Table 1. Revision of studies analyzing immunotoxicity of cultivated wheats of different level of ploidy: number
of genotypes included in the study, type of protein and detection method.
Species
Number of accessions Protein
Detection method Reference
T. monococcum
15
Alpha and gamma gliadins
T-cell
(54)
T. monococcum
2
Alpha and gamma gliadins
HMW and LMW glutenins
mAbs
IFN-γ
T-cell
(51)
T. monococcum
1
Alpha gliadins
Epitope screening
(69)
T. monococcum
1
NS (a)
IFN-γ
(70)
T. monococcum
1
All
(b)
Epitope screening
(71)
T. monococcum
3
Alpha gliadins
Epitope screening
mAbs
IFN-γ
(72)
T. monococcum
1
Gamma gliadins
Epitope screening
T-cell
(73)
T. monococcum
2
NS
IFN-γ
T-cell
IL-15
(74)
T. monococcum
1
NS
T-cell
(75)
T. durum
10
Alpha and gamma gliadins
T-cell
(54)
T. durum
4
NS
T-cell
(75)
T. durum
6
Alpha gliadins
mAbs
(76)
T. durum
7
Alpha gliadins
Epitope screening
(77)
T. durum
51
Alpha gliadins
mAbs
(52)
T. aestivum
1
Alpha and gamma gliadins
T-cell
(54)
T. aestivum
5
Alpha and gamma gliadins
HMW and LMW glutenins
mAbs
IFN-γ
T-cell
(51)
T. aestivum
1
NS
T-cell
(75)
T. aestivum
8
Alpha gliadins
Epitope screening
(77)
T. aestivum
2
Alpha gliadins
Epitope screening
(78)
T. aestivum
3
Alpha gliadins
mAbs
(52)
T. aestivum
86
Alpha and gamma gliadins
HMW and LMW glutenins
mAbs
(53)
T. aestivum
2
NS
IFN-γ
anti-tTG
(79)
(a) Not specified
(b) All prolamin fractions