Nomination Form ------------------------------------------------------------------------------------------------------For Office Use The Nomination for the ……..………………………………….…………… has been received along with all the enclosures on …………………… Signature ------------------------------------------------------------------------------------------------------Nomination for Special Awards We, the members of Association of Biotechnology and Pharmacy, would like to nominate the following person as a candidate for the award of Life time Achievement Award in Biotechnology Life time Achievement Award in Pharmacy Talented Industrial Biotechnologist Award ABAP-Senior Scientist Award √ (Tick which ever is applicable) ------------------------------------------------------------------------------------------------------Name of the Nominee:… Dr.K.S.NAGESH … Address K.S. Nagesh, Door No. 524, 4 /3 Main, E and F Block, Ramkrishnanagar Mysore-570022, Karnataka, India Phone…8050944624………Fax………….. Email [email protected] ------------------------------------------------------------------------------------------------------- We certify the statement made by the candidate and in our opinion he/she is fully qualified for the above award Proposer Name ……………………………………Signature………..………………... Supporter Name……………………………………Signature………………..…..…… A Fellow/Life Member can nominate two members for each award every year BIGRAPHICAL INFORMATION OF NOMINEE 1. Name in full: Dr.K.S.NAGESH 2. Date of Birth & Age: (on the day of application) 23/06/1972 and 43 years 3. Nationality: Indian 4. Present Position/Designation: Lecturer 5. Field of Specialization: 6. Address: Official: Government College, Basavapattana, Arakalgud Taluk Hassan District, Karnataka Residence: Phone: Medicinal plant Tissue culture and Biodiversity Conservation Dr. K.S. Nagesh Door No. 524, 4 /3 Main, E and F Block Ramkrishnanagar Mysore-570022 Karnataka, India 8050944624 Fax: Email: [email protected] 7. Academic Details: (Degree, Post-graduation, PhD, DSc and other research qualifications) Degree B.Sc., M.Sc., Ph.D. Name of University J.S.S. College, University of Mysore Department of Botany University of Mysore University of Mysore Subject(s) Year of Passing Chemistry Botany Zoology Botany Botany 1993 1995 2004 KSLET- for Assistant Professorship Cleared on 2014 (Accredited by UGC) Title of Thesis: "In vivo, in vitro and Bioactivity studies of traditional and economically important medicinal plants" Research Experience: Designation Technical Assistant Institution Area of Research Mulberry mutation breed Department of Botany,University of Mysore through tissue culture Central Silk Board Sponsored method" Duration 1996-1997 Project Junior and Senior Research Fellowship Department of Botany,University of Mysore Manasagangotri,Mysore570006 "In vivo, in vitro and Bioactivity studies of traditional and economically important medicinal plants" 1998-2002 CSIRResearch Associate Department of Botany, Sri Krishnadevaraya Uinversity Anantapur, Andhra Pradesh Survey, Conservation and 2008 - 2010 Utilization of Bryophytes of Andhra Pradesh Undertaken by Prof. T. Pullaiah 8. Academic Distinctions like Gold Medals/Endowment/Memorial Lectures Delivered: 9. Honors and Awards: 1. Nagesh and Shanthamma C. 2001. Micropropagation of Curculigo orchioides Gaertn. An endangered anticancer Herb. National Conference on plant biotechnology helad at Warangal. Baggaed Best presentation Award. 2. Nagesh K.S. 2002 In vitro Propagation and antioxidant activity of Curculigo orchioides Gaertn. Selected and presented for Young Scientist Award Under Indian Science Congress Association held at Lucknow. 3. Nagesh K.S 2008. In vitro propagation and antioxidant activity of Curculigo orchioides Gaertn.Selected for Young Botanist Award under IBS held at Allahabad. 10.Teaching experience (years) : 12 years 11.Research experience (years) : 6 years 12.No. of Ph.D(s) and MPhil(s) guided 13.No. of Books/Monographs Written/Edited: : Nil : 02 Books Published 1. Sandhy Rani S., M. Sowghandhika, K.S. Nagesh, B. Shusheela, and T. Pullaiah. 2014. Bryophytes in Andhra Pradesh.ISBN 978-81-211-0867- 6.Bishen Singh Mahendra Pal Singh. Dehra Dun (India). 14. Membership in Scientific Associations: International Journal of Advanced Research in Biological Sciences Indian Botanical Society Indian science congress Bangalore Nano, Karnataka Science And Technology Editorial Board as Reviewer Life member Annual membership Annual Membership 15. Publications and Patents: Attached in separate sheets (Attach List of Publications and Patents with names of authors, impact factors and attach best 5 papers reprints and proof of filing patents, Attach separate sheets) PUBLICATIONS: Research papers: Books: Book chapters in edited book Published (15) Accepted/ in Press National International National International 06 09 01 04 - 15. Fellows to the National Academies: Nil 16. Achievements and Discoveries: Enclosing in separate sheets 17. A Critical Analysis of Highlighting the Discoveries of the Nominee not Exceeding 150 words (if necessary, attach separate sheets): Enclosing in separate sheets 18.Innovative Contributions of the Nominee to the Society (not exceeding 150 words) Enclosing in separate sheets Annexure-I Published/Accepted papers 1. Jagadish Chandra and Nagesh K.S. 1997. Micropropagation through nodal bud culture in mulberry (Morus indica) Cv. S-13. Journal of Swamy Botanical Club. 14; 102-105. ISSN 0256 - 9493 2. Nagesh K.S. 2008. High frequency of multiple shoot induction of Curculigo orchioides Gaertn. Shoot tip V/S Rhizome Disc Taiwania- international. Journal of life science. 53(3):242-247. ISSN 0372-333X 3. Nagesh K.S., Harish Nayaka., Shylaja M. Dharmesh., Shanthamma C. and Pullaih T. 2008 In vitro Propagation and Antioxidant activity of Curculigo orchioides Gaertn. Journal of Tropical Medicinal plants. 9(2): 404-410. ISSN: 1511-8525 4. Nagesh K.S. and C. Shanthamma. 2009. Antimicrobial activity of Curculigo orchioides rhizome extract on pathogenic bacteria. African Journal of Microbial Research 3(1): 05-09. (Impact factor 0.3). ISSN: 1996-0808 5. Nagesh K.S., Bhgyalakashmi, N and Shanthamma C. 2009. Role of Polarity in de novo shoot bud initation in Rhizome Disc of Curculigo orchioides Gaertn. and its encapsulation and storability in Acta Physiologia Plantarum 31:699-704. (Impact factor 1.2) ISSN: 0137-5881 6. Nagesh K.S., C. Shanthamma and T. Pullaiah 2010. Somatic embryogenesis and plant regeneration in callus culture of Curculigo orchioides Gaertn. Indian journal of Biotechnology.9: 408-413. (Impact factor 0.4). ISSN 0972-5849 7. Nagesh K.S. and C. Shanthamma 2011. Micropropagation and antioxidant activity of Mollugo nudicaulis Lam. Journal of Medicinal Plants Research Vol. 5(6), pp. 895-902, (Impact factor 0.5). ISSN: 19960875 8. Nagesh K.S. and C. Shanthamma 2011. Wound healing acivity of Mollugo nudicaulis Lam -In vitro derived callus V/S Field grown leaves. Journal of Herbs, Spices and Medicinal Plants:17(3): 275-284. (Impact factor 0.8). ISSN 1049-6475 (Print) 9. Sandhy Rani S., M. Sowghandhika, B. Shusheela, K.S. Nagesh and T. Pullaiah. 2011. Addition to the bryophytes of Southern peninsular India. J. Indian Bot. Soc. 90(1&2)75-79. ISSN: 0019-4468. 10. Prakasha., RaveeshaK.A., Rajashekar N., Nagesh K. S., 2012. Anthelmintic activity of Tinospora sinensis miers.(Stem and Callus Extract) International Journal of Pharmaceutical Research & Development 4(05): 024 – 028.ISSN 0974-9446 11. Vinay B. Raghavendra, Lokesh S., Nagesh K. S., Chandra Nayak, Niranjana S., Ramachandrappa. 2013. Induction of systemic resistance by biocontrol agents against bacterial blight of cotton caused by Xanthomonas campestris pv. Malvacearum J. Plant Pathol. 02 : 59-69. ISSN:2306-1650 12. Sowghandhika M., Nagesh K.S., Sandhy Rani S., Shusheela, B. and Pullaiah T. 2013. Hepaticae and Anthocerotae in Vishakapatnam district of Andhra Pradesh, India. Indian J. of Forestry. 36 (2) ; 261-265. ISSN 0971-9431 13. Vinay Basavegowda Raghavendra, Nagesh Kallahally Sugnanachar, Govindappa M., Lokesh Siddalingaiah. (2016). First report of leaf spot Caused by Cercospora apii Fresen of Tabebuia argentea in India. Int. J. Adv. Res. Biol. Sci. 3(7): 203205.ISSN 2348-8069 14. Nagesh K.S. and C. Shanthamma 2016. An overview on tissue culture studies of Curculigo orchioides Gaertn: An endangered multi-potential medicinal herb. Journal of Medicinal Plants Studies :4(3): 119-123 (ISSN: 2394 - 0530 15. Nagesh K.S. and C. Shanthamma 2016. Encapsulation of somatic embryoids of Curculigo orchioides Gaertn. and its germination. European Journal of Biotechnology and Bioscience:4(6): 38-42. Books Published 2. Sandhy Rani S., M. Sowghandhika, K.S. Nagesh, B. Shusheela, and T. Pullaiah. 2014. Bryophytes in Andhra Pradesh. ISBN 978-81-211-0867- 6.Bishen Singh Mahendra Pal Singh. Dehra Dun (India). Invited Book chapters Published 1. Nagesh K.S. and Shanthamma 2011. Studies on de novo shoot bud regeneration, organogenesis and somatic embryogenesis in Curculigo orchioides Gaertn.: An endangered medicinal herb. In :Plant Tissue culture : Emerging Trends. T. Pullaiah (Eds).Regency Publications New Delhi : 90-102.( ISBN 81-89233-69-6, ISBN 97881-89233-69-3) 2. Ramesh C., Lakshmi, H., Sugunna Kumari, S.,Pushpalatha C., Nagesh K.S., and Suresh Kumar C. 2011. Biotechnological Prospective of Mulberry and Silk worms. In: Application of Biotechnology in Sericulture. Venkatesh Kumar R. and Shyam Kumar V.(Eds). Studium Press (India) Pvt. Ltd. New Delhi : 43-70.( ISBN 978-9380012-48-3) 3. Nagesh K.S. 2012. Herbal antioxidants and antioxidant assays In: Encyclopedia of Herbal Antioxidants (Volumes1-3) T.Pullaiah (Ed).Regency Publications New Delhi.:1-36.(ISBN 978-81-89233-69-3) 4. Nagesh K.S. 2012. Antioxidant assays In: Encyclopedia of Herbal Antioxidants (Volumes1-3) T.Pullaiah (Ed).Regency Publications New Delhi.:1-36.(ISBN 978-8189233-69-3,70-9,71-6,72-3) Annexure-II A Critical Analysis of Highlighting the Discoveries of the Nominee IN VIVO, IN VITRO AND BIOACTIVITY STUDIES OF TRADITIONAL AND ECONOMICALLY IMPORTANT MEDICINAL PLANTS Despite the increasing use of medicinal plants, their future, seemingly, is being threatened by complacency concerning their conservation. Reserves of herbs and stocks of medicinal plants in developing countries are diminishing and in danger of extinction as a result of growing trade demands for cheaper healthcare products and new plant-based therapeutic markets in preference to more expensive target-specific drugs and biopharmaceuticals. To cope up with this alarming situation, the Plant biotechnology played important role in the mass multiplication and provide source for extraction of secondary metabolites. Therefore, the major objectives of the my research programme is to select important medicinal plants for in vitro propagation, extraction and evaluation of antioxidant activity,wound healing and hepatoprotective activity and antibacterial properties. In the present investigation two medicinal plant spices such as Mollugo nudicaulis Lam - a traditionally important medicinal plant and Curculigo orchioides Gaertn.- an endangered multipotential medicinal plant have been selected. M. nudicaulis (Molluginaceae) is a traditionally important wild medicinal herb. The leaves are used by Indian traditional practitioners for curing several disorders including whooping cough, jaundice and as antiseptic Although it is distributed in different geographical locations, collection of the plant material for extraction of drugs is a major task as this small herb grows only in localized areas during rainy season. Curculigo orchioides Gaertn. (Hypoxidaceae) is a valuable wild, endangered medicinal plant Indiscriminate and over exploitation also pushed this plant to the present threatened and endangered status. The PhD work emphasis on the following aspects I. In vitro studies of Mollugo nudiculis Lam. II. In vitro studies of Curculigo orchioides Gaertn. III. Comparative bioactivity studies using native (in vivo ) plant parts and in vitro derived callus extracts for 1. Antioxidant activity using in vitro assays 2. Hepatoprotective activity using animal models 3. Wound healing Activity using animal models 4. Antibacterial activity using pathogenic bacteria. Innovative Contributions of the Nominee to the Society Herbal drugs have been extracted from plant cultivated in fields or from their natural habitats. It has been reported that nearly 85% of plants used traditionally as ingredients in crude drugs are collected from natural habitats (22). Endemicity, restricted distribution, small population, availability in particular season have caused a decline in wild population. To overcome these, in vitro cultures could be used as alternative method. From our results, it can be suggested that in vitro derived callus of M. nudicaulis and Curculigo orchioides could be used as alternative to field grown plant for extraction of secondary metabolites throughout season. And also this biotechnological approaches help for conservation of the medicinal plants The in vitro derived calli have shown a remarkable for 1. Antioxidant activity using in vitro assays 2. Hepatoprotective activity using animal models 3. Wound healing Activity using animal models 4. Antibacterial activity using pathogenic bacteria and therefore hold promise for treating various ailment in humans after careful clinical evaluation studies The demand for herbal remedies has been increasing significantly. Constant demands for some of the medicinal plants have affected their availability to a large extent for extraction of secondary metabolites. The present findings are important and have implications in modern biotechnology, which can offer highly active antioxidants and antibacterial compounds for which there is great demand throughout the season. The protocol developed in the present investigation may serve as a basic tool for further exploitation of these two medicinal plants for further pharmacological applications and conservation for future needs.
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