actin
actin
troponin
tropomyosin
actin
troponin
tropomyosin
actin
troponin
myosin binding site
tropomyosin
actin
troponin
Ca2+
Ca2+
Ca2+
Ca2+
Ca2+
Ca2+
Ca2+
Ca2+
Calcium ions are released from the sarcolemma after
stimulation from the T system
Ca2+
Ca2+
Ca2+
Ca2+
Ca2+
Ca2+
Ca2+
Ca2+
the calcium ions bind to the troponin and changes its shape
Ca2+
Ca2+
Ca2+
Ca2+
the calcium ions bind to the troponin and changes its shape
Ca2+
Ca2+
Ca2+
Ca2+
Ca2+
Ca2+
Ca2+
Ca2+
Ca2+
Ca2+
Ca2+
the troponin displaces the tropomyosin and exposes the
myosin binding sites
Ca2+
Ca2+
Ca2+
Ca2+
Ca2+
Ca2+
Ca2+
Ca2+
Ca2+
Ca2+
Ca2+
Ca2+
the bulbous heads of the myosin attach to the binding
sites on the actin filaments
Ca2+
Ca2+
Ca2+
Ca2+
Ca2+
Ca2+
Ca2+
Ca2+
Ca2+
Ca2+
Ca2+
the myosin heads change position to achieve a lower
energy state and slide the actin filaments past the
stationary myosin
Ca2+
Pi Pi Pi A
Ca2+
Ca2+
Pi P i Pi A
Pi Pi Pi A
Pi Pi Pi A
Pi Pi Pi Ca
A 2+
Ca2+
Pi Pi Pi A
Ca2+
Pi Pi Pi A
Pi Pi Pi Ca
A 2+
Ca2+
Pi Pi Pi A
Ca2+
ATP binds to the bulbous heads and causes it to become
detached
Pi Pi Pi A
Pi Pi Pi A
Pi Pi Pi A
Ca2+
Ca2+
Ca2+
ATP binds to the bulbous heads and causes it to become
detached
Pi
Pi Pi A
Pi
Pi
Pi Pi A
Pi Pi A
Ca2+
Ca2+
Ca2+
hydrolysis of ATP provides the energy to “re-cock” the heads
Pi
Pi Pi A
Pi
Pi
Pi Pi A
Pi Pi A
Ca2+
Ca2+
Ca2+
hydrolysis of ATP provides the energy to “re-cock” the heads
Pi
Pi Pi A
Pi
Pi
Pi Pi A
Pi Pi A
Ca2+
Ca2+
Ca2+
Pi
Pi Pi A
Pi
Pi
Pi Pi A
Pi Pi A
Ca2+
Ca2+
Ca2+
calcium ions are re-absorbed back into the T system
Pi
Pi Pi A
Pi
Pi
Pi Pi A
Pi Pi A
calcium ions are re-absorbed back into the T system
Pi
Pi Pi A
Pi
Pi
Pi Pi A
Pi Pi A
the troponin reverts to its normal shape and the tropomyosin
move back to block the myosin binding sites
Pi
Pi Pi A
Pi
Pi
Pi Pi A
Pi Pi A
the troponin reverts to its normal shape and the tropomyosin
move back to block the myosin binding sites
Pi
Pi Pi A
Pi
Pi
Pi Pi A
Pi Pi A
the troponin reverts to its normal shape and the tropomyosin
move back to block the myosin binding sites
Pi
Pi Pi A
Pi
Pi
Pi Pi A
phosphocreatine regenerates ATP
Pi Pi A
Pi
Pi Pi A
Pi
Pi Pi A
phosphocreatine regenerates ATP
Pi Pi Pi A
Pi Pi Pi A
Pi Pi Pi A
phosphocreatine regenerates ATP
Pi Pi Pi A
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