HIFU – 3D Tissue Maps 3/31/17 CONFIDENTIAL 1 HIFU – 3D TISSUE MAPS Introduction o Calculating the thermal dose delivered by therapeutic treatments is dependant on many factors, and can be a complex process o PZFlex combines piezoelectric, acoustic, and thermal solvers to allow a true multiphysics analysis of large problems o This process can be accelerated using the new MPI module, turning round results even faster than before 3/31/17 CONFIDENTIAL 2 HIFU – 3D TISSUE MAPS PZFlex Capabilities o PZFlex is ideally suited for HIFU work, providing the following: o Non-linear time domain analysis o Load complex tissue maps from CAD or images o Coupled electromechanical analysis of transducers o Coupled or un-coupled thermal analysis o Model acceleration via MPI 3/31/17 CONFIDENTIAL 3 HIFU – 3D TISSUE MAPS Tissue Map Importation o Import tissue maps from CAD or image data directly to model Image of human abdomen, courtesy of The US National Library of Medicine's Visible Human project: http://www.nlm.nih.gov/research/visible/visib le_human.html 3/31/17 CONFIDENTIAL Imported PZFlex material map 4 HIFU – 3D TISSUE MAPS 3D Analysis o PZFlex can handle models with over 1 billion elements, allowing treatments to be simulated in full 3D 3D Model of abdomen section meshed for 200kHz with 40 million elements 3/31/17 CONFIDENTIAL 5 HIFU – 3D TISSUE MAPS Acoustic Solve 3/31/17 CONFIDENTIAL 6 HIFU – 3D TISSUE MAPS Acceleration Using MPI o MPI can be used to split models across multiple cores, and is much more efficient than traditional multithreaded execution o This example shows an acoustic model split into 16 slices o Speed increases of over 10x have been demonstrated using MPI 3/31/17 CONFIDENTIAL 7 SIMULATION METRICS PZFlex combines multiphysics capabilities with unprecedented speed to allow 3D simulation of treatments on standard desktop hardware Model 2D Model 3D Model Elements 1,400,000 40,000,000 Runtime Memory (RAM) 2 mins 22 s* 1 hr 15 mins* 205 MB 4.30 GB * Run on Dell Precision Tower 7810 3/31/17 CONFIDENTIAL 8 3/31/17 CONFIDENTIAL 9
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