LASER: Light Amplification by Stimulate Emission of Radiation The general properties of the laser beam: - Monochromatic: it is a unique light source emits a narrow beam of light of a single wave length. - Coherent: the laser waves are in phase with each other. - Collimated: the laser beam can be focused to a spot only a few microns in diameter. Sun Light LED Light Laser The principle of laser production Laser components: 1- Active medium: solid, liquid or gas where the absorption, stimulation emission take place. 2- Inversion population: a. Atoms in the ground state stimulated by an incident photon to the excited -3 state (metastable state) in 10 sec. b. The no. of excited atoms in the metastable state > ground state. c. The atoms tend to decay back to the ground level by spontaneous -6 -3 emission in (10 -10 )sec in each decay a photon released. d. The spontaneous emission leads to the amplification of the beam by the resonator. 3- resonator: which contain two parallel mirrors, the active medium placed between them. One of the mirrors cause total reflection, while the other cause a partial reflection. - The photon incident on the first mirror reflected totally along the axis of the resonator then hit the partially reflected mirror permits continuous amplification. 4- The generated photons are identical to the incident photons. Essential elements of lasers Resonator Mirror 100% reflectivity Laser medium Mirror <100% reflectivity Laser output Pumping Types of laser a. Pulsed Laser solid lasers: Ruby laser (λ= 694 nm) Nd:YAG Semiconductor b. Continuous Laser Gas lasers: Co 2 He-Ne argon laser Liquid lasers: dye, excimer. Ruby laser - In (1960) T.H. Maiman produced a laser from ruby crystal. - The ruby rod is aluminum oxide with some chromium atoms through it. - One end of the rod is covered completely with silver to allow light to escape. - The bright flash light causes the electrons in the chromium atoms of the rod to gain energy, which is released inside as a red light. - The red light is reflected back and forth between the mirrored surfaces at the end of the rods. - The light causes the chromium atoms to release more light photons. - The intensity of the red light beam increases and leaves the end of the half-coated end of the rod as a laser beam Laser Tissue Interactions: The wavelength and power output of a particular laser determines its medical applications, because the interaction between laser radiation and biological tissue depends on important parameters such as : - Laser Parameters - Tissue Parameters Irradiation Dose and power density of Laser Energy (J) • Power (W) = ----------------Time (sec) Irradiance; also called power density can be calculated as follows Power output (W) Power density (Irradiance) (W/cm²) = -------------------Impact spot Area (cm²) Treatment dose is the same as the energy density. Doses refer to the amount of energy per unit area, the dose is the most important treatment parameter Dose (J/cm²) = power density (W⁄cm²) × Time (sec) Energy density (J/ cm²) = power (W)× time (sec)/Area (cm²) of spot Skin Parameters: Skin components Epidermis - the outermost layer serves as the first layer of defense against the outside world. Cells at the surface are dead, and they fall off and away as upward pressure is applied by continuously multiplying cells in the lower epidermis Dermis - provides the skin's structural integrity, elasticity, and resilience; includes fibroblasts, capillaries, lymph nodes, sweat glands, hair glands, but only a few nerves and muscle cells Subcutaneous tissue - the thickness varies greatly; mostly fat or adipose cells, protects the body from cold and mechanical trauma Selective Absorption of Chromospheres Melanin: gives skin its tone or color. Darker skin has more melanin. Patients with darker skin may experience some destruction of melanin when the 1064nm light is absorbed, but it will re-generate by itself. Hemoglobin (blood): absorption of energy especially by 532nm H20 (water): absorption low for 532nm, very moderate absorption for 1064nm Classification of Lasers • By laser medium: gas (He-Ne, CO2, nitrogen lasers), liquid (dye laser), solid lasers (Ruby, Nd:YAG, Nd-glass, Er:YAG lasers) • By pumping method: flashlamp, electrical discharge, chemical actions • By operating mode: continuous-wave (CW), pulsed lasers • By wavelength: infrared, visible, ultraviolet, x-ray lasers Types of medical laser: 1- High power Lasers They are used in many surgical procedures to cut, coagulate and evaporate tissues. The power range for the surgical lasers is between (3000 to 10,000) mW, also it is known as ''surgical lasers''. It must be powerful enough to heat up the tissues to temperatures over 50 degrees Celsius. The most widely used are Nd:YAG and Co2 lasers. 2- Low Level Lasers (LLL) • The output power is between (1 to 500) mW • The typical wavelength is in the range 600-1000 nm (red to near infrared) • short-pulse-width devices are in the range of 1-100 W with typical pulse-widths of 200 ns • It is applied for relieving chronic joint disorders, neck pain, rheumatoid arthritis and wound healing • This low power will not damage the hydrogen bonds in the tissues and does not cause any change but the photochemistry effect. Stimulating a cell (increased in cellular metabolism) and the effects are biochemical, not thermal. Photons, which are particles of electromagnetic energy, are emitted from the low power laser. These particles enter the tissues and are absorbed in the mitochondria, which are tiny structures within the substance of each individual cell. The energy is converted to chemical energy within the cell. The permeability of the cell membrane changes which in turn produces various physiological effects. These physiological changes affect a variety of cell types including macrophages, fibroblasts, endothelial cells and mast cells. •
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