (1995) 165-196.
80) M. Castagnola, I. Messana, L. Cassiano, R. Rabino, D.V. Rossetti, B. Giardina.
The use of capillary electrophoresis for the determination of hemoglobin variants.
Electrophoresis 16, (1995) 1492-1498.
81) B. Giardina, M. E. Clementi, I. Messana, M. Castagnola.
Adattamenti fisiologici nelle emoglobine.
in “Evoluzione biologica e i grandi problemi della biologia: Molecole ed evoluzione.” M. Brunori
Ed. (1996), Acc. Naz. Lincei Ed. pp 69-85.
82) M. Castagnola, L. Cassiano, I. Messana, M. Paci, D.V. Rossetti, B. Giardina.
Effect of 2,2,2-trifluoroethanol on capillary zone electrophoretic peptide separations.
J. Chromatogr. A , 735 (1996) 271-281.
83) M.E. Clementi, R. Scatena, A. Mordente, S.G. Condò, M. Castagnola, B. Giardina.
Oxygen transport by fetal bovine hemoglobin.
J. Mol. Biol., 255 (1996) 229-234.
84) M. Castagnola, I. Messana, D.V. Rossetti.
Capillary zone electrophoresis for the analysis of peptides.
In “Capillary electrophoresis in analytical biotechnology” P.G. Righetti Ed.; Chapter 8. pp. 239276. (1996). CRC Series in Anal. Biotechnology. CRC Press, Boca Raton, New York, London,
Tokio.
8
85) I. Messana, M. Orlando, L. Cassiano, L. Pennacchietti,, C. Zuppi, M. Castagnola, B. Giardina.
Human erythrocyte metabolism is modulated by the O2-linked transition of hemoglobin.
FEBS Lett., 390 (1996) 25-28.
86) M. Castagnola, D.V. Rossetti, L. Cassiano, F. Misiti, L. Pennacchietti, B. Giardina, I. Messana.
Determination of peptide dissociation constants and Stokes radius at different protonation stages by
capillary electrophoresis.
Electrophoresis, 17 (1996) 1925-1930.
87) I. Messana, D.V. Rossetti, L. Cassiano, F. Misiti, B. Giardina, M. Castagnola.
Peptide analysis by capillary (zone) electrophoresis.
J. Chromatogr. B, 699 (1997) 149-171.
88) M. Castagnola, D.V. Rossetti, F. Misiti, L. Cassiano, B. Giardina, I. Messana.
Modification of capillary electrophoresis selectivity in hydro-organic solutions. Dissociation
constants and Stokes radius measurements of peptides in water-2,2,2-trifluoroethanol mixtures.
J. Chromatogr. A, 792 (1997) 57-65.
89) M. Castagnola, D.V. Rossetti, F. Misiti, L. Cassiano, B. Giardina, I. Messana.
Analytical methods for peptide drugs applicable to process control. (Review)
Process Control and Quality, 10 (1997) 181-203.
90) I. Messana, M. Castagnola, M. Orlando, L. Pennacchietti, B. Giardina
Esperimenti NMR di carbonio-13 sul metabolimo eritrocitario.
In: Spettroscopia di risonanza magnetica nucleare in biomedicina. ISSN 1123-3117. Rapporti
ISITAN 97/40. A.M. Luciani e A.Rosi Ed.– 53-64 (1997).
91) M.C. De Rosa, M.T. Sanna, I. Messana, M. Castagnola, A. Galtieri, E. Tellone, R. Scatena, B.
Botta, M. Botta, B. Giardina.
Glycated human hemoglobin (HbA1c): functional characteristics and molecular modeling studies.
Biophys. Chem., 72 (1998) 323-335.
92) I. Messana, M. Angeletti, M. Castagnola, G. De Sanctis, E. Di Stasio, B. Giardina, S.
Pucciarelli, M. Coletta.
Thermodinamics of inositol hexakis-phosphate interaction with human oxyhemoglobin.
J. Biol. Chem., 273 (1998) 15329-15334.
93) M. Castagnola
Sensitive to the yoctomole level.
Trends Biochem. Sci. , 23 (272) (1998) 283.
Reply.
Trends Biochem. Sci. , 24 (280) (1999) 129.
94) M.T. Sanna, B. Giardina, M. Pellegrini, A. Olianas, I. Messana, M. Castagnola, M. Corda.
Circe’s hemoglobin, human-pig hybrids: functional characterization and structural consideration.
Biochem. J., 335 (1998) 211-213.
9
95) M. Castagnola, D.V. Rossetti, M. Corda, M. Pellegrini, F. Misiti, A. Olianas, B. Giardina, I.
Messana.
The pH dependence of predictive models relating electrophoretic mobility to peptide chemicophysical properties in capillary zone electrophoresis.
Electrophoresis, 19 (1998) 2273-2277.
96) M. Castagnola, D.V. Rossetti, M. Corda, M. Pellegrini, F. Misiti, A. Olianas, B. Giardina, I.
Messana.
Predictive model for capillary electrophoretic peptide mobility in 2,2,2-trifluoroethanol-water
solution.
Electrophoresis, 19 (1998) 1728-1732.
97) L. Battinelli, M. Castagnola, E. Cernia, M. Delbò, F. Padula, A. Pala, S. Soro.
A three-steps chromatographic procedure and electrophoretic characterization of an active isoform
of Candida rugosa lipases.
IJBC, 4 (1998) 125-137.
98) B. Giardina, I. Messana, M. Castagnola, M. Coletta, G. Amiconi, P. Ascenzi
Emoglobine.
in “Enciclopedia Medica Italiana”, USES Ed. Firenze, Agg. II°; Tomo I°, pg 1833-1839, 1998
99) I.Messana, F. Misiti, S. el Sherbini, B. Giardina, M. Castagnola.
Quantitative determination of the main glucose metabolic fluxes in human erythrocytes by 13C- and
1
H-MR spectroscopy.
J. Biochem. Biophys. Methods, 39 (1999) 63-84.
100) M. Pellegrini, B. Giardina, M. Castagnola, A. Olianas, M.T. Sanna, A Fais, I. Messana, M.
Corda.
Low-temperature sensitivity and enhanced Bohr effect in red deer (Cervus elaphus) haemoglobin: a
molecular adaptative strategy to life at high altitude and low temperature.
Eur. J. Biochem., 260 (1999) 667-671.
101) M. Castagnola
20 anni di attività con G.B. Marini Bettolo all’Università Cattolica: gli studi sulla purificazione e
caratterizzazione di macromolecole biologiche.
In “G.B. Marini Bettolo (1915-1996). La figura e l’opera”; Accademia Nazionale delle Scienze
(detta dei XL) Ed., Scritti e Documenti XXIII, pp 371-373, 1999.
102) M.T.W. Hearn, H.H. Keah, R.I. Boysen, I. Messana, F. Misiti, D.V. Rossetti, B. Giardina, M.
Castagnola.
Determination of biophysical parameters of polypeptide retro-inverso isomers and their analogues
by capillary electrophoresis.
Anal. Chem., 72 (2000) 1964-1972
103) M. Corda, M.C. De Rosa, M. Pellegrini, M.T. Sanna, A. Olianas, A. Fais, L. Manca, B.
Masala, B. Zappacosta, S. Ficarra, M. Castagnola, B. Giardina.
Adult and fetal haemoglobin J-Sardegna [50 (CE8) HisAsp]: functional and molecular
modelling studies.
Biochem. J., 346 (2000) 193-199.
10
104) I. Messana, L. Ferroni, F. Misiti, G. Girelli, S. Pupella, M. Castagnola, B. Zappacosta, B.
Giardina
Blood bank conditions and erythrocytes: the progressive loss of metabolic modulation
Transfusion, 40 (2000) 353-360.
105) I. Messana, D.V. Rossetti, F. Misiti, F. Vincenzoni, E. Tellone, B. Giardina, M. Castagnola.
Determination of S-nitrosoglutathione in erythrocytes by capillary zone electrophoresis
Electrophoresis, 21 (2000) 1606-1610.
106) M. Castagnola.
Recent applications of capillary electrophoresis for the analysis of biological molecules.
Acta Medica Romana, 38 (2000) 491-516.
107) R. Medda, A. Padiglia, I. Messana, G. Floris, M. Castagnola.
Separation of diadenosine polyphosphates by capillary electrophoresis.
Electrophoresis, 21 (2000) 2412-2416.
108) R. Medda, A. Padiglia, A. Lorrai, B. Murgia, A. Finazzi Agrò, M. Castagnola, G. Floris.
Purification and properties of a nucleotide pyrophosphatase from lentil seedlings.
J. Protein Chem., 19 (2000) 209-214.
109) M. Castagnola, D. Congiu ,G. Denotti, A. Di Nunzio, M.B. Fadda, S. Melis, I Messana, F.
Misiti, R Murtas, A. Olianas, V. Piras, A. Pittau , G. Puddu.
Determination of the human salivary peptides histatins 1, 3, 5 and statherin by high-performance
liquid chromatography and by diode-array detection.
J Chromatogr B, 751 (2001) 153-160.
110) F. Misiti, M. Castagnola, C. Zuppi, B. Giardina, I. Messana
Role of ergothioneine on S-nitrosoglutathion catabolism.
Biochem. J., 356 (2001) 799-804.
111) I. Messana, F. Andreasi Bassi D.V. Rossetti, F. Misiti, F. Vincenzoni, C. Zuppi, B. Giardina,
M. Castagnola.
Capillary electrophoresis detection of a weak ion-paired interaction between Hepes and NAD+
which is sensible to the electric field strength; a secondary Wien effect at low fields.
J. Separ. Sci., 24 (2001) 717-722.
112) M. Castagnola, T. Cabras, G. Denotti, M.B. Fadda, G. Gambarini, A. Lupi, I. Manca, G.
Onnis, V. Piras, V. Soro, S. Tambaro, I. Messana.
Circadian rhythms of histatin 1, histatin 3, histatin 5, statherin and uric acid in whole human saliva
secretion.
Biological Rhythm Research, 33 (2002) 213-222.
113) M. Castagnola, C. Zuppi, D.V. Rossetti, F. Vincenzoni, A. Lupi, A. Vitali, E. Meucci, I.
Messana.
Characterization of dendrimer properties by capillary electrophoresis and their use as pseustationary
phases.
Electrophoresis, 23 (2002) 1769-1778.
11
114) F. Misiti, E. Meucci, C. Zuppi, F. Vincenzoni, B. Giardina, M. Castagnola, I. Messana.
O2-dependent stimulation of the pentose phosphate pathway by S-nitrosocysteine in human
erythrocytes.
Biochem. Biophys. Res. Comm., 294 (2002) 829-834.
115) A. Galtieri, E. Tellone, L. Romano, F. Misiti, E. Bellocco, S. Ficarra, A. Russo, D. Di Rosa,
M. Castagnola, B. Giardina, I. Messana.
Band-3 protein function in human erythrocytes: effect of oxygenation-deoxygenation.
Biochim. Biophys. Acta, (Biomembranes) 1564 (2002) 214-218.
116) M. Castagnola, D.V. Rossetti, R. Inzitari, A. Vitali, A. Lupi, C. Zuppi, T. Cabras, M.B.
Fadda, R. Petruzzelli, B. Giardina, I. Messana.
Affinity capillary electrophoresis study of the linkage existing between proton and zinc ion binding
to bacitracin A1.
Electrophoresis, 24 (2003) 801-807.
117) A. Lupi, I. Messana, G. Denotti, M.E. Schininà, G. Gambarini, M.B. Fadda, A. Vitali, T.
Cabras, V. Piras, M. Patamia, M. Cordaro, B. Giardina, M. Castagnola.
Identification of the human salivary cystatin complex by the coupling of high-performance liquid
chromatography and ion-trap mass spectrometry.
Proteomics, 3 (2003) 461-467.
118) M. Castagnola, D.V. Rossetti, R. Inzitari, A. Vitali, A. Lupi, C. Zuppi, T. Cabras, M.B.
Fadda, I. Podda, R. Petruzzelli, B. Giardina, I. Messana.
Capillary electrophoretic study of the binding of Zn(II) ion to bacitracin A1 in water-2,2,2trifluoroethanol.
Electrophoresis, 24 (2003) 1612-1619.
119) C. Zuppi, D.V. Rossetti, A. Vitali, F. Vincenzoni, B. Giardina, M. Castagnola, I. Messana.
Determination of urinary hippuric acid by micellar electrokinetic chromatography.
J. Chromatogr. B, 793 (2003) 223-228.
120) M. Pellegrini, B. Giardina, C. Verde, V. Carratore, A. Olianas, L. Sollai, M.T. Sanna, M.
Castagnola, G. Di Prisco.
Structural-functional characterisation of the cathodic haemoglobin of the conger eel, Conger
conger. Molecular modelling study of an additional phosphate-binding site.
Biochemical J., 372 (2003) 679-686.
121) G. Gambarini, M. Andreasi-Bassi, G. Bolognini, L. Testarelli, G. Nocca, L. Ceccarelli, R.
Scatena, A. Lupi, M. Castagnola.
Cytotoxicity of a new endodontic filling material.
Aust. Endod. J., 29 (2003) 17-19.
122) R. Scatena, P. Bottoni, F. Vincenzoni, I. Messana, G.E. Martorana, G. Nocca, P. De Sole, N.
Maggiano, M. Castagnola, B. Giardina.
Bezafibrate induces a mitochondrial derangement in human cell lines: a PPAR-independent
mechanism for a peroxisome proliferator.
Chem. Res. Toxicol., 16 (2003) 1440-1447.
12
123) M. Castagnola, T. Cabras, R. Inzitari, C. Zuppi, D.V. Rossetti, R. Petruzzelli, A. Vitali, F.
Loy, G. Conti, M.B. Fadda
Determination of the Post-Translational Modifications of Salivary Acidic Proline-Rich Proteins.
Eur. J. Morph., 41 (2003) 93-98.
124) I. Messana, F. Loffredo, R. Inzitari, T. Cabras, B. Giardina, G. Onnis, M. Piludu and M.
Castagnola
The Coupling of RP-HPLC and ESI-MS in the Study of Small Peptides and Proteins Secreted In
Vitro by Human Salivary Glands that are Soluble in Acidic Solution.
Eur. J. Morph., 41 (2003) 103-106.
125) M. Castagnola, D.V. Rossetti, R. Inzitari, A. Lupi, C. Zuppi, T. Cabras, M.B. Fadda, G.
Onnis, R. Petruzzelli, B. Giardina, I. Messana.
Different binding thermodynamics of Ni+2, Cu+2 and Zn+2 to bacitracin A1 determined by capillary
electrophoresis.
Electrophoresis, 25 (2004) 846-852.
126) I. Messana, T. Cabras, R. Inzitari, A. Lupi, C. Zuppi, C. Olmi, M.B. Fadda, M. Cordaro, B.
Giardina, M. Castagnola.
Characterization of the human salivary basic proline-rich protein complex by a proteomic approach.
J. Proteome Res. 3 (2004) 792-800.
127) M. Castagnola, S. Lippa, C. Zuppi, I. Messana
Chromatography of amino acids and peptides
in Chromatography, 6th edition: “Fundamentals and application of chromatography and differential
migration methods. Part B: applications.” Journal of Chromatography Library, Vol. 69B Erich
Heftman (Editor), Elsevier (2004), Chapter 14, pag. 587-631.
128) M.C. De Rosa, M. Castagnola, C. Bertonati, A. Galtieri, B. Giardina
From the Artic to fetal life: physiological importance and structural basis of an “additional” chloride
binding site in haemoglobin.
Biochemical J., 380 (2004) 889-896.
129) M. Castagnola, R. Inzitari, D.V. Rossetti, C. Olmi, T. Cabras, V. Piras, P. Nicolussi, M.T.
Sanna, M. Pellegrini, B. Giardina, I. Messana.
A cascade of 24 histatins (histatin 3 fragments) in human saliva: suggestions for a pre-secretory
sequential cleavage pathway.
J. Biol. Chem., 279 (2004) 41436-41443
130) R. Scatena, I. Messana, G. E. Martorana, M.L. Gozzo, S. Lippa, A. Maccaglia, P. Bottoni, F.
Vincenzoni, G. Nocca, M. Castagnola, B. Giardina.
Mitochondrial damage and metabolic compensatory mechanisms induced by hyperoxia in the U937 cell line.
J. Biochem. Mol. Biol., 37 (2004) 454-459.
131) M.T. Sanna, A. Olianas, M. Castagnola, L. Sollai, B. Manconi, S. Salvadori, B. Giardina, M.
Pellegrini.
Oxygen-binding modulation of hemocyanin from the slipper lobster Scyllarides latus.
Comp. Biochem. Physiol. B. Biochem. Mol. Biol., 139 (2004) 261-268.
13
132) R. Inzitari, T. Cabras, G. Onnis, C. Olmi, A. Mastinu, M.T. Sanna, M. Pellegrini, M.
Castagnola, I. Messana
Different isoforms and post-translational modifications of human salivary acidic proline-rich
proteins.
Proteomics, 5 (2005) 805-815.
133) M.T. Sanna B. Manconi, M. Castagnola, B. Giardina, D. Masia, I. Messana, A. Olianas, M.
Patamia, R. Petruzzelli, M. Pellegrini.
Functional and structural characterization of the myoglobin from the polychaete Ophelia bicornis.
Biochem. J., 389 (2005) 497-505.
134) M. Patamia, I. Messana, R. Petruzzelli, A. Vitali, R.Inzitari, T. Cabras, C. Fanali, E. Scarano,
A. Contucci, A. Gualtieri, M. Castagnola.
Two proline-rich peptides from pig (Sus scrofa) salivary glands generated by a pre-secretory
pathway underlying the action of a proteinase cleaving Pro-Ala bonds.
Peptides 26 (9), (2005) 1550-1559.
135) A. Olianas, I. Messana, M.T. Sanna, M. Castagnola, B. Manconi, D. Masia, E. Coluccia, B.
Giardina, M. Pellegrini.
Two sites for GTP binding in cathodic haemoglobins from Anguilliformes.
Comp. Biochem. Physiol. B. Biochem. Mol. Biol., 141 (2005) 400-407.
136) C. Santonocito, P. Concolino, M.M. Lavieri, F. Ameglio, S. Gentileschi, R. Capizzi, S.
Rocchetti, P. Amerio, M. Castagnola, C. Zuppi, E. Capoluongo.
Comparison between three molecular methods for the detection of blood melanoma tyrosinase
mRNA. Correlation with melanoma stages and S100B, LDH, NSE biochemical markers.
Clin. Chim. Acta, 362 (2005) 85-93.
137) E. Pisano, T. Cabras, C. Montaldo, V. Piras, R. Inzitari, C. Olmi, M. Castagnola, I. Messana.
Peptides of human gingival crevicular fluid determined by HPLC-ESI-MS.
Eur. J. Oral Sci. 113 (2005) 462-468.
138) E. Capoluongo, G. Vento, F. Ameglio, F. Lulli, P.G. Matassa, C. Carrozza, S.A. Santini, M.
Antenucci, M. Castagnola, B. Giardina, C. Romagnoli, C. Zuppi.
Increased levels of IGF-1 and beta2-microglobulin in epithelia lining fluid in preterm newborns
developing chronic lung disease. Effects of rhG-CSF.
Int. J. Immunopathol. Pharmacol. 19 (2006) 57-66.
139) A. Olianas, M.T. Sanna, I. Messana, M. Castagnola, M. Masia, B. Manconi, A. Cau, B.
Giardina, M. Pellegrini.
The hemocyanin of the shamefaced crab Calappa granulata: structural-functional characterization.
J. Biochem. (Tokyo), 139 (2006) 957-966.
140) T. Cabras, R. Inzitari, C. Fanali, E. Scarano, M. Patamia, M. T. Sanna, E. Pisano, B. Giardina,
M. Castagnola, I. Messana.
HPLC-MS characterization of cyclo-statherin Q-37, a specific cyclization product of human
salivary statherin generated by transglutaminase 2.
J. Sep. Sci. 29 (2006) 2600-2608.
14
141) R. Inzitari, T. Cabras, D. V. Rossetti, C. Fanali, A. Vitali, M. Pellegrini, G. Paludetti, A.
Manni, B. Giardina, I. Messana, M. Castagnola.
Detection in human saliva of different statherin and P-B fragments and derivatives.
Proteomics 6 (2006) 6370-6379.
142) C. Desiderio, A. Mancinelli, A. De Rossi, D. V. Rossetti, R. Inzitari, I. Messana, B. Giardina,
M. Castagnola.
Rapid determination of short chain carnitines in human plasma by elecrospray-ionization mass
spectrometry using capillary electrophoresis instrument as sampler.
J. Chromatogr. A 1150 (2007) 320-326.
143) R. Inzitari, G. Vento, E. Capoluongo, S. Boccacci, C. Fanali, T. Cabras, C. Romagnoli, B.
Giardina, I. Messana, M. Castagnola.
Proteomic analysis of salivary acidic proline-rich proteins in human pre-term and at-term newborns.
J. Proteome Res. 6 (2007) 1371-1377.
144) B. Manconi, A. Olianas, M.T. Sanna, I. Messana, L. Demurtas, M. Castagnola, B. Giardina,
M. Pellegrini.
Functional characterization of the single hemoglobin of the migratory bird Ciconia ciconia.
Comp. Biochem. Physiol B Biochem. Mol. Biol. 147 (2007) 242-249.
145) T. Cabras, M. Patamia, S. Melino, R. Inzitari, I. Messana, M. Castagnola, R. Petruzzelli
Pro-oxidant activity of histatin 5 related Cu(II)-model peptides probed by mass spectrometry.
Biochem. Biophys. Res. Comm. 358 (2007) 277-284.
146) T. Cabras, C. Fanali, J. A. Monteiro, F. Amado, R. Inzitari, C. Desiderio, B. Giardina, M.
Castagnola, I. Messana
Tyrosine polysulfation of human salivary histatin 1. A post-translational modification specific of
the submandibular gland.
J. Proteome Res. 6 (2007) 2472-2480.
147) G. Peluso, M. De Santis, R. Inzitari, C. Fanali, T. Cabras, I. Messana, M. Castagnola, G.F.
Ferraccioli
Proteomic study of salivary peptides and proteins in patients with Sjögren syndrome before and
after pilocarpine treatment
Arthritis & Rheumatism, 56 (2007) 2216-2222.
148) R. Brunelli, M. Papi, G. Arcovito, A. Bompiani, M. Castagnola, T. Parasassi, B. Sampaolese,
F. Vincenzoni, M. De Spirito
Globular structure of ovulatory cervical mucus
FASEB J 21 (2007) 3872-3876.
149) M.T. Sanna, B. Manconi, G. Podda, A. Olianas, M. Pellegrini, M. Castagnola, I. Messana, B.
Giardina
Alkaline Bohr effect of bird hemoglobins: the case of the flamingo
Biol. Chem. 388 (2007) 787-795.
15
150) T. Cabras, R. Longhi, F. Secundo, G. Nocca, S. Conti, L. Polonelli, C. Fanali, R. Inzitari, R.
Petruzzelli, I. Messana, M. Castagnola, A. Vitali.
Structural and functional characterization of the porcine proline-rich antifungal peptide SP-B
isolated from salivary gland granules.
J. Pept. Sci. 14 (2008) 251-260.
151) G. Podda, B. Manconi, A. Olianas, M. Pellegrini, I. Messana, M. Mura, M. Castagnola, B.
Giardina, M. T. Sanna.
Structural and functional characterization of hemocyanin from the anemone hermit crab Dardanus
Calidus.
J. Biochem. (Tokyo), 143 (2008) 207-216.
152) I. Messana, T. Cabras, E. Pisano, M. T. Sanna, A. Olianas, B. Manconi, M. Pellegrini, G.
Paludetti, E. Scarano, A. Fiorita, S. Agostino, A. M. Contucci, L. Calò, P. M. Picciotti, A. Manni,
A. Bennick, A. Vitali, C. Fanali, R. Inzitari, M. Castagnola.
Trafficking and post-secretory events responsible for the formation of secreted human salivary
peptides. A proteomic approach.
Mol. & Cell. Proteomics, 7 (2008) 911-926.
153) D. Rigante, R. Inzitari, M. Carone, C. Fanali, A. Stabile, T. Cabras, E. Capoluongo, S.
Gaspari, G. Barone, M. Castagnola.
Correspondence between clinical improvement and proteomic changes of the salivary peptide
complex in a child with a primary Sjögren syndrome.
Rheumatol. Int. 28 (2008) 801-806.
154) C. Fanali, R. Inzitari, T. Cabras, A. Fiorita, E. Scarano, M. Patamia, R. Petruzzelli, A.
Bennick, I. Messana, M. Castagnola.
Mass spectrometry strategies applied to the characterization of proline-rich peptides from secretory
parotid granules of pig (Sus scrofa).
J. Sep. Sci. 31 (2008) 516-522.
155) C. Desiderio, A. De Rossi, R. Inzitari, A. Mancinelli, D.V. Rossetti, M. Castagnola, I.
Messana.
Optimization of a rapid capillary electrophoresis ESI-IT tandem mass spectrometry method for the
analysis of short chain carnitines in human plasma.
Anal. Bioanal. Chem. 390 (2008) 1637-1644.
156) I. Messana, R. Inzitari, C. Fanali, T. Cabras, M. Castagnola.
Facts and artifacts in proteomics of body fluids. What proteomics of saliva is telling us?
J. Sep. Sci. 31 (2008) 1948-1963.
157) T. Cabras, M. Castagnola, R. Inzitari, J. Ekström, M. Isola, A. Riva, I. Messana.
Carbachol-induced in vitro secretion of certain human submandibular proteins investigated by mass
spectrometry.
Arch. Oral. Biol. 53 (2008) 1077-1083.
158) C. Desiderio, D.V. Rossetti, F. Perri, B. Giardina, I. Messana, M. Castagnola
Enantiomeric separation of baclofen by capillary electrophoresis tandem mass spectrometry with
sulfobutylether-beta-cyclodextrin as chiral selector in partial filling mode.
J Chromatogr. B, Analyt. Technol. Biomed. Life Sci. 875 (2008) 280-287.
16
159) A. Minucci, E. Delibato, M. Castagnola, P. Concolino, F. Ameglio, C. Zuppi, B. Giardina, E.
Capoluongo
Identification of RFLP G6PD mutations by using microcapillary electrophoretic chips
(Experion(TM)).
J. Sep. Sci. 31 (2008) 2694-2700.
160) M. Castagnola, I. Messana, R. Inzitari, C. Fanali, T. Cabras, A. Morelli, A.M. Pecoraro, G.
Neri, M.G. Torrioli, F. Gurrieri.
Hypo-phosphorylation of salivary peptidome as a clue to the molecular pathogenesis of autism
spectrum disorders.
J. Proteome Res. 7 (2008) 5327-5332.
161) C. Fanali, R. Inzitari, T. Cabras, E. Pisano, M. Castagnola, R. Celletti, A. Manni, I. Messana
α-Defensins levels in whole saliva of totally edentulous subjects
Int. J Immunopath. Pharmacol. 21 (2008) 845-849.
162) A. Olianas, B. Manconi, D. Masia, M.T. Sanna, M. Castagnola, S. Salvadori, I. Messana, B.
Giardina, M. Pellegrini
The oxygen-binding modulation of hemocyanin from the Southern spiny lobster Palinurus
Gilchristi.
J. Comp. Physiol. B 179 (2009) 193-203.
163) R. Inzitari, T. Cabras, E. Pisano, C. Fanali, B. Manconi, E. Scarano, A. Fiorita, G. Paludetti, A.
Manni, S. Nemolato, G. Faa, M. Castagnola, I. Messana.
HPLC-ESI-MS analysis of oral human fluids reveals that gingival crevicular fluid is the main
source of thymosins beta4 and beta10.
J. Sep. Sci. 32 (2009) 57-63.
164) S. Nemolato, I. Messana, T. Cabras, B. Manconi, R. Inzitari, C. Fanali, G. Vento, C. Tirone, C.
Romagnoli, A. Riva, D. Fanni, E. Di Felice, G. Faa, M. Castagnola.
Thymosin 4 and 10 levels in pre-term newborn oral cavity and foetal salivary glands evidence a
switch of secretion during foetal development.
PLoS ONE 4 (2009) e5109.
165) B. Manconi, I. Messana, F. Maggiani, A. Olianas. M. Pellegrini, R. Crnjar, M. Castagnola, B.
Giardina, M.T. Sanna.
Structural and functional characterization of Delphinus Delphi hemoglobin system.
J. Comp. Physiol. B 179 (2009) 971-983.
166) T. Cabras, E. Pisano, R. Boi, A. Olianas, B. Manconi, R. Inzitari, C. Fanali, B. Giardina, M.
Castagnola, I. Messana.
Age-dependent modifications of the human salivary secretory complex.
J. Proteome Res. 8 (2009) 4126-4134.
167) J. Ekström, M. Murakami, R. Inzitari, N. Khosravani, C. Fanali, T. Cabras, J. FujitaYoshigaki, H. Sugiya, I. Messana, M. Castagnola.
RP-HPLC-ESI-MS characterization of novel peptide fragments related to rat parotid secretory
protein in parasympathetic induced saliva.
J. Sep. Sci. 32 (2009) 2944-2952.
17
168) M. Bozzi, R. Inzitari, D. Sbardella, S. Monaco, E. Pavoni, M. Gioia, S. Marini, S. Morlacchi,
F. Sciandra, M. Castagnola, B. Giardina, A. Brancaccio, M. Coletta.
Enzymatic processing of beta-destroglycan recombinant ectodomain by MMP-9: identification of
the main cleavage site.
IUBMB Life, 61 (2009) 1143-1152.
169) G. Vento, C. Tirone, P. Lulli, E. Capoluongo, F. Ameglio, S. Lozzi, F. Cota, F. Mosca, C.
Romagnoli, I. Messana, M. Castagnola, R. Inzitari.
Bronchoalveolar lavage fluid peptidomics suggests a possible matrix metalloproteinase-3 role in
bronchopulmonary dysplasia.
Intensive Care Med 35 (2009) 2115-2124.
170) E. Delibato, A. Gattuso, A. Minucci, B. Auricchio, D. De Medici, L. Toti, M. Castagnola, E.
Capoluongo, M.V. Gianfranceschi.
PCR experion automated electrophoresis system to detect Lysteria monocytogenes in food.
J. Sep. Sci. 32 (2009) 3817-3821.
171) B. Manconi, T. Cabras, A. Vitali, C. Fanali, A. Fiorita, R. Inzitari, M. Castagnola, I. Messana,
M.T. Sanna.
Expression, purification, phosphorylation and characterization of recombinant human statherin.
Protein Expr. Purif. 69 (2010) 219-225.
172) S. Nemolato, T. Cabras, F. Cau, M.U. Fanari, D. Fanni, B. Manconi, I. Messana, M.
Castagnola, G. Faa.
Different thymosin beta 4 immunoreactivity in foetal and adult gastrointestinal tract.
PLoS One 5 (2010) e9111.
173) S. Nemolato, T. Cabras, M.U. Fanari, F. Cau, M. Fraschini, B. Manconi, I. Messana, M.
Castagnola, G. Faa.
Thymosin beta 4 expression in normal skin, colon mucosa and in tumor infiltrating mast cells.
Eur. J. Histochem. 54 (2010) e3.
174) C. Desiderio, D.V. Rossetti, I. Messana, B. Giardina, M. Castagnola.
Analysis of arginine and methylated metabolites in human plasma by field amplified sample
injection capillary electrophoresis tandem mass spectrometry
Electrophoresis 31 (2010) 1894-1902.
175) C. Tirone, S. Boccacci, R. Inzitari, M. Tana, C. Aurilia, C. Fanali, T. Cabras, I. Messana, M.
Castagnola, C. Romagnoli, G. Vento.
Correlation of the levels of alpha-defensins determined by HPLC-ESI-MS in bronchoalveolar
lavage fluid with the diagnosis of pneumonia in premature neonates.
Pediatr. Res. 68 (2010) 140-144.
176) G. Ferraccioli, M. De Santis, G. Peluso, R. Inzitari, C. Fanali, S.L. Bosello, F. Iavarone, M.
Castagnola.
Proteomic approaches to Sjögren’s syndrome: a clue to interpret the pathophysiology and organ
involvement of the disease.
Autoimmun. Rev. 9 (2010) 622-626.
18
177) B. Manconi, C. Fanali, T. Cabras, R. Inzitari, M. Patamia, E. Scarano, A. Fiorita, A. Vitali, M.
Castagnola, I. Messana, M.T. Sanna
Structural characterization of a new statherin from pig parotid granules.
J. Pept. Sci. 16 (2010) 269-275.
178) C. Desiderio, F. Iavarone, D.V. Rossetti, I. Messana, M. Castagnola.
Capillary electrophoresis-mass spectrometry for the analysis of amino acids.
J. Sep. Sci. 33 (2010) 2385-2393.
179) T. Cabras, E. Pisano, A. Mastinu, G. Denotti, P.P. Pusceddu, R. Inzitari, C. Fanali, S.
Nemolato, M. Castagnola, I. Messana.
Alteration of the salivary peptidome profile in children affected by type 1 diabetes.
Mol. Cell. Proteomics 9 (2010) 2099-2108.
180) B. Manconi, T. Cabras, E. Pisano, S. Nemolato R. Inzitari, F. Iavarone, C. Fanali, M.T. Sanna,
C. Tirone, G. Vento, C. Romagnoli, G. Faa, M. Castagnola, I. Messana.
Characterization of two isoforms of SPRR3 from preterm human newborn saliva, autoptic fetal oral
mucosa, parotid and submandibular gland samples.
Biochem. Biophys. Res. Comm. 398 (2010) 477-481.
181) M. Castagnola, I. Messana, M.T. Sanna, B. Giardina.
Oxygen-linked modulation of erythrocyte metabolism: state of the art.
Blood Transfus. 8 (Suppl. 3) (2010) s53-s58.
182) B.L. Pettorini, R. Inzitari, L. Massimi, G. Tamburrini, M. Caldarelli, C. Fanali, T. Cabras, I.
Messana, M. Castagnola, C. Di Rocco.
The role of inflammation in the genesis of the cystic component of craniopharyngiomas.
Childs Nerv. Syst. 26 (2010) 1779-1784.
183) C. Desiderio, D.V. Rossetti, F. Iavarone, I. Messana, M. Castagnola.
Capillary electrophoresis-mass spectrometry: recent trends in clinical proteomics.
J. Pharm. Biomed. Anal. 15(53) (2010) 1161-1169.
184) E. Scarano, A. Fiorita, P.M. Picciotti, G.C. Passali, L. Calo’, T. Cabras, R. Inzitari, C. Fanali,
I. Messana, M. Castagnola, G. Paludetti.
Proteomics of saliva: personal experience.
Acta Otorhinolaryngol. Ital., 30 (2010) 125-130.
185) C. Gerosa, D. Fanni, S. Nemolato, A. Locci, V. Marinelli, T. Cabras, I. Messana, M.
Castagnola, G. Monga, V. Fanos, G. Faa.
Thymosin beta 10 expression in developing human kidney.
J. Matern. Fetal Neonatal Med., 23 (2010) 125-128.
186) G. Vento. C. Tirone, C. Aurilia, M. Tana, A. Piras, A. Lio, G. Tesgafabir, M. Castagnola, C.
Fanali, C. Romagnoli.
Proteomics and neonatal infection.
Minerva Pediatr. 62 (2010) 47-49.
19
187) A. D’Addessi, L. Buongiovanni, M. Vittori, C. Fanali, N. Foschi, M. Castagnola, P.F. Bassi.
Calcium oxalate nephrolithiasis: urinary “medium size peptides” analysis using MALDI-TOF mass
spectrometry.
Arch. Ital. Urol. Androl. 82 (2010) 140-144.
188) S. Nemolato, T. Cabras, M.U. Fanari, F. Cau, D. Fanni, C. Gerosa, B. Manconi, I. Messana,
M. Castagnola, G. Faa.
Immunoreactivity of thymosin beta 4 in human foetal and genitourinary tract.
Eur. J. Histochem. 54 (2010) e43.
189) A. Olianas, C. Meloni, I. Messana, M.T. Sanna, M. Castagnola, B. Manconi, S. Salvadori, B.
Giardina, M. Pellegrini.
Striped mullet (Mugil cephalus) hemoglobin system: multiplicity and functional properties.
J. Comp. Physiol. B 181 (2011) 187-197.
190) E. De Carolis, B. Posteraro, A.R. Florio, B. Colonna, G. Prosseda, F. Bugli, S.R. Lorenzetti, E.
Fiscarelli, R. Inzitari, F. Iavarone, M. Castagnola, G. Fadda, M. Sanguinetti.
Analysis of heat induced changes in protein expression of Stenotrophomonas malthofilia K279a
reveals a role for GroEL in the host-temperature adaptation.
Int. J. Med. Microbiol. 301 (2011) 273-281 .
191) M. Castagnola, R. Inzitari, C. Fanali, F. Iavarone, A. Vitali, C. Desiderio, G. Vento, C.
Tirone, C. Romagnoli, T. Cabras, B. Manconi, M.T. Sanna, R. Boi, E. Pisano, A. Olianas, M.
Pellegrini, S. Nemolato, C.W. Heizmann, G. Faa, I. Messana.
The surprising composition of the salivary proteome of preterm human newborn.
Mol. Cell. Proteomics 10 (2011) M110.003467.
192) A. Urbani, A. Modesti, A.M. Timperio, L. Bini, M. Castagnola, M. Fasano, P. Roncada
Proteomics and renaissance: accounts of the V Italian Proteomics Association Congress. Florence
2010 (Editorial).
Mol. Biosyst. 7 (2011) 577-578.
193) M. De Santis, R. Inzitari, S.L. Bosello, G. Peluso, C. Fanali, F. Iavarone, G. Zizzo, M. Bocci,
T. Cabras, I. Messana, L. Fuso, F. Varone, G. Pagliari, M. Castagnola, G. Ferraccioli.
Beta-thymosin and interstitial lung disease: study of a scleroderma cohort with a one-year followup.
Respir. Res. 12 (2011) 22.
194) Castagnola M., Cabras T., Vitali A., Sanna M.T., Messana I.
Biotechnological implication of the salivary proteome.
Trends Biotechnol. 29 (2011) 409-418.
195) Fanni D., Gerosa C., Nemolato S., Locci A., Marinelli V. Cabras T. Messana I., Fanos V.,
Castagnola M., Faa G.
Thymosin beta 10 expression in developing human salivary glands.
Early Hum. Dev. 87(12) (2011) 779-783.
20
196) Persichilli S., Gervasoni J. Castagnola M., Zuppi C. Zappacosta B.
A reversed-phase HPLC fluorimetric method for the simultaneous determination of homocysteinerelated thiols in different body fluids.
Labmedicine 42 (2011) 657-662.
197) Nemolato S., Van Eyken P., Cabras T. Cau S., Fanari M.U., Locci A., Gerosa C., Messana I.,
Castagnola M., Faa G.
Expression pattern of thymosin beta 4 in the adult human liver.
Eur. J. Histochem. 55 (2011) e25
198) Castagnola M., Picciotti P.M., Messana I., Fanali C., Fiorita A., Cabras T., Calò L., Pisano E.,
Passali G.C., Iavarone F., Paludetti G., Scarano E.
Potential application of human saliva as diagnostic fluid.
Acta Otorhinolaryngol. Ital., 31 (2011) 347-357.
199) Milardi D., Grande G., Vincenzoni F., Messana I., Pontecorvi A., De Marinis L., Castagnola
M., Marana R.
Proteomic approach in the identification of fertility pattern in seminal plasma of fertile men.
Fertil. Steril. 97 (2012) 67-73; e1.
200) Cabras T., Manconi B., Iavarone F., Fanali C., Nemolato S., Fiorita A., Scarano E., Passali
G.C., Manni A., Cordaro M., Paludetti G., Faa G., Messana I., Castagnola M.
RP-HPLC-ESI-MS evidenced that salivary cystatin B is detectable in adult human saliva mostly as
S-modified derivatives: S-glutathionyl, S-cysteinyl and S-S 2-mer.
J. Proteomics 75 (2012) 908-913.
201) Nemolato S., Restivo A., Cabras T, Coni P, Zorcolo R., Fanari M., Orrù G., Cau F., Gerosa C.,
Fanni D., Messana I., Castagnola M., Casula G., Faa G.
Thymosin beta 4 in colorectal cancer is localized predominantly at the invasion front in tumor cells
undergoing epithelial mesenchimal transition.
Cancer Biol. Ther. 13(4) (2012) 191-197.
202) Castagnola M., Cabras T., Iavarone F., Fanali C., Nemolato S. Peluso G., Bosello S.L., Faa
G., Ferraccioli G., Messana I.
The human salivary proteome: a critical overview of the results obtained by different proteomic
platforms.
Expert Rev. Proteomics 9(1) (2012) 33-46.
203) Cabras T., Melis M., Castagnola M., Padiglia A., Tepper B.J., Messana I. Tomassini
Barbarossa I.
Responsiveness to 6-n-propylthiouracil (PROP) is associated with salivary levels of two specific
basic proline-rich proteins in humans.
PLoS ONE 7(2) (2012) e30962.
204) Urbani A., Modesti A., Timperio A.M., Bini L., Castagnola M., Fasano M., Roncada P.
Integrative proteomics: perspectives in complex system interpretation.(Editorial)
Mol. Biosyst. 8(4) (2012) 951-952.
21
205) De Santis M.D., Bosello S.L., Capoluongo E., Inzitari R., Peluso G. Lulli P. Zizzo G., Bocci
M., Tolusso B., Zuppi C., Castagnola M., Ferraccioli G.
A vascular endothelial growth factor deficiency characterizes scleroderma lung disease.
Ann. Rheum. Dis. 71 (2012) 1461-1465.
206) Desiderio C, D’Angelo L, Rossetti D.V., Iavarone F., Giardina B., Castagnola M., Massimi
L., Tamburrini G., Di Rocco C.
Cerebrospinal fluid top-down proteomics evidenced the potential biomarker role of LVV- and VV_
emorphin-7 in posterior cranial fossa paediatric tumours.
Proteomics 12 (2012) 2158-2166.
207) Cabras T., Boi R., Pisano E., Iavarone F., Fanali C., Nemolato S., Faa G., Castagnola M,
Messana I.
HPLC-ESI-MS and MS/MS structural characterization of multifucosylated N-glycoforms of the
basic proline-rich protein IB-8a CON1(+) in human saliva.
J. Sep. Sci. 35 (2012) 1079-1086.
208) Zeccola M, Longhi R, Rossetti DV, D’Angelo L, Tamburrini G, Di Rocco C, Giardina B,
Castagnola M, Desiderio C
Development and validation of a capillary electrophoresis tandem mass spectrometry analytical
method for the determination of LVV- and VV-hemorphin-7 peptides in cerebrospinal fluid.
J. Chromatogr. A 1267 (2012) 170-177.
209) Faa G., Fanni D., Gerosa C., Nemolato S., Gibo Y., Castagnola M., Fanos V.
Drug-induced liver injury in neonates: a developmental approach.
In “Perinatal pharmacology: individualized neonatal therapy” pp. 49-81.
J.V. Aranda, V. Fanos, J.N. van der Anker Eds., Hygeia Press, Cagliari, Italy, 2012.
210) Faa G, Nemolato S, Cabras T, Fanni D, Gerosa C, Fanari M, Locci A, Fanos V, Messana I,
Castagnola M.
Thymosin β4 expression reveals intriguing similarities between fetal and cancer cells.
Ann. N. Y. Acad. Sci. 1269(1) (2012) 53-60.
211) Castagnola M, Cabras T, Iavarone F, Vincenzoni F, Vitali A, Pisano E, Nemolato S, Scarano
E, Fiorita A, Vento G, Tirone C, Romagnoli C, Cordaro M, Paludetti G, Faa G, Messana I.
Top-down platform for deciphering the human salivary proteome.
J. Matern. Fetal Neonatal Med. 25 (Suppl 5) (2012) 27-43.
212) Faa G, Ekstrom J, Castagnola M, Gibo Y, Ottonello G, Fanos V.
A Developmental Approach to Drug-induced Liver Injury in Newborns and Children.
Curr Med Chem. 19(27) (2012) 4581-4594.
213) Sbardella D, Inzitari R, Iavarone F, Gioia M, Marini S, Sciandra F, Castagnola M, Van den
Steen PE, Opdenakker G, Giardina B, Brancaccio A, Coletta M, Bozzi M.
Enzymatic processing by MMP-2 and MMP-9 of wild-type and mutated mouse β-dystroglycan.
IUBMB Life 64(12) (2012) 988-994.
22
214) Massimo Castagnola, Irene Messana, Tiziana Cabras, Federica Iavarone, Chiara Fanali,
Alessandra Morelli, Anna Maria Pecoraro, Giovanni, Neri, Maria Giulia Torrioli, Fiorella Gurrieri.
Hypo-phosphorylation of salivary peptidome as a clue of the molecular pathogenesis of autism
spectrum disorders
In The Comprehensive Guide to Autism · V.B.Patel, V.R.Preedy, C.R. Martin Eds. Springer,
London 2012 - Article ID: 331196 · Chapter ID: 87
215) Ekström, J., Khosravani, N., Castagnola M., Messana I.
Saliva and the control of its secretion
In “Dysphagia. Diagnosis and treatment.” Olle Ekberg Ed., In Medical Radiology & Diagnostic
Imaging Series. Reiser M.F., Hricak, H., Knauth, M. Eds., Springer-Verlag, Berlin-Heidelberg –
2012. Part I, Chapter 2, pp. 19-48.
216) Chiusolo P, Metafuni E, Giammarco S, Bellesi S, Piccirillo N, Fanali C, Castagnola M, Zuppi
C, De Michele T, Leone G, Sica S.
Role of fecal calprotectin as biomarker of gastrointestinal GVHD after allogeneic stem cell
transplantation.
Blood 120(22) (2012) 4443-4444.
217) Messana I, Cabras T, Iavarone F, Vincenzoni F, Urbani A, Castagnola M
Unraveling the different proteomic platforms.
J Sep Sci. 36 (2013) 128-139.
218) de Sousa Pereira P, Abrantes J, Colaço B, Castagnola M, Amado F, Esteves PJ, Vitorino R
Characterization of thymosin β4 in mammals’ saliva.
Peptides 40 (2013) 1-7.
219) Conti S, Radicioni G, Ciociola T, Longhi R, Polonelli L, Gatti R, Cabras T, Messana I,
Castagnola M, Vitali A.
Structural and functional studies on a proline-rich peptide isolated from swine saliva endowed with
antifungal activity towards Cryptococcus neoformans.
Biochim Biophys Acta, 1828(3) (2013) 1066-1074.
220) Iavarone F, Cabras T, Pisano E, Sanna MT, Nemolato S, Vento G, Tirone C, Romagnoli C,
Cordaro M, Fanos V, Faa G, Messana I, Castagnola M.
Top-down HPLC-ESI-MS detection of S-glutathionylated and S-cysteinylated derivatives of
cystatin B and its 1-53 and 54-98 fragments in whole saliva of human pre-term newborns.
J Proteome Res. 12(2) (2013) 917-926.
221) Castagnola M, Cabras T, Iavarone F, Fanali C, Messana I
Detection of Ca(2+)-binding S100 proteins in human saliva by HPLC-ESI-MS.
Methods Mol. Biol. 963 (2013) 357-371.
(in “Calcium binding proteins and RAGE: from Structural Basics to Clinical Applications” C.W.
Heizmann Ed. –. Humana Press- New York.)
222) Desiderio C, Martelli C, Rossetti DV, Di Rocco C, D'Angelo L, Caldarelli M, Tamburrini G,
Iavarone F, Castagnola M, Messana I, Cabras T, Faa G.
Identification of thymosin β4 and β10 in paediatric craniopharingioma cystic fluid.
Childs Nerv Syst. 29(6) (2013) 951-960.
23
223) Chiusolo P, Giammarco S, Fanali C, Bellesi S, Metafuni E, Sica S, Iavarone F, Cabras T,
Messana I, Leone G, Castagnola M.
Salivary proteomic analysis and acute graft versus host disease after allogeneic hematopoietic stem
cell transplantation.
Biol Blood Marrow Transplant. 19(6) (2013) 888-892.
224) Cabras T, Pisano E, Montaldo C, Giuca MR, Iavarone F, Zampino G, Castagnola M, Messana
I.
Significant modifications of the salivary proteome potentially associated with complications of
Down syndrome revealed by top-down proteomics.
Mol Cell Proteomics, 12(7) (2013) 1844-1852.
225) Melis M, Aragoni MC, Arca M, Cabras T, Caltagirone C, Castagnola M, Crnjar R, Messana I,
Tepper BJ, Tomassini-Barbarossa I
Marked Increase in PROP Taste Responsiveness Following Oral Supplementation with Selected
Salivary Proteins or Their Related Free Amino Acids.
PLoS One. 8(3), (2013), e59810.
226) Milardi D, Grande C, Vincenzoni F, Castagnola M, Marana R
Proteomics of human seminal plasma: identification of biomarker candidates for fertility and
infertility and evolution of technology.
Mol. Reprod. Dev. 80 (5) (2013) 350-357
227) Vento G, Lio A, Tirone C, Aurilia C, Tana M, Piras A, Ricci C, Perelli S, Romagnoli C,
Posteraro B, Iavarone F, Cabras T, Fanali C, Messana I, Castagnola M.
Association of high levels of α-defensins and S100A proteins with Candida mannan detection in
bronchoalveolar lavage fluid of preterm neonates.
Pediatr. Res. 74 (1) (2013) 19-25.
228) Urbani A, Castagnola M, Fasano M, Bini L, Modesti A, Timperio AM, Roncada P.
Digital and analogical reality in proteomics investigation.
Mol Biosyst. 9(6) (2013) 1062-1063.
229) Manconi B, Pellegrini M, Messana I, Sanna MT, Castagnola M, Iavarone F, Coluccia E,
Giardina B, Olianas A.
The hemoglobin system of the serpent eel Ophisurus serpens: structural and functional
characterization.
J Comp Physiol B. 183(7) (2013) 905-919.
230) Cabras T, Iavarone F, Pirolli D, De Rosa MC, Vitali A, Faa G, Cordaro M, Messana I,
Ekström J, Castagnola M.
Top-down HPLC-ESI-MS characterization of rat gliadoralin A, a new member of the family of rat
submandibular gland glx-rich proteins and potential substrate of transglutaminase.
J Sep Sci. 36(17) (2013) 2848-2861.
24
231) Urbani A, De Canio M, Palmieri F, Sechi S, Bini L, Castagnola M, Fasano M, Modesti A,
Roncada P, Timperio AM, Bonizzi L, Brunori M, Cutruzzolà F, De Pinto V, Di Ilio C, Federici G,
Folli F, Foti S, Gelfi C, Lauro D, Lucacchini A, Magni F, Messana I, Pandolfi PP, Papa S, Pucci P,
Sacchetta P.
The mitochondrial Italian Human Proteome Project initiative (mt-HPP).
Mol Biosyst. 9(8) (2013) 1984-1992.
232) Nemolato S, Ekstrom J, Cabras T, Gerosa C, Fanni D, Di Felice E, Locci A, Messana I,
Castagnola M, Faa G
Immunoreactivity for thymosin beta 4 and thymosin beta 10 in the adult rat oro-gastro-intestinal
tract.
Eur J Histochem. 57(2) (2013) e17.
233) Rossetti DV, Martelli C, Longhi R, Iavarone F, Castagnola M, Desiderio C.
Quantitative analysis of Thymosin β4 in whole saliva by Capillary Electrophoresis – Mass
Spectrometry using Multiple Ions Monitoring (CE-MIM-MS).
Electrophoresis, 34(18) (2013) 2674-2682.
234) Knop J, App C, Horn AH, Iavarone F, Castagnola M, Hannappel E.
High-Resolution HPLC-ESI-MS Characterization of the Contact Sites of the Actin-Thymosin β4
Complex by Chemical and Enzymatic Cross-Linking.
Biochemistry, 52(33) (2013) 5553-5562.
235) Pichiri G, Coni P, Nemolato S, Cabras T, Fanari MU, Sanna A, Di Felice E, Messana I,
Castagnola M, Faa G.
Cellular Trafficking of Thymosin Beta-4 in HEPG2 Cells Following Serum Starvation.
PLoS One 8(8) (2013) e67999.
236) Manconi B, Cabras T, Pisano E, Sanna MT, Olianas A, Fanos V, Faa G, Nemolato S, Iavarone
F, Castagnola M, Messana I.
Modifications of the acidic soluble salivary proteome in human children from birth to the age of 48
months investigated by a top-down HPLC-ESI-MS platform.
J Proteomics 91 (2013) 536-543.
237) Nemolato S, Cabras T, Restivo A, Zorcolo L, Di Felice E, Fanni D, Gerosa C, Messana I,
Castagnola M, Faa G, Casula G.
Thymosin ß4 expression in colorectal polyps and adenomas.
Clinics (Sao Paulo) 68(9) (2013) 1220-1224.
238) Cabras T, Iavarone F, Manconi B, Olianas A, Sanna MT, Castagnola M, Messana I.
Top-down analytical platforms for the characterization of the human salivary proteome.
Bioanalysis. 6(4) (2014) 563-581.
239) Fanni D, Ambu R, Gerosa C, Nemolato S, Castagnola M, Van Eyken P, Faa G, Fanos V.
Cytochrome P450 genetic polymorphism in neonatal drug metabolism: role and practical
consequences towards a new drug culture in neonatology.
Int. J. Immunopathol. Pharmacol. 27(1) (2014) 5-13.
25
240) Iavarone F, Melis M, Platania G, Cabras T, Manconi B, Petruzzelli R, Cordaro M, Siracusano
A, Faa G, Messana I, Zanasi M, Castagnola M
Characterization of salivary proteins of schizophrenic and bipolar disorder patients by top-down
proteomics.
J Proteomics 103 (2014) 15-22.
241) Theunissen W, Fanni D, Nemolato S, Di Felice E, Cabras T, Gerosa C, Van Eyken P, Messana
I, Castagnola M, Faa G.
Thymosin beta 4 and thymosin beta 10 expression in hepatocellular carcinoma.
Eur J Histochem. 58(1) (2014) 2242.
242) Martelli C, Iavarone F, Vincenzoni F, Rossetti DV, D'Angelo L, Tamburrini G, Caldarelli M,
Di Rocco C, Messana I, Castagnola M, Desiderio C.
Proteomic characterization of pediatric craniopharyngioma intracystic fluid by LC-MS topdown/bottom-up integrated approaches.
Electrophoresis. 35(15) (2014) 2171-2183.
243) App C, Knop J, Huff T, Seebahn A, Becker CM, Iavarone F, Castagnola M, Hannappel E.
Peptide labeling with photoactivatable trifunctional cadaverine derivative and identification of
interacting partners by biotin transfer.
Anal Biochem. 456 (2014) 14-21.
244) Iavarone F, D'Alessandro A, Tian N, Cabras T, Messana I, Helmerhorst EJ, Oppenheim FG,
Castagnola M.
High-resolution high-performance liquid chromatography with electrospray ionization mass
spectrometry and tandem mass spectrometry characterization of a new isoform of human salivary
acidic proline-rich proteins named Roma-Boston Ser22 (Phos) → Phe variant.
J Sep Sci. 37(14) (2014) 1896-1902.
245) Roncada P, Modesti A, Timperio AM, Bini L, Castagnola M, Fasano M, Urbani A.
One medicine - one health - one biology and many proteins: proteomics on the verge of the One
Health approach.
Mol Biosyst. 10(6) (2014) 1226-1227.
246) Milardi D, Grande G, Vincenzoni F, Giampietro A, Messana I, Castagnola M, Marana R, De
Marinis L, Pontecorvi A.
Novel biomarkers of androgen deficiency from seminal plasma profiling using high-resolution mass
spectrometry.
J. Clin Endocrinol Metab. 99(8) (2014) 2813-2820.
247) Fanni D, Fanos V, Ambu R, Lai F, Gerosa C, Pampaloni P, Van Eyken P, Senes G,
Castagnola M, Faa G.
Overlapping between CYP3A4 and CYP3A7 expression in the fetal human liver during
development.
J Matern Fetal Neonatal Med. 10 (2014) 1-5.
248) Martelli C, Iavarone F, Vincenzoni F, Cabras T, Manconi B, Desiderio C, Messana I,
Castagnola M
Top-down peptidomics of bodily fluids.
Peptidomics 1 (2014) 47-64.
26
249) Inserra I, Iavarone F, Martelli C, D'Angelo L, Delfino D, Rossetti DV, Tamburrini G, Massimi
L, Caldarelli M, Di Rocco C, Messana I, Castagnola M, Desiderio C.
Proteomic Study of Pilocytic Astrocytoma Pediatric Brain Tumor Intracystic Fluid.
J Proteome Res. 13(11) (2014) 4594-4606.
250) Castagnola M, Uda F, Noto A, Fanos V, Faa G
The triple-I (interactive, intersectorial, interdisciplinary) approach to validate "omics" investigations
on body fluids and tissues in perinatal medicine.
J Matern Fetal Neonatal Med. 27 Suppl 2 (2014) 58-60.
251) Nemolato S, Cabras T, Messana I, Gerosa C, Faa G, Castagnola M.
Do β-thymosins play a role in human nephorgenesis?
in Kidney Development in Renal Pathology, G. Faa and V Fanos Ed.s; Current Clinical Pathology
Series Ed. A Giordano. Humana Press (Springer) – New York 2014. Chapter 8, pg 81-93.
252) Fabrini R, Bocedi A, Camerini S, Fusetti M, Ottaviani F, Passali FM, Topazio D, Iavarone F,
Francia I, Castagnola M, Ricci G.
Inactivation of Human Salivary Glutathione Transferase P1-1 by Hypothiocyanite: A PostTranslational Control System in Search of a Role.
PLoS One. 9(11), 2014, e112797.
253) Sanna M, Firinu D, Manconi PE, Pisanu M, Murgia G, Piras V, Castagnola M, Messana I,
Del Giacco SR, Cabras T.
The salivary proteome profile in patients affected by SAPHO syndrome characterized by a topdown RP-HPLC-ESI-MS platform.
Mol Biosyst. 11(6) (2015) 1552-1562 PMID: 25671558.
254) Tian N, Messana I, Leffler DA, Kelly CP, Hansen J, Cabras T, D'Alessandro A, Schuppan D,
Castagnola M, Helmerhorst EJ.
Salivary proline-rich proteins and gluten: Do structural similarities suggest a role in celiac disease?
Proteomics Clin. Appl. 9(9-10) (2015) 953-964 PMID: 25726832.
255) Messana I, Cabras T, Iavarone F, Manconi B, Huang L, Martelli C, Olianas A, Sanna MT,
Pisano E, Sanna M, Arba M, D'Alessandro A, Desiderio C, Vitali A, Pirolli D, Tirone C, Lio A,
Vento G, Romagnoli C, Cordaro M, Manni A, Gallenzi P, Fiorita A, Scarano E, Calò L, Passali GC,
Picciotti PM, Paludetti G, Fanos V, Faa G, Castagnola M.
Chrono-proteomics of human saliva: variations of the salivary proteome during human
development.
J Proteome Res. 14(4) (2015) 1666-1677.
256) Piludu M, Piras M, Pichiri G, Coni P, Orrù G, Cabras T, Messana I, Faa G, Castagnola M.
Thymosin beta 4 may translocate from the cytoplasm in to the nucleus in HepG2 cells following
serum starvation. An ultrastructural study.
PLoS One 10(3) (2015) e0119642.
257) Fanos V, Castagnola M, Faa G.
Prolonging nephrogenesis in preterm infants. A new approach for prevention of kidney disease in
adulthood?
Iran. J. Kidney Dis., 9 (2015) 180-185.
27
258) Martelli C, Iavarone F, D'Angelo L, Arba M, Vincenzoni F, Inserra I, Delfino D, Rossetti DV,
Caretto M, Massimi L, Tamburrini G, Di Rocco C, Caldarelli M, Messana I, Castagnola M, Sanna
MT, Desiderio C.
Integrated proteomic platforms for the comparative characterization of medulloblastoma and
pilocytic astrocytoma pediatric brain tumors: a preliminary study.
Mol Biosyst. 11(6) (2015) 1668-1683.
259) Urbani A, Roncada P, Modesti A, Timperio AM, Bini L, Fasano M, Castagnola M.
Inductive proteomics and large dataset collections.
Mol Biosyst. 11(6) (2015) 1485-1486.
260) Grande G, Milardi D, Vincenzoni F, Pompa G, Biscione A, Astorri AL, Fruscella E, De Luca
A, Messana I, Castagnola M, Marana R.
Proteomic characterization of the qualitative and quantitative differences in cervical mucus
composition during the menstrual cycle.
Mol Biosyst. 11(6) (2015) 1717-1725.
261) Cabras T, Iavarone F, Martelli C, Delfino D, Rossetti DV, Inserra I, Manconi B, Desiderio C,
Messana I, Hannappel E, Faa G, Castagnola M.
High resolution mass spectrometry for thymosins detection and characterization.
Expert Opin Biol Ther. 15 (Suppl.1) (2015) 191-201.
262) Knop J, App C, Huff T, Iavarone F, Castagnola M, Hannappel E.
Identification of PDGF-BB binding to thymosin β4 by chemical cross-linking.
Expert Opin Biol Ther. 15 (Suppl.1) (2015) 147-154.
263) Melis M, Arca M, Aragoni MC, Cabras T, Caltagirone C, Castagnola M, Crnjar R, Messana I,
Tepper BJ, Tomassini Barbarossa I.
Dose-dependent effects of L-arginine on PROP bitterness intensity and latency and characteristics
of the chemical interaction between PROP and L-arginine.
PLos One 10(6) (2015) e0131104.
264) Cabras T, Sanna M, Manconi B, Fanni D, Demelia L, Sorbello O, Iavarone F, Castagnola M,
Faa G, Messana I
Proteomic investigation of whole saliva in Wilson’s disease.
J Proteomics 128 (2015) 154-163.
265) Giorgia Radicioni, Annarita Stringaro, Agnese Molinari, Giuseppina Nocca, Renato Longhi,
Davide Pirolli, Emanuele Scarano, Federica Iavarone, Barbara Manconi, Tiziana Cabras, Irene
Messana, Massimo Castagnola, Alberto Vitali.
Characterization of the cell penetrating properties of a human salivary proline-rich peptide.
Biochimica et Biophysica Acta (BBA)-Biomembranes, 1848(11) (2015) 2868-2877.
266) Marta Alexandra Mendonça Nóbrega Cova, Massimo Castagnola, Irene Messana, Tiziana
Cabras, Rita Maria Pinho Ferreira, Francisco Manuel Lemos Amado, Rui Miguel Pinheiro Vitorino.
Salivary omics
In Advances in Salivary Diagnostics, C.F. Strekfus Ed., Springer Berlin Heidelberg, 2015, pp 63-82
28
267) Barbara Manconi, Massimo Castagnola, Tiziana Cabras, Alessandra Olianas, Alberto Vitali,
Claudia Desiderio, Maria Teresa Sanna, Irene Messana.
The intriguing heterogeneity of human salivary proline-rich proteins.
Journal of Proteomics (2015) in press PMID: 26375204
268) Inserra I, Martelli C, Cipollina M, Cicione C, Iavarone F, Taranto GD, Barba M, Castagnola
M, Desiderio C, Lattanzi W.
Lipoaspirate fluid proteome: A preliminary investigation by LC-MS top-down/bottom-up integrated
platform of a high potential biofluid in regenerative medicine.
Electrophoresis. (2015) in press PMID: 26719138
269) Chronopoulou L, Nocca G, Castagnola M, Paludetti G, Ortaggi G, Sciubba F, Bevilacqua M,
Lupi A, Gambarini G, Palocci C.
Chitosan based nanoparticles functionalized with peptidomimetic derivatives for oral drug delivery.
N. (New) Biotechnol. 33(1) (2016) 23-31.
270) Palmerini CA, Mazzoni M, Radicioni G, Marzano V, Granieri L, Iavarone F, Longhi R,
Messana I, Cabras T, Sanna MT, Castagnola M, Vitali A.
Antagonistic Effect of a Salivary Proline-Rich Peptide on the Cytosolic Ca2+ Mobilization Induced
by Progesterone in Oral Squamous Cancer Cells.
PLoS One. 11(1) (2016) e0147925. PMID:26814504
271) Manconi B, Cabras T, Sanna M, Piras V, Liori B, Pisano E, Iavarone F, Vincenzoni F,
Cordaro M, Faa G, Castagnola M, Messana I.
N- and O-linked glycosylation site profiling of the human basic salivary proline-rich protein 3M.
J Sep Sci. 2016 PMID: 26991339
272) Martelli C, Marzano V, Iavarone F, Huang L, Vincenzoni F, Desiderio C, Messana I, Beltrami
P, Zattoni F, Ferraro PM, Buchholz N, Locci G, Faa G, Castagnola M, Gambaro G.
Characterization of the protein components of matrix stones sheds light on the S100-A8 and A9
relevance in the inflammatory pathogenesis of these rare renal calculi.
J Urol. 2016 PMID:27113968
273) Righino B, Pirolli D, Radicioni G, Marzano V, Longhi R, Arcovito A, Sanna MT, De Rosa
MC, Paoluzi S, Cesareni G, Messana I, Castagnola M, Vitali A
Structural studies and SH3 domain binding properties of a human antiviral salivary proline-rich
peptide.
Biopolymers. 2016 PMID:27272460
274) Morena Arba, Federica Iavarone, Federica Vincenzoni, Barbara Manconi, Giovanni Vento,
Chiara Tirone, Tiziana Cabras, Massimo Castagnola, Irene Messana, Maria Teresa Sanna.
Proteomic characterization of the acid-insoluble fraction of whole saliva
from preterm human newborns
J. Proteomics 146 (2016) 48-57.
275) Vitali A, Vavala E, Marzano V, Leone C, Castagnola M, Iavarone F, Angiolella L.
Cell wall composition and biofilm formation of azoles-susceptible and -resistant Candida glabrata
strains.
J Chemother. 2016 in press PMID: 27439026
29
276) Faa G, Messana I, Fanos V, Cabras T, Manconi B, Vento G, Iavarone F, Martelli C, Desiderio
C, Castagnola M.
Proteomics applied to pediatric medicine: opportunities and challenges.
Expert Rev Proteomics. 2016, in press PMID:27498711
277) Bocedi A, Fabrini R, Pedersen JZ, Federici G, Iavarone F, Martelli C, Castagnola M, Ricci G.
The Extreme Hyper-Reactivity of Selected Cysteines Drives Hierarchical Disulfide Bond Formation
in Serum Albumin.
FEBS J. 2016 in press PMID: 27685835
278) Bosello S, Peluso G, Iavarone F, Tolusso B, Messana I, Faa G, Castagnola M, Ferraccioli G.
Thymosin β4 and β10 in Sjögren's syndrome: saliva proteomics and minor salivary glands
expression.
Arthritis Res Ther. 2016 Oct 6;18(1):229.
30