Stages in crown development. A. Dental lamina stage. Localized bands of proliferating cells in the basal layer of the stratified oral epithelium, peripheral to the developing tongue, form two (one per jaw) horseshoe-shaped epithelial ridges, or dental laminae, over the mesenchyme of the future mandibular and maxillary arches. B. Bud stage. Stimulated by local clusters of neural crest–derived mesenchyme cells, proliferation increases in the base of each dental lamina at the 10 sites of future deciduous teeth. These epithelial tooth buds enlarge and bulge into the underlying mesenchyme. C. Early cap stage. With further proliferation, the deep bud surfaces invaginate and widen to form solid caps over mesenchymal clusters. In the cap's core, the cell density decreases as internal cells become stellate and the interstices accumulate tissue fluid. The peripheral cells, which contact the basal lamina, form a simple Source: Chapter 15. Digestive Tract, Histology & Cell Biology: Examination & Board Review, 5e epithelial shell and continue to divide, increasing the cap's size. A stalk of dental lamina connects each cap to the oral epithelium. The mesenchyme under Citation:and Paulsen DF. Histology & Cell Examination Board Review, 5e; 2010within Available http://mhmedical.com/ Accessed: 31, the cap proliferates condenses, indenting the Biology: cap's base. D. Late & cap stage. Mesenchyme the at: indentation forms the dental papilla,July further 2017 indenting the cap's base. The epithelial cells over the papilla (inner enamel epithelium) become columnar, whereas those forming the rest of the shell Copyright © 2017 McGraw-Hill Education. All rights (outer enamel epithelium) remain low cuboidal. The stellate cellsreserved and fluid inside the shell make up the stellate reticulum. Between the stellate reticulum and the inner enamel epithelium lies a layer of epithelial cells called the stratum intermedium. Together, the inner and outer epithelia, stratum intermedium,
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