Mitosis
• During interphase, the DNA is not condensed and
individual chromosomes cannot be discerned
• As the cell enters prophase, the chromosomes
condense
• After DNA replication in S phase, each
chromosome has two DNA molecules, known as
sister chromatids
• Until they are separated during anaphase, the
chromatids are held together at a region called the
centromere
Vocabulary
Checkpoint
• Chromosomes: in Eukaryotes, a structure composed of
DNA and proteins that bares part of the genetic
information of the cell
• Chromatid: one of two identical chromosomal strands into
which a chromosome splits longitudinally preparatory to
cell division.
• Sister Chromatids: each pair of newly replicated
chromatids
• Centromere: the region where sister chromatids join
• Spindle: array of microtubules emanating from both poles
of a dividing cell during mitosis
• Centriole: a paired organelle that helps organize the
microtubules during cell division
Prophase
Metaphase
Anaphase
Telophase