Supplemental Figure 1. Mitochondrial extraction. A. Silverstained gradient gel NuPAGE(4-12%). 35 µg of mitochondrial and total lysate protein were loaded. B. Western
blots confirming isolation of mitochondrial proteins (TRAP1, heat shock protein; ATP5A,
ATP synthase subunit alpha) and absence of cytoplasm (GAPDH, glyceraldehyde-3phosphate dehydrogenase; MYG, myoglobin) and nuclear (MYOG, myogenin) proteins. M.
Mitochondrial fraction. D. Discarded fraction. TL. Total lysate.
Supplemental Figure 2. Lactate and pyruvate concentrations were measured in hearts from
mice perfused for 120 with modified Krebs solution without and with UK5099 (n=3/group).
HW. Heart weight. * indicates p-value<0.05
Supplemental Table I. Characteristics of pigs used in present study.
Body weight (kg)
Heart weight (g)
Infarcted area (mm2)
Ctrl-1
27
129
0
Ctrl-2
28
150
0
Ctrl-3
27
129
0
Ctrl-4
30
159
0
Ctrl-5
25
110
0
Ctrl-6
19
90
0
26.0±3.8
127.8±25.3
0.0±0.0
I/R 3-1
20
97
300
I/R 3-2
22
90
875
I/R 3-3
21
75
700
I/R 3-4
19
96
375
I/R 3-5
24
117
375
21.2±1.9
95.0±15.1
525.0±249.4
I/R 15-1
31
189
200
I/R 15-2
31
135
270
I/R 15-3
33
181
500
I/R 15-4
23
117
1050
I/R 15-5
21
150
750
I/R 15-6
20
90
1600
24.9±5.3
133.6±35.7
1068.9±706.5
Pig
Media Ctrl
Media 3 I/R
Media 15 I/R
Supplemental Table II. Total mitochondrial proteins identified
Identified Proteins (442)
Uniprot
accession ID
Molecular
Weight
Total
unique
peptides
Total
unique
spectra
Max. %
coverage
Assigned spectra
Total
Average
Control
Average
3 I/R
Average
15 I/R
14-3-3 protein epsilon
1433E_HUMAN
29 kDa
220
220
62.4%
326
37.7 ± 15.0
45.8 ± 4.4
50.0 ± 13.0
Serine/threonine-protein phosphatase 2A 65
kDa regulatory subunit A alpha isoform
2AAA_HUMAN
65 kDa
30
30
14.4%
114
5.5 ± 4.8
8.8 ± 6.9
6.2 ± 3.1
3-hydroxyisobutyrate dehydrogenase,
mitochondrial
3HIDH_HUMAN
35 kDa
24
24
13.7%
88
4.0 ± 3.3
4.2 ± 5.8
1.5 ± 3.7
Uncharacterized protein A0A075B7H9
A0A075B7H9_PIG
12 kDa
71
71
40.2%
12
9.5 ± 4.8
14.6 ± 9.3
14.0 ± 2.8
Mitochondrial NDUFA4
A1XQS3_PIG
9 kDa
145
145
96.3%
760
55.2 ± 10.5
51.6 ± 7.2
46.5 ± 8.9
COX8H
A1XQT4_PIG
8 kDa
4
4
31.4%
2
0.0 ± 0.0
0.4 ± 0.9
0.3 ± 0.8
Estradiol 17-beta-dehydrogenase 8
A5D9P1_PIG
27 kDa
40
40
28.6%
27
1.0 ± 1.7
4.0 ± 1.7
3.3 ± 2.2
ATP synthase, H+ transporting, mitochondrial
F1 complex, epsilon subunit
A5GFX4_PIG
6 kDa
23
23
41.2%
290
5.5 ± 3.3
4.8 ± 4.8
1.8 ± 2.9
Aspartate aminotransferase, mitochondrial
AATM_PIG
47 kDa
411
411
76.5%
797
108.5 ± 29.6
152.2 ± 15.4
127.5 ± 16.3
Long-chain specific acyl-CoA dehydrogenase,
mitochondrial
ACADL_PIG
48 kDa
294
294
46.3%
403
58.5 ± 16.1
87.8 ± 11.2
64.3 ± 9.8
Medium-chain specific acyl-CoA
dehydrogenase, mitochondrial
ACADM_PIG
46 kDa
298
298
53.0%
880
46.7 ± 14.5
59.2 ± 12.9
56.2 ± 14.9
Acyl-CoA-binding protein
ACBP_PIG
10 kDa
273
273
44.8%
19
0.5 ± 1.2
2.0 ± 1.4
0.5 ± 1.2
17 kDa
7
7
11.5%
130
0.3 ± 0.8
0.0 ± 0.0
0.0 ± 0.0
Acyl carrier protein, mitochondrial
ACPM_HUMAN
(+1)
ADP/ATP translocase 3
ADT3_PIG
33 kDa
158
158
47.7%
1958
28.0 ± 30.9
66.8 ± 7.9
49.2 ± 24.4
AFG3-like protein 2
AFG32_HUMAN
89 kDa
2
2
3.6%
32
1.3 ± 2.1
2.6 ± 2.5
1.2 ± 1.3
Aldehyde dehydrogenase, mitochondrial
ALDH2_PIG
57 kDa
18
18
5.2%
3
0.0 ± 0.0
0.8 ± 1.8
0.0 ± 0.0
Arginine and glutamate-rich protein 1
ARGL1_HUMAN
33 kDa
78
78
9.9%
65
1.3 ± 1.5
1.2 ± 1.8
1.5 ± 1.6
Actin-related protein 2/3 complex subunit 2
ARPC2_HUMAN
34 kDa
126
126
28.3%
10
3.8 ± 2.2
6.2 ± 3.2
6.2 ± 1.8
ATPase inhibitor, mitochondrial ATPIF1
ATIF1_PIG
12 kDa
38
38
43.5%
135
16.2 ± 10.0
9.4 ± 1.1
14.0 ± 7.5
ATP synthase subunit d, mitochondrial
ATP5H_HUMAN
18 kDa
123
123
19.3%
263
4.2 ± 10.2
16.4 ± 15.2
16.0 ± 12.8
ATP synthase subunit e, mitochondrial
ATP5I_PIG
8 kDa
28
28
73.2%
203
61.7 ± 35.0
153.0 ± 24.9
118.5 ± 44.8
ATP synthase-coupling factor 6, mitochondrial
ATP5J
ATP5J_PIG
9 kDa
24
24
75.0%
123
4.0 ± 4.5
9.6 ± 2.2
8.5 ± 6.2
ATP synthase subunit a MT-ATP6
ATP6_PIG
25 kDa
49
49
10.2%
93
3.8 ± 3.1
2.4 ± 5.4
13.2 ± 2.1
ATP synthase protein 8
ATP8_PIG
8 kDa
620
620
59.7%
155
17.7 ± 6.3
15.2 ± 6.0
12.8 ± 6.3
ATP synthase subunit alpha, mitochondrial
ATPA_PIG
60 kDa
867
867
73.1%
18374
909.5 ±
220.1
1231.4 ± 64.7
1126.7 ± 221.7
ATP synthase mitochondrial F1 complex
assembly factor 1
ATPF1_HUMAN
36 kDa
4
4
10.1%
9
0.0 ± 0.0
0.8 ± 1.1
0.0 ± 0.0
ATP synthase subunit gamma, mitochondrial
ATPG_HUMAN
33 kDa
76
76
15.4%
702
28.5 ± 6.4
32.6 ± 4.3
33.3 ± 5.5
ATP synthase subunit f, mitochondrial
ATPK_PIG
10 kDa
54
54
48.9%
314
28.8 ± 5.1
26.8 ± 15.3
19.7 ± 15.5
ATP synthase subunit O, mitochondrial
ATPO_PIG
23 kDa
257
257
81.2%
2570
132.3 ± 44.0
127.6 ± 6.1
129.5 ± 11.3
Methylglutaconyl-CoA hydratase,
mitochondrial
AUHM_HUMAN
36 kDa
55
55
21.8%
0
2.3 ± 1.9
6.6 ± 1.9
2.5 ± 1.8
Cytochrome b reductase 1 CYBRD1
B2ZPK1_PIG
32 kDa
4
4
7.7%
7
1.0 ± 1.5
0.0 ± 0.0
0.0 ± 0.0
D-beta-hydroxybutyrate dehydrogenase,
mitochondrial
BDH_HUMAN
38 kDa
52
52
14.3%
150
14.3 ± 4.0
15.6 ± 2.1
11.2 ± 2.6
Brain protein 44
BR44_HUMAN
?
44
44
0.0%
459
1.7 ± 4.1
17.4 ± 10.0
19.0 ± 7.4
Brain protein 44-like protein
BR44L_HUMAN
?
46
46
0.0%
286
6.3 ± 4.5
12.0 ± 3.8
10.2 ± 3.4
Succinate dehydrogenase cytochrome b560
subunit, mitochondrial
C560_PIG
19 kDa
48
48
21.9%
93
6.0 ± 2.1
11.4 ± 0.9
8.2 ± 5.0
Cathepsin B
CATB_PIG
37 kDa
2
2
8.7%
7
0.5 ± 1.2
0.0 ± 0.0
0.0 ± 0.0
Coiled-coil domain-containing protein 58
CCD58_HUMAN
(+1)
17 kDa
2
2
21.5%
0
0.3 ± 0.8
0.0 ± 0.0
0.0 ± 0.0
10 kDa heat shock protein, mitochondrial
CH10_HUMAN
11 kDa
100
100
80.4%
211
14.3 ± 2.1
27.8 ± 7.7
14.8 ± 8.4
Charged multivesicular body protein 2b
CHM2B_HUMAN
(+1)
24 kDa
29
29
17.0%
40
1.8 ± 2.0
1.6 ± 0.9
2.3 ± 1.4
CDGSH iron-sulfur domain-containing protein
3, mitochondrial
CISD3_HUMAN
14 kDa
48
48
20.5%
13
10.8 ± 3.3
7.6 ± 2.6
5.3 ± 2.7
Citrate synthase, mitochondrial
CISY_PIG
52 kDa
247
247
41.8%
1017
54.8 ± 15.4
74.2 ± 7.7
69.8 ± 5.2
Chloride intracellular channel protein 4
CLIC4_HUMAN
29 kDa
20
20
24.5%
7
0.3 ± 0.8
3.6 ± 3.4
1.8 ± 2.2
Clusterin CLU
CLUS_PIG
52 kDa
53
53
33.0%
41
1.0 ± 1.1
8.0 ± 6.2
3.5 ± 2.7
Calcium-binding mitochondrial carrier protein
Aralar1
CMC1_HUMAN
75 kDa
263
263
36.3%
563
33.3 ± 4.3
39.4 ± 9.7
34.2 ± 8.3
Hexaprenyldihydroxybenzoate
methyltransferase, mitochondrial
COQ3_HUMAN
41 kDa
47
47
11.4%
244
9.3 ± 2.3
12.4 ± 1.8
6.3 ± 2.1
Ubiquinone biosynthesis protein COQ7
homolog
COQ7_HUMAN
24 kDa
41
41
22.1%
80
3.2 ± 1.0
5.4 ± 1.5
2.0 ± 1.7
Cytochrome c oxidase subunit 4 isoform 1,
mitochondrial (Fragment)
COX41_PIG
11 kDa
28
28
62.9%
973
6.5 ± 15.9
17.4 ± 23.8
0.0 ± 0.0
Cytochrome c oxidase subunit 5B,
mitochondrial COX5B
COX5B_PIG
14 kDa
133
133
56.6%
716
36.3 ± 5.7
40.0 ± 9.2
38.8 ± 14.6
Cytochrome c oxidase subunit 7C,
mitochondrial
COX7C_PIG
7 kDa
45
45
31.7%
91
4.2 ± 3.1
5.0 ± 1.2
4.5 ± 2.3
Carnitine O-palmitoyltransferase 1, muscle
isoform
CPT1B_PIG
88 kDa
135
135
20.6%
166
12.7 ± 4.9
18.6 ± 8.3
12.5 ± 5.6
Cytochrome c oxidase subunit 7A1,
mitochondrial
CX7A1_PIG
9 kDa
50
50
31.2%
564
18.5 ± 6.6
16.2 ± 3.1
16.8 ± 3.9
Cytochrome c1, heme protein, mitochondrial
CY1_HUMAN
35 kDa
56
56
23.7%
684
9.8 ± 5.1
17.4 ± 6.7
9.8 ± 5.0
Cytochrome b5 CYB5A
CYB5_PIG
15 kDa
53
53
44.8%
54
4.3 ± 2.9
6.2 ± 2.5
3.7 ± 2.0
Cytochrome c
CYC_PIG
12 kDa
235
235
79.0%
766
36.7 ± 11.3
51.8 ± 8.7
52.3 ± 18.5
Acetyl-Coenzyme A acyltransferase 2
D0G0B3_PIG
42 kDa
305
305
77.1%
1211
57.3 ± 18.4
66.2 ± 19.1
52.5 ± 10.5
Cysteine and glycine-rich protein 3
D2SQP3_PIG
21 kDa
164
164
79.4%
989
61.8 ± 26.6
52.2 ± 10.5
64.2 ± 9.7
N(G),N(G)-dimethylarginine
dimethylaminohydrolase 2
DDAH2_HUMAN
30 kDa
33
33
14.4%
14
1.8 ± 1.5
2.6 ± 1.9
1.8 ± 1.0
ATP-dependent RNA helicase DDX3X
DDX3X_HUMAN
(+1)
73 kDa
51
51
11.5%
3
5.2 ± 2.0
3.2 ± 4.4
5.8 ± 2.4
Dehydrogenase/reductase SDR family
member 4
DHRS4_PIG
30 kDa
186
186
49.1%
868
60.7 ± 15.7
76.0 ± 6.5
77.8 ± 7.2
Dynamin-1-like protein
DNM1L_HUMAN
82 kDa
6
6
4.8%
16
0.3 ± 0.8
1.0 ± 1.4
0.0 ± 0.0
MACRO domain containing protein 1
E7EBY5_PIG
35 kDa
55
55
26.2%
84
6.2 ± 5.1
7.4 ± 1.1
3.5 ± 2.0
Trifunctional enzyme subunit alpha,
mitochondrial
ECHA_PIG
83 kDa
500
500
60.2%
555
124.5 ± 36.2
138.2 ± 32.7
120.2 ± 23.3
Trifunctional enzyme subunit beta,
mitochondrial
ECHB_HUMAN
51 kDa
127
127
64.0%
2545
35.0 ± 27.6
37.2 ± 34.7
26.5 ± 29.4
Elongation factor 1-beta
EF1B_HUMAN (+1)
25 kDa
42
42
24.4%
46
1.5 ± 1.2
4.6 ± 0.9
7.7 ± 2.8
Electron transfer flavoprotein subunit alpha,
mitochondrial
ETFA_HUMAN
35 kDa
16
16
41.4%
1453
8.0 ± 19.6
9.0 ± 20.1
0.0 ± 0.0
Electron transfer flavoprotein subunit beta
ETFB_PIG
28 kDa
237
237
60.0%
126
49.2 ± 9.7
64.6 ± 10.7
48.8 ± 5.3
Uncharacterized protein MTFP1
F1RFC8_PIG
18 kDa
81
81
30.1%
0
9.0 ± 3.0
8.4 ± 3.0
5.0 ± 1.1
Uncharacterized protein USMG5
F1RFD4_PIG
6 kDa
56
56
44.8%
156
15.3 ± 3.0
16.6 ± 2.9
18.5 ± 3.8
Elongation factor Tu
F1RFI1_PIG
49 kDa
251
251
50.0%
835
43.5 ± 12.9
42.6 ± 8.0
35.0 ± 6.3
Uncharacterized protein OMC
F1RFX9_PIG
33 kDa
204
204
54.4%
951
46.2 ± 7.5
60.2 ± 7.5
57.8 ± 13.5
Uncharacterized protein MRPS34
F1RG19_PIG
26 kDa
10
10
10.1%
14
0.8 ± 1.3
0.4 ± 0.9
1.0 ± 1.5
NADH dehydrogenase [ubiquinone] 1 alpha
subcomplex subunit 2
F1RGE3_PIG
11 kDa
124
124
64.6%
654
34.3 ± 5.4
42.4 ± 4.8
29.0 ± 3.5
Stress-70 protein, mitochondrial
F1RGJ3_PIG
74 kDa
358
358
49.8%
1024
46.8 ± 12.1
67.8 ± 16.6
55.2 ± 14.3
Uncharacterized protein COA6
F1RGW3_PIG
15 kDa
2
2
17.6%
2
0.0 ± 0.0
1.4 ± 1.3
0.3 ± 0.8
Uncharacterized protein MRPL24
F1RHJ1_PIG
25 kDa
9
9
11.6%
7
0.0 ± 0.0
1.4 ± 1.3
0.3 ± 0.8
Uncharacterized protein GLOD4
F1RHJ9_PIG
54 kDa
31
31
14.5%
69
1.8 ± 1.6
5.4 ± 2.6
1.0 ± 1.7
Catechol O-methyltransferase
F1RHN3_PIG
30 kDa
21
21
25.6%
26
1.8 ± 1.5
1.4 ± 1.9
1.5 ± 1.8
Uncharacterized protein MRPL16
F1RI89_PIG
29 kDa
5
5
11.6%
24
0.3 ± 0.8
0.6 ± 1.3
0.0 ± 0.0
Uncharacterized protein BCKDK
F1RIR7_PIG
46 kDa
13
13
12.9%
26
3.8 ± 3.2
1.2 ± 2.7
0.7 ± 1.6
Uncharacterized protein (Fragment) MMAB
F1RIS6_PIG
27 kDa
30
30
26.7%
19
3.3 ± 2.7
2.6 ± 1.8
2.2 ± 2.0
Uncharacterized protein CHCHD2
F1RIU9_PIG
16 kDa
27
27
33.3%
50
2.8 ± 2.7
2.4 ± 1.5
2.8 ± 1.5
Uncharacterized protein CBR4
F1RIX8_PIG
25 kDa
55
55
29.0%
88
4.8 ± 2.3
6.8 ± 2.2
5.8 ± 1.0
Uncharacterized protein LOC100525876
F1RJE4_PIG
67 kDa
122
122
20.1%
196
6.3 ± 4.1
12.2 ± 3.3
9.3 ± 2.1
Short-chain-specific acyl-CoA dehydrogenase,
mitochondrial
F1RJH2_PIG
45 kDa
156
156
41.5%
260
21.2 ± 11.5
23.0 ± 5.6
21.7 ± 5.0
Uncharacterized protein (Fragment) ABHD11
F1RJM8_PIG
34 kDa
24
24
12.8%
17
1.3 ± 1.5
3.0 ± 1.0
1.0 ± 1.7
Uncharacterized protein DNAJC30
F1RJN1_PIG
26 kDa
2
2
8.4%
2
0.3 ± 0.8
1.0 ± 1.4
0.0 ± 0.0
Succinyl-CoA ligase subunit beta SUCLA2
F1RK10_PIG
50 kDa
207
207
50.5%
570
30.7 ± 12.0
34.6 ± 5.3
24.0 ± 6.7
Uncharacterized protein TRAP1
F1RK45_PIG
80 kDa
83
83
18.1%
14
3.8 ± 2.5
9.8 ± 2.9
6.2 ± 2.5
Uncharacterized protein (Fragment)
LOC100513918
F1RK50_PIG
14 kDa
58
58
58.1%
61
3.5 ± 1.2
5.6 ± 2.1
4.8 ± 4.0
Uncharacterized protein MRPL40
F1RK59_PIG
24 kDa
43
43
39.3%
83
3.8 ± 3.9
4.8 ± 2.7
2.0 ± 1.1
Succinate dehydrogenase assembly factor 2,
mitochondrial
F1RKQ9_PIG (+1)
20 kDa
2
2
0.0%
4
0.0 ± 0.0
0.4 ± 0.9
0.0 ± 0.0
Isocitrate dehydrogenase [NAD] subunit,
mitochondrial
F1RKU0_PIG
40 kDa
242
242
52.7%
1090
61.3 ± 26.2
78.2 ± 9.4
57.7 ± 9.2
Branched-chain-amino-acid aminotransferase
BCAT2
F1RL80_PIG
45 kDa
48
48
21.4%
81
6.7 ± 5.5
7.0 ± 4.7
2.2 ± 2.6
Uncharacterized protein COX6B
F1RLH7_PIG
10 kDa
199
199
81.4%
11
34.0 ± 7.9
39.4 ± 3.9
40.7 ± 14.3
Uncharacterized protein (Fragment) DAP3
F1RLM4_PIG (+1)
49 kDa
2
2
9.2%
2
0.5 ± 1.2
1.8 ± 1.8
1.0 ± 1.1
Uncharacterized protein (Fragment) TOMM40
F1RM44_PIG (+1)
33 kDa
28
28
16.3%
42
1.7 ± 1.4
1.4 ± 1.3
2.5 ± 0.8
Uncharacterized protein DIABLO
F1RNS2_PIG
27 kDa
53
53
21.1%
77
4.2 ± 1.0
3.6 ± 2.6
5.5 ± 1.8
Cytochrome b-c1 complex subunit Rieske,
mitochondrial
F1RNZ1_PIG
29 kDa
226
226
54.0%
649
59.7 ± 9.6
84.6 ± 14.9
86.0 ± 24.2
Uncharacterized protein F1RP22
F1RP22_PIG
15 kDa
4
4
13.3%
114
0.0 ± 0.0
1.0 ± 1.4
0.0 ± 0.0
Uncharacterized protein (Fragment) CLYBL
F1RP25_PIG
33 kDa
50
50
23.0%
33
2.2 ± 1.8
5.4 ± 0.9
2.5 ± 1.4
NAD(P)H-hydrate epimerase
F1RP34_PIG
31 kDa
2
2
16.0%
2
0.8 ± 1.3
0.0 ± 0.0
0.0 ± 0.0
Uncharacterized protein LOC100620271
F1RPD2_PIG
49 kDa
334
334
53.6%
2626
136.5 ± 29.1
163.6 ± 27.9
192.0 ± 26.6
Uncharacterized protein LOC100620271
F1RPD4_PIG
22 kDa
14
14
44.4%
702
17.7 ± 27.4
0.0 ± 0.0
0.0 ± 0.0
Glycerol-3-phosphate dehydrogenase MGPD
F1RPU0_PIG
81 kDa
8
8
2.3%
59
0.5 ± 1.2
1.8 ± 2.7
0.5 ± 1.2
Uncharacterized protein MPC2
F1RPU8_PIG
14 kDa
69
69
46.1%
290
22.2 ± 5.7
26.6 ± 4.8
20.7 ± 4.2
Uncharacterized protein COX7A2
F1RQI1_PIG
9 kDa
13
13
30.1%
39
0.8 ± 1.3
1.2 ± 1.1
0.5 ± 1.2
Uncharacterized protein PRDX5
F1RQP0_PIG
17 kDa
2
2
14.8%
2
0.3 ± 0.8
0.0 ± 0.0
0.0 ± 0.0
Uncharacterized protein LOC100515705
F1RQS8_PIG
21 kDa
2
2
10.9%
5
0.3 ± 0.8
0.0 ± 0.0
0.0 ± 0.0
Uncharacterized protein MRPL49
F1RQV0_PIG
19 kDa
14
14
30.5%
25
1.0 ± 1.1
2.4 ± 2.3
0.0 ± 0.0
Uncharacterized protein MRPL14
F1RQV7_PIG
16 kDa
14
14
31.0%
28
0.5 ± 1.2
2.0 ± 1.9
1.2 ± 2.0
Uncharacterized protein CRAT
F1RR45_PIG
71 kDa
240
240
39.0%
719
39.3 ± 13.9
45.4 ± 15.9
31.8 ± 6.2
Uncharacterized protein ENDOG
F1RR64_PIG
33 kDa
97
97
41.8%
143
9.3 ± 7.4
9.6 ± 3.0
8.3 ± 3.9
Uncharacterized protein SEPT4
F1RRN6_PIG (+1)
55 kDa
12
12
4.8%
2
0.5 ± 1.2
1.4 ± 1.3
0.8 ± 1.3
Uncharacterized protein TMEM65
F1RRP8_PIG
25 kDa
14
14
14.0%
18
1.3 ± 1.5
1.6 ± 1.7
0.0 ± 0.0
Uncharacterized protein NDUFB9
F1RRP9_PIG (+1)
22 kDa
151
151
73.3%
879
41.3 ± 15.2
40.2 ± 5.4
28.2 ± 6.8
Uncharacterized protein (Fragment) PTGES2
F1RRY6_PIG
43 kDa
106
106
42.1%
27
12.0 ± 6.3
13.0 ± 5.5
14.3 ± 7.8
Uncharacterized protein PTRH1
F1RS13_PIG (+1)
23 kDa
2
2
16.0%
5
0.3 ± 0.8
0.0 ± 0.0
0.0 ± 0.0
78 kDa glucose-regulated protein
F1RS36_PIG (+1)
70 kDa
349
349
47.3%
68
26.8 ± 12.8
37.6 ± 11.4
43.3 ± 11.8
Uncharacterized protein ACSL1
F1RSZ3_PIG
78 kDa
110
110
21.7%
162
8.5 ± 4.2
11.2 ± 5.6
8.0 ± 4.1
Uncharacterized protein LOC100519752
F1RT47_PIG
44 kDa
0
0
8.1%
18
0.0 ± 0.0
0.8 ± 1.1
0.3 ± 0.8
Uncharacterized protein ACSF2
F1RT96_PIG
67 kDa
10
10
4.3%
2
0.7 ± 1.0
0.4 ± 0.9
0.0 ± 0.0
Uncharacterized protein AIFM1
F1RTH3_PIG
67 kDa
407
407
50.4%
1274
65.2 ± 19.0
80.6 ± 14.0
81.2 ± 16.0
Uncharacterized protein MRPL11
F1RU54_PIG
21 kDa
45
45
45.8%
66
2.7 ± 2.6
5.8 ± 1.5
1.0 ± 1.7
Uncharacterized protein ACOT13
F1RUE0_PIG
12 kDa
53
53
46.5%
93
4.5 ± 3.0
8.4 ± 3.8
4.0 ± 2.5
Uncharacterized protein ALDH5A1
F1RUE3_PIG
58 kDa
47
47
14.5%
78
5.8 ± 4.6
2.4 ± 1.8
2.0 ± 1.8
Uncharacterized protein (Fragment) ECHDC3
F1RUP0_PIG
32 kDa
11
11
13.2%
6
0.0 ± 0.0
2.2 ± 0.4
0.0 ± 0.0
Uncharacterized protein MRPS10
F1RUU2_PIG
23 kDa
12
12
19.4%
73
0.8 ± 1.3
1.0 ± 1.4
0.3 ± 0.8
Uncharacterized protein MSRB2
F1RVI8_PIG
20 kDa
4
4
17.0%
4
1.0 ± 1.5
0.0 ± 0.0
0.0 ± 0.0
Uncharacterized protein NDUFV1
F1RVN1_PIG
51 kDa
379
379
65.7%
2177
118.0 ± 33.0
129.8 ± 12.8
123.3 ± 29.5
Uncharacterized protein MRPS7
F1RVX4_PIG
28 kDa
34
34
23.1%
18
2.0 ± 1.7
2.4 ± 0.5
3.3 ± 1.5
Uncharacterized protein DSP
F1RW75_PIG
308 kDa
2
2
0.7%
11
0.3 ± 0.8
0.0 ± 0.0
0.0 ± 0.0
Electron transfer flavoprotein-ubiquinone
oxidoreductase, mitochondrial
F1RW89_PIG
69 kDa
253
253
35.4%
870
38.3 ± 14.8
40.2 ± 8.2
31.5 ± 4.9
Uncharacterized protein LOC100157053
F1RWL7_PIG
22 kDa
81
81
50.5%
349
17.2 ± 7.0
17.0 ± 2.3
9.3 ± 5.0
Uncharacterized protein NDUFB11
F1RWV4_PIG
17 kDa
35
35
22.1%
232
6.3 ± 3.7
6.8 ± 5.4
10.8 ± 2.1
Uncharacterized protein UBA1
F1RWX8_PIG (+1)
118 kDa
11
11
4.2%
9
1.0 ± 1.1
1.2 ± 1.8
0.0 ± 0.0
Uncharacterized protein BPHL
F1RWY7_PIG
33 kDa
28
28
11.7%
214
1.2 ± 1.3
3.8 ± 1.1
1.5 ± 1.8
Uncharacterized protein ECI2
F1RWZ4_PIG
44 kDa
29.9%
185
19.5 ± 7.6
23.0 ± 3.5
19.5 ± 4.1
Uncharacterized protein PROSC
F1RX84_PIG
30 kDa
28
28
12.0%
21
1.2 ± 1.3
3.2 ± 0.8
2.2 ± 1.2
Uncharacterized protein MRPS28
F1RX97_PIG
14 kDa
6
6
16.9%
83
2.0 ± 3.2
0.0 ± 0.0
0.3 ± 0.8
Uncharacterized protein RMDN1
F1RXD4_PIG
36 kDa
96
96
31.5%
155
7.3 ± 1.5
8.2 ± 3.3
8.3 ± 2.1
Uncharacterized protein DECR1
F1RXF3_PIG
35 kDa
300
300
69.2%
1289
86.5 ± 21.7
75.4 ± 20.5
75.0 ± 8.9
Uncharacterized protein SCO2
F1RXT7_PIG
30 kDa
12
12
8.7%
7
2.2 ± 1.7
0.0 ± 0.0
0.8 ± 1.3
Uncharacterized protein PDP1
F1RY43_PIG
61 kDa
54
54
15.8%
72
4.8 ± 2.0
4.2 ± 3.5
3.3 ± 2.0
Uncharacterized protein ACSS3
F1RYM4_PIG
75 kDa
57
57
18.2%
144
6.0 ± 4.9
4.0 ± 5.5
2.7 ± 2.2
Uncharacterized protein (Fragment) MRPL1
F1RYS1_PIG
31 kDa
30
30
13.3%
27
1.0 ± 1.7
4.0 ± 0.7
1.8 ± 1.0
Uncharacterized protein SLC25A4
F1RZQ6_PIG
33 kDa
322
322
68.1%
2159
107.7 ± 12.7
131.0 ± 14.3
109.5 ± 15.6
Uncharacterized protein BAK1
F1RZR2_PIG
24 kDa
2
2
10.3%
4
0.3 ± 0.8
0.0 ± 0.0
0.0 ± 0.0
Uncharacterized protein MRPS2
F1S001_PIG
32 kDa
4
4
5.9%
11
0.0 ± 0.0
0.4 ± 0.9
0.3 ± 0.8
Uncharacterized protein NDUFS6
F1S031_PIG
13 kDa
76
76
61.8%
244
18.2 ± 5.6
17.6 ± 4.6
19.3 ± 6.9
Uncharacterized protein HRSP12
F1S0M2_PIG
14 kDa
19
19
27.0%
13
0.5 ± 1.2
2.8 ± 1.9
1.2 ± 1.3
Cytochrome c oxidase subunit 6C COX6C
F1S0P0_PIG
9 kDa
95
95
54.7%
501
21.7 ± 7.2
18.6 ± 2.5
17.2 ± 5.6
Uncharacterized protein PFDN2
F1S192_PIG (+1)
17 kDa
10
10
16.9%
9
0.7 ± 1.0
0.4 ± 0.9
0.8 ± 1.3
Uncharacterized protein COA3
F1S1F3_PIG
12 kDa
44
44
29.2%
59
5.3 ± 1.8
4.8 ± 1.1
4.3 ± 2.7
Uncharacterized protein TIMM8A
F1S1L1_PIG
11 kDa
32
32
38.1%
36
2.3 ± 2.0
3.0 ± 3.1
2.2 ± 1.8
Ferrochelatase (Fragment) FECH
F1S1X4_PIG
42 kDa
35
35
16.4%
45
2.3 ± 2.1
1.8 ± 1.8
3.5 ± 2.1
Uncharacterized protein PTRH2
F1S227_PIG
19 kDa
6
6
16.8%
21
0.0 ± 0.0
0.6 ± 1.3
0.7 ± 1.0
4-trimethylaminobutyraldehyde dehydrogenase
F1S232_PIG
65 kDa
4
4
4.0%
6
0.3 ± 0.8
0.4 ± 0.9
0.0 ± 0.0
Uncharacterized protein MRPL13
F1S286_PIG
21 kDa
44
44
29.8%
90
2.7 ± 1.8
5.2 ± 2.7
2.0 ± 2.2
Isocitrate dehydrogenase [NAD] subunit,
mitochondrial
F1S297_PIG
43 kDa
95
95
38.3%
259
13.0 ± 3.9
17.0 ± 5.2
9.0 ± 3.3
Peptidyl-prolyl cis-trans isomerase
F1S2E3_PIG
22 kDa
106
106
44.0%
313
10.5 ± 2.9
20.4 ± 3.5
14.8 ± 5.9
Uncharacterized protein (Fragment) PDF
F1S391_PIG
25 kDa
2
2
12.7%
6
0.3 ± 0.8
0.0 ± 0.0
0.0 ± 0.0
Uncharacterized protein CYB5B
F1S393_PIG
16 kDa
17
17
26.4%
44
0.3 ± 0.8
1.8 ± 1.1
1.0 ± 1.1
Uncharacterized protein F1S3B0
F1S3B0_PIG
26 kDa
124
124
60.5%
98
8.8 ± 4.3
9.2 ± 1.6
8.7 ± 1.9
Peptidyl-prolyl cis-trans isomerase NIMA
interacting 1
F1S3G5_PIG
18 kDa
6
6
22.7%
4
0.7 ± 1.0
0.4 ± 0.9
0.0 ± 0.0
Uncharacterized protein ALDH6A1
F1S3H1_PIG
58 kDa
120
120
26.8%
255
16.8 ± 4.8
22.0 ± 5.8
10.2 ± 4.0
Uncharacterized protein (Fragment) COQ6
F1S3H4_PIG
51 kDa
126
126
31.1%
413
21.8 ± 6.9
20.4 ± 3.3
14.7 ± 2.6
Uncharacterized protein PRDX1
F1S3U9_PIG
22 kDa
97
97
41.6%
205
11.2 ± 2.9
13.0 ± 1.9
10.8 ± 2.9
Cytochrome b-c1 complex subunit 6
F1S3W0_PIG
11 kDa
51
51
67.0%
153
7.0 ± 2.2
11.6 ± 3.8
9.2 ± 6.8
Uncharacterized protein PRDX3
F1S418_PIG
28 kDa
147
147
47.1%
496
45.7 ± 5.6
51.0 ± 2.4
42.3 ± 5.0
Uncharacterized protein (Fragment) SYNJ2BP
F1S4A6_PIG
16 kDa
45
45
33.8%
67
3.0 ± 1.3
4.4 ± 1.1
2.3 ± 1.9
Uncharacterized protein COX16
F1S4A8_PIG
12 kDa
8
8
22.6%
3
0.7 ± 1.0
0.6 ± 1.3
0.3 ± 0.8
Uncharacterized protein (Fragment) CCBL2
F1S4D5_PIG
48 kDa
12
12
8.6%
11
0.7 ± 1.0
3.0 ± 2.8
0.0 ± 0.0
NADH-cytochrome b5 reductase
F1S4N2_PIG
34 kDa
57
57
25.6%
2
3.0 ± 4.0
7.6 ± 1.8
5.8 ± 3.6
Uncharacterized protein (Fragment)
COX7A2L
F1S4V0_PIG
13 kDa
14
14
20.2%
70
5.5 ± 3.3
0.0 ± 0.0
1.7 ± 2.9
Uncharacterized protein DBT
F1S563_PIG
53 kDa
67
67
18.9%
223
6.5 ± 4.5
9.0 ± 5.8
6.5 ± 4.3
Uncharacterized protein LRPPRC
F1S5J1_PIG (+1)
159 kDa
67
67
10.7%
126
5.8 ± 4.0
6.0 ± 4.1
2.5 ± 2.3
Uncharacterized protein IBA57 PE=3 SV=1
F1S5S1_PIG
38 kDa
80
80
36.4%
123
9.2 ± 5.8
10.6 ± 3.6
7.0 ± 1.1
Uncharacterized protein SARS
F1S5Z3_PIG
59 kDa
12
12
7.6%
43
1.0 ± 1.7
2.0 ± 1.9
0.0 ± 0.0
ATP synthase subunit delta, mitochondrial
F1S6Q7_PIG
17 kDa
51
51
20.2%
425
11.8 ± 2.6
29.6 ± 16.7
23.3 ± 5.6
Uncharacterized protein CPT2
F1S764_PIG
74 kDa
91
91
20.1%
73
10.2 ± 6.7
10.2 ± 7.3
8.3 ± 4.7
Isocitrate dehydrogenase [NAD] subunit beta,
mitochondrial
F1S897_PIG
42 kDa
167
167
37.9%
534
33.8 ± 14.9
37.8 ± 9.2
28.5 ± 7.4
Uncharacterized protein MRPS26
F1S8A5_PIG
24 kDa
124
124
56.1%
97
16.0 ± 10.0
10.0 ± 3.4
10.3 ± 3.7
Uncharacterized protein MAVS
F1S8C6_PIG (+1)
55 kDa
60
60
17.4%
11
3.8 ± 1.3
6.6 ± 2.8
4.5 ± 1.6
Uncharacterized protein APEX1
F1S8H5_PIG
35 kDa
14
14
22.7%
54
2.8 ± 2.6
0.6 ± 1.3
0.0 ± 0.0
Uncharacterized protein ADCK3
F1S8Q4_PIG
72 kDa
83
83
17.3%
156
10.8 ± 4.8
11.0 ± 4.5
6.3 ± 2.9
Uncharacterized protein MRPL43
F1S8U4_PIG
18 kDa
11
11
22.0%
78
0.7 ± 1.0
0.4 ± 0.9
0.8 ± 1.3
Uncharacterized protein HOGA1
F1S8X9_PIG
35 kDa
21
21
13.2%
54
1.5 ± 1.8
2.8 ± 0.8
0.7 ± 1.0
Mitochondrial amidoxime reducing component
2
F1S9I9_PIG
38 kDa
4
4
8.9%
3
0.0 ± 0.0
1.8 ± 3.0
0.0 ± 0.0
Uncharacterized protein LOC100739845
F1S9K1_PIG
82 kDa
2
2
2.9%
70
0.0 ± 0.0
0.6 ± 1.3
0.0 ± 0.0
Uncharacterized protein ECSIT
F1SA28_PIG
49 kDa
2
2
5.8%
7
0.5 ± 1.2
0.0 ± 0.0
0.0 ± 0.0
Uncharacterized protein (Fragment)
LOC100517634
F1SA62_PIG
14 kDa
138
138
71.9%
620
38.0 ± 9.7
32.2 ± 2.8
28.5 ± 9.4
Mitochondrial import inner membrane
translocase subunit
F1SA66_PIG
52 kDa
126
126
27.8%
197
11.5 ± 5.5
19.2 ± 5.8
11.0 ± 4.6
Uncharacterized protein ECHS1
F1SAC1_PIG
31 kDa
166
166
43.9%
925
41.5 ± 12.5
66.2 ± 8.5
50.0 ± 14.3
Dihydrolipoyl dehydrogenase
F1SAF0_PIG
54 kDa
283
283
50.9%
289
72.8 ± 18.2
80.8 ± 9.3
72.2 ± 12.1
Uncharacterized protein ATP5L
F1SAK6_PIG
11 kDa
105
105
69.9%
349
19.8 ± 2.8
22.4 ± 3.8
19.7 ± 10.0
Acetyl-coenzyme A synthetase
F1SAS2_PIG
74 kDa
145
145
33.2%
344
11.5 ± 2.3
18.6 ± 6.0
6.5 ± 3.1
Uncharacterized protein (Fragment)
LOC100737714
F1SAZ6_PIG
21 kDa
6
6
11.1%
6
0.7 ± 1.0
0.0 ± 0.0
0.5 ± 1.2
Superoxide dismutase SOD2
F1SB60_PIG
25 kDa
130
130
41.0%
808
40.8 ± 4.6
54.4 ± 7.1
39.7 ± 7.1
Uncharacterized protein MRPL18
F1SB64_PIG
21 kDa
8
8
11.7%
29
1.3 ± 2.1
0.6 ± 1.3
0.3 ± 0.8
Uncharacterized protein NDUFAF5
F1SBJ3_PIG
39 kDa
20
20
7.0%
2
0.7 ± 1.0
1.8 ± 1.1
1.5 ± 1.2
Uncharacterized protein ATP5F1
F1SBN7_PIG
29 kDa
335
335
60.9%
1563
91.5 ± 26.0
106.4 ± 16.3
115.2 ± 29.6
Solute carrier family 16, member 1
(Monocarboxylic acid transporter 1)
F1SBQ5_PIG
54 kDa
45
45
15.8%
126
4.2 ± 3.6
6.0 ± 4.7
4.3 ± 2.6
ATP-dependent Clp protease proteolytic
subunit
F1SBT2_PIG
30 kDa
2
2
9.8%
17
0.3 ± 0.8
0.4 ± 0.9
0.0 ± 0.0
Lon protease homolog, mitochondrial LONP1
F1SBU7_PIG
107 kDa
119
119
16.2%
228
11.0 ± 2.9
14.2 ± 7.7
8.0 ± 3.0
Uncharacterized protein C19orf70
F1SBU8_PIG
13 kDa
79
79
78.8%
159
6.8 ± 3.5
11.4 ± 1.8
11.7 ± 4.5
Uncharacterized protein (Fragment) NDUFB7
F1SCH1_PIG
13 kDa
86
86
50.0%
111
17.2 ± 5.0
19.2 ± 4.5
14.7 ± 3.4
Uncharacterized protein RDH14
F1SCT9_PIG (+1)
37 kDa
2
2
6.3%
6
0.3 ± 0.8
0.0 ± 0.0
0.0 ± 0.0
cAMP-dependent protein kinase catalytic
subunit alpha
F1SD45_PIG
41 kDa
92
92
35.0%
191
7.0 ± 2.2
13.2 ± 2.3
5.8 ± 2.6
Uncharacterized protein NDUFB1
F1SD73_PIG
7 kDa
53
53
82.8%
95
7.3 ± 3.0
11.6 ± 1.5
9.8 ± 1.9
Uncharacterized protein (Fragment)
LOC100739748
F1SD94_PIG
41 kDa
2
2
8.5%
12
0.0 ± 0.0
0.4 ± 0.9
0.0 ± 0.0
Uncharacterized protein GADD45GIP1
F1SD95_PIG
26 kDa
0
0
8.1%
4
0.3 ± 0.8
0.0 ± 0.0
0.0 ± 0.0
Uncharacterized protein ALDH3A2
F1SDC7_PIG
42 kDa
16
16
14.7%
15
2.2 ± 2.4
0.8 ± 1.1
0.0 ± 0.0
Uncharacterized protein HADHB
F1SDN2_PIG
51 kDa
431
431
65.9%
2209
134.7 ± 31.3
155.8 ± 15.8
159.7 ± 19.9
Uncharacterized protein OAT
F1SDP3_PIG
49 kDa
93
93
31.9%
53
4.7 ± 1.4
14.2 ± 5.1
8.7 ± 3.3
Uncharacterized protein TIMM23
F1SDW3_PIG (+1)
22 kDa
33
33
16.7%
46
2.5 ± 1.4
4.6 ± 1.8
2.2 ± 1.7
Uncharacterized protein TGM2
F1SDX6_PIG
77 kDa
206
206
31.4%
247
21.2 ± 10.7
19.4 ± 6.4
31.2 ± 9.6
Uncharacterized protein VDAC1P5
F1SE26_PIG
31 kDa
116
116
32.9%
217
28.5 ± 4.5
36.8 ± 4.1
34.8 ± 4.7
Uncharacterized protein OCIAD1
F1SE83_PIG
22 kDa
83
83
36.8%
142
5.8 ± 2.2
10.0 ± 5.8
7.5 ± 2.5
Uncharacterized protein (Fragment) ACADSB
F1SED0_PIG
48 kDa
255
255
51.9%
911
46.2 ± 13.8
72.0 ± 8.2
64.5 ± 7.1
Glutamate dehydrogenase 1, mitochondrial
F1SEN2_PIG
61 kDa
175
175
31.7%
287
13.3 ± 2.8
17.0 ± 5.9
15.5 ± 5.6
Uncharacterized protein GHITM
F1SEQ3_PIG
37 kDa
18
18
8.4%
23
1.5 ± 2.3
0.4 ± 0.9
3.7 ± 0.8
Uncharacterized protein FAM213A PE=4
SV=1
F1SEQ7_PIG
26 kDa
47
47
22.3%
58
1.3 ± 1.5
7.0 ± 3.5
4.2 ± 0.8
Uncharacterized protein (Fragment)
SLC25A13
F1SF87_PIG
75 kDa
49
49
9.8%
520
2.7 ± 4.2
6.6 ± 4.6
6.7 ± 3.7
Uncharacterized protein LYRM5
F1SFJ7_PIG
11 kDa
10
10
20.0%
37
0.7 ± 1.0
1.0 ± 1.4
0.5 ± 1.2
Succinyl-CoA ligase subunit beta
F1SFR6_PIG (+1)
47 kDa
176
176
47.5%
405
17.5 ± 8.5
34.2 ± 8.4
12.3 ± 4.2
Uncharacterized protein DNAJC19 PE=4
SV=2
F1SGA9_PIG
12 kDa
71
71
50.0%
151
5.3 ± 2.7
5.4 ± 1.7
4.0 ± 2.2
Uncharacterized protein NDUFB5
F1SGC6_PIG
22 kDa
132
132
37.6%
329
17.3 ± 5.3
22.8 ± 6.2
21.0 ± 9.2
Uncharacterized protein MRPL47
F1SGC7_PIG
30 kDa
2
2
9.5%
6
0.3 ± 0.8
0.0 ± 0.0
0.0 ± 0.0
Uncharacterized protein PDHB
F1SGH5_PIG
39 kDa
202
202
62.8%
1846
75.3 ± 28.0
80.8 ± 14.5
72.2 ± 14.9
Catalase
F1SGS9_PIG
60 kDa
52
52
17.6%
197
5.7 ± 2.7
7.0 ± 2.9
0.7 ± 1.6
Uncharacterized protein PDHX
F1SGT3_PIG
54 kDa
155
155
30.6%
337
20.2 ± 5.8
27.2 ± 8.1
18.3 ± 6.4
Uncharacterized protein (Fragment) NDUFS1
F1SHD7_PIG
81 kDa
517
517
60.0%
1719
95.0 ± 20.2
107.4 ± 23.0
111.5 ± 20.2
Pyruvate kinase (Fragment) PKM
F1SHL9_PIG
59 kDa
293
293
61.3%
966
56.7 ± 21.4
65.0 ± 14.7
51.3 ± 18.4
Uncharacterized protein BCL2L13
F1SHR2_PIG
50 kDa
19
19
9.7%
30
1.0 ± 1.7
2.4 ± 1.5
1.3 ± 1.5
Uncharacterized protein (Fragment)
LOC100516841
F1SHU0_PIG
18 kDa
52
52
28.6%
155
7.3 ± 4.0
10.4 ± 6.3
7.5 ± 3.0
Uncharacterized protein (Fragment) ATP5S
F1SHX8_PIG
24 kDa
14
14
9.5%
53
3.8 ± 2.5
1.8 ± 2.7
0.0 ± 0.0
Uncharacterized protein NDUFB3
F1SI50_PIG
11 kDa
59
59
48.0%
137
8.0 ± 3.7
8.2 ± 1.6
9.5 ± 4.2
Uncharacterized protein LOC100522576
F1SI71_PIG (+1)
33 kDa
2
2
7.2%
2
0.5 ± 1.2
0.0 ± 0.0
0.0 ± 0.0
Uncharacterized protein MYBPC3
F1SID7_PIG
141 kDa
1042
1042
69.5%
3582
179.5 ± 42.4
142.6 ± 47.8
139.3 ± 36.8
Uncharacterized protein MTCH2
F1SIE0_PIG
33 kDa
21
21
12.5%
16
2.2 ± 2.7
2.2 ± 2.3
1.7 ± 2.0
Uncharacterized protein NDUFS3
F1SIF2_PIG
30 kDa
358
358
65.5%
2097
100.8 ± 17.6
134.6 ± 11.8
142.2 ± 24.2
Uncharacterized protein STOML2
F1SIH5_PIG
39 kDa
65
65
23.6%
17
6.7 ± 3.9
8.4 ± 3.8
7.3 ± 3.3
Uncharacterized protein NDUFA10
F1SIS9_PIG
40 kDa
168
168
63.6%
1776
78.2 ± 23.3
103.4 ± 14.1
77.3 ± 30.0
Uncharacterized protein COX5A
F1SJ34_PIG
17 kDa
98
98
52.6%
536
45.7 ± 6.4
43.6 ± 3.8
48.8 ± 10.2
NADH-cytochrome b5 reductase 3 (Fragment)
F1SJQ5_PIG (+1)
35 kDa
97
97
28.0%
142
8.2 ± 4.8
8.8 ± 4.4
8.7 ± 2.7
Uncharacterized protein EXOG
F1SJT1_PIG
41 kDa
6
6
9.2%
2
1.0 ± 1.1
0.0 ± 0.0
0.0 ± 0.0
Uncharacterized protein ETFA
F1SJX1_PIG
35 kDa
234
234
69.4%
1437
74.5 ± 20.0
101.8 ± 5.1
82.8 ± 8.6
Isocitrate dehydrogenase [NADP],
mitochondrial (Fragment)
F1SK00_PIG (+1)
47 kDa
389
389
59.8%
3367
184.5 ± 26.7
197.4 ± 23.0
212.2 ± 37.3
GTP:AMP phosphotransferase AK3,
mitochondrial
F1SK45_PIG
26 kDa
155
155
58.6%
293
13.8 ± 2.3
18.8 ± 4.0
18.3 ± 4.2
Uncharacterized protein PLGRKT
F1SK49_PIG
17 kDa
34
34
36.1%
52
2.0 ± 1.9
3.4 ± 3.1
2.2 ± 1.8
Uncharacterized protein NDUFAF3
F1SKI6_PIG
21 kDa
4
4
13.5%
5
0.3 ± 0.8
0.0 ± 0.0
0.5 ± 1.2
Sulfurtransferase
F1SKL2_PIG
33 kDa
80
80
27.6%
146
6.7 ± 3.1
9.2 ± 1.8
4.7 ± 1.4
Uncharacterized protein UQCRC1
F1SKM0_PIG
53 kDa
421
421
59.8%
953
189.5 ± 39.8
224.0 ± 18.6
220.8 ± 35.4
Uncharacterized protein
F1SKY2_PIG
31 kDa
145
145
48.4%
346
12.5 ± 5.6
17.4 ± 1.1
9.7 ± 2.4
Uncharacterized protein LOC100524622
F1SL07_PIG
43 kDa
239
239
46.7%
868
52.7 ± 13.2
61.2 ± 11.8
42.8 ± 6.6
Uncharacterized protein MRPS22
F1SL55_PIG
41 kDa
16
16
11.9%
35
1.2 ± 1.3
1.8 ± 2.0
0.3 ± 0.8
Uncharacterized protein (Fragment) TOMM22
F1SLC2_PIG
15 kDa
44
44
33.8%
23
5.0 ± 3.0
7.4 ± 3.2
7.8 ± 1.8
Uncharacterized protein SPR
F1SLF0_PIG
29 kDa
49
49
30.7%
94
6.2 ± 3.3
8.6 ± 2.2
2.2 ± 2.2
Uncharacterized protein CCT7
F1SLF6_PIG
59 kDa
45
45
17.3%
35
2.8 ± 3.0
5.4 ± 4.4
2.8 ± 2.4
Uncharacterized protein (Fragment) NDUFS4
F1SLQ3_PIG
16 kDa
92
92
51.5%
350
16.3 ± 4.8
13.8 ± 3.1
13.3 ± 3.0
Uncharacterized protein MRRF
F1SLQ7_PIG
29 kDa
68
68
31.7%
141
8.5 ± 5.0
5.8 ± 1.9
7.2 ± 1.9
Uncharacterized protein NDUFA8
F1SLR1_PIG
20 kDa
177
177
79.1%
913
43.5 ± 16.4
42.8 ± 10.0
40.2 ± 11.6
Uncharacterized protein NDUFA5
F1SLY2_PIG
13 kDa
102
102
72.4%
411
20.7 ± 4.9
22.0 ± 5.7
25.8 ± 8.5
Uncharacterized protein NDUFV2
F1SM98_PIG
27 kDa
220
220
60.2%
1119
63.7 ± 18.3
73.6 ± 10.3
62.7 ± 13.0
Succinate dehydrogenase [ubiquinone]
cytochrome b small subunit, mitochondrial
F1SMA9_PIG
17 kDa
15
15
27.7%
151
3.3 ± 3.7
9.2 ± 3.2
3.7 ± 1.9
Acetyltransferase component of pyruvate
dehydrogenase complex
F1SMB2_PIG
69 kDa
188
188
25.5%
15
26.7 ± 8.1
30.6 ± 8.6
24.3 ± 6.7
Uncharacterized protein ATP5H
F1SMF9_PIG
18 kDa
40
40
28.7%
1362
25.0 ± 19.5
15.0 ± 20.5
6.3 ± 15.5
Uncharacterized protein (Fragment)
LOC100526144
F1SMG3_PIG
81 kDa
94
94
12.3%
233
6.7 ± 4.7
8.0 ± 2.8
7.7 ± 1.6
Uncharacterized protein (Fragment) EFHD1
F1SMT0_PIG
29 kDa
54
54
37.3%
15
5.5 ± 4.5
3.6 ± 1.1
2.3 ± 2.7
Uncharacterized protein HSPE1 PE=3 SV=1
F1SMZ6_PIG
11 kDa
106
106
80.4%
390
15.7 ± 2.8
27.2 ± 7.6
16.3 ± 9.6
Uncharacterized protein COQ10B
F1SMZ8_PIG
28 kDa
40
40
15.0%
20
2.0 ± 1.1
2.6 ± 0.5
2.7 ± 0.5
Uncharacterized protein HSDL2
F1SNA8_PIG
45 kDa
166
166
45.0%
578
33.3 ± 10.3
37.0 ± 8.1
30.8 ± 7.9
Uncharacterized protein CHCHD3
F1SNF6_PIG
26 kDa
287
287
69.2%
785
51.3 ± 18.1
47.2 ± 12.9
48.5 ± 6.9
Uncharacterized protein LOC100622200
F1SNL5_PIG
28 kDa
31
31
19.8%
114
4.0 ± 2.4
6.2 ± 2.3
3.2 ± 3.6
Uncharacterized protein (Fragment)
NDUFA12
F1SQP4_PIG
17 kDa
147
147
74.1%
205
42.2 ± 10.5
46.0 ± 10.1
39.3 ± 8.6
Uncharacterized protein (Fragment) SLC25A3
F1SQT3_PIG
40 kDa
126
126
30.6%
501
21.2 ± 3.9
30.2 ± 10.0
28.5 ± 10.4
Aconitate hydratase, mitochondrial (Fragment)
F1SRC5_PIG
84 kDa
539
539
59.4%
1772
95.7 ± 22.1
112.2 ± 26.2
97.3 ± 16.5
NADH dehydrogenase [ubiquinone] 1 alpha
subcomplex subunit 6
F1SRG2_PIG
15 kDa
89
89
59.4%
367
15.5 ± 5.2
17.4 ± 10.2
18.3 ± 7.8
Single-stranded DNA-binding protein SSBP1
F1SRQ7_PIG
17 kDa
66
66
49.3%
80
3.0 ± 2.4
11.8 ± 6.2
12.3 ± 7.5
Uncharacterized protein MRPL46
F1SRT0_PIG
32 kDa
19
19
12.9%
109
1.0 ± 1.1
1.4 ± 1.3
1.0 ± 1.5
Uncharacterized protein GSTK1
F1SRV4_PIG
25 kDa
81
81
39.8%
215
11.2 ± 5.3
16.4 ± 3.4
7.0 ± 2.2
Uncharacterized protein SCO1
F1SS60_PIG
34 kDa
18
18
12.1%
6
1.8 ± 2.1
1.0 ± 1.4
1.0 ± 1.5
Uncharacterized protein LOC100515636
F1SSH8_PIG
116 kDa
485
485
51.2%
216
64.7 ± 24.5
85.4 ± 33.2
55.7 ± 8.5
Uncharacterized protein TIMM9
F1SSK4_PIG
10 kDa
38
38
61.8%
42
2.5 ± 2.3
2.8 ± 1.1
3.5 ± 2.7
Uncharacterized protein IVD
F1SSR4_PIG
47 kDa
143
143
35.9%
414
22.7 ± 6.4
29.2 ± 4.9
20.5 ± 2.4
Uncharacterized protein NDUFAF1
F1SSV5_PIG
30 kDa
34
34
24.7%
35
0.8 ± 1.3
4.0 ± 1.4
2.5 ± 1.6
Uncharacterized protein HINT2
F1STB2_PIG
17 kDa
49
49
40.5%
79
4.5 ± 2.6
11.8 ± 4.9
6.0 ± 2.5
Uncharacterized protein MECR
F1STL4_PIG
41 kDa
30
30
21.0%
28
1.2 ± 1.3
3.6 ± 2.6
1.3 ± 1.5
Uncharacterized protein (Fragment) ME3
F1STS4_PIG
61 kDa
48
48
27.3%
81
4.5 ± 3.9
8.0 ± 4.6
1.3 ± 1.6
NADH dehydrogenase [ubiquinone] 1 subunit
C2 NDUFC2
F1STY1_PIG
14 kDa
97
97
61.5%
89
31.3 ± 6.5
41.6 ± 2.6
30.3 ± 9.7
Uncharacterized protein CHCHD1
F1SU49_PIG
14 kDa
6
6
25.4%
18
0.7 ± 1.0
0.4 ± 0.9
0.0 ± 0.0
Uncharacterized protein LOC100522130
F1SU52_PIG
34 kDa
58
58
31.9%
82
4.0 ± 3.4
6.4 ± 1.3
3.5 ± 1.2
Uncharacterized protein (Fragment) HK1
F1SUF2_PIG
84 kDa
51
51
9.7%
310
5.3 ± 4.8
6.6 ± 4.8
4.7 ± 2.5
Uncharacterized protein NDUFS5
F1SV23_PIG
12 kDa
103
103
78.3%
287
8.2 ± 3.9
21.6 ± 10.9
18.8 ± 10.2
Uncharacterized protein (Fragment) TOMM20
F2Z4X6_PIG (+1)
16 kDa
8
8
22.6%
4
0.0 ± 0.0
1.2 ± 1.8
1.2 ± 1.8
Mitochondrial fission 1 protein
FIS1_HUMAN
17 kDa
4
4
43.4%
126
2.5 ± 6.1
0.0 ± 0.0
0.0 ± 0.0
Fumarate hydratase, mitochondrial
FUMH_PIG
50 kDa
231
231
47.4%
979
34.3 ± 11.4
59.8 ± 10.3
42.5 ± 4.6
FUN14 domain-containing protein 2 FUNDC2
FUND2_PIG
21 kDa
69
69
18.5%
59
5.7 ± 2.3
5.0 ± 1.2
5.2 ± 3.4
Guanine nucleotide-binding protein subunit
beta-2-like 1
GBLP_HUMAN
35 kDa
222
222
75.7%
380
37.5 ± 11.9
37.0 ± 11.4
42.8 ± 11.8
Glutaryl-CoA dehydrogenase, mitochondrial
(Fragment)
GCDH_PIG
45 kDa
7
7
11.3%
33
0.7 ± 1.6
0.0 ± 0.0
0.0 ± 0.0
Phospholipid hydroperoxide glutathione
peroxidase, mitochondrial
GPX4_PIG
22 kDa
31
31
42.9%
16
2.7 ± 1.6
4.0 ± 2.5
1.7 ± 1.9
Stress-70 protein, mitochondrial
GRP75_HUMAN
74 kDa
181
181
38.6%
793
23.8 ± 27.6
47.6 ± 29.2
19.2 ± 30.6
Glutathione S-transferase P GSTP1
GSTP1_PIG
23 kDa
80
80
21.1%
145
7.8 ± 2.5
13.2 ± 2.6
5.5 ± 2.2
3-hydroxyacyl-CoA dehydrogenase type-2
HCD2_HUMAN
27 kDa
27
27
77.1%
22
6.8 ± 6.4
4.8 ± 3.4
6.2 ± 5.2
Hydroxyacyl-coenzyme A dehydrogenase,
mitochondrial
HCDH_PIG
34 kDa
283
283
4.7%
428
91.8 ± 36.3
104.6 ± 11.5
81.5 ± 12.7
Hydroxyacid-oxoacid transhydrogenase,
mitochondrial
HOT_HUMAN
50 kDa
4
4
23.3%
299
1.3 ± 2.2
0.0 ± 0.0
0.0 ± 0.0
Heat shock protein HSP 90-beta
HS90B_HUMAN
83 kDa
84
84
8.5%
114
14.0 ± 9.4
24.0 ± 5.2
17.7 ± 6.9
Serine protease HTRA2, mitochondrial
HTRA2_HUMAN
49 kDa
36
36
8.8%
44
1.8 ± 1.0
3.4 ± 0.5
2.8 ± 1.6
Hexokinase-1
HXK1_HUMAN
102 kDa
28
28
8.6%
151
1.8 ± 4.5
6.2 ± 4.0
1.8 ± 2.9
Uncharacterized protein I3L614
I3L614_PIG
28 kDa
4
4
29.3%
602
0.0 ± 0.0
2.2 ± 4.9
0.0 ± 0.0
Uncharacterized protein MRPS25
I3L6Z8_PIG
11 kDa
18
18
36.5%
4
0.3 ± 0.8
0.8 ± 1.1
2.5 ± 1.5
Uncharacterized protein I3L7T8
I3L7T8_PIG
11 kDa
92
92
57.7%
1297
68.8 ± 11.1
90.6 ± 10.1
82.7 ± 8.5
Uncharacterized protein TPP1
I3L812_PIG
62 kDa
2
2
7.2%
2
0.3 ± 0.8
0.0 ± 0.0
0.0 ± 0.0
Uncharacterized protein (Fragment)
SLC25A12
I3L8T2_PIG
46 kDa
218
218
57.0%
483
29.2 ± 3.8
33.0 ± 7.3
30.0 ± 8.1
Uncharacterized protein NDUFAF2
I3L8Y0_PIG
10 kDa
19
19
76.5%
46
1.7 ± 3.2
1.0 ± 1.4
1.0 ± 1.1
Uncharacterized protein (Fragment)
I3L9E4_PIG
19 kDa
14
14
54.1%
78
0.0 ± 0.0
3.4 ± 3.4
0.0 ± 0.0
Uncharacterized protein (Fragment) BSG
I3L9F1_PIG
24 kDa
91
91
27.1%
231
10.3 ± 2.9
17.2 ± 3.6
14.0 ± 1.8
Uncharacterized protein NDUFAF4
I3L9T7_PIG
21 kDa
37
37
45.3%
231
4.3 ± 2.3
5.2 ± 2.2
4.8 ± 2.6
Uncharacterized protein (Fragment)
I3LAI1_PIG
28 kDa
97
97
26.2%
783
8.3 ± 12.9
48.8 ± 5.3
40.3 ± 11.7
Uncharacterized protein (Fragment) TIMM50
I3LC09_PIG
49 kDa
77
77
17.0%
151
7.0 ± 4.2
9.2 ± 1.5
9.3 ± 2.4
Uncharacterized protein LOC100525869
I3LCI0_PIG
33 kDa
84
84
32.5%
651
26.8 ± 10.3
31.2 ± 9.0
25.0 ± 3.8
Pyruvate dehydrogenase E1 component
subunit alpha
I3LCI2_PIG
43 kDa
274
274
62.6%
1281
54.7 ± 16.9
65.0 ± 16.2
56.0 ± 6.4
Uncharacterized protein FIS1
I3LD01_PIG
19 kDa
105
105
52.4%
128
26.8 ± 4.4
36.8 ± 2.5
30.0 ± 6.3
Uncharacterized protein SIRT5
I3LD45_PIG
15 kDa
19
19
21.6%
15
0.7 ± 1.0
2.2 ± 0.4
0.8 ± 1.3
Uncharacterized protein (Fragment) COQ3
I3LD55_PIG
38 kDa
82
82
23.4%
270
9.5 ± 2.0
14.4 ± 4.0
11.3 ± 3.6
Succinate dehydrogenase [ubiquinone] ironsulfur subunit, mitochondrial
I3LDC1_PIG
32 kDa
151
151
40.4%
1126
56.3 ± 9.0
61.4 ± 5.4
55.7 ± 12.6
Uncharacterized protein NDUFB10
I3LDC3_PIG
21 kDa
216
216
80.7%
1450
78.5 ± 18.8
87.0 ± 12.4
71.7 ± 17.1
Isocitrate dehydrogenase [NADP] cytoplasmic
(Fragment)
I3LDC7_PIG
48 kDa
39
39
12.1%
210
4.7 ± 2.3
7.2 ± 2.4
4.3 ± 3.8
Uncharacterized protein (Fragment) PGAM5
I3LE16_PIG
26 kDa
57
57
26.1%
168
5.7 ± 2.4
6.4 ± 1.8
5.2 ± 2.5
Uncharacterized protein HSD17B4
I3LEF8_PIG
45 kDa
55
55
22.0%
51
4.3 ± 3.9
7.6 ± 4.8
2.7 ± 1.5
Uncharacterized protein (Fragment) MRPS6
I3LEJ9_PIG
14 kDa
16
16
32.3%
31
1.5 ± 2.3
0.4 ± 0.9
1.0 ± 1.1
Uncharacterized protein STRAP
I3LEQ7_PIG
39 kDa
4
4
9.1%
18
0.3 ± 0.8
0.4 ± 0.9
0.0 ± 0.0
Cytochrome c oxidase subunit 4 isoform 1,
mitochondrial
I3LER5_PIG
20 kDa
202
202
61.5%
618
40.3 ± 13.8
57.4 ± 5.5
46.5 ± 18.1
Uncharacterized protein BCS1L
I3LFK0_PIG
47 kDa
13
13
9.8%
27
0.3 ± 0.8
3.0 ± 4.5
1.7 ± 2.0
Uncharacterized protein (Fragment)
I3LG46_PIG
26 kDa
74
74
24.4%
161
10.5 ± 3.6
13.6 ± 1.1
10.8 ± 4.4
Uncharacterized protein NDUFA11
I3LGM4_PIG
15 kDa
88
88
68.1%
158
13.0 ± 4.0
21.4 ± 5.9
16.8 ± 7.0
Uncharacterized protein (Fragment) NDUFS7
I3LHL4_PIG
24 kDa
66
66
31.2%
389
20.8 ± 8.3
19.0 ± 2.4
13.2 ± 4.0
Uncharacterized protein (Fragment)
I3LHS7_PIG
35 kDa
177
177
49.8%
755
40.8 ± 12.1
60.6 ± 4.5
36.3 ± 4.4
Uncharacterized protein (Fragment) MYO1C
I3LIL4_PIG
122 kDa
42
42
10.2%
41
3.5 ± 2.3
3.8 ± 4.4
2.0 ± 1.7
Uncharacterized protein HMGCL
I3LIL5_PIG
34 kDa
73
73
30.5%
208
10.7 ± 4.1
8.4 ± 8.3
8.3 ± 4.6
Uncharacterized protein (Fragment) CISD3
I3LIT8_PIG (+1)
13 kDa
52
52
36.2%
272
12.3 ± 2.7
9.8 ± 3.3
7.2 ± 1.9
Uncharacterized protein LOC100623793
I3LJ05_PIG
29 kDa
145
145
49.8%
645
25.0 ± 10.6
28.0 ± 3.9
15.0 ± 1.8
Uncharacterized protein ECH1
I3LJJ4_PIG
25 kDa
119
119
46.1%
411
20.2 ± 3.5
30.2 ± 6.3
23.7 ± 3.1
Uncharacterized protein TMEM126A
I3LJK4_PIG
22 kDa
12
12
9.2%
51
0.3 ± 0.8
1.6 ± 1.5
0.7 ± 1.0
Uncharacterized protein HSPB7
I3LJU7_PIG
18 kDa
42
42
37.9%
122
3.7 ± 3.2
2.2 ± 2.3
10.2 ± 3.7
Uncharacterized protein (Fragment) ACO1
I3LJW4_PIG
99 kDa
50
50
8.1%
5
4.7 ± 1.6
4.8 ± 1.3
2.3 ± 1.2
Uncharacterized protein (Fragment) ACSF3
I3LK72_PIG
48 kDa
26
26
14.0%
46
3.2 ± 1.9
1.0 ± 1.4
0.7 ± 1.0
Uncharacterized protein FAM162A
I3LKD2_PIG
18 kDa
95
95
43.9%
359
13.2 ± 7.1
18.4 ± 5.0
14.8 ± 7.3
Uncharacterized protein (Fragment)
LOC100520636
I3LLE3_PIG
75 kDa
504
504
57.3%
1346
75.0 ± 15.4
105.4 ± 19.7
76.7 ± 10.5
Uncharacterized protein DNAJA3
I3LLG4_PIG
51 kDa
59
59
18.5%
135
4.8 ± 3.4
5.8 ± 2.6
3.3 ± 2.5
Uncharacterized protein ECI1
I3LLH8_PIG
19 kDa
51
51
29.7%
245
12.2 ± 3.9
16.2 ± 5.4
10.2 ± 2.8
Uncharacterized protein
I3LLI0_PIG
24 kDa
322
322
69.7%
4058
247.8 ± 67.3
189.2 ± 33.2
270.8 ± 64.6
Uncharacterized protein ETHE1
I3LLM9_PIG
14 kDa
22
22
28.0%
35
2.2 ± 2.4
2.4 ± 0.9
0.8 ± 2.0
Uncharacterized protein SAMM50
I3LLW3_PIG
40 kDa
2
2
0.0%
2
0.0 ± 0.0
0.0 ± 0.0
0.0 ± 0.0
Uncharacterized protein LOC100512831
I3LLY6_PIG
44 kDa
10
10
8.8%
62
0.7 ± 1.0
1.0 ± 1.4
0.3 ± 0.8
Uncharacterized protein PPA2
I3LM66_PIG
13 kDa
12
12
34.5%
30
1.2 ± 1.8
3.4 ± 3.4
0.3 ± 0.8
Uncharacterized protein (Fragment) ABHD10
I3LMP2_PIG
34 kDa
8
8
11.4%
20
0.5 ± 1.2
0.8 ± 1.1
0.3 ± 0.8
Uncharacterized protein POLDIP2
I3LMX3_PIG (+1)
42 kDa
13
13
12.7%
33
1.2 ± 2.0
1.6 ± 1.7
0.0 ± 0.0
Uncharacterized protein (Fragment) ALDH4A1
I3LNB4_PIG
56 kDa
176
176
40.8%
8
17.2 ± 6.9
29.6 ± 9.2
15.8 ± 4.9
Uncharacterized protein ACAT1
I3LP02_PIG
46 kDa
366
366
61.2%
1889
72.0 ± 22.1
86.2 ± 16.1
74.3 ± 14.1
Malate dehydrogenase
I3LP41_PIG (+1)
36 kDa
196
196
70.4%
4330
243.5 ± 35.3
257.8 ± 29.0
263.3 ± 30.8
Uncharacterized protein TMEM70
I3LPM1_PIG
28 kDa
33
33
22.8%
18
1.3 ± 1.5
3.2 ± 1.6
2.5 ± 1.2
Fumarate hydratase, mitochondrial
I3LPP1_PIG
50 kDa
252
252
50.6%
968
37.5 ± 10.1
69.4 ± 11.5
49.3 ± 4.5
Uncharacterized protein NDUFB4
I3LPW0_PIG
15 kDa
110
110
55.0%
609
14.5 ± 3.7
36.8 ± 24.9
23.7 ± 10.5
Uncharacterized protein PHB2
I3LQN4_PIG
33 kDa
289
289
70.6%
1170
70.8 ± 21.6
85.4 ± 11.7
103.3 ± 27.9
Uncharacterized protein MRPL9
I3LR45_PIG
30 kDa
15
15
13.1%
102
0.0 ± 0.0
2.2 ± 1.5
1.0 ± 1.1
Uncharacterized protein (Fragment) NDUFV3
I3LRR4_PIG
42 kDa
217
217
50.4%
731
42.7 ± 19.8
38.2 ± 6.8
42.3 ± 6.9
ATP-dependent (S)-NAD(P)H-hydrate
dehydratase
I3LS60_PIG
36 kDa
111
111
36.6%
286
7.8 ± 4.0
11.0 ± 5.1
8.2 ± 3.5
Uncharacterized protein TIMM13
I3LS73_PIG (+1)
11 kDa
21
21
43.2%
11
2.5 ± 2.1
1.0 ± 1.4
0.8 ± 1.3
Adenylate kinase 2, mitochondrial
I3LSI3_PIG
27 kDa
139
139
66.8%
321
16.0 ± 9.1
19.6 ± 4.0
16.8 ± 5.7
Uncharacterized protein (Fragment) IMMT
I3LSM7_PIG
81 kDa
599
599
61.7%
93
60.2 ± 20.5
81.0 ± 10.9
67.3 ± 17.2
Uncharacterized protein MRPL12
I3LSY1_PIG
9 kDa
2
2
17.9%
22
0.0 ± 0.0
0.4 ± 0.9
0.0 ± 0.0
Uncharacterized protein MCCC1
I3LT90_PIG
80 kDa
2
2
2.4%
4
0.0 ± 0.0
0.4 ± 0.9
0.0 ± 0.0
Uncharacterized protein (Fragment) I3LTC0
I3LTC0_PIG
18 kDa
69
69
54.2%
112
6.7 ± 3.8
9.8 ± 4.8
6.5 ± 1.8
Cytochrome c oxidase subunit 6A,
mitochondrial
I3LTV6_PIG
11 kDa
36
36
32.0%
134
20.7 ± 6.0
21.0 ± 1.2
16.7 ± 4.7
Uncharacterized protein (Fragment) IARS2
I3LUE8_PIG
61 kDa
9
9
5.2%
78
0.0 ± 0.0
4.6 ± 3.1
0.0 ± 0.0
Uncharacterized protein (Fragment) ACAD9
I3LUR5_PIG
49 kDa
5
5
6.6%
6
0.7 ± 1.6
1.2 ± 2.7
0.0 ± 0.0
Uncharacterized protein LOC100516656
I3LUZ8_PIG
17 kDa
8
8
20.2%
34
2.2 ± 2.8
0.4 ± 0.9
0.0 ± 0.0
GrpE protein homolog LOC100622145
I3LVG4_PIG
24 kDa
31
31
14.3%
74
2.7 ± 2.3
5.0 ± 0.7
4.7 ± 1.4
Isocitrate dehydrogenase [NAD] subunit
gamma, mitochondrial (Fragments)
IDH3G_PIG
11 kDa
6
6
41.5%
220
1.7 ± 2.7
0.0 ± 0.0
0.0 ± 0.0
Translation initiation factor IF-2, mitochondrial
IF2M_HUMANDECOY
?
2
2
0.0%
5
0.3 ± 0.8
0.0 ± 0.0
0.0 ± 0.0
Uncharacterized protein ADHFE1
K7GMB9_PIG
45 kDa
66
66
11.2%
220
16.3 ± 4.3
11.0 ± 10.5
0.0 ± 0.0
Uncharacterized protein ILF3
K7GP99_PIG
87 kDa
24
24
11.0%
46
3.0 ± 2.8
2.4 ± 2.9
0.0 ± 0.0
cAMP-dependent protein kinase catalytic
subunit beta
KAPCB_HUMAN
41 kDa
28
28
18.5%
146
0.0 ± 0.0
3.4 ± 4.8
4.5 ± 2.7
Creatine kinase M-type
KCRM_PIG
43 kDa
384
384
69.0%
3287
164.2 ± 25.4
254.4 ± 15.8
171.7 ± 39.6
L-lactate dehydrogenase A chain
LDHA_PIG
37 kDa
57
57
25.0%
82
11.2 ± 5.8
13.2 ± 2.2
12.8 ± 1.8
Methylmalonate-semialdehyde dehydrogenase
[acylating], mitochondrial
MMSA_HUMAN
58 kDa
8
8
10.5%
258
0.0 ± 0.0
1.8 ± 4.0
0.7 ± 1.6
Phosphate carrier protein, mitochondrial
MPCP_HUMAN
40 kDa
37
37
18.2%
755
8.2 ± 6.9
7.0 ± 4.4
4.7 ± 7.5
Metaxin-2 MTX2
MTX2_PIG
30 kDa
97
97
36.3%
44
12.3 ± 7.2
14.4 ± 2.7
9.8 ± 3.4
Methylmalonyl-CoA mutase, mitochondrial
MUTA_PIG
83 kDa
10
10
2.8%
17
0.7 ± 1.6
2.2 ± 2.0
0.5 ± 1.2
Myomesin-2
MYOM2_HUMAN
165 kDa
56
56
5.8%
77
3.3 ± 2.9
3.2 ± 3.4
6.2 ± 2.6
NADH dehydrogenase [ubiquinone] iron-sulfur
protein 3, mitochondrial
NDUS3_HUMAN
30 kDa
77
77
41.7%
2131
0.0 ± 0.0
41.0 ± 38.2
37.2 ± 42.5
NADH dehydrogenase [ubiquinone] iron-sulfur
protein 4, mitochondrial
NDUS4_HUMAN
20 kDa
74
74
33.8%
214
12.3 ± 4.0
11.0 ± 3.5
9.3 ± 1.5
NADH dehydrogenase [ubiquinone] iron-sulfur
protein 8, mitochondrial
NDUS8_HUMAN
24 kDa
72
72
16.8%
525
18.0 ± 4.0
18.0 ± 4.4
15.3 ± 4.5
NFU1 iron-sulfur cluster scaffold homolog,
mitochondrial
NFU1_HUMAN
28 kDa
6
6
12.0%
17
0.0 ± 0.0
1.4 ± 1.3
0.0 ± 0.0
Protein NipSnap homolog 2
NIPS2_HUMAN
34 kDa
128
128
39.0%
667
29.3 ± 9.9
32.8 ± 5.1
26.8 ± 4.3
Omega-amidase NIT2
NIT2_HUMAN
31 kDa
69
69
48.0%
254
5.5 ± 5.2
7.8 ± 4.4
6.5 ± 2.1
NAD(P) transhydrogenase, mitochondrial
NNTM_HUMAN
114 kDa
170
170
42.0%
449
12.5 ± 4.7
16.8 ± 7.5
12.3 ± 4.0
NADH-ubiquinone oxidoreductase chain 1
NU1M_PIG
36 kDa
21
21
8.8%
14
0.3 ± 0.8
4.4 ± 3.2
3.7 ± 4.5
OCIA domain-containing protein 1
OCAD1_HUMAN
28 kDa
35
35
13.0%
68
1.3 ± 3.3
9.2 ± 0.8
8.0 ± 1.4
2-oxoglutarate dehydrogenase, mitochondrial
ODO1_HUMAN
116 kDa
287
287
51.0%
1149
27.0 ± 31.2
60.4 ± 37.7
30.8 ± 24.8
Dihydrolipoyllysine-residue succinyltransferase
component of 2-oxoglutarate dehydrogenase
complex, mitochondrial
ODO2_PIG
49 kDa
195
195
29.0%
74
61.3 ± 6.9
71.6 ± 9.5
60.7 ± 7.0
Pyruvate dehydrogenase E1 component
subunit alpha, testis-specific form,
mitochondrial
ODPAT_HUMAN
43 kDa
22
22
63.0%
1176
5.5 ± 8.6
8.2 ± 7.9
0.0 ± 0.0
Dynamin-like 120 kDa protein, mitochondrial
OPA1_HUMAN
112 kDa
18
18
6.0%
13
1.3 ± 1.6
1.0 ± 1.4
0.8 ± 1.3
Protein DJ-1
PARK7_HUMAN
20 kDa
99
99
50.8%
295
13.3 ± 6.3
14.8 ± 4.8
10.0 ± 2.6
Propionyl-CoA carboxylase alpha chain,
mitochondrial
PCCA_HUMAN
80 kDa
30
30
8.5%
75
1.7 ± 2.0
3.4 ± 2.4
1.3 ± 1.6
Propionyl-CoA carboxylase beta chain,
mitochondrial
PCCB_PIG
59 kDa
79
79
23.0%
88
8.2 ± 5.5
13.0 ± 3.4
4.7 ± 1.8
Pyruvate dehydrogenase phosphatase
regulatory subunit, mitochondrial
PDPR_HUMAN
99 kDa
16
16
15.9%
4
0.0 ± 0.0
0.4 ± 0.9
0.0 ± 0.0
Prohibitin
PHB_HUMAN
30 kDa
118
118
69.5%
990
53.2 ± 15.2
59.4 ± 6.2
58.3 ± 12.4
Prohibitin-2
PHB2_HUMAN
33 kDa
69
69
55.5%
1472
0.0 ± 0.0
23.6 ± 32.5
28.5 ± 31.4
PP2AA_HUMAN
36 kDa
38
38
30.4%
102
1.7 ± 2.7
4.4 ± 2.7
2.5 ± 3.9
Serine/threonine-protein phosphatase 2A
catalytic subunit alpha isoform
Serine/threonine-protein phosphatase 2A
catalytic subunit beta isoform
PP2AB_HUMAN
36 kDa
39
39
30.4%
32
1.7 ± 2.7
4.0 ± 2.6
2.2 ± 3.7
Protein phosphatase 1E
PPM1E_HUMAN
85 kDa
20
20
3.0%
12
2.3 ± 1.9
2.4 ± 2.2
1.5 ± 1.8
Proteasome subunit beta type-3
PSB3_HUMAN
23 kDa
29
29
23.4%
47
1.3 ± 2.2
7.0 ± 3.4
2.7 ± 2.3
Polymerase I and transcript release factor
PTRF_HUMAN
43 kDa
188
188
33.8%
592
39.3 ± 4.7
40.8 ± 10.0
43.7 ± 7.1
Ubiquinol-cytochrome c reductase complex
Q2EN79_PIG
7 kDa
39
39
51.6%
154
4.7 ± 1.2
6.4 ± 0.5
4.0 ± 2.2
NADH dehydrogenase 1 beta subcomplex 6
LOC733605
Q2EN80_PIG
16 kDa
86
86
48.4%
10
12.2 ± 5.0
18.0 ± 3.4
15.3 ± 8.6
Mitochondrial creatine kinase 2
Q2HYU1_PIG
47 kDa
417
417
65.4%
106
138.2 ± 45.6
156.0 ± 28.4
160.2 ± 20.9
Cytochrome c oxidase subunit 2
Q69GF7_PIG
26 kDa
57
57
28.4%
328
15.5 ± 9.8
23.0 ± 6.8
21.5 ± 9.4
Cytochrome b-c1 complex subunit 2,
mitochondrial
QCR2_HUMAN
48 kDa
87
87
17.4%
2789
35.3 ± 6.7
40.0 ± 9.8
48.3 ± 8.5
Cytochrome b-c1 complex subunit 7
QCR7_HUMAN
14 kDa
73
73
26.1%
185
14.0 ± 2.5
13.4 ± 2.6
15.7 ± 5.2
60S ribosomal protein L10a
RL10A_HUMAN
25 kDa
49
49
26.3%
123
7.7 ± 4.3
5.0 ± 3.8
2.8 ± 2.5
60S ribosomal protein L35a
RL35A_HUMAN
13 kDa
8
8
20.0%
13
1.0 ± 1.7
0.4 ± 0.9
0.5 ± 1.2
39S ribosomal protein L12, mitochondrial
RM12_HUMAN
21 kDa
52
52
17.7%
76
3.5 ± 1.4
3.2 ± 1.1
2.7 ± 0.5
39S ribosomal protein L22, mitochondrial
RM22_HUMAN
24 kDa
2
2
10.2%
10
0.3 ± 0.8
0.0 ± 0.0
0.0 ± 0.0
40S ribosomal protein S14
RS14_HUMAN
16 kDa
54
54
43.0%
43
5.5 ± 4.3
2.6 ± 2.6
5.3 ± 3.0
40S ribosomal protein S19
RS19_HUMAN
16 kDa
182
182
58.6%
372
23.2 ± 8.0
25.6 ± 3.6
24.0 ± 8.9
28S ribosomal protein S28, mitochondrial
RT28_HUMAN
21 kDa
27
27
16.0%
44
3.8 ± 2.8
2.6 ± 1.9
0.8 ± 1.3
Reticulon-4-interacting protein 1, mitochondrial
RT4I1_HUMAN
44 kDa
4
4
16.7%
20
0.7 ± 1.6
0.0 ± 0.0
0.0 ± 0.0
Sorting and assembly machinery component
50 homolog
SAM50_HUMAN
52 kDa
4
4
6.8%
9
0.3 ± 0.8
0.6 ± 1.3
0.0 ± 0.0
Succinyl-CoA:3-ketoacid coenzyme A
transferase 1, mitochondrial
SCOT1_PIG
56 kDa
270
270
44.8%
560
34.0 ± 13.6
58.8 ± 7.6
38.8 ± 9.4
Succinate dehydrogenase [ubiquinone]
flavoprotein subunit, mitochondrial
SDHA_PIG
73 kDa
294
294
49.2%
1105
60.8 ± 19.1
56.2 ± 10.7
53.7 ± 9.6
Staphylococcal nuclease domain-containing
protein 1
SND1_HUMAN
102 kDa
8
8
3.7%
55
0.5 ± 1.2
1.8 ± 2.7
0.3 ± 0.8
Superoxide dismutase [Cu-Zn]
SODC_PIG
16 kDa
5
5
22.9%
4
0.7 ± 1.6
0.4 ± 0.9
0.0 ± 0.0
Succinyl-CoA ligase [ADP/GDP-forming]
subunit alpha, mitochondrial
SUCA_PIG
36 kDa
123
123
37.0%
701
27.3 ± 8.9
33.2 ± 6.1
25.5 ± 3.3
Transcription factor A, mitochondrial
TFAM_PIG
29 kDa
105
105
50.4%
201
15.2 ± 5.7
12.0 ± 3.5
11.5 ± 4.5
Acetyl-CoA acetyltransferase, mitochondrial
THIL_HUMAN
45 kDa
76
76
21.8%
1309
10.5 ± 11.9
15.2 ± 8.7
12.8 ± 6.7
Mitochondrial import inner membrane
translocase subunit Tim8
TIM8B_HUMAN
9 kDa
4
4
26.5%
2
0.3 ± 0.8
0.0 ± 0.0
0.3 ± 0.8
Mitochondrial import receptor subunit TOM7
homolog
TOM7_PIG
6 kDa
4
4
45.5%
15
0.0 ± 0.0
0.8 ± 1.1
0.0 ± 0.0
Mitochondrial import receptor subunit TOM70
TOM70_HUMAN
67 kDa
37
37
8.1%
90
3.7 ± 2.3
7.8 ± 1.5
1.5 ± 2.3
Voltage-dependent anion-selective channel
protein 1
VDAC1_PIG
31 kDa
318
318
84.8%
1336
72.5 ± 4.3
138.8 ± 50.6
126.7 ± 27.5
Voltage-dependent anion-selective channel
protein 2
VDAC2_HUMAN
(+1)
32 kDa
182
182
53.4%
467
44.3 ± 3.7
53.8 ± 6.6
55.8 ± 8.7
Supplemental Table 3. Uniprot reference number and pig entrez gene ID for mitochondrial proteins identified
Identified Proteins
Uniprot accession ID
14-3-3 protein epsilon
Serine/threonine-protein phosphatase 2A 65 kDa regulatory
subunit A alpha isoform
1433E_HUMAN
Pig entrez gene
ID
P62258
P30153
XP_005658807.1
2AAA_HUMAN (+1)
3-hydroxyisobutyrate dehydrogenase, mitochondrial
3HIDH_HUMAN
Uncharacterized protein A0A075B7H9
A0A075B7H9_PIG
Mitochondrial NDUFA4
A1XQS3_PIG
COX8H
A1XQT4_PIG
Estradiol 17-beta-dehydrogenase 8
ATP synthase, H+ transporting, mitochondrial F1 complex,
epsilon subunit
A5D9P1_PIG
Aspartate aminotransferase, mitochondrial
Long-chain specific acyl-CoA dehydrogenase,
mitochondrial
Medium-chain specific acyl-CoA dehydrogenase,
mitochondrial
AATM_PIG
Acyl-CoA-binding protein
ACBP_PIG
Acyl carrier protein, mitochondrial
ACPM_HUMAN (+1)
NP_058587.1
P31937
XP_003134876.3
A0A075B7H9
A1XQS3
A1XQT4
A5D9P1
A5GFX4
A5GFX4_PIG
P00506
P79274
ACADL_PIG
P41367
ACADM_PIG
ADP/ATP translocase 3
ADT3_PIG
AFG3-like protein 2
AFG32_HUMAN
Aldehyde dehydrogenase, mitochondrial
ALDH2_PIG
Arginine and glutamate-rich protein 1
ARGL1_HUMAN
Actin-related protein 2/3 complex subunit 2
Uniprot reference
number
ARPC2_HUMAN
ATPase inhibitor, mitochondrial ATPIF1
ATIF1_PIG
ATP synthase subunit d, mitochondrial
ATP5H_HUMAN
ATP synthase subunit e, mitochondrial
ATP5I_PIG
ATP synthase-coupling factor 6, mitochondrial ATP5J
ATP5J_PIG
ATP synthase subunit a MT-ATP6
ATP6_PIG
ATP synthase protein 8
ATP8_PIG
P12026
O14561
XP_005656819.1
Q6QRN9
Q9Y4W6
XP_003482084.1
Q2XQV4
Q9NWB6
O15144
XP_001927236
NP_001177168.1
Q29307
O75947
Q9MYT8
P13618
Q35915
Q35914
NP_001231613
ATP synthase subunit alpha, mitochondrial
ATPA_PIG
ATP synthase mitochondrial F1 complex assembly factor 1
ATPF1_HUMAN
ATP synthase subunit gamma, mitochondrial
ATPG_HUMAN
ATP synthase subunit f, mitochondrial
ATPK_PIG
ATP synthase subunit O, mitochondrial
ATPO_PIG
Methylglutaconyl-CoA hydratase, mitochondrial
AUHM_HUMAN
Cytochrome b reductase 1 CYBRD1
B2ZPK1_PIG
D-beta-hydroxybutyrate dehydrogenase, mitochondrial
BDH_HUMAN
Brain protein 44
BR44_HUMAN
Brain protein 44-like protein
Succinate dehydrogenase cytochrome b560 subunit,
mitochondrial
BR44L_HUMAN
Cathepsin B
CATB_PIG
Coiled-coil domain-containing protein 58
CCD58_HUMAN (+1)
10 kDa heat shock protein, mitochondrial
Charged multivesicular body protein 2b
CDGSH iron-sulfur domain-containing protein 3,
mitochondrial
P80021
Q5TC12
P36542
XP_003482139
XP_005667840.1
Q95339
Q2EN81
Q13825
XP_001928827.3
B2ZPK1
Q02338
O95563
Q9Y5U8
XP_005670154
XP_003355117
NP_001231793
D0VWV4
C560_PIG
CH10_HUMAN
CHM2B_HUMAN (+1)
A1E295
Q4VC31
P61604
Q9UQN3
XP_003358841
NP_999472.1
NP_001231349
P0C7P0
CISD3_HUMAN
Citrate synthase, mitochondrial
CISY_PIG
Chloride intracellular channel protein 4
CLIC4_HUMAN
Clusterin CLU
CLUS_PIG
Calcium-binding mitochondrial carrier protein Aralar1
Hexaprenyldihydroxybenzoate methyltransferase,
mitochondrial
CMC1_HUMAN
XP_005658995
P00889
Q9Y696
XP_005656284
Q29549
O75746
XP_005667683.1
Q9NZJ6
COQ3_HUMAN
Ubiquinone biosynthesis protein COQ7 homolog
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial
(Fragment)
COQ7_HUMAN
Cytochrome c oxidase subunit 5B, mitochondrial COX5B
COX5B_PIG
Cytochrome c oxidase subunit 7C, mitochondrial
COX7C_PIG
Carnitine O-palmitoyltransferase 1, muscle isoform
CPT1B_PIG
Cytochrome c oxidase subunit 7A1, mitochondrial
CX7A1_PIG
Cytochrome c1, heme protein, mitochondrial
CY1_HUMAN
XP_005674125.1
Q99807
XP_003124309.2
Q95283
COX41_PIG
Q5S3G4
Q1W0Y2
Q8HY46
Q8SPJ9
P08574
XP_003125498
Cytochrome b5 CYB5A
CYB5_PIG
Cytochrome c
CYC_PIG
Acetyl-Coenzyme A acyltransferase 2
D0G0B3_PIG
Cysteine and glycine-rich protein 3
D2SQP3_PIG
N(G),N(G)-dimethylarginine dimethylaminohydrolase 2
DDAH2_HUMAN
ATP-dependent RNA helicase DDX3X
DDX3X_HUMAN (+1)
Dehydrogenase/reductase SDR family member 4
DHRS4_PIG
Dynamin-1-like protein
DNM1L_HUMAN
MACRO domain containing protein 1
E7EBY5_PIG
Trifunctional enzyme subunit alpha, mitochondrial
ECHA_PIG
Trifunctional enzyme subunit beta, mitochondrial
ECHB_HUMAN
Elongation factor 1-beta
EF1B_HUMAN (+1)
Electron transfer flavoprotein subunit alpha, mitochondrial
ETFA_HUMAN
Electron transfer flavoprotein subunit beta
ETFB_PIG
Uncharacterized protein MTFP1
F1RFC8_PIG
Uncharacterized protein USMG5
F1RFD4_PIG
Elongation factor Tu
F1RFI1_PIG
Uncharacterized protein OMC
F1RFX9_PIG
Uncharacterized protein MRPS34
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex
subunit 2
F1RG19_PIG
Stress-70 protein, mitochondrial
F1RGJ3_PIG
Uncharacterized protein COA6
F1RGW3_PIG
Uncharacterized protein MRPL24
F1RHJ1_PIG
Uncharacterized protein GLOD4
F1RHJ9_PIG
Catechol O-methyltransferase
F1RHN3_PIG
Uncharacterized protein MRPL16
F1RI89_PIG
P00172
P62895
D0G0B3
D2SQP3
O95865
O00571
O00429
F1RIR7_PIG
F1RIS6_PIG
Uncharacterized protein CHCHD2
F1RIU9_PIG
XP_003481715
E7EBY5
Q29554
P55084
P24534
P13804
Q6UAQ8
F1RFC8
F1RFD4
F1RFI1
F1RFX9
F1RG19
F1RGE3
Uncharacterized protein (Fragment) MMAB
XP_005673618
Q8WNV7
F1RGE3_PIG
Uncharacterized protein BCKDK
AJW77606.1
F1RGJ3
F1RGW3
F1RHJ1
F1RHJ9
F1RHN3
F1RI89
F1RIR7
F1RIS6
F1RIU9
NP_999131.1
NP_001230453
NP_001231332
Uncharacterized protein CBR4
F1RIX8_PIG
Uncharacterized protein LOC100525876
Short-chain-specific acyl-CoA dehydrogenase,
mitochondrial
F1RJE4_PIG
Uncharacterized protein (Fragment) ABHD11
F1RJM8_PIG
Uncharacterized protein DNAJC30
F1RJN1_PIG
Succinyl-CoA ligase subunit beta SUCLA2
F1RK10_PIG
Uncharacterized protein TRAP1
F1RK45_PIG
Uncharacterized protein (Fragment) LOC100513918
F1RK50_PIG
Uncharacterized protein MRPL40
F1RK59_PIG
Succinate dehydrogenase assembly factor 2, mitochondrial
F1RKQ9_PIG (+1)
Isocitrate dehydrogenase [NAD] subunit, mitochondrial
F1RKU0_PIG
Branched-chain-amino-acid aminotransferase BCAT2
F1RL80_PIG
Uncharacterized protein COX6B
F1RLH7_PIG
Uncharacterized protein (Fragment) DAP3
F1RLM4_PIG (+1)
Uncharacterized protein (Fragment) TOMM40
F1RM44_PIG (+1)
Uncharacterized protein DIABLO
F1RNS2_PIG
Cytochrome b-c1 complex subunit Rieske, mitochondrial
F1RNZ1_PIG
Uncharacterized protein F1RP22
F1RP22_PIG
Uncharacterized protein (Fragment) CLYBL
F1RP25_PIG
NAD(P)H-hydrate epimerase
F1RP34_PIG
Uncharacterized protein LOC100620271
F1RPD2_PIG
Uncharacterized protein LOC100620271
F1RPD4_PIG
Glycerol-3-phosphate dehydrogenase MGPD
F1RPU0_PIG
Uncharacterized protein MPC2
F1RPU8_PIG
Uncharacterized protein COX7A2
F1RQI1_PIG
Uncharacterized protein PRDX5
F1RQP0_PIG
Uncharacterized protein LOC100515705
F1RQS8_PIG
Uncharacterized protein MRPL49
F1RQV0_PIG
Uncharacterized protein MRPL14
F1RQV7_PIG
F1RIX8
F1RJE4
F1RJH2
F1RJH2_PIG
F1RJM8
F1RJN1
F1RK10
F1RK45
F1RK50
F1RK59
F1RKQ9
F1RKU0
F1RL80
F1RLH7
F1RLM4
F1RM44
F1RNS2
F1RNZ1
F1RP22
F1RP25
F1RP34
F1RPD2
F1RPD4
F1RPU0
F1RPU8
F1RQI1
F1RQP0
F1RQS8
F1RQV0
F1RQV7
Uncharacterized protein CRAT
F1RR45_PIG
Uncharacterized protein ENDOG
F1RR64_PIG
Uncharacterized protein SEPT4
F1RRN6_PIG (+1)
Uncharacterized protein TMEM65
F1RRP8_PIG
Uncharacterized protein NDUFB9
F1RRP9_PIG (+1)
Uncharacterized protein (Fragment) PTGES2
F1RRY6_PIG
Uncharacterized protein PTRH1
F1RS13_PIG (+1)
78 kDa glucose-regulated protein
F1RS36_PIG (+1)
Uncharacterized protein ACSL1
F1RSZ3_PIG
Uncharacterized protein LOC100519752
F1RT47_PIG
Uncharacterized protein ACSF2
F1RT96_PIG
Uncharacterized protein AIFM1
F1RTH3_PIG
Uncharacterized protein MRPL11
F1RU54_PIG
Uncharacterized protein ACOT13
F1RUE0_PIG
Uncharacterized protein ALDH5A1
F1RUE3_PIG
Uncharacterized protein (Fragment) ECHDC3
F1RUP0_PIG
Uncharacterized protein MRPS10
F1RUU2_PIG
Uncharacterized protein MSRB2
F1RVI8_PIG
Uncharacterized protein NDUFV1
F1RVN1_PIG
Uncharacterized protein MRPS7
F1RVX4_PIG
Uncharacterized protein DSP
Electron transfer flavoprotein-ubiquinone oxidoreductase,
mitochondrial
F1RW75_PIG
Uncharacterized protein LOC100157053
F1RWL7_PIG
Uncharacterized protein NDUFB11
F1RWV4_PIG
Uncharacterized protein UBA1
F1RWX8_PIG (+1)
Uncharacterized protein BPHL
F1RWY7_PIG
Uncharacterized protein ECI2
F1RWZ4_PIG
Uncharacterized protein PROSC
F1RX84_PIG
Uncharacterized protein MRPS28
F1RX97_PIG
F1RR45
F1RR64
F1RRN6
F1RRP8
F1RRP9
F1RRY6
F1RS13
F1RS36
F1RSZ3
F1RT47
F1RT96
F1RTH3
F1RU54
F1RUE0
F1RUE3
F1RUP0
F1RUU2
F1RVI8
F1RVN1
F1RVX4
F1RW75
F1RW89
F1RW89_PIG
F1RWL7
F1RWV4
F1RWX8
F1RWY7
F1RWZ4
F1RX84
F1RX97
Uncharacterized protein RMDN1
F1RXD4_PIG
Uncharacterized protein DECR1
F1RXF3_PIG
Uncharacterized protein SCO2
F1RXT7_PIG
Uncharacterized protein PDP1
F1RY43_PIG
Uncharacterized protein ACSS3
F1RYM4_PIG
Uncharacterized protein (Fragment) MRPL1
F1RYS1_PIG
Uncharacterized protein SLC25A4
F1RZQ6_PIG
Uncharacterized protein BAK1
F1RZR2_PIG
Uncharacterized protein MRPS2
F1S001_PIG
Uncharacterized protein NDUFS6
F1S031_PIG
Uncharacterized protein HRSP12
F1S0M2_PIG
Cytochrome c oxidase subunit 6C COX6C
F1S0P0_PIG
Uncharacterized protein PFDN2
F1S192_PIG (+1)
Uncharacterized protein COA3
F1S1F3_PIG
Uncharacterized protein TIMM8A
F1S1L1_PIG
Ferrochelatase (Fragment) FECH
F1S1X4_PIG
Uncharacterized protein PTRH2
F1S227_PIG
4-trimethylaminobutyraldehyde dehydrogenase
F1S232_PIG
Uncharacterized protein MRPL13
F1S286_PIG
Isocitrate dehydrogenase [NAD] subunit, mitochondrial
F1S297_PIG
Peptidyl-prolyl cis-trans isomerase
F1S2E3_PIG
Uncharacterized protein (Fragment) PDF
F1S391_PIG
Uncharacterized protein CYB5B
F1S393_PIG
Uncharacterized protein F1S3B0
F1S3B0_PIG
Peptidyl-prolyl cis-trans isomerase NIMA interacting 1
F1S3G5_PIG
Uncharacterized protein ALDH6A1
F1S3H1_PIG
Uncharacterized protein (Fragment) COQ6
F1S3H4_PIG
Uncharacterized protein PRDX1
F1S3U9_PIG
Cytochrome b-c1 complex subunit 6
F1S3W0_PIG
Uncharacterized protein PRDX3
F1S418_PIG
F1RXD4
F1RXF3
F1RXT7
F1RY43
F1RYM4
F1RYS1
F1RZQ6
F1RZR2
F1S001
F1S031
F1S0M2
F1S0P0
F1S192
F1S1F3
F1S1L1
F1S1X4
F1S227
F1S232
F1S286
F1S297
F1S2E3
F1S391
F1S393
F1S3B0
F1S3G5
F1S3H1
F1S3H4
F1S3U9
F1S3W0
F1S418
Uncharacterized protein (Fragment) SYNJ2BP
F1S4A6_PIG
Uncharacterized protein COX16
F1S4A8_PIG
Uncharacterized protein (Fragment) CCBL2
F1S4D5_PIG
NADH-cytochrome b5 reductase
F1S4N2_PIG
Uncharacterized protein (Fragment) COX7A2L
F1S4V0_PIG
Uncharacterized protein DBT
F1S563_PIG
Uncharacterized protein LRPPRC
F1S5J1_PIG (+1)
Uncharacterized protein IBA57 PE=3 SV=1
F1S5S1_PIG
Uncharacterized protein SARS
F1S5Z3_PIG
ATP synthase subunit delta, mitochondrial
F1S6Q7_PIG
Uncharacterized protein CPT2
F1S764_PIG
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial
F1S897_PIG
Uncharacterized protein MRPS26
F1S8A5_PIG
Uncharacterized protein MAVS
F1S8C6_PIG (+1)
Uncharacterized protein APEX1
F1S8H5_PIG
Uncharacterized protein ADCK3
F1S8Q4_PIG
Uncharacterized protein MRPL43
F1S8U4_PIG
Uncharacterized protein HOGA1
F1S8X9_PIG
Mitochondrial amidoxime reducing component 2
F1S9I9_PIG
Uncharacterized protein LOC100739845
F1S9K1_PIG
Uncharacterized protein ECSIT
F1SA28_PIG
Uncharacterized protein (Fragment) LOC100517634
F1SA62_PIG
Mitochondrial import inner membrane translocase subunit
F1SA66_PIG
Uncharacterized protein ECHS1
F1SAC1_PIG
Dihydrolipoyl dehydrogenase
F1SAF0_PIG
Uncharacterized protein ATP5L
F1SAK6_PIG
Acetyl-coenzyme A synthetase
F1SAS2_PIG
Uncharacterized protein (Fragment) LOC100737714
F1SAZ6_PIG
Superoxide dismutase SOD2
F1SB60_PIG
Uncharacterized protein MRPL18
F1SB64_PIG
F1S4A6
F1S4A8
F1S4D5
F1S4N2
F1S4V0
F1S563
F1S5J1
F1S5S1
F1S5Z3
F1S6Q7
F1S764
F1S897
F1S8A5
F1S8C6
F1S8H5
F1S8Q4
F1S8U4
F1S8X9
F1S9I9
F1S9K1
F1SA28
F1SA62
F1SA66
F1SAC1
F1SAF0
F1SAK6
F1SAS2
F1SAZ6
F1SB60
F1SB64
Uncharacterized protein NDUFAF5
F1SBJ3_PIG
Uncharacterized protein ATP5F1
Solute carrier family 16, member 1 (Monocarboxylic acid
transporter 1)
F1SBN7_PIG
ATP-dependent Clp protease proteolytic subunit
F1SBT2_PIG
Lon protease homolog, mitochondrial LONP1
F1SBU7_PIG
Uncharacterized protein C19orf70
F1SBU8_PIG
F1SBJ3
F1SBN7
F1SBQ5
F1SBQ5_PIG
Uncharacterized protein (Fragment) NDUFB7
F1SCH1_PIG
Uncharacterized protein RDH14
F1SCT9_PIG (+1)
cAMP-dependent protein kinase catalytic subunit alpha
F1SD45_PIG
Uncharacterized protein NDUFB1
F1SD73_PIG
Uncharacterized protein (Fragment) LOC100739748
F1SD94_PIG
Uncharacterized protein GADD45GIP1
F1SD95_PIG
Uncharacterized protein ALDH3A2
F1SDC7_PIG
Uncharacterized protein HADHB
F1SDN2_PIG
Uncharacterized protein OAT
F1SDP3_PIG
Uncharacterized protein TIMM23
F1SDW3_PIG (+1)
Uncharacterized protein TGM2
F1SDX6_PIG
Uncharacterized protein VDAC1P5
F1SE26_PIG
Uncharacterized protein OCIAD1
F1SE83_PIG
Uncharacterized protein (Fragment) ACADSB
F1SED0_PIG
Glutamate dehydrogenase 1, mitochondrial
F1SEN2_PIG
Uncharacterized protein GHITM
F1SEQ3_PIG
Uncharacterized protein FAM213A PE=4 SV=1
F1SEQ7_PIG
Uncharacterized protein (Fragment) SLC25A13
F1SF87_PIG
Uncharacterized protein LYRM5
F1SFJ7_PIG
Succinyl-CoA ligase subunit beta
F1SFR6_PIG (+1)
Uncharacterized protein DNAJC19 PE=4 SV=2
F1SGA9_PIG
Uncharacterized protein NDUFB5
F1SGC6_PIG
Uncharacterized protein MRPL47
F1SGC7_PIG
F1SBT2
F1SBU7
F1SBU8
F1SCH1
F1SCT9
F1SD45
F1SD73
F1SD94
F1SD95
F1SDC7
F1SDN2
F1SDP3
F1SDW3
F1SDX6
F1SE26
F1SE83
F1SED0
F1SEN2
F1SEQ3
F1SEQ7
F1SF87
F1SFJ7
F1SFR6
F1SGA9
F1SGC6
F1SGC7
Uncharacterized protein PDHB
F1SGH5_PIG
Catalase
F1SGS9_PIG
Uncharacterized protein PDHX
F1SGT3_PIG
Uncharacterized protein (Fragment) NDUFS1
F1SHD7_PIG
Pyruvate kinase (Fragment) PKM
F1SHL9_PIG
Uncharacterized protein BCL2L13
F1SHR2_PIG
Uncharacterized protein (Fragment) LOC100516841
F1SHU0_PIG
Uncharacterized protein (Fragment) ATP5S
F1SHX8_PIG
Uncharacterized protein NDUFB3
F1SI50_PIG
Uncharacterized protein LOC100522576
F1SI71_PIG (+1)
Uncharacterized protein MYBPC3
F1SID7_PIG
Uncharacterized protein MTCH2
F1SIE0_PIG
Uncharacterized protein NDUFS3
F1SIF2_PIG
Uncharacterized protein STOML2
F1SIH5_PIG
Uncharacterized protein NDUFA10
F1SIS9_PIG
Uncharacterized protein COX5A
F1SJ34_PIG
NADH-cytochrome b5 reductase 3 (Fragment)
F1SJQ5_PIG (+1)
Uncharacterized protein EXOG
F1SJT1_PIG
Uncharacterized protein ETFA
Isocitrate dehydrogenase [NADP], mitochondrial
(Fragment)
F1SJX1_PIG
GTP:AMP phosphotransferase AK3, mitochondrial
F1SK45_PIG
Uncharacterized protein PLGRKT
F1SK49_PIG
Uncharacterized protein NDUFAF3
F1SKI6_PIG
Sulfurtransferase
F1SKL2_PIG
Uncharacterized protein UQCRC1
F1SKM0_PIG
Uncharacterized protein
F1SKY2_PIG
Uncharacterized protein LOC100524622
F1SL07_PIG
Uncharacterized protein MRPS22
F1SL55_PIG
Uncharacterized protein (Fragment) TOMM22
F1SLC2_PIG
F1SGH5
F1SGS9
F1SGT3
F1SHD7
F1SHL9
F1SHR2
F1SHU0
F1SHX8
F1SI50
F1SI71
F1SID7
F1SIE0
F1SIF2
F1SIH5
F1SIS9
F1SJ34
F1SJQ5
F1SJT1
F1SJX1
F1SK00
F1SK00_PIG (+1)
F1SK45
F1SK49
F1SKI6
F1SKL2
F1SKM0
F1SKY2
F1SL07
F1SL55
F1SLC2
Uncharacterized protein SPR
F1SLF0_PIG
Uncharacterized protein CCT7
F1SLF6_PIG
Uncharacterized protein (Fragment) NDUFS4
F1SLQ3_PIG
Uncharacterized protein MRRF
F1SLQ7_PIG
Uncharacterized protein NDUFA8
F1SLR1_PIG
Uncharacterized protein NDUFA5
F1SLY2_PIG
Uncharacterized protein NDUFV2
Succinate dehydrogenase [ubiquinone] cytochrome b small
subunit, mitochondrial
Acetyltransferase component of pyruvate dehydrogenase
complex
F1SM98_PIG
Uncharacterized protein ATP5H
F1SMF9_PIG
Uncharacterized protein (Fragment) LOC100526144
F1SMG3_PIG
Uncharacterized protein (Fragment) EFHD1
F1SMT0_PIG
Uncharacterized protein HSPE1 PE=3 SV=1
F1SMZ6_PIG
Uncharacterized protein COQ10B
F1SMZ8_PIG
Uncharacterized protein HSDL2
F1SNA8_PIG
Uncharacterized protein CHCHD3
F1SNF6_PIG
Uncharacterized protein LOC100622200
F1SNL5_PIG
Uncharacterized protein (Fragment) NDUFA12
F1SQP4_PIG
Uncharacterized protein (Fragment) SLC25A3
F1SQT3_PIG
Aconitate hydratase, mitochondrial (Fragment)
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex
subunit 6
F1SRC5_PIG
Single-stranded DNA-binding protein SSBP1
F1SRQ7_PIG
Uncharacterized protein MRPL46
F1SRT0_PIG
Uncharacterized protein GSTK1
F1SRV4_PIG
Uncharacterized protein SCO1
F1SS60_PIG
Uncharacterized protein LOC100515636
F1SSH8_PIG
Uncharacterized protein TIMM9
F1SSK4_PIG
Uncharacterized protein IVD
F1SLF0
F1SLF6
F1SLQ3
F1SLQ7
F1SLR1
F1SLY2
F1SM98
F1SMA9
F1SMA9_PIG
F1SMB2
F1SMB2_PIG
F1SMF9
F1SMG3
F1SMT0
F1SMZ6
F1SMZ8
F1SNA8
F1SNF6
F1SNL5
F1SQP4
F1SQT3
F1SRC5
F1SRG2
F1SRG2_PIG
F1SSR4_PIG
F1SRQ7
F1SRT0
F1SRV4
F1SS60
F1SSH8
F1SSK4
F1SSR4
Uncharacterized protein NDUFAF1
F1SSV5_PIG
Uncharacterized protein HINT2
F1STB2_PIG
Uncharacterized protein MECR
F1STL4_PIG
Uncharacterized protein (Fragment) ME3
F1STS4_PIG
NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2
F1STY1_PIG
Uncharacterized protein CHCHD1
F1SU49_PIG
Uncharacterized protein LOC100522130
F1SU52_PIG
Uncharacterized protein (Fragment) HK1
F1SUF2_PIG
Uncharacterized protein NDUFS5
F1SV23_PIG
Uncharacterized protein (Fragment) TOMM20
F2Z4X6_PIG (+1)
Mitochondrial fission 1 protein
FIS1_HUMAN
Fumarate hydratase, mitochondrial
FUMH_PIG
FUN14 domain-containing protein 2 FUNDC2
FUND2_PIG
Guanine nucleotide-binding protein subunit beta-2-like 1
GBLP_HUMAN
Glutaryl-CoA dehydrogenase, mitochondrial (Fragment)
Phospholipid hydroperoxide glutathione peroxidase,
mitochondrial
GCDH_PIG
Stress-70 protein, mitochondrial
GRP75_HUMAN
F1STB2
F1STL4
F1STS4
F1STY1
F1SU49
F1SU52
F1SUF2
F1SV23
F2Z4X6
Q9Y3D6
XP_003362140
P10173
Q864V5
P63244
P81140
P36968
GPX4_PIG
Glutathione S-transferase P GSTP1
GSTP1_PIG
3-hydroxyacyl-CoA dehydrogenase type-2
HCD2_HUMAN
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
HCDH_PIG
Hydroxyacid-oxoacid transhydrogenase, mitochondrial
HOT_HUMAN
Heat shock protein HSP 90-beta
F1SSV5
HS90B_HUMAN
Serine protease HTRA2, mitochondrial
HTRA2_HUMAN
Hexokinase-1
HXK1_HUMAN
Uncharacterized protein I3L614
I3L614_PIG
Uncharacterized protein MRPS25
I3L6Z8_PIG
Uncharacterized protein I3L7T8
I3L7T8_PIG
Uncharacterized protein TPP1
I3L812_PIG
Uncharacterized protein (Fragment) SLC25A12
I3L8T2_PIG
P38646
XP_005661752
P80031
Q99714
XP_003135174
P00348
Q8IWW8
P08238
O43464
P19367
I3L614
I3L6Z8
I3L7T8
I3L812
I3L8T2
XP_003125651
NP_001231362
XP_005674479
NP_001230113
Uncharacterized protein NDUFAF2
I3L8Y0_PIG
Uncharacterized protein (Fragment)
I3L9E4_PIG
Uncharacterized protein (Fragment) BSG
I3L9F1_PIG
Uncharacterized protein NDUFAF4
I3L9T7_PIG
Uncharacterized protein (Fragment)
I3LAI1_PIG
Uncharacterized protein (Fragment) TIMM50
I3LC09_PIG
Uncharacterized protein LOC100525869
I3LCI0_PIG
Pyruvate dehydrogenase E1 component subunit alpha
I3LCI2_PIG
Uncharacterized protein FIS1
I3LD01_PIG
Uncharacterized protein SIRT5
I3LD45_PIG
Uncharacterized protein (Fragment) COQ3
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit,
mitochondrial
I3LD55_PIG
Uncharacterized protein NDUFB10
I3LDC3_PIG
Isocitrate dehydrogenase [NADP] cytoplasmic (Fragment)
I3LDC7_PIG
Uncharacterized protein (Fragment) PGAM5
I3LE16_PIG
Uncharacterized protein HSD17B4
I3LEF8_PIG
Uncharacterized protein (Fragment) MRPS6
I3LEJ9_PIG
Uncharacterized protein STRAP
I3LEQ7_PIG
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial
I3LER5_PIG
Uncharacterized protein BCS1L
I3LFK0_PIG
Uncharacterized protein (Fragment)
I3LG46_PIG
Uncharacterized protein NDUFA11
I3LGM4_PIG
Uncharacterized protein (Fragment) NDUFS7
I3LHL4_PIG
Uncharacterized protein (Fragment)
I3LHS7_PIG
Uncharacterized protein (Fragment) MYO1C
I3LIL4_PIG
Uncharacterized protein HMGCL
I3LIL5_PIG
I3L8Y0
I3L9E4
I3L9F1
I3L9T7
I3LAI1
I3LC09
I3LCI0
I3LCI2
I3LD01
I3LD45
I3LD55
I3LDC1
I3LDC1_PIG
Uncharacterized protein (Fragment) CISD3
I3LIT8_PIG (+1)
Uncharacterized protein LOC100623793
I3LJ05_PIG
Uncharacterized protein ECH1
I3LJJ4_PIG
I3LDC3
I3LDC7
I3LE16
I3LEF8
I3LEJ9
I3LEQ7
I3LER5
I3LFK0
I3LG46
I3LGM4
I3LHL4
I3LHS7
I3LIL4
I3LIL5
I3LIT8
I3LJ05
I3LJJ4
Uncharacterized protein TMEM126A
I3LJK4_PIG
Uncharacterized protein HSPB7
I3LJU7_PIG
Uncharacterized protein (Fragment) ACO1
I3LJW4_PIG
Uncharacterized protein (Fragment) ACSF3
I3LK72_PIG
Uncharacterized protein FAM162A
I3LKD2_PIG
Uncharacterized protein (Fragment) LOC100520636
I3LLE3_PIG
Uncharacterized protein DNAJA3
I3LLG4_PIG
Uncharacterized protein ECI1
I3LLH8_PIG
Uncharacterized protein
I3LLI0_PIG
Uncharacterized protein ETHE1
I3LLM9_PIG
Uncharacterized protein SAMM50
I3LLW3_PIG
Uncharacterized protein LOC100512831
I3LLY6_PIG
Uncharacterized protein PPA2
I3LM66_PIG
Uncharacterized protein (Fragment) ABHD10
I3LMP2_PIG
Uncharacterized protein POLDIP2
I3LMX3_PIG (+1)
Uncharacterized protein (Fragment) ALDH4A1
I3LNB4_PIG
Uncharacterized protein ACAT1
I3LP02_PIG
Malate dehydrogenase
I3LP41_PIG (+1)
Uncharacterized protein TMEM70
I3LPM1_PIG
Fumarate hydratase, mitochondrial
I3LPP1_PIG
Uncharacterized protein NDUFB4
I3LPW0_PIG
Uncharacterized protein PHB2
I3LQN4_PIG
Uncharacterized protein MRPL9
I3LR45_PIG
Uncharacterized protein (Fragment) NDUFV3
I3LRR4_PIG
ATP-dependent (S)-NAD(P)H-hydrate dehydratase
I3LS60_PIG
Uncharacterized protein TIMM13
I3LS73_PIG (+1)
Adenylate kinase 2, mitochondrial
I3LSI3_PIG
Uncharacterized protein (Fragment) IMMT
I3LSM7_PIG
Uncharacterized protein MRPL12
I3LSY1_PIG
Uncharacterized protein MCCC1
I3LT90_PIG
I3LJK4
I3LJU7
I3LJW4
I3LK72
I3LKD2
I3LLE3
I3LLG4
I3LLH8
I3LLI0
I3LLM9
I3LLW3
I3LLY6
I3LM66
I3LMP2
I3LMX3
I3LNB4
I3LP02
I3LP41
I3LPM1
I3LPP1
I3LPW0
I3LQN4
I3LR45
I3LRR4
I3LS60
I3LS73
I3LSI3
I3LSM7
I3LSY1
I3LT90
Uncharacterized protein (Fragment) I3LTC0
I3LTC0_PIG
Cytochrome c oxidase subunit 6A, mitochondrial
I3LTV6_PIG
Uncharacterized protein (Fragment) IARS2
I3LUE8_PIG
Uncharacterized protein (Fragment) ACAD9
I3LUR5_PIG
Uncharacterized protein LOC100516656
I3LUZ8_PIG
GrpE protein homolog LOC100622145
Isocitrate dehydrogenase [NAD] subunit gamma,
mitochondrial (Fragments)
I3LVG4_PIG
Translation initiation factor IF-2, mitochondrial
IF2M_HUMAN-DECOY
Uncharacterized protein ADHFE1
K7GMB9_PIG
Uncharacterized protein ILF3
K7GP99_PIG
cAMP-dependent protein kinase catalytic subunit beta
KAPCB_HUMAN
Creatine kinase M-type
KCRM_PIG
L-lactate dehydrogenase A chain
Methylmalonate-semialdehyde dehydrogenase [acylating],
mitochondrial
LDHA_PIG
Phosphate carrier protein, mitochondrial
I3LUE8
I3LUR5
I3LUZ8
I3LVG4
P41566
P46199
K7GMB9
XP_003354867
K7GP99
P22694
P05383.3
Q5XLD3
P00339
Q02252
MMSA_HUMAN
MPCP_HUMAN
MTX2_PIG
Methylmalonyl-CoA mutase, mitochondrial
MUTA_PIG
Myomesin-2
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3,
mitochondrial
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4,
mitochondrial
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8,
mitochondrial
MYOM2_HUMAN
XP_001929208
Q00325
NP_001157984
Q2L969
Q8MI68
P54296
XP_005657583
O75489
NDUS3_HUMAN
NP_001230725.1
O43181
NDUS4_HUMAN
AET25525.1
O00217
NDUS8_HUMAN
NFU1_HUMAN
Protein NipSnap homolog 2
NIPS2_HUMAN
Omega-amidase NIT2
NIT2_HUMAN
NAD(P) transhydrogenase, mitochondrial
I3LTV6
IDH3G_PIG
Metaxin-2 MTX2
NFU1 iron-sulfur cluster scaffold homolog, mitochondrial
I3LTC0
NNTM_HUMAN
NADH-ubiquinone oxidoreductase chain 1
NU1M_PIG
OCIA domain-containing protein 1
OCAD1_HUMAN
2-oxoglutarate dehydrogenase, mitochondrial
ODO1_HUMAN
XP_005660672
Q9UMS0
O75323
Q9NQR4
Q13423
XP_005662555
XP_003359199
NP_001231271
XP_003133978
O79874
Q9NX40
Q02218
XP_003482426
XP_003134939
Dihydrolipoyllysine-residue succinyltransferase component
of 2-oxoglutarate dehydrogenase complex, mitochondrial
Pyruvate dehydrogenase E1 component subunit alpha,
testis-specific form, mitochondrial
Dynamin-like 120 kDa protein, mitochondrial
Protein DJ-1
Q9N0F1
ODO2_PIG
P29803
ODPAT_HUMAN
OPA1_HUMAN
PARK7_HUMAN
Propionyl-CoA carboxylase alpha chain, mitochondrial
PCCA_HUMAN
Propionyl-CoA carboxylase beta chain, mitochondrial
Pyruvate dehydrogenase phosphatase regulatory subunit,
mitochondrial
PCCB_PIG
Prohibitin
PHB_HUMAN
Protein phosphatase 1E
PPM1E_HUMAN
Q99623
XP_003131608
NP_001230485
NP_999531.1
PP2AB_HUMAN
PSB3_HUMAN
PTRF_HUMAN
Q2EN80_PIG
Mitochondrial creatine kinase 2
Q2HYU1_PIG
Cytochrome c oxidase subunit 2
Q69GF7_PIG
Cytochrome b-c1 complex subunit 2, mitochondrial
QCR2_HUMAN
Cytochrome b-c1 complex subunit 7
QCR7_HUMAN
RL10A_HUMAN
RL35A_HUMAN
39S ribosomal protein L12, mitochondrial
RM12_HUMAN
39S ribosomal protein L22, mitochondrial
RM22_HUMAN
40S ribosomal protein S19
XP_005653301
P35232
P62714
Q2EN79_PIG
40S ribosomal protein S14
XP_005668570
P79384
PP2AA_HUMAN
NADH dehydrogenase 1 beta subcomplex 6 LOC733605
60S ribosomal protein L35a
NP_001072131
P67775
Ubiquinol-cytochrome c reductase complex
60S ribosomal protein L10a
P05165
XP_003132646
Q8NCN5
PHB2_HUMAN
Polymerase I and transcript release factor
Q99497
PDPR_HUMAN
Prohibitin-2
Serine/threonine-protein phosphatase 2A catalytic subunit
alpha isoform
Serine/threonine-protein phosphatase 2A catalytic subunit
beta isoform
Proteasome subunit beta type-3
XP_003360292.2
O60313
RS14_HUMAN
RS19_HUMAN
28S ribosomal protein S28, mitochondrial
RT28_HUMAN
Reticulon-4-interacting protein 1, mitochondrial
RT4I1_HUMAN
NP_999531
Q8WY54
P49720
Q6NZI2
XP_005669053
NP_001138374
XP_005652497.1
Q2EN79
Q2EN80
Q2HYU1
Q69GF7
P22695
P14927
P62906
P18077
P52815
Q9NWU5
P62263
P39019
Q9Y2Q9
Q8WWV3
XP_003124603.2
NP_001172101
XP_005665965.1
XP_003357274.1
XP_003361696.2
4V19_W
4W23_O
XP_003127229
NP_001172097.1
XP_003121373.1
Sorting and assembly machinery component 50 homolog
Succinyl-CoA:3-ketoacid coenzyme A transferase 1,
mitochondrial
Succinate dehydrogenase [ubiquinone] flavoprotein
subunit, mitochondrial
SAM50_HUMAN
Staphylococcal nuclease domain-containing protein 1
SND1_HUMAN
Q9Y512
XP_005658384.1
Q29551
SCOT1_PIG
Q0QF01
SDHA_PIG
Superoxide dismutase [Cu-Zn]
Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha,
mitochondrial
SODC_PIG
Transcription factor A, mitochondrial
TFAM_PIG
Acetyl-CoA acetyltransferase, mitochondrial
Mitochondrial import inner membrane translocase subunit
Tim8
THIL_HUMAN
Mitochondrial import receptor subunit TOM7 homolog
TOM7_PIG
Mitochondrial import receptor subunit TOM70
TOM70_HUMAN
Q7KZF4
XP_005673244.1
P04178
O19069
SUCA_PIG
Q5D144
P24752
XP_005667358.1
Q9Y5J9
TIM8B_HUMAN
Voltage-dependent anion-selective channel protein 1
VDAC1_PIG
Voltage-dependent anion-selective channel protein 2
VDAC2_HUMAN (+1)
XP_003129897.3
A1XQS2
O94826
XP_005654126.1
Q9MZ16
P45880
NP_999534.1
Supplemental Table 4. Mitochondrial proteins with significant changes in expression 3 and 15 days after I/R.
Quantitative Value
Identified Proteins
Uniprot
accession ID
Molecular
Weight
Control
3 I/R
15 I/R
3 I/R vs Control
15 I/R vs Control
Fold
Change
Dunnet
ANOVA
Fold
Change
Dunnet
ANOVA
Estradiol 17-beta-dehydrogenase 8
A5D9P1_PIG
27 kDa
1.0 ± 1.7
4.0 ± 1.7
3.3 ± 2.2
4.0
0.036
3.3
0.088
Aspartate aminotransferase, mitochondrial
AATM_PIG
47 kDa
108.5 ± 29.6
152.2 ± 15.4
127.5 ± 16.3
1.4
0.010
1.2
0.259
Long-chain specific acyl-CoA
dehydrogenase, mitochondrial
ACADL_PIG
48 kDa
58.5 ± 16.1
87.8 ± 11.2
64.3 ± 9.8
1.5
0.004
1.1
0.655
ADP/ATP translocase 3
ADT3_PIG
33 kDa
28.0 ± 30.9
66.8 ± 7.9
49.2 ± 24.4
2.4
0.033
1.8
0.249
ATP synthase subunit e, mitochondrial
ATP5I_PIG
8 kDa
61.7 ± 35.0
153.0 ± 24.9
118.5 ± 44.8
2.5
0.002
1.9
0.032
ATP synthase subunit a MT-ATP6
ATP6_PIG
25 kDa
3.8 ± 3.1
2.4 ± 5.4
13.2 ± 2.1
0.6
0.749
3.5
0.001
ATP synthase subunit alpha, mitochondrial
ATPA_PIG
60 kDa
909.5 ± 220.1
1231.4 ± 64.7
1126.7 ± 221.7
1.4
0.026
1.2
0.119
Methylglutaconyl-CoA hydratase,
mitochondrial
AUHM_HUMAN
36 kDa
2.3 ± 1.9
6.6 ± 1.9
2.5 ± 1.8
2.9
0.004
1.1
0.983
Brain protein 44
BR44_HUMAN
14 kDa
4.1 ± 1.7
17.4 ± 10.0
19.0 ± 7.4
10.2
0.006
11.2
0.002
Brain protein 44-like protein
BR44L_HUMAN
14 kDa
6.3 ± 4.5
12.0 ± 3.8
10.2 ± 3.4
1.9
0.035
1.6
0.132
Succinate dehydrogenase cytochrome b560
subunit, mitochondrial
C560_PIG
19 kDa
6.0 ± 2.1
11.4 ± 0.9
8.2 ± 5.0
1.9
0.030
1.4
0.435
10 kDa heat shock protein, mitochondrial
CH10_HUMAN
11 kDa
14.3 ± 2.1
27.8 ± 7.7
14.8 ± 8.4
1.9
0.008
1.0
0.988
CDGSH iron-sulfur domain-containing protein
3, mitochondrial
CISD3_HUMAN
14 kDa
10.8 ± 3.3
7.6 ± 2.6
5.3 ± 2.7
0.7
0.155
0.5
0.011
Citrate synthase, mitochondrial
CISY_PIG
52 kDa
54.8 ± 15.4
74.2 ± 7.7
69.8 ± 5.2
1.4
0.017
1.3
0.050
Clusterin CLU
CLUS_PIG
52 kDa
1.0 ± 1.1
8.0 ± 6.2
3.5 ± 2.7
8.0
0.014
3.5
0.424
Hexaprenyldihydroxybenzoate
methyltransferase, mitochondrial
COQ3_HUMAN
41 kDa
9.3 ± 2.3
12.4 ± 1.8
6.3 ± 2.1
1.3
0.055
0.7
0.049
Ubiquinone biosynthesis protein COQ7
homolog
COQ7_HUMAN
24 kDa
3.2 ± 1.0
5.4 ± 1.5
2.0 ± 1.7
1.7
0.038
0.6
0.293
Dehydrogenase/reductase SDR family
member 4
DHRS4_PIG
30 kDa
60.7 ± 15.7
76.0 ± 6.5
77.8 ± 7.2
1.3
0.064
1.3
0.030
Elongation factor 1-beta
EF1B_HUMAN
25 kDa
1.5 ± 1.2
4.6 ± 0.9
7.7 ± 2.8
3.1
0.031
5.1
0.000
Electron transfer flavoprotein subunit beta
ETFB_PIG
28 kDa
49.2 ± 9.7
64.6 ± 10.7
48.8 ± 5.3
1.3
0.021
1.0
0.997
Uncharacterized protein MTFP1
F1RFC8_PIG
18 kDa
9.0 ± 3.0
8.4 ± 3.0
5.0 ± 1.1
0.9
0.894
0.6
0.027
NADH dehydrogenase [ubiquinone] 1 alpha
subcomplex subunit 2
F1RGE3_PIG
11 kDa
34.3 ± 5.4
42.4 ± 4.8
29.0 ± 3.5
1.2
0.022
0.8
0.115
Uncharacterized protein COA6
F1RGW3_PIG
15 kDa
0.0 ± 0.0
1.4 ± 1.3
0.3 ± 0.8
1.4
0.034
0.3
0.738
Uncharacterized protein MRPL24
F1RHJ1_PIG
25 kDa
0.0 ± 0.0
1.4 ± 1.3
0.3 ± 0.8
1.4
0.034
0.3
0.738
Uncharacterized protein GLOD4
F1RHJ9_PIG
54 kDa
1.8 ± 1.6
5.4 ± 2.6
1.0 ± 1.7
3.0
0.018
0.6
0.693
Uncharacterized protein LOC100525876
F1RJE4_PIG
67 kDa
6.3 ± 4.1
12.2 ± 3.3
9.3 ± 2.1
1.9
0.019
1.5
0.229
Uncharacterized protein TRAP1
F1RK45_PIG
80 kDa
3.8 ± 2.5
9.8 ± 2.9
6.2 ± 2.5
2.6
0.004
1.6
0.241
Cytochrome b-c1 complex subunit Rieske,
mitochondrial
F1RNZ1_PIG
29 kDa
59.7 ± 9.6
84.6 ± 14.9
86.0 ± 24.2
1.4
0.061
1.4
0.038
Uncharacterized protein (Fragment) CLYBL
F1RP25_PIG
33 kDa
2.2 ± 1.8
5.4 ± 0.9
2.5 ± 1.4
2.5
0.005
1.1
0.894
Uncharacterized protein LOC100620271
F1RPD2_PIG
49 kDa
136.5 ± 29.1
163.6 ± 27.9
192.0 ± 26.6
1.2
0.224
1.4
0.007
Uncharacterized protein MRPL11
F1RU54_PIG
21 kDa
2.7 ± 2.6
5.8 ± 1.5
1.0 ± 1.7
2.1
0.040
0.4
0.287
Uncharacterized protein (Fragment)
ECHDC3
F1RUP0_PIG
32 kDa
0.0 ± 0.0
2.2 ± 0.4
0.0 ± 0.0
2.2
0.000
0.0
1.000
Uncharacterized protein LOC100157053
F1RWL7_PIG
22 kDa
17.2 ± 7.0
17.0 ± 2.3
9.3 ± 5.0
1.0
0.998
0.5
0.041
Uncharacterized protein PROSC
F1RX84_PIG
30 kDa
1.2 ± 1.3
3.2 ± 0.8
2.2 ± 1.2
2.7
0.021
1.8
0.260
Uncharacterized protein SCO2
F1RXT7_PIG
30 kDa
2.2 ± 1.7
0.0 ± 0.0
0.8 ± 1.3
0.0
0.029
0.4
0.169
Uncharacterized protein (Fragment) MRPL1
F1RYS1_PIG
31 kDa
1.0 ± 1.7
4.0 ± 0.7
1.8 ± 1.0
4.0
0.002
1.8
0.414
Uncharacterized protein SLC25A4
F1RZQ6_PIG
33 kDa
107.7 ± 12.7
131.0 ± 14.3
109.5 ± 15.6
1.2
0.031
1.0
0.965
Uncharacterized protein HRSP12
F1S0M2_PIG
14 kDa
0.5 ± 1.2
2.8 ± 1.9
1.2 ± 1.3
5.6
0.042
2.4
0.667
Peptidyl-prolyl cis-trans isomerase
F1S2E3_PIG
22 kDa
10.5 ± 2.9
20.4 ± 3.5
14.8 ± 5.9
1.9
0.004
1.4
0.189
Uncharacterized protein (Fragment) COQ6
F1S3H4_PIG
51 kDa
21.8 ± 6.9
20.4 ± 3.3
14.7 ± 2.6
0.9
0.838
0.7
0.036
Uncharacterized protein (Fragment)
COX7A2L
F1S4V0_PIG
13 kDa
5.5 ± 3.3
0.0 ± 0.0
1.7 ± 2.9
0.0
0.007
0.3
0.042
ATP synthase subunit delta, mitochondrial
F1S6Q7_PIG
17 kDa
11.8 ± 2.6
29.6 ± 16.7
23.3 ± 5.6
2.5
0.017
2.0
0.104
Uncharacterized protein APEX1
F1S8H5_PIG
35 kDa
2.8 ± 2.6
0.6 ± 1.3
0.0 ± 0.0
0.2
0.084
0.0
0.021
Uncharacterized protein ECHS1
F1SAC1_PIG
31 kDa
41.5 ± 12.5
66.2 ± 8.5
50.0 ± 14.3
1.6
0.009
1.2
0.404
Acetyl-coenzyme A synthetase
F1SAS2_PIG
74 kDa
11.5 ± 2.3
18.6 ± 6.0
6.5 ± 3.1
1.6
0.019
0.6
0.083
Superoxide dismutase SOD2
F1SB60_PIG
25 kDa
40.8 ± 4.6
54.4 ± 7.1
39.7 ± 7.1
1.3
0.006
1.0
0.930
cAMP-dependent protein kinase catalytic
subunit alpha
F1SD45_PIG
41 kDa
7.0 ± 2.2
13.2 ± 2.3
5.8 ± 2.6
1.9
0.001
0.8
0.629
Uncharacterized protein NDUFB1
F1SD73_PIG
7 kDa
7.3 ± 3.0
11.6 ± 1.5
9.8 ± 1.9
1.6
0.015
1.3
0.139
Uncharacterized protein OAT
F1SDP3_PIG
49 kDa
4.7 ± 1.4
14.2 ± 5.1
8.7 ± 3.3
3.0
0.001
1.9
0.115
Uncharacterized protein VDAC1P5
F1SE26_PIG
31 kDa
28.5 ± 4.5
36.8 ± 4.1
34.8 ± 4.7
1.3
0.016
1.2
0.051
Uncharacterized protein (Fragment)
ACADSB
F1SED0_PIG
48 kDa
46.2 ± 13.8
72.0 ± 8.2
64.5 ± 7.1
1.6
0.002
1.4
0.045
Uncharacterized protein FAM213A PE=4
SV=1
F1SEQ7_PIG
26 kDa
1.3 ± 1.5
7.0 ± 3.5
4.2 ± 0.8
5.4
0.001
3.2
0.068
Succinyl-CoA ligase subunit beta
F1SFR6_PIG (+1)
47 kDa
17.5 ± 8.5
34.2 ± 8.4
12.3 ± 4.2
2.0
0.004
0.7
0.386
Catalase
F1SGS9_PIG
60 kDa
5.7 ± 2.7
7.0 ± 2.9
0.7 ± 1.6
1.2
0.581
0.1
0.006
Uncharacterized protein (Fragment) ATP5S
F1SHX8_PIG
24 kDa
3.8 ± 2.5
1.8 ± 2.7
0.0 ± 0.0
0.5
0.216
0.0
0.012
Uncharacterized protein NDUFS3
F1SIF2_PIG
30 kDa
100.8 ± 17.6
134.6 ± 11.8
142.2 ± 24.2
1.3
0.020
1.4
0.004
Uncharacterized protein EXOG
F1SJT1_PIG
41 kDa
1.0 ± 1.1
0.0 ± 0.0
0.0 ± 0.0
0.0
0.044
0.0
0.035
Uncharacterized protein ETFA
F1SJX1_PIG
35 kDa
74.5 ± 20.0
101.8 ± 5.1
82.8 ± 8.6
1.4
0.008
1.1
0.470
Uncharacterized protein SPR
F1SLF0_PIG
29 kDa
6.2 ± 3.3
8.6 ± 2.2
2.2 ± 2.2
1.4
0.258
0.4
0.038
Succinate dehydrogenase [ubiquinone]
cytochrome b small subunit, mitochondrial
F1SMA9_PIG
17 kDa
3.3 ± 3.7
9.2 ± 3.2
3.7 ± 1.9
2.8
0.012
1.1
0.974
Uncharacterized protein HSPE1 PE=3 SV=1
F1SMZ6_PIG
11 kDa
15.7 ± 2.8
27.2 ± 7.6
16.3 ± 9.6
1.7
0.036
1.0
0.982
Single-stranded DNA-binding protein SSBP1
F1SRQ7_PIG
17 kDa
3.0 ± 2.4
11.8 ± 6.2
12.3 ± 7.5
3.9
0.045
4.1
0.026
Uncharacterized protein NDUFAF1
F1SSV5_PIG
30 kDa
0.8 ± 1.3
4.0 ± 1.4
2.5 ± 1.6
5.0
0.006
3.1
0.124
Uncharacterized protein HINT2
F1STB2_PIG
17 kDa
4.5 ± 2.6
11.8 ± 4.9
6.0 ± 2.5
2.6
0.006
1.3
0.671
Uncharacterized protein NDUFS5
F1SV23_PIG
12 kDa
8.2 ± 3.9
21.6 ± 10.9
18.8 ± 10.2
2.6
0.044
2.3
0.096
Fumarate hydratase, mitochondrial
FUMH_PIG
50 kDa
34.3 ± 11.4
59.8 ± 10.3
42.5 ± 4.6
1.7
0.001
1.2
0.248
Glutathione S-transferase P GSTP1
GSTP1_PIG
23 kDa
7.8 ± 2.5
13.2 ± 2.6
5.5 ± 2.2
1.7
0.005
0.7
0.199
Uncharacterized protein MRPS25
I3L6Z8_PIG
11 kDa
0.3 ± 0.8
0.8 ± 1.1
2.5 ± 1.5
2.7
0.747
8.3
0.013
Uncharacterized protein I3L7T8
I3L7T8_PIG
11 kDa
68.8 ± 11.1
90.6 ± 10.1
82.7 ± 8.5
1.3
0.005
1.2
0.055
Uncharacterized protein (Fragment)
I3L9E4_PIG
19 kDa
0.0 ± 0.0
3.4 ± 3.4
0.0 ± 0.0
3.4
0.016
0.0
1.000
Uncharacterized protein (Fragment) BSG
I3L9F1_PIG
24 kDa
10.3 ± 2.9
17.2 ± 3.6
14.0 ± 1.8
1.7
0.002
1.4
0.075
Uncharacterized protein (Fragment)
I3LAI1_PIG
28 kDa
8.3 ± 12.9
48.8 ± 5.3
40.3 ± 11.7
5.9
0.000
4.9
0.000
Uncharacterized protein FIS1
I3LD01_PIG
19 kDa
26.8 ± 4.4
36.8 ± 2.5
30.0 ± 6.3
1.4
0.008
1.1
0.436
Uncharacterized protein (Fragment) COQ3
I3LD55_PIG
38 kDa
9.5 ± 2.0
14.4 ± 4.0
11.3 ± 3.6
1.5
0.047
1.2
0.536
Uncharacterized protein (Fragment)
I3LHS7_PIG
35 kDa
40.8 ± 12.1
60.6 ± 4.5
36.3 ± 4.4
1.5
0.002
0.9
0.543
Uncharacterized protein (Fragment) CISD3
I3LIT8_PIG
13 kDa
12.3 ± 2.7
9.8 ± 3.3
7.2 ± 1.9
0.8
0.229
0.6
0.008
Uncharacterized protein LOC100623793
I3LJ05_PIG
29 kDa
25.0 ± 10.6
28.0 ± 3.9
15.0 ± 1.8
1.1
0.692
0.6
0.041
Uncharacterized protein ECH1
I3LJJ4_PIG
25 kDa
20.2 ± 3.5
30.2 ± 6.3
23.7 ± 3.1
1.5
0.004
1.2
0.313
Uncharacterized protein HSPB7
I3LJU7_PIG
18 kDa
3.7 ± 3.2
2.2 ± 2.3
10.2 ± 3.7
0.6
0.670
2.8
0.006
Uncharacterized protein (Fragment) ACO1
I3LJW4_PIG
99 kDa
4.7 ± 1.6
4.8 ± 1.3
2.3 ± 1.2
1.0
0.982
0.5
0.022
Uncharacterized protein (Fragment) ACSF3
I3LK72_PIG
48 kDa
3.2 ± 1.9
1.0 ± 1.4
0.7 ± 1.0
0.3
0.060
0.2
0.023
Uncharacterized protein (Fragment)
LOC100520636
I3LLE3_PIG
75 kDa
75.0 ± 15.4
105.4 ± 19.7
76.7 ± 10.5
1.4
0.010
1.0
0.975
Uncharacterized protein (Fragment)
ALDH4A1
I3LNB4_PIG
56 kDa
17.2 ± 6.9
29.6 ± 9.2
15.8 ± 4.9
1.7
0.021
0.9
0.926
Fumarate hydratase, mitochondrial
I3LPP1_PIG
50 kDa
37.5 ± 10.1
69.4 ± 11.5
49.3 ± 4.5
1.9
0.000
1.3
0.071
Uncharacterized protein NDUFB4
I3LPW0_PIG
15 kDa
14.5 ± 3.7
36.8 ± 24.9
23.7 ± 10.5
2.5
0.049
1.6
0.481
Uncharacterized protein PHB2
I3LQN4_PIG
33 kDa
70.8 ± 21.6
85.4 ± 11.7
103.3 ± 27.9
1.2
0.464
1.5
0.041
Uncharacterized protein MRPL9
I3LR45_PIG
30 kDa
0.0 ± 0.0
2.2 ± 1.5
1.0 ± 1.1
2.2
0.006
1.0
0.197
Uncharacterized protein (Fragment) IARS2
I3LUE8_PIG
61 kDa
0.0 ± 0.0
4.6 ± 3.1
0.0 ± 0.0
4.6
0.001
0.0
1.000
Uncharacterized protein ADHFE1
K7GMB9_PIG
45 kDa
16.3 ± 4.3
11.0 ± 10.5
0.0 ± 0.0
0.7
0.295
0.0
0.001
cAMP-dependent protein kinase catalytic
subunit beta
KAPCB_HUMAN
41 kDa
0.0 ± 0.0
3.4 ± 4.8
4.5 ± 2.7
3.4
0.149
4.5
0.041
Creatine kinase M-type
KCRM_PIG
43 kDa
164.2 ± 25.4
254.4 ± 15.8
171.7 ± 39.6
1.5
0.000
1.0
0.871
NFU1 iron-sulfur cluster scaffold homolog,
mitochondrial
NFU1_HUMAN
28 kDa
0.0 ± 0.0
1.4 ± 1.3
0.0 ± 0.0
1.4
0.011
0.0
1.000
OCIA domain-containing protein 1
OCAD1_HUMAN
28 kDa
1.3 ± 3.3
9.2 ± 0.8
8.0 ± 1.4
7.1
0.000
6.2
0.000
Proteasome subunit beta type-3
PSB3_HUMAN
23 kDa
1.3 ± 2.2
7.0 ± 3.4
2.7 ± 2.3
5.4
0.006
2.1
0.598
Cytochrome b-c1 complex subunit 2,
mitochondrial
QCR2_HUMAN
48 kDa
35.3 ± 6.7
40.0 ± 9.8
48.3 ± 8.5
1.1
0.568
1.4
0.031
Succinyl-CoA:3-ketoacid coenzyme A
transferase 1, mitochondrial
SCOT1_PIG
56 kDa
34.0 ± 13.6
58.8 ± 7.6
38.8 ± 9.4
1.7
0.003
1.1
0.661
Mitochondrial import receptor subunit TOM70
TOM70_HUMAN
67 kDa
3.7 ± 2.3
7.8 ± 1.5
1.5 ± 2.3
2.1
0.012
0.4
0.174
Voltage-dependent anion-selective channel
protein 1
VDAC1_PIG
31 kDa
72.5 ± 4.3
138.8 ± 50.6
126.7 ± 27.5
1.9
0.007
1.7
0.019
Voltage-dependent anion-selective channel
protein 2
VDAC2_HUMAN
32 kDa
44.3 ± 3.7
53.8 ± 6.6
55.8 ± 8.7
1.2
0.061
1.3
0.018