Name: Period: GENETICS WEBQUEST: Blood Types Greetings, genetics students. In this webquest you will explore the genetics of human blood types. (You will work in groups of three on each computer if needed.) Use this guide as a record of your travels and accomplishments as you navigate the site. The force will be with you, always. Begin by navigating to http://www.biology.arizona.edu/ . Select the “Human Biology” link in the upper left hand corner under “Activities”. Click on “Blood Types” to begin. Read the introduction carefully. The monohybrid cross tutorials (click on problems 11 & 13 before you move on) are essential reading at this point. Once you have studied this material completely, click on the “ABO markers” button to see the next page. Read the "The Human ABO markers: The A, B, and O alleles tutorial page." If you know your own blood type, write that here __________. (Put AB if you do not know your own.) Click on the “Blood Types/Genotypes” button to continue. Read the “How are blood types related to the six genotypes?” page. What are all of your possible genotypes, based on the blood type you listed above? ______________________________________________________________________________ What are your parent’s possible genotypes?___________________________________________ Click on the “Alleles Inherited” button to continue. Read the “How are ABO alleles inherited by our children?” page carefully. Using the blood type calculator, check to see if you were correct about the blood types of your parents. Now hook up with another person and use the second calculator to see what the possible blood types of your children would be. Write your blood types and your children’s possible types here:__________________________________________________________________________ Now click on the “Rh Factor” button to continue. Carefully study the page “What about the Rh factor?” then click on the “Blood Types Problem Set” to test what you’ve learned. Once there, click on the “Begin Problem Set” to test your group. There are only six problems, so be careful! Be sure to read the explanations both when you are right and when you are wrong… Record your score here: _____correct out of six. Who’s yer daddy? Physiology: Blood Web Quest Click on the link below to begin learning about the blood and follow the instructions below. http://www.pbs.org/wnet/redgold/history/timeline3.html Directions: Please note that you now have 2 WINDOWS OPEN. If you look at the bottom of your computer, you will see that you can still access my web page by clicking on the minimized window. Read through the web page very carefully. If you need to, you may print out the text and read it that way or just re-read as often as necessary. 1) What year was the first modern human to human blood transfusion performed?_________________ 2)What year were platelets discovered? ______________ 3) By whom?_______________________ 4) What scientist was able to perform the first transfusion using crossmatching, and over the next several years successfully used the procedure in 128 cases?_______________________________________ 5) In what year was the first blood depot established and why was it established?_________________ ______________________________________________________________________________ ______________________________________________________________________________ Next, click on this link to learn all about the blood groups: http://www.pbs.org/wnet/redgold/basics/bloodgroups.html ABO blood groups are defined by specific, inherited molecules known as 6) ______________________ that are found oon the surface of 7) ____________ blood cells. A person has a natural immunity or antibody to protect themselves from other blood types. 8) What antibody(ies) does a person with blood type O have?_________________________________ 9-10) List the most common blood types in the United States. _______ and _______. 11) In the U.S., what is the percentage of peoople with type AB-?_________________________. Go to the following web site on blood types by typing in this address: http://anthro.palomar.edu/blood/ABO_system.htm Directions: Read through the web page very carefully. If you need to, you may print out the text and read it that way or just re-read as often as necessary. 12) Who is the scientist that is reputed as being the first to discover blood types? ____________________________________ 13) What year did he die?__________ 14-15)What are the four types of blood found in primates? ________, _________, _________, and _________ Complete the chart: ABO antigen blood group A A yes B no AB antigen antibody antibody B anti-A anti-B no no yes yes 16-17) If a person has Type B blood, what antigens and antibodies are present in their blood? antigen(s) _________________ antibody(ies) _________________________ 18-19) If a person has Type AB blood, what antigens and antibodies are present in their blood? antigen(s) _________________ antibody(ies) _________________________ Analyzing Genetic Inheritance Patterns: 20) According to the genetic inheritance chart, can a person who is Type O blood, have a parent with type A blood? _____________ Explain why or why not? _______________________________ _________________________________________________________________________
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