Global Analysis of Protein Expression of Inner Ear Hair Cells

This Accepted Manuscript has not been copyedited and formatted. The final version may differ from this version.
Research Articles: Cellular/Molecular
Global Analysis of Protein Expression of Inner Ear Hair Cells
Ann E. Hickox1,*, Ann C. Y. Wong2,3,*, Kwang Pak2, Chelsee Strojny1, Miguel Ramirez1, John R. Yates4, Allen F.
Ryan2,** and Jeffrey N. Savas1,**
1
Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
2
Departments of Surgery & Neuroscience, University of California San Diego and Veterans Administration
Medical Center, La Jolla, CA, 92093, USA
3
Translational Neuroscience Facility, Department of Physiology, UNSW Australia, Sydney, NSW 2052, Australia
4
Chemical Physiology and Molecular and Cellular Neurobiology, The Scripps Research Institute, La Jolla, CA
92037, USA
DOI: 10.1523/JNEUROSCI.2267-16.2016
Received: 17 July 2016
Revised: 29 November 2016
Accepted: 19 December 2016
Published: 30 December 2016
Author contributions: A.E.H., A.C.Y.W., K.P., C.S., M.R., A.F.R., and J.N.S. performed research; A.E.H.,
A.C.Y.W., K.P., J.Y., A.F.R., and J.N.S. contributed unpublished reagents/analytic tools; A.E.H., A.C.Y.W., K.P.,
C.S., A.F.R., and J.N.S. analyzed data; A.E.H., A.F.R., and J.N.S. wrote the paper; A.F.R. and J.N.S. designed
research.
Conflict of Interest: The authors declare no competing financial interests.
*A.E.H. and A.C.Y.W. contributed equally to this work.
**A.F.R. and J.N.S. are co-last authors with equal contributions to the supervision of the work presented.
Research was supported by NIDCD R00 DC-013805 to J.N.S., VA Research Service BLS Grant BX001295 to
A.F.R., and the Garnett Passe and Rodney Williams Memorial Foundation Research Fellowship to A.C.Y.W.
J.R.Y. is supported by NIH grants P41 GM103533 and R01 MH067880. We are grateful to Jaime GarciaAñoveros, Ann Hogan, Kazuaki Homma, and Jing Zheng for helpful comments and feedback on manuscript
content and clarity.
Correspondence should be addressed to: Dr. Jeffrey N Savas, Department of Neurology, Northwestern
University, Feinberg School of Medicine, 303 East Chicago Avenue, Ward 12-102, Chicago, IL 60611-4296,
[email protected]; and Dr. Allen F Ryan, Department of Surgery, University of California, San
Diego, 9500 Gilman Drive #0666, La Jolla, CA 92093, [email protected]
Cite as: J. Neurosci 2016; 10.1523/JNEUROSCI.2267-16.2016
Alerts: Sign up at www.jneurosci.org/cgi/alerts to receive customized email alerts when the fully formatted
version of this article is published.
Accepted manuscripts are peer-reviewed but have not been through the copyediting, formatting, or proofreading
process.
Copyright © 2016 the authors
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