Argument for minimizing Insulin Use In normal physiology, liver sees

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Diabetes, Cardio-Metabolic Newsletter
Argument for minimizing
Insulin Use
8/15/2016
In normal physiology, liver sees 3 x more insulin (from portal system) than periphery to decrease hepatic glucose
productionThus to achieve even a modicum of decreased hepatic glucose production, exogenous insulin administration results in
hyperinsulinism
Thus strong argument for not using insulin early, but only after failiny 3-4 non-insulin treatments