From: Differential Uptake of Volatile Agents into Brain Tissue In Vitro :Measurement and Application of a Diffusion Model
to Determine Concentration Profiles in Brain Slices
Anesthes. 2003;99(1):122-130.
Figure Legend:
Fig. 5. Estimating the diffusion coefficients of F6 and halothane. Measurements of drug content in brain slices (from fig. 2) are
superimposed on derived average concentration profiles for diffusion into a 500-μm-thick tissue slice, for diffusivities ranging from
0.05 to 3.2 × 10−6cm2/s. (A
) The measured rate of F6 uptake (○ corresponds to a diffusion coefficient of approximately 0.1 × 10−6cm2/s. (B
) The measured rate of halothane uptake (•) corresponds to a diffusion coefficient of approximately 0.8 × 10−6cm2/s.
Date
Copyright
© 2017 American Society of Anesthesiologists. All rights reserved.
Data of
fordownload:
F6 (○ are7/31/2017
repeated from panel
A