Apoptosis Signal–Regulating Kinase 1 Is a Novel Target
Molecule for Cognitive Impairment Induced by Chronic
Cerebral HypoperfusionSignificance
by Kensuke Toyama, Nobutaka Koibuchi, Ken Uekawa, Yu Hasegawa, Keiichiro
Kataoka, Tetsuji Katayama, Daisuke Sueta, Ming Jie Ma, Takashi Nakagawa, Osamu
Yasuda, Hidekazu Tomimoto, Hidenori Ichijo, Hisao Ogawa, and Shokei KimMitsuyama
Arterioscler Thromb Vasc Biol
Volume 34(3):616-625
February 19, 2014
Copyright © American Heart Association, Inc. All rights reserved.
The role of apoptosis signal–regulating kinase 1 (ASK1) in cognitive impairment induced by
chronic cerebral hypoperfusion.
Kensuke Toyama et al. Arterioscler Thromb Vasc Biol.
2014;34:616-625
Copyright © American Heart Association, Inc. All rights reserved.
Effect of cerebral hypoperfusion on apoptosis signal–regulating kinase 1 (ASK1) and p38
activation.
Kensuke Toyama et al. Arterioscler Thromb Vasc Biol.
2014;34:616-625
Copyright © American Heart Association, Inc. All rights reserved.
Effect of bilateral common carotid artery stenosis (BCAS) surgery on blood–brain barrier (BBB),
claudin-5, and tumor necrosis factor-α (TNF-α).
Kensuke Toyama et al. Arterioscler Thromb Vasc Biol.
2014;34:616-625
Copyright © American Heart Association, Inc. All rights reserved.
In vitro effect of cerebral hypoperfusion on cerebral nitrotyrosine and effect of oxygen-glucose
deprivation (OGD) conditions on cerebral endothelial cells.
Kensuke Toyama et al. Arterioscler Thromb Vasc Biol.
2014;34:616-625
Copyright © American Heart Association, Inc. All rights reserved.
Role of p38 and oxidative stress in cognitive impairment and blood–brain barrier (BBB)
breakdown induced by chronic cerebral hypoperfusion.
Kensuke Toyama et al. Arterioscler Thromb Vasc Biol.
2014;34:616-625
Copyright © American Heart Association, Inc. All rights reserved.
Effect of compound K811 on cognitive impairment induced by chronic cerebral hypoperfusion.
Kensuke Toyama et al. Arterioscler Thromb Vasc Biol.
2014;34:616-625
Copyright © American Heart Association, Inc. All rights reserved.