DCP Faculty for the Psychology Of Older People www.psige.org Division of Clinical Psychology ‘Promoting Psychological Wellbeing in Later Life’ Letter to all members of the Faculty of the Psychology of Older People Dear Colleagues, We have received a number of requests for information in the about whether it is possible for psychologists working with older people to use the Mini Mental State Examination (MMSE) now that the copyright is held by PAR. In addition, we have been asked whether tools that include the MMSE (such as the Addenbrookes Cognitive Examination Scale – Revised: ACE-R) are available for use. The national committee has not made a clear statement until now because of the complexity of the issues involved. We would now like to make the following points. The Mini Mental State Examination and its variants The Mini Mental State Examination (MMSE) and the Standardised Mini Mental State Examination (SMMSE) are widely used in clinical settings, and in particular by Memory Clinics in relation to the issue of prescribing cholinesterase inhibitors (as indicated in NICE guidance). The ACE-R is a more detailed screening assessment that incorporates the MMSE. The copyright and use of these instruments is as follows: MMSE – Copyright held by PAR. This tool is available for use, but copies of the tool must be bought from PAR (see www.parinc.com for more details) SMMSE – Copyright held by D William Molloy and colleagues. The national committee has contacted Dr Molloy and colleagues about use of the SMMSE, and they have indicated that they will grant permission for its use to individual psychologists who apply to them on a test by test basis (see www.smmse.com for more details and the attached document) ACE-R – Copyright held by Professor John Hodges. Professor Hodges has currently withdrawn the ACE-R from the website and it is not freely available. It is our understanding that use of the ACE-R is likely to infringe the PAR copyright because of the inclusion of the MMSE items Therefore, the Faculty’s advice is that the ACE-R cannot be used at present, and people wishing to use the MMSE must buy test forms from PAR. Psychologists still wishing to use the SMMSE should apply individually to Molloy via the website and there is no charge for its use. Alternative screening tests An alternative screening test is the Montreal Cognitive Assessment (MoCA). Copyright for this is held by Dr Z Nasreddine and the test can be used without charge and without permission in clinical settings. There is extensive normative data for the test and it is available in multiple versions and multiple languages (www.mocatest.org). 1 FPOP Guidance re MMSE 31 10 12 Professor Hodges and colleagues have been developing an alternative Addenbrooke’s Cognitive Examination tool in which the MMSE items have been removed. The tool will be called the ACE-III or ACE-S will be re-piloted and re-normed. Once this has been completed, Prof Hodges has informed us that it will be made available for clinical use without charge. It was released the last week of October 2012. Please see link below. http://www.neura.edu.au/frontier/research/test-downloads/ More detailed assessment Psychologists are encouraged to consider when it is appropriate to use screening tests versus more detailed neuropsychological testing. The following matrix has been developed by Dr Donald Brechin and Professor Jon Evans as a guide to assist with this: Cognitive deficit found on screening(e.g. MoCA/ACE) Functional impairment found from clinical history Cognitive screening scores and clinical history consistent with each other Presentation fits a recognised profile - - Action Specialist to make diagnosis Consider further neuropsychological assessment before diagnosis Note: The above table focuses on the criteria for considering specialist neuropsychological testing. Other diagnostic tests (e.g. neuroimaging) may be required to make a diagnosis. Psychologists should carefully consider which aspects of function they are assessing and why, and identify a suitably reliable and well normed neuropsychological test that is suitable for this purpose. If they require more information and support in this matter they should seek it from their psychologist with extensive experience of administering neuropsychological assessments with older people. The Table below is an extract from the Neuropsychological Test Inventory about the SMMSE collated by Tamsin Fryer for further information. Yours faithfully Cath Burley DCP Chair Faculty of the Psychology of Older People Don Brechin Former Chair Faculty of the Psychology of Older People 2 FPOP Guidance re MMSE 31 10 12 Appendix Test Name What it measures? Description Suitable groups for assessment Format/materials Scoring Duration Normative Data, reliability and validity Standardised Mini Mental State Examination The Standardised MMSE (Molloy, Alemayehu, Roberts, 1991) is an attempt to address some of the limitations of the MMSE as administration and scoring in clinical practice is variable. The MMSE is probably the most widely used cognitive screening instrument. It intends to identify people with a moderate to severe level of cognitive impairment. It lacks the sensitivity to discriminate between people with mild Alzheimer’s disease from those without and is not sufficiently sensitive to detect some of the more fronto-temporal presentations of dementia. It is the measure relied upon by NICE in relation to guidance for the prescription and monitoring of anti-cholinesterase inhibitors. Test items include attention/orientation, memory (short recall of 3 words), visuospatial (construction), and language (writing, reading, naming, and repetition). Age range: 18-85+ Scores affected by educational level, socio and cultural factors, visual impairment and aphasia. Ceiling effects for people with above average natural ability. Floor effects for those with mild learning disabilities. Probably not sensitive enough to detect MCI. Manual includes some useful information on interpretation of scores. Hand scored and no special equipment needed. The SMMSE is available online in various formats (see below). Full guidance for standardised scoring provided in the 1991 journal article and the manual. 30-26 Could be normal 25-20 Mild 19-10 Moderate 9-0 Severe 10 minutes. Normative data is available from a number of different studies, the largest of which appears to be Crum et al (1993)’s sample of 18,000 community dwelling adults aged 18-85. The Molloy et al (1991) study suggested that by following their standardised administration, the interrater variance was reduced by 76% and the intrarater variance by 86%. Traditional MMSE has been translated into over 100 languages, but these have not been sufficiently validated (Auer et al, 2000). Modest to high correlations demonstrated when the MMSE was compared with the DRS, Information-Memory-Concentration Test, Clock Drawing Task, Mental Status Questionnaire (Spanish Version), Blessed Test. MMSE scores correlate modestly with ADL performance. If the SMMSE is being used to monitor change, small changes must be interpreted judiciously. Iverson (1998) suggests a change of 2 points or more might be statistically reliable, dependent upon age and education whilst Clark et al (1999) recommend a meaningful change would be reflected in a change of 3 or more points and Doody et al (2001) suggests this would need to be more than 5. See the following article for a description of standardised procedures for administration: http://www.dementiaassessment.com.au/guidelines/Guide_Standardised_MMSE.pdf Authors (Full reference: Molloy, D. W., Alemayehu, E. & Roberts, R. (1991) Reliability of a standardized Mini-Mental State Examination compared with the traditional MiniMental State Examination. American Journal of Psychiatry, 148, 102-105.) 3 FPOP Guidance re MMSE 31 10 12 Source & Costs The assessment is embedded in this table, but permission must be sought from the author (Dr. Will Molloy) to use it: SMMSE users guide SMMSE form SMMSE form with instructions Online version: http://smmse.com/ucc/ui/smmse/home App available at : http://itunes.apple.com/gb/app/smmse/id517599997?mt=8 The traditional MMSE, as copyrighted by PAR Inc can be sourced at: http://www4.parinc.com/Products/Product.aspx?ProductID=MMSE#Relate dProducts Full reference to the original paper: Folstein, M. F.; Folstein, S. E. & Additional Information Relevant links: McHugh, P. R. 1975. ''MMS'. A practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research, 12, 189-198. Vertesi A, Lever JA, Molloy DW, et al. 2001. Standardized mini-mental state examination: Use and interpretation. Canadian Family Physician;47:2 018-2023. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2018449/pdf/11723596.p df http://ajp.psychiatryonline.org/article.aspx?volume=148&page=102 4 FPOP Guidance re MMSE 31 10 12
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