Catabolic Pathways
2nd Year Physiotherapy
By
Eman Mokbel Alissa, Ph.D.
Lecture (1) Contents
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Metabolism Introduction
Thermodynamics
Catabolism and Anabolism
Metabolic Map
Examples of metabolic pathways
Lecture (2) Contents
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Bioenergetics Definition
Biomedical Importance
Central Reactions of Metabolism
ATP as energy carrier
ATP, ADP, and AMP structures
ATP / ADP Cycle
Types of Chemical Bonds
Mechanism of Energy Collection
Energy currency
Lecture (3) Contents
• Electron Transfer Chain (ETC)
• Chemiosmotic Hypothesis
• Conservation of ΔG from NADH oxidation
in a pH gradient
• Respiratory Control
Lecture (4) Contents
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Some Points About Glucose
Glucose Oxidation
Fate of Glucose
Glycolysis ATP and NADH production
Alternative Pathways of Pyruvate
TCA Cycle
Summary of ATP Produced
Lecture (5) Contents
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Fat and Fatty Acids
Fatty Acid Oxidation
β oxidation
ATP Generation from -Oxidation
β-oxidation in peroxisome
Unsaturated FA oxidation
FA oxidation with odd Carbon No.
α-oxidation
Lecture (6) Contents
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Amino acids introduction
N2 Metabolism
Overall flow of nitrogen in amino acid catabolism
Removal of Nitrogen
Combined actions of amintoransferase and
glutamate dehydrogenase reactions
• Ammonia transport to liver
• Urea Cycle
• Link between urea cycle and TCA cycle