KING ABDULAZIZ UNIVERSITY FACULTY OF SCIENCE GIRLS’S SECTION Course Syllabus COURSE DETAILS SEMESTER 2ed Semester 2015 DEPARTMENT BIOCHEMISTRY COURSE CODE BIOC 371 COURSE TITLE GENERAL BIOCHEMISTRY NUMBER OF CONTACT HOURS CLASS TIME 4 HOURS (11-12) SUNDAY, TUESDAY,THURSDAY FAR & FBR SECTIONS CLASSROOM 72 C COURSE INSTRUCTOR DETAILS INSTRUCTOR NAME OFFICE NUMBER OFFICE HOURS WEBSITE E-MAIL Dr. ULFAT M OMAR 2-114 SUNDAY, TUESDAY and THURSDAY (12-2) http://uomer.kau.edu.sa [email protected] 1 I. COURSE DESCRIPTION: This course introduces the principles of biochemistry such as: 1. General introduction about organic and inorganic chemistry 2. General introduction about acids, bases, buffers, pH and solutions 3. General introduction about the prokaryotic and eukaryotic cells structure 4. Amino acids and proteins [characteristics, classifications, functions, digestion and metabolism] 5. Major proteins families [enzymes, vitamins, hormones, and antibodies] 6. Saccharides and carbohydrates [characteristics, classifications, functions, digestion and metabolism] 7. Fatty acids and lipids [characteristics, classifications, functions, digestion and metabolism] 8. Cell membranes structure and lipoproteins [biological importance] 9. Nucleic acids [characteristics, classifications, functions, digestion and metabolism]. II. COURSE PREREQUESITS N/A III. COURSE OBJECTIVES: By the end of this course, students will be able to: 1. Recognize the major types of chemical bonds. 2. Describe the concepts of pH, buffers and the difference between acids and bases. 3. Identify and characterize carbohydrates, lipids, amino acids, and nucleic acids. 4. Recognize the structures and functions of major biomolecules in living system. 5. Classify enzymes and explain the terminology used with them. 6. Recognize general functions of hormones. 7. Identify the types of vitamins and their importance to human body 8. Develop familiarity with biochemical laboratory instrumentations and techniques. IV. COURSE TOPICS: Chapter 1: The chemistry of life What is biochemistry? Isotopes and compounds Chemical bonds Solutions Acids and bases Water Chapter 2: Carbohydrates Overview of carbohydrates Classification of carbohydrates Monosaccharides Disaccharides Oligosaccharides Polysaccharides 2 Digestion, absorption, and metabolism of carbohydrates Diseases related to abnormal carbohydrate metabolism Chapter 3: Proteins Prokaryotes and eukaryotes Proteins types Amino acids overview Amino acids classification Abbreviation and symbols of amino acids Optical properties of amino acids Zwitterions and isoelectric point (pI) Protein solubility Protein structure Denaturation of proteins Examples of major protein families (enzymes, antibodies, and hormones) Digestion, absorption and metabolism of proteins Chapter 4: Lipids Overview of lipids Classification of lipids Simple lipids Complex lipids Derived lipids Digestion, absorption and metabolism of lipids Chapter 5: Nucleic acids Overview of the nucleic acids Nucleotides and nucleosides Functions of nucleotides DNA structure DNA replication RNA overview Protein synthesis Gene mutations Chromosomal mutations Nucleotides anabolism and catabolism V. LAB COMPONENTS: Please ask your lab instructor for more details about the lab work. VI. TEACHING LEARNING STRATEGIES: To do well, students should attend class and take very detailed notes. You should rely on your lecture notes rather than the text as your primary study resource. You will be responsible for everything covered in lecture, but not responsible for material that is covered in the text but not in lecture. It is not possible to cover all the topics in the text. To get most out of the lectures, it is recommended you read the text before lecture, and then reread the text in more detail after the lecture to make sure you understand all concepts. The lectures move quite rapidly, so 3 reading the text before lecture will improve your comprehension. Always go over your lecture notes within a day of the lecture. VII. POLICIES: Attendance & Tardiness: Any student-missing class/classes will be counted absent and her absence will fall within the 25% absence range. It is the student’s responsibility to make sure she is not missing any exam, quizzes or any other course class assignments. All students are responsible for work missed during their absence. The course instructor is NOT obliged to repeat her lecture or coursework missed by the student due to her absence. Students are expected to meet the following Be punctual in coming to class. You will be marked absent if you enter the class after 10 minutes of starting time. Absenteeism for more than 25% of allocated course lectures, will entitle the instructor to stop you from attending the final exam. You will receive an F grade. Turn off mobile telephones during classes. If a mobile rings during class, it will be taken from the student and returned only at the end of the semester. Do not leave the classroom except in case of emergency and when the instructor gives you the permission to do so. There might be a quiz after each chapter (topic) is finished (optional). These quizzes will not be repeated. Any late/missed assignments will not be accepted after the due date, automatically resulting in a zero. Food and drink are not allowed in the class. VIII. COURSE EVALUATION/GRADING: Indicator Periodical exam 1 Midterm exam Periodical exam 2 Lab Final exam Total IX. Points 10 20 10 25 35 100 GRADING SCALE: 95-100 90-94 85-89 80-84 75-79 70-74 65-69 60-64 60 = A+ =A = B+ = B = C+ = C = D+ = D =F 4 X. TEXTS & MATERIALS Murray, R., Bender, D., Botham, K., Kennelly, P., Rodwell, V., Weil., P. (2012) Harper’s illustrated biochemistry, 29th edition. Publisher: McGraw Hill Lange. Nelson, D. and Cox, M. (2008) Lehninger principles of biochemistry, 5th edition. Publisher: W.H. Freeman and company, New York. Bettelheim, F. (2007). Introduction to general, organic, and Biochemistry (8th ed.). Belmont, Thomson Brooks/Cole. ISBN-13: 978-0-495-01197-2. Biochemistry online by henry Jacubowski http://employees.csbsju.edu/hjakubowski/classes/ch331/bcintro/default.html 5 XI.COURSE PLAN: Week Date 1 5-9/4/1436 2 12-16/4/1436 3 19-23/4/1436 4 26-30-/4/1436 5 3-7/5/1436 6 10-14/5/1436 Subject/Topic References Introduction to Biomolecules Chemical bonds Properties of Water Acids and Bases: Properties and some reactions Acids and Bases: PH, POH, buffers, acidosis and alkalosis Carbohydrates: Monosaccharides and disaccharides Chapter 4 Chapter 7 Exams Syllabus Oligosaccharides and Polysaccharides Chapter 9 Chapter 9 Chapter 20 Chapter 20 7 17-21/5/1436 Lipids: Structure and properties 8 24-28/5/1436 Chapter 21 9 9-13/6/1436 Lipid Classification Biological membranes and lipoproteins Midterm Break 29/5-8/6/ 1436 Amino acids 10 16-20/6/1436 Proteins Chapter 22 11 23-27/6/1436 Chapter 25 12 30/6-4/7/1436 13 7- 11/7/1436 14 14-18/7/1436 Nucleotides, nucleic acids and heredity Gene expression and protein synthesis Introduction to Enzymes and Hormones Vitamins 15 21-25/7/1436 Revision Test 1 Thursday 7/5/1435 Chapter 21 Chapter 22 Midterm Exam Thursday 20/6/1436 Chapter 26 Chapter 23 & 24 Chapter 30 Test 2 Thursday 11/7/1436 Final Lab exams Final exams 28/7- 17/8/1436 6
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