ATP
synthase
H+
Na+/phosphate
symporter
Pi
Unclassified transporters
Na+
ABC transporters
Fe2+
Metal
Drugs
Na+
Fe2+
Metal
Drugs
Na+
hn
PPi
ADP + Pi
Na+
ATP
PR
Glycolysis
Pentose phosphate cycle
H+
H+
Glucose-6-phosphate
Ribulose-5-phosphate
H+
Sedoheptulose-7phosphate
H+
PP
PPi
H+
Erythrose-4-phospahte
Pi
HQNO
NQR
H+
Glycerone-phosphate
z
Na+
3-Phospho-D-glycerate
NAD+
Succinate
SDH
HCO3-
Phosphoenolpyruvate
< 1.0
< 1.5
< 2.0
Oxaloacetate
Citrate
Malate
Pyruvate
L2/D4 ratio
1.0 ≤
1.5 ≤
2.0 ≤
CO2
Fumarate
Cyt c
Electron transport chain
Fructose-1, 6-diphosphate
Glyceraldenyde-3-phosphate
NADH
Na+
Fructose-6-phosphate
TCA cycle
Cyt bc1
CO2
HCO3-
H+
SO42-
K+
H+
SO42-
K+
Isocitrate
Fumarate
O2
H+
Succinate
Cyt aa3
H2O
Alanine
Na+
Na+
2-Oxoglutarate
SuccinylCoA
NHA
Alanine
Na+
Na+/alanine
symporter
Na+
Secondary transporters
Figure S5 Model of light-stimulated transcriptional responses in MED134. The color
allows and membrane proteins indicate the value of L2/D4 ratio. Proton and sodium
translocating processes are shown in left. 2-n-heptyl-4-hydroxyquinoline N-oxide (HQNO)
is a specific inhibitor of Na+-translocating NADH-quinone oxioreductase (NQR) that links
electron transport chain. PR, proteorhodopsin; PP, pyrophosphatase; SDH, succinate
dehydrogenase; Cyt, cytochrome oxidase; NHA, Na+/H+ antiporter.