UVB Exposure Prevents Atherosclerosis by Regulating
Immunoinflammatory ResponsesHighlights
by Naoto Sasaki, Tomoya Yamashita, Kazuyuki Kasahara, Atsushi Fukunaga,
Tomoyuki Yamaguchi, Takuo Emoto, Keiko Yodoi, Takuya Matsumoto, Kenji
Nakajima, Tomoyuki Kita, Masafumi Takeda, Taiji Mizoguchi, Tomohiro Hayashi,
Yoshihiro Sasaki, Mayumi Hatakeyama, Kumiko Taguchi, Ken Washio, Shimon
Sakaguchi, Bernard Malissen, Chikako Nishigori, and Ken-ichi Hirata
Arterioscler Thromb Vasc Biol
Volume 37(1):66-74
December 21, 2016
Copyright © American Heart Association, Inc. All rights reserved.
Naoto Sasaki et al. Arterioscler Thromb Vasc Biol.
2017;37:66-74
Copyright © American Heart Association, Inc. All rights reserved.
UVB irradiation inhibits the development of atherosclerosis and plaque inflammation.
Naoto Sasaki et al. Arterioscler Thromb Vasc Biol.
2017;37:66-74
Copyright © American Heart Association, Inc. All rights reserved.
UVB irradiation expands CD4+ forkhead box P3 (Foxp3)+ regulatory T cells (Tregs) with potent
suppressive activity and suppresses proatherogenic T-cell responses.
Naoto Sasaki et al. Arterioscler Thromb Vasc Biol.
2017;37:66-74
Copyright © American Heart Association, Inc. All rights reserved.
Epidermal Langerhans cells (LCs) are critically involved in UVB-dependent induction of CD4+
forkhead box P3 (Foxp3)+ regulatory T cells (Tregs) and suppression of proatherogenic T-cell
responses.
Naoto Sasaki et al. Arterioscler Thromb Vasc Biol.
2017;37:66-74
Copyright © American Heart Association, Inc. All rights reserved.
Epidermal Langerhans cells (LCs) play an indispensable role in UVB-dependent reduction of
atherosclerosis development and plaque inflammation.
Naoto Sasaki et al. Arterioscler Thromb Vasc Biol.
2017;37:66-74
Copyright © American Heart Association, Inc. All rights reserved.