Movement Across Cell Membranes Passive and Active Transport Movement Across Membranes There are several ways substances can move across the plasma membrane. Diffusion Osmosis Transport by proteins Endocytosis and Exocytosis Diffusion Diffusion is the movement of particles from an area of their Only small, uncharged molecules can diffuse across the plasma membrane Examples of substances that move across the plasma membrane by diffusion? Diffusion Osmosis Osmosis is the movement of water molecules from an area of their higher concentration to an area of their lower concentration across a membrane. This can also be described as the movement of water from a dilute solution to a concentrated solution across a membrane. Osmosis Tonicity Tonicity is a relative term Hypertonic solution: Membrane bound object is in a solution that has a of solute than the object Hypotonic solution: Membrane bound object is in a solution that has a of solute than the object Isotonic solution: Membrane bound object and solution have the of solute. *Label the boxes with arrows showing the overall direction of water flow Other molecules Small and uncharged molecules like O2, CO2, and H2O They are not the only things the cell needs to move. How might these move through the membrane? Method 1: Proteins for Transport Membrane transport There proteins (integral proteins) can be used to are two ways they do this job. Method 1: Proteins for Transport Facilitated diffusion Channel or carrier proteins provide a pathway for substances to move down their concentration gradient (from high concentration to low concentration) Active Carrier Transport proteins (also called pumps) use energy from ATP to move substances up their concentration gradient (from low concentration to high) Facilitated Diffusion Facilitated Diffusion Molecules are moving (diffusion) But they are being facilitated in that movement by an integral membrane protein. They move through a Diffusion, Osmosis, and Facilitated Diffusion are all examples of Passive Transport across membranes Active Transport Active transport is called “active” because it is something the cell is actively and intentionally doing, and it’s using energy to do it. It is defined as using the energy from ATP to move substances (from low concentration to high concentration) Active Transport Active Transport: Sodium-Potassium Pump as an example *Mark on the dia gram where the areas of high concentrations of Na+ and K+ are. Sodium Potassium Pump Method 2: Endocytosis and Exocytosis These processes use vesicles (little sacs formed by parts of the membranes) to transport substances in and out of the cell. Endocytosis: Transport of large molecules by the “engulfing” action of the cell membrane & the formation of a membrane bound vesicle Exocytosis: - vesicles formed within the cell fuse with the cell membrane, emptying their contents into the extracellular environment Membrane Fluidity One result of the plasma membrane’s fluidity is that parts of it can pinch off to form vesicles, and vesicles can travel to another part of the cell and join the membrane there. In this way vesicles are used to transport materials around the cell, especially from the rER to the Golgi, and from the Golgi to the plasma membrane This is how some products exit and enter the cell Vesicles, exocytosis and endocytosis Review: Make a flow chart to display the methods of moving substances across membranes you’ve learned. Use the diagram on the next slide to organize the information. You’ll need to add textboxes as you go. Flowchart Active Transport Transport in membranes Passive Transport
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