Link between PI3K/AKT/PTEN Pathway and NOX Proteinin Diseases
Atsuko Nakanishi #cod#x00023; ;Yoko Wada;Yasuko Kitagishi;Satoru Matsuda #cod#x00023; ;
Department of Food Science and Nutrition, Nara Women#cod#x02019;s University, Kita-Uoya Nishimachi, Nara 630-8506, Japan ;
Figure 3. Schematic representation of PI3KAKTPTEN signaling, which modulate NOXs-derived ROS. NOXs sense hypoxia and can help to mediate activation of angiogenic
pathway, while maintaining unregulated cell growth and apoptotic cell death. Examples of molecules known to act on the regulatory pathways are shown. Note that some
critical pathways have been omitted for clarity.
null,null,5(3),203-211. Doi:10.14336/AD.2014.0500203