Chapter 7 Guided Notes Phospholipid Bilayer- __________________________ head, hydro____________ ___________________________ tails, hydro___________ The bilayer serves as a cellular barrier or border: heads are polar/ nonpolar & tails are polar/ nonpolar Impermeable to _______________ molecules The cell membrane is a thin barrier about ________ thick. ** Which substances can cross more easily than others? Hydrophobic (nonpolar) or Hydrophilic polar? Phospholipid bilayer becomes semi-permeable due to _________________ __________________ that allow specific material across the cell membrane The cell membrane is more than lipids! ** Which are proteins the perfect molecule to build structures in the cell membrane? Within membrane: _______________________ amino acids, hydro________________ Anchors protein into membrane On outer surface of membrane in fluid: ____________________ amino acids, hydro____________ extend into extracellular fluid and into cytosol ** What is an aquaporin? Function through __________________________________ change – protein changes shape Many functions of membrane proteins- 6 examples 1. 2. 3. 4. 5. 6. Proteins determine membrane’s specific functions - unique collections of proteins Classes of membrane proteins _________________________________ proteins, loosely bound to surface of membrane ex: ________________________________ proteins, penetrate lipid bilayer, usually across whole membrane. Transmembrane protein. Ex: Chapter 7 Guided Notes In 1972, _____________________________ & ____________________________ proposed that membrane proteins are inserted into the phospholipid bilayer. The _______________________________ ______________________________ Model ** What other molecules are embedded in the fluid matrix of the lipid bilayer? Membrane Carbohydrates- play a key role in ________________________________________________ Distinguish one cell from another. Ex: Important in & Basis for MOVEMENT ACROSS THE CELL MEMBRANE Diffusion- movement from ____________________________ transport, no energy needed Diffusion through protein channels called ____________________________________________ Active transport- cells may need to move moelcules ___________________ the concentration gradient. _________________________________________________________ transport solute from one side of membrane to other. Ex: Cost: ** Anitport vs. Symport How about large molecules? Movement into or out of the cell through ________________________ & ______________________ Endocytosis – __________________________ = cellular eating ___________________________ = cellular drinking Exoctosis – Concentration of water – direction of osmosis is determined by comparing total solute concentrations Hyptertonic – HypotonicIsotonicHypotonic – a cell in fresh water – high concetration of water around the cell Problem: Example: Solution: Plant cells - Chapter 7 Guided Notes Hypertonic- a cell in salt water- low concentration of water around the cell Problem: Example: Solution: Plant cellsIsotonic- animal cell immersed in mild salt solution. No difference in concentration of water between cell and environment Problem: Example: AquaporinsEvidence that there were water channels, protein channels allowing flow of water across cell membrane. Cell (compared to beaker) Beaker (compared to cell) Which way does the water flow? Diffusion through phospholipid bilayer What molecules can get through directly? What molecules can NOT get through directly? Membrane fat composition varies- Fat composition affects flexibility _______________________ - unsaturated hydrocarbon tails with kinks ________________________ - saturated hydrocarbon tails
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