Healthcare Innovation Global Leader in Cognitive Science Prepares To Launch New Online Memory Assessment Overview Country or Region: Canada Industry: Healthcare Customer Profile Cogniciti is a for-profit joint venture between Baycrest, the world’s healthcare leader in the study of memory and aging, and MaRS, Canada’s premiere innovation center. The company is based in Toronto, Ontario. Business Situation Cogniciti is delivering an Online Memory Assessment to help adults determine whether their forgetfulness is due simply to normal aging or whether they should see a doctor. Cogniciti is a for-profit joint venture between Baycrest, the world’s healthcare leader in the study of memory and aging, and MaRS, Canada’s premiere innovation center. Cogniciti’s mission: to commercialize the very best brain health science from Baycrest and other leading healthcare institutions. In the fall of 2012 Cogniciti partnered with the Baycrest Foundation and a leading Baycrest scientist to release Mindfull, a how-to book on the science of nutrition and brain health. This work was first published in e-book form and hit the best sellers list in Canada. In September 2013 Harper Collins will bring the printed version to stores across North America. In the fall of 2013 Cogniciti will release its second product: an online brain health assessment which will help adults around the globe answer the question “Is my memory healthy or should I see my doctor?” This tool will be a world’s first: a private, athome, clinically researched assessment designed for adults age 50 to 79 who are struggling with whether their forgetfulness is simply normal aging, a mood disorder such as anxiety or depression, or the early signs of dementia. Its aim: drive earlier diagnosis and treatment of brain health issues thereby improving the outcomes for patients while lowering the costs to healthcare funders. “Brain health is the next frontier. Our aim is to dramatically improve the years and quality of life of our aging population by revolutionizing the early detection of disease.” Michael Meagher, President, Cogniciti Situation Located on a 22-acre campus in Toronto, Ontario, Baycrest is a global leader in the field of brain health and aging. In 2009 Baycrest partnered with MaRS, the leading Canadian innovation center, to commercialize brain health assessment, management, and rehabilitation solutions based on the science of Baycrest and other respected sources. The for-profit venture— called Cogniciti—operates with a small executive team that is supported by the talents of dozens of professionals at Baycrest, MaRS, and beyond Michael Meagher, President of Cogniciti, explains why Baycrest is involved in a commercial venture. “Virtually all public hospitals in Canada are facing financial challenges and are looking for ways to keep providing superior healthcare despite those challenges,” he says. “Over the years Baycrest has done an amazing job on the fundraising front. With Cogniciti and other ventures, Baycrest is innovating by commercializing its intellectual capital to add new revenue streams.” The current focus for Cogniciti: an online screening tool for memory loss. “Baycrest doctors and scientists tell us that a natural part of aging is that our memories and attention spans become less acute,” explains Meagher. “The key issue is determining when simple forgetfulness becomes something more serious. Because the early-stage symptoms for memory loss due to aging, memory loss due to highly treatable conditions such as anxiety or depression, and memory loss due to serious diseases such as Alzheimer’s are so similar, people tend to delay getting checked out—often for years. And during that time, many live in fear that their condition is Alzheimer’s, the world’s second most-feared disease after cancer. Those delays cause needless worry for the well and make treatment tougher for those with an illness. Our mission is to help eliminate the delays.” By late 2011, Cogniciti completed most of the clinical work required to adapt the three-hour battery of tests used by doctors to a 25-minute, self-administered assessment. The company then began looking at how to transition that assessment—running on a PC in a lab environment at the time—to the web. Since then Cogniciti and Baycrest scientists have progressed the clinical research such that, in spring 2013, they are in the final stages of norms collection. The project team is working to release a first edition of the assessment in the fall 2013. Solution By thinking creatively, Cogniciti has avoided the typical challenge of finding enough willing test subjects. “Getting volunteers for clinical research usually takes a lot of time and money; a good hospital is lucky to get a few dozen a week,” says Meagher. “We took a different approach, reaching out to a large media outlet that targets people aged 40 to 80 and enlisting its aid in finding people who want to help us ‘make a difference.’ We received more than 1,000 volunteers in the first four days, which validates that people are hungry for what we’re working to deliver. Over the course of our research we have built a volunteer base of more than 2,000 non-paid adults, all giving of their time to help us create the next break-through in brain health.” Anonymous Screening Tool After registering anonymously, people will be presented with six exercises, each lasting a few minutes and proven in the lab to be good indicators of the two cognitive areas most affected by age: memory and attention span. The test results will be used to generate an overall assessment of the person’s brain health, calibrated to account for age and educational background. A personalized report will then be immediately presented to the test-taker that answers the question, “Is my memory normal or should I be seeing my doctor?” “Think of the Online Memory Assessment as a thermometer for the mind,” says Meagher. “Most of us use a thermometer when we’re feeling poorly to help understand whether our temperature is high enough to warrant a call to the doctor. In the same way, the Online Memory Assessment helps us understand whether our memory problems are simply the result of normal aging or whether we should see a doctor.” Meagher expects most test-takers to fall into the ‘worried well’ category—that is, people with healthy brains who are concerned about the forgetfulness that comes to most of us as we get older. “For these people, we’re hoping that the Assessment will put their minds and the minds of their family members at ease,” says Meagher. “If the results fall outside the norm for someone’s age and education, the Assessment will provide a clear, step-bystep path for how to best prepare for a visit to the doctor including a report specifically designed for primary care professionals. Good preparation can make the doctor’s diagnosis faster and better, which is exactly what most patients are looking for.” Cogniciti is now evaluating commercialization models. It sees an opportunity with pharma and other large companies to use its assessment to help drive earlier treatment and better patient outcomes. The Online Memory Assessment offers one important step for business and government to effectively address the personal and economic costs of brain health issues. As he looks forward Meagher envisions other uses of the Assessment. Evolving the tool for use by primary care health workers is one such opportunity. As is adding a suite of science-based digital solutions for those with declining memories or family care issues. Books such as Mindfull fit this model as do other Baycrest products such as education courses for family caregivers and digital versions of Baycrest’s best interventions to help adults deal with common memory issues such as remembering faces and names. “Dementia is both a major emotional and economic issue. ” Michael Meagher, President, Cogniciti Benefits Dementia Is Both A Major Emotional and Economic Issue Emotional: Alzheimer’s is the world’s second most feared disease. 91% of adults want an annual, private brain health test but there is nothing easily available. So, adults delay seeing their doctors, on average one to three years. Cogniciti is going to change that. Economic: The total Canadian economic burden of dementia over the next 30 years is $872 billion according to a recent major study. The savings by delaying dementia by 2 years is $219 billion. Cogniciti is going to make that happen. Valuable New Screening Tool Through its efforts, Cogniciti is delivering a screening tool that is easily accessible, can be used in the privacy of peoples’ own homes, and will be of benefit to all who use it. “Regardless of the test results, the earlier an assessment is done, the better the outcome,” says Meagher. “People who test normally can rest at ease knowing that nothing is wrong, and people whose memory function may be impaired due to treatable issues such as sleep apnea can work with a physician to address those issues. People who, upon further diagnosis, are found to be in the early stages of dementia can start learning coping techniques, get a head start on understanding the issues they face, and begin exploring their options for treatment.”
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