Acid and heat stable enzymes for industry
Enzymes are used everywhere
Enzymes are used everywhere
Industry is boxed in by traditional enzymes
Temperature (C)
120
•Industrial Cleaning
•Industrial Cleaning
•Cellulosic Biofuels
Biofuels
•Cellulosic
80
40
Traditional enzymes
0
0
2
Acidic
4
6
8
pH
10
12
Alkaline
14
The CinderBio advantage
Temperature (C)
120
•Biofilms
80
•Cellulosic Biofuels
40
Traditional enzymes
0
0
2
Acidic
4
6
8
pH
10
12
Alkaline
14
The CinderBio advantage
Temperature (C)
120
•Biofilms
80
•Cellulosic Biofuels
40
Traditional enzymes
0
0
2
Acidic
4
6
8
pH
10
12
Alkaline
14
CinderBio’s advantages
 Works in extreme conditions where other
enzymes do not
 Exciting new applications
 Reduce complexity in some applications
 Reduce capital and operating expenses
 Up to 100x faster reaction speeds
 Longer half-lives  lower enzyme
replenishment costs
The CinderBio team
• Patent filed for
technology platform
(through UC/LBNL)
• Setting up customer
trials
• Incorporated in 2012
Steve Yannone
Jill Fuss
Founder and CEO
Founder and CTO
Matt Penfold
MBA 2014
Spencer Kellogg
MBA 2014
Meera Atreya
PhD student,
Chemical Biology
Alexandra
Pressman
JD 2014
Kareem El
Muslemany
PhD student,
Chemistry
Market screening
Industry attractiveness
Technical
fit
Path to market
Short term
target market
Source: IbisWorld; Advanced biofuels market is from IEA for 2030
Long term
target market
Short term target market
Biofilm removal
Short term target market
Biofilm removal
Enzyme cleaning for dairy
CinderBio’s value proposition
$60K of avoided
downtime per
dairy plant per day
Attractive economics for dairy
$60k of avoided downtime per plant per day
$15k revenue per plant per day
(assuming we price to capture 25% of this value)
$5k/plant/day to produce enzymes
$10k profit per plant per day
Dairy market opportunity
• Price: $15k per plant per day
• $1B potential enzyme
market
-US has 180 large dairy
plants
• For comparison
-US dairy market: $38B
-US enzymes market: $2.5B
Enthusiastic response from the dairy industry
1
Setting up trials with a
dairy lab in a large
university
2
$6B Chemicals Co
eager to distribute for
dairy applications
3
$20B Cleaning Co to
distribute for other food
applications
Path to market
Short term
target market
Source: IbisWorld; Advanced biofuels market is from IEA for 2030
Long term
target market
US food industry cleaning – beyond dairy
US milk sales:
$38B
US meat sales:
$209B
US vegetable
sales: $25B
US juice sales:
$23B
US soda sales:
$20B
US beer sales:
$28B
Source: IbisWorld
Path to market
Short term
target market
Source: IbisWorld; Advanced biofuels market is from IEA for 2030
Long term
target market
Why biofuels?
We want to continue doing all of this…
…without the resulting environmental impact…
…by converting plant matter into fuels
Long term target market
Cellulosic sugar production for biofuels and bio-based chemicals
Combined pretreatment
and
Enzymatic
conversion
enzymatic conversion
Acid pretreatment
Capex savings from eliminating a step
Opex savings from more active enzymes
with longer half-lives
Building a biofuels plant takes time
Growing through alliances
Development
Partnership 1:
Dairy Cleaning
Development
Partnership 2:
Non-dairy
Food/Bev.
Cleaning
CinderBio
Time
Development
Partnership 3:
Advanced
biofuels
Progress to date
 Setting up dairy cleaning trials and in
conversations with enzyme distributors
 Scaled system to 600L
 Recently filed for full patent
 Signed exclusive option to license
technology from UC/LBNL
Our vision for a cleaner future
Questions?