POSTER SESSION
Monday, April 27, 2015 – 8:15 - 9:30p.m. - Peckham Hall Lobby
1. Stephanie L. Daifuku, Malik H. Al-Afyouni, Benjamin E. R. Snyder, Jared L. Kneebone, and
Michael L. Neidig, Chemistry Department, University of Rochester - Electronic Structure,
In-Situ Formation and Reactivity of Mesitylated Iron-Bisphosphines
2. N. Zumbulyadis, L. Switala, W.J. Ryan, and J.P. Hornak, RIT Magnetic Resonance
Laboratory Low Field EPR in Cultural Heritage Science: the Non-Destructive
Characterization of large Intact Objects and Spin Dynamics at Low Fields
3. Aaron P. Walsh and William D. Jones, Chemistry Department, University of Rochester,
Mechanistic Insights of a Concerted-metalation Deprotonation Reaction with [Cp*RhCl2]2
4. James G. Koch*†, Bradley M. Kraft†, William W. Brennessel‡, St. John Fisher College†,
University of Rochester‡ - Synthesis and Characterization of Monoalkylated
Organosilicon Complexes of 1-Hydroxy-2-Pyridinone
5. Banu Kandemir, Jesse G. Kleingardner, Benjamin Dick, and Kara L. Bren, Chemistry
Department, University of Rochester - Hydrogen Evolution from Neutral Water Catalyzed
by Cobalt Biosynthetic Catalysts
6. R. N. Carter1, T. R. Gaborski1, J. J. Miller2, and J. Rousse2, 1. Department of Chemical &
Biomedical Engineering, Rochester Institute of Technology ; 2. SiMPore Inc., W. Henrietta,
NY Feasibility of Large Area Nanoporous Silicon Nitride Membranes for Hemodialysis
ABSTRACT. This project concerns the development of a scale up fabrication technique for a nanoporous
silicon nitride membrane technology that is being developed for application as a high performance membrane to
enable portable hemodialysis. The fabrication technique is based on supporting the ultrathin (ca. 50 nm)
membrane with a polymeric scaffold and then using a through-pore etch to separate the membrane from the
silicon wafer substrate. This technique is termed “lift-off” and builds on recent success in our group involving
similar thickness silicon nitride membranes with micropores that are used as optically transparent porous
substrates for cell culture studies. Presently, the nanoporous membranes are fabricated with method that
produces small active area membrane devices that are supported on rigid silicon chips through an expensive and
time-consuming through-wafer etch. In contrast, the lift-off method yields radically higher active area
membranes with a more flexible form factor while dramatically reducing production costs by eliminating the
expensive through-wafer etch step. In extending this method to the nanoporous membrane we are addressing a
number of anticipated challenges including optimization of the through-pore etch with pores that are
approximately 100-fold smaller and developing a mechanical support scaffold with the appropriate properties for
integration of the membrane technology into hemodialysis devices for laboratory animal studies.
7. Adam M. Feinberg and Joseph P. Dinnocenzo, Department of Chemistry, University of
Rochester - Alkoxyl Radicals as Hydrogen Atom Donors
ABSTRACT Recent experiments and calculations for the photoinduced reductive fragmentation of
N-hydrogen atom
transfer from primary alkoxyl radicals and to pyridine-derived bases, forming the corresponding aldehydes and
N-hydropyridinyl radicals.† More recent nanosecond transient absorption spectroscopy experiments provide
direct support for this unusual and rapid hydrogen atom transfer reaction. For example, the reaction of ethoxyl
radical with 2,6-lutidine proceeds by second-order kinetics with rate constant of 3.5 x 107 M-1 s-1 at 22 °C. The
reaction shows a significant primary isotope effect (kH/kD = 3). Methods for generation and observation of
ethoxyl radicals, as well as the hydrogen atom transfer products, will be discussed, along with the mechanistic
implications of the findings.
†
Shukla, D.; Adiga, S.; Ahearn, W.; Dinnocenzo, J.; Farid, S. J. Org. Chem. 2013, 78, 1955-1964.
8. Henry J. Gysling and Mark Lelental, CatAssays, Rochester, NY - A Unique HighSensitivity Bioassay Incorporating a Heterogeneously Catalyzed Redox Amplification
Reaction
ABSTRACT CatAssays’ proprietary bioassay technology (1-2) is a chemistry-based modification of the
standard ELISA format bioassay. It uses a different labeling reagent for the specific detection antibody (i.e.,
palladium nanoparticle catalyst vs. organic enzyme), and a proprietary palladium-catalyzed dye signalgeneration chemistry compared to the conventional enzyme-based ELISA assay technology which uses a
hydrogen peroxide oxidation of a substrate such as o-phenylenediamine to give a dye signal. In addition to
enhanced sensitivity the other key feature of this technology is its compatibility with the standard ELISA format
assay widely used in the medical diagnostic market, without the need for any capital laboratory investment for
implementation (i.e., its implementation requires changes in the above 2 chemical steps but the dye signal is
detected using the same optical spectrophotometry for dye signal quantification as in standard ELISA
technology).
1. U.S. 7,820,394 (2010): Mark Lelental and Henry J. Gysling, Ultrasensitive Bioanalytical Assay Based on the Use of High-Gain
Catalytic Chemical Amplification
2. U.S. Patent Application 2015/0050672 A1 (Feb. 19, 2015): Mark Lelental and Henry J. Gysling, Catalytic Marking Nanoparticles
for Ultrasensitive Bioassay Applications