From: β-Catenin Activation and Epithelial-Mesenchymal Transition in the Pathogenesis of Pterygium
Invest. Ophthalmol. Vis. Sci.. 2007;48(4):1511-1517. doi:10.1167/iovs.06-1060
Figure Legend:
Transmission electron micrographs of pterygial epithelium. (A) PECs slightly posterior to the pterygial head are small,
cuboid basal cells with high cytoplasmic electron density resembling normal basal limbal epithelial cells. The basal
cytoplasmic membrane shows indentations associated with the basement membrane (arrowheads). (B) High
magnification of basal PECs. Numerous fibrils are observed in the cytoplasm. A multilayered basement membrane
(arrowheads) is observed intermingled with irregular extracellular collagen fibers in the stromal fibrous tissue (FT). (C)
Leading head of an epithelial indentation extending into the underlying stroma. PECs with high cytoplasmic electron
density
are shown
with enlarged intercellular
spaces.
stromaand
contains
enlarged,
fusiform©fibroblast-like
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(Fb). (D) Adjacent section of (C). PECs no longer have intercellular adhesion complexes, and show enlarged intercellular