Additional table 1. List of genes involved in the degradation of aromatic compounds
Gene
Bpet0248
Bpet0249 pht4
Location
on GI
GI
GI
Product
Substrate
phthalate
Pathway
type
peripheral
Bpet0250 pht2
Bpet0251 pht5
Bpet0252 pht3
Bpet0253 bug5
Bpet0254 pcaG
GI
GI
GI
GI
GI
Bpet0255 pcaH
GI
Bpet0256 pcaQ
Bpet0257 pcaC
GI
GI
Bpet0258 pcaB
GI
Bpet0259 bug6
Bpet0260
GI
GI
MarR-family transcriptional regulator
4,5-dihydro-4,5-dihydroxyphthalate
dehydrogenase
phthalate dioxygenase reductase
4,5-dihydroxyphthalate decarboxylase
phthalate dioxygenase oxygenase
solute receptor
protocatechuate 3,4-dioxygenase, alpha
subunit
protocatechuate 3,4-dioxygenase, beta
subunit
LysR-family transcriptional regulator
4-carboxymuconolactone
decarboxylase
3-carboxy-cis,cis-muconate
cycloisomerase
solute receptor
LysR-family transcriptional regulator
protocatechuate
central
Bpet0304 mhaA
GI
3-hydroxyphenylacetate hydroxylase
3-hydroxyphenylacetate
peripheral
Bpet0509 mbhM
Bpet0510
Bpet0511 bug15
Bpet0512
Bpet0513 mhbI
Bpet0514 bug16
Bpet0515
Bpet0516 mhbH
Bpet0517 mhbD
Bpet0518
-
3-hydroxybenzoate 6-hydroxylase
FAD-dependent oxidoreductase
solute receptor
putative chorismate mutase
maleylpyruvate isomerase
solute receptor
FAD dependent monooxygenase
fumarylpyruvate hydrolase
gentisate 1,2-dioxygenase
LysR-family transcriptional regulator
3-hydroxybenzoate
peripheral
gentisate
central
Bpet0549 abmA
-
2-aminobenzoyl-CoA
central
Bpet0550 abmB
-
Bpet0551 abmC
-
Bpet0552 abmD
Bpet0553 abmG
Bpet0554
Bpet0555 abmE
-
2-aminobenzoyl-CoA
monooxygenase/reductase
putative beta-hydroxyacyl-CoA
dehydrogenase
putative enoyl-CoA
hydratase/isomerase
putative acyl-CoA dehydrogenase
2-aminobenzoate CoA ligase
thioesterase family protein
hypothetical protein
2-aminobenzoate
peripheral
Bpet0681
-
4-hydroxyphenylpyruvate dioxygenase
tyrosine
peripheral
Bpet1330
Bpet1331
GI2
GI2
unknown
unknown
peripheral
peripheral
Bpet1332
GI2
putative monooxygenase
putative (chloro)phenol
monooxygenase
TetR-family transcriptional regulator
Bpet1385 benE
Bpet1386 pcaK
GI2
GI2
benzoate:H+ symporter family protein
aromatic acid:H+ symporter family
protein
benzylalcohol
peripheral
Bpet1387 xylB
Bpet1388 xylC
GI2
GI2
benzylalcohol dehydrogenase
benzaldehyde dehydrogenase
Bpet1389
bug35A (pseudo)
Bpet1390 catC
Bpet1391 catD
Bpet1392 catF
(pseudo)
Bpet1393 catI
(pseudo)
GI2
solute receptor
GI2
GI2
GI2
muconolactone isomerase
3-oxoadipate enol-lactone hydrolasease
3-oxoadipyl CoA thiolase
GI2
3-oxoadipate CoA-transferase subunit
A
Bpet1394 benk
GI2
Bpet1395
Bpet1396 benD
GI2
GI2
Bpet1397 benC
GI2
Bpet1398 benB
Bpet1399 benA
GI2
GI2
aromatic acid:H+ symporter family
protein
hypothetical protein
cis-1,2-dihydroxycyclohexa-3,5-diene1-carboxylate dehydrogenase
benzoate 1,2-dioxygenase electron
transfer subunit
benzoate 1,2-dioxygenase beta-subunit
benzoate 1,2-dioxygenase alpha subunit
Bpet1400 catA
Bpet1401 catB
Bpet1402 catR
GI2
GI2
GI2
catechol 1,2-dioxygenase
muconate cycloisomerase
LysR-family transcriptional regulator
Bpet1427
Bpet1428 xlnD
Bpet1429 hbzF
Bpet1430 xlnE
Bpet1431
GI2
GI2
GI2
GI2
GI2
IclR-family transcriptional regulator
3-hydroxybenzoate 6-hydroxylase
putative maleylpyruvate isomerase
gentisate 1,2-dioxygenase
aromatic acid:H+ symporter family
protein
Bpet1512
Bpet1513
GI3
GI3
Bpet1513A
(pseudo)
GI3
short chain dehydrogenase
aromatic ring-hydroxylating
dioxygenase small subunit
aromatic ring-hydroxylating
dioxygenase, large subunit
Bpet1533 clcR
Bpet1534 clcA
Bpet1535 clcB
Bpet1536 bug36
Bpet1537 clcD
Bpet1538 clcE
Bpet1540
GI3
GI3
GI3
GI3
GI3
GI3
GI3
Bpet1541
GI3
Bpet1542
Bpet1543
GI3
GI3
Bpet1634
Bpet1635 pcaJ2
-
Bpet1636 pcaI2
-
Bpet1637
-
LysR family transcriptional regulator
chlorocatechol 1,2-dioxygenase
chloromuconate cycloisomerase
solute receptor
dienelactone hydrolase
maleylacetate reductase
aromatic ring-hydroxylating
dioxygenase small subunit
aromatic ring-hydroxylating
dioxygenase, large subunit
oxidoreductase
aromatic acid:H+ symporter family
protein
LysR-family transcriptional regulator
3-oxoadipate CoA-transferase subunit
B
3-oxoadipate CoA-transferase subunit
A
thiolase
catechol
central
benzoate
peripheral
catechol
central
3-hydroxybenzoate
gentisate
peripheral
central
chlorocatechol
central
unknown
peripheral
protocatechuate/catechol
central
Bpet1923 paaX
Bpet1924 paaA
Bpet1925 paaB
Bpet1926 paaC
Bpet1927 pcaD
Bpet1928 paaE
Bpet1929 paaZ
(pseudo)
Bpet1933 paaG
Bpet1934 paaI
Bpet1935 paaK
Bpet1936
Bpet2634 hpaH
(pseudo)
Bpet2635 hpaI
-
transcriptional regulator
ring-oxidation complex protein 1
ring-oxidation complex protein 2
ring-oxidation complex protein 3
ring-oxidation complex protein 4
ring-oxidation complex protein 5
ring-opening enzyme
phenylacetyl-CoA
central
-
enoyl-CoA hydratase
thioesterase
phenylacetyl-CoA ligase
acyl-CoA dehydrogenase
2-oxo-hept-3-ene-1,7-dioate hydratase
phenylacetate
peripheral
homoprotocatechuate
central
-
2,4-dihydroxyhept-2-ene-1,7-dioate
aldolase
Bpet2665
paaE/catF
-
beta-ketoadipyl CoA thiolase
protocatechuate/catechol
central
Bpet2781 tyrB
-
aspartate/tyrosine/aromatic
aminotransferase
tyrosine
peripheral
Bpet2803 ndsR
Bpet2804 ndsB
-
salicylate
peripheral
Bpet2805 ndsC
-
Bpet2806 ndsD
-
LysR-family transcriptional regulator
oxygenase large subunit of salicylate 5hydroxylase
oxygenase small subunit of salicylate 5hydroxylase
ferredoxin component of salicylate 5hydroxylase
Bpet3150 kynB
Bpet3151 kynA
-
kynurenine formamidase
tryptophan 2,3-dioxygenase
tryptophan
peripheral
Bpet3348 catR2
Bpet3349 catB
Bpet3350 bug66
-
LysR-family transcriptional regulator
muconate cycloisomerase
solute receptor
catechol
central
Bpet3568 boxA
Bpet3569 boxB
Bpet3570 boxC
Bpet3571 boxR
Bpet3572
Bpet3573 boxD
-
benzoyl-CoA
central
Bpet3574 bzdA
Bpet3575
-
benzoyl-CoA oxygenase component A
benzoyl-CoA oxygenase component B
benzoyl-CoA-dihydrodiol lyase
transcriptional regulator
unknown function
3,4-dehydroadipyl-CoA semialdehyde
dehydrogenase
benzoate CoA-ligase
Lactonase
benzoate
benzoyl-CoA
peripheral
central
Bpet3588
Bpet3589 bug74
Bpet3590 pcaI3
-
protocatechuate/catechol
central
Bpet3591 pcaJ3
-
Bpet3592 pcaR
-
LysR-family transcriptional regulator
solute receptor
3-oxoadipate CoA-transferase subunit
A
3-oxoadipate CoA-transferase subunit
B
transcriptional regulator
Bpet3730 tfdF
Bpet3731 tfdD
(pseudo)
GI5
GI5
maleylacetate reductase
chloromuconate cycloisomerase
chlorocatechol
central
Bpet3735 tfdE
Bpet3737 tecF
GI5
GI5
dienelactone hydrolase
2-hydroxy-6-oxo-2,4-heptadienoate
hydrolase
Bpet3738 tcbAa
GI5
tetrachlorobenzene
peripheral
Bpet3739 tcbAb
GI5
Bpet3740 tcbAc
GI5
Bpet3741 tcbAd
GI5
Bpet3742 tcbB
GI5
Bpet3743
GI5
Bpet3744
GI5
chlorobenzene dioxygenase alphasubunit
chlorobenzene dioxygenase betasubunit
chlorobenzene dioxygenase, ferredoxin
subunit
chlorobenzene dioxygenase, NADHferredoxin reductase
cis-chlorobenzene dihydrodiol
dehydrogenase
ring hydroxylating dioxygenase alpha
subunit
ring hydroxylating dioxygenase beta
subunit
Bpet3747 tcbR
Bpet3748 tcbC
Bpet3749 tcbD
Bpet3750 bug77
Bpet3751 tcbE
Bpet3752 tcbF
GI5
GI5
GI5
GI5
GI5
GI5
transcriptional regulator
chlorocatechol 1,2-dioxygenase
chloromuconate cycloisomerase
solute receptor
dienelactone hydrolase
maleylacetate reductase
chlorocatechol
central
Bpet4008 mhaA
-
3-hydroxyphenylacetate hydroxylase
large component
3-hydroxyphenylacetate
peripheral
Bpet4015
Bpet4016 hmgA
Bpet4017 hmgB
-
LysR-family transcriptional regulator
homogentisate 1,2-dioxygenase
fumarylacetoacetase
homogentisate
central
Bpet4463 kynU
-
kynureninase
tryptophan
peripheral
Bpet4527 pcaR
Bpet4528 pcaI4
-
catechol
central
Bpet4529 pcaJ4
-
Bpet4530 catC2
Bpet4531
Bpet4532 catD2
-
transcriptional regulator
3-oxoadipate CoA-transferase subunit
A
3-oxoadipate CoA-transferase subunit
B
muconolactone isomerase
conserved hypothetical protein
3-oxoadipate enol-lactone hydrolase
Bpet4737
-
putative phenylacetyl-CoA ligase
unknown
peripheral
-
methylcatechol